Delivering precision

Advanced engineering solutions
for stereotactic neurosurgery

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Table of contents Advancing medicine through innovative technologies 4 neuro | inspire surgical planning software 6 neuro | mate stereotactic robotic system 8 ™ ® neuro | guide guide tube kit 10 Renishaw healthcare solutions 12 ™ ® References 14 3 .

“As neurosurgeons we operate a bit like pilots and the neuromate® is my autopilot and my GPS during the surgery guiding me precisely to the planned structure in the brain.Advancing medicine through innovative technologies Meeting tomorrow’s demands today neuro | inspire™ Renishaw is applying precision engineering technology to the challenges of functional neurosurgery.renishaw. www. provides comprehensive product and support information. Rapid service that keeps you operating neuro | guide™ Renishaw recognises how much hospitals rely upon our products to keep neurosurgery clinics running smoothly. France ” . stereoelectroencephalography (SEEG) and targeted drug delivery. improving patient outcomes through accurate delivery of implantable devices. 2. Our aim is to help leading clinicians to enhance the safety and cost-effectiveness of their procedures.” Our website.com/neuro.4 Precision-guided neurosurgery 5 using our products help clinicians 6 to meet the challenges of developing life-enhancing therapies.1. for our captial equipment. CHUR Roger Salegro. Lille. that will ensure interruptions to your service are kept to a minimum. 3 neuro | mate® Our solutions are aligned with current and emerging therapy technologies such as deep brain stimulation (DBS). 4 Professor Cuny Head of general stereotactic and functional neurosurgery. That is why we offer comprehensive service level agreements and support contracts.

Frenchay Hospital.” “ Professor Steven Gill Consultant Neurosurgeon. Bristol. UK 5 .“The combined capability of accurate image-guided planning and the precision delivery that Renishaw’s robot can provide will lead to a major advance in neurosurgery.

• Ability to transfer plans between neuroinspire stations . Oxford. Checking neuroinspire™ surgical planning software is designed specifically to enable efficient. • The use of a customisable catalogue of implantable devices and tools.enabling you to plan away from your office or collaborate with remote colleagues. • Ability to use the stereotactic arc configuration that best suits your surgical plan. or in collaboration with colleagues. • Ability to turn any planning view from a set of 2D slices into a 3D volume. Defining A 4. It is a far more sophisticated program than any I’ve seen on the market today. clear-cut planning of stereotactic neurosurgical procedures with the Elekta AB Leksell® or Radionics CRW™ frames. th trajectory pa port 5. For anyone considering it for their unit. John Radcliffe Hospital. it makes a great piece of kit. 1.” Professor Tipu Aziz Consultant Neurosurgeon.com 6 “The neuroinspire™ software planning station is the latest one to come out in many years (Spring 2012). Contact us for more information about our latest set of functionality T +44 (0)1453 524777 F +44 (0)1453 524901 E neuro@renishaw. while on the move. Co-regist Planning at your convenience neuroinspire™ can be provided on a laptop or desktop computer. home. enabling you to plan from your office. Output re ration 2. UK ” . Planning Functionality to meet your needs Here are just some of the features neuroinspire™ can provide you with: • Ability to view DICOM formatted CT and MR series including angiographs to help to locate and avoid key blood vessels during your surgical planning.neuro | inspire™ surgical planning software Planning for the future? C-PC 3.

John Radcliffe Hospital.“neuroinspire™’s visualisation of 3D data is second to none.” “ Alex Green Consultant Neurosurgeon. it has helped me increase the precision to which I deliver DBS electrodes. reliably and repeatably. Oxford.” “ Julian Evans Consultant Neurosurgeon. Salford Royal Hospital. UK 7 . UK “neuroinspire™ is intuitive to the needs of the surgeon and gives me the confidence to accurately and safely target deep brain structures.

Milano. stereoelectroencephalography (SEEG). France 8 ” . wherever possible.” Professor S Blond Head of general stereotactic and functional neurosurgery.7 It is used in centres for applications such as deep brain stimulation (DBS).10 Before the installation of a neuromate® system. as well as diagnostic procedures. Lille. In our centre. CHUR Roger Salegro. neuroendoscopy. biopsies.neuro | mate® stereotactic robotic system Robot assisted neurosurgery Adapting to your workflow The neuromate® system is a consistent. “In stereoelectroencephalography (SEEG) we place up to 20 intracerebral electrodes in order to identify the epileptogenic zone and map eloquent structures. our engineering team will evaluate your surgical workflows and. we use it on a very regular basis for all our stereotactic procedures such as DBS.” Dr. SEEG etc. Thanks to the use of the neuromate® system. provide solutions to ensure optimal integration into your method of surgery. biopsies8 and also many research applications. Francesco Cardinale Neurosurgeon. Italy ” “The neuromate® system is a highly reliable and accurate tool which is well integrated into our surgical workflows. accurate and repeatable platform for therapy delivery. every target can be reached with a combination of speed and submillimetric accuracy. Epilepsy and Parkinson Surgery Centre “Claudio Munari”.9.

UK 9 .“The precision of robotic guided stereo EEG has revolutionised surgery to cure epilepsy. allowing us to offer cures to a whole new cohort of patients” “ Mr David Sandeman Consultant Neurosurgeon. Frenchay Hospital. Bristol.

whether you are targeting the subthalamic nucleus (STN). Radionics CRW™ enabling clamp 10 . the target position can be verified to reduce the effects of brain shift on placement accuracy. the thalamus (TH) or the ever more challenging pedunculopontine nucleus (PPN).11 neuro | guide™ with the Elekta AB Leksell enabling clamp neuroguide™ can be integrated into your existing practice.neuro | guide™ guide tube kit Aiming high Renishaw’s neuroguide™ electrode introducer kit allows you to implant and guide DBS electrodes to targeted anatomy within the brain. By requiring fewer trajectories through the approximate target volume. surgery times and the risk of haemorrhage are both reduced. used in combination with or instead of microelectrode recording. the neuroguide™ remains in place so you can deliver positional accuracy without having to repeat the full stereotactic procedure. All this enables you to obtain precision and accuracy. Using MRI. benefiting you and your patient. In the event of a revision. saving time and money. the globus palladus interna (GPi).

reduces operative time and haemorrhage risk. It provides clear verification of DBS implant position with minimal artefact. Salford Royal Hospital. UK 11 .“The neuroguide™ system allows for accurate and safe DBS implantation. and in the event of a revision allows for re-insertion without having to repeat the stereotactic procedure.” “ Julian Evans Consultant Neurosurgeon.

Renishaw Raman spectroscopy systems are used to identify and characterise the chemistry and structure of materials in a non-contact. position sensing. . forensic science.Renishaw® healthcare solutions Evolving our clinical focus A track record of 40 years of investment into cutting edge research and development has led to the provision of products and novel solutions in fields such as industrial metrology. pharmaceuticals. a manufacturer of specialist electrodes and instruments for use in functional and stereotactic neurosurgery. polymer. Our innovative solutions provide micrometre and even nanometre resolution dimensional measurement. development of new drugs. leading manufacturers rely on Renishaw technologies to deliver productivity through enhanced precision and process consistency. non-destructive manner. Diversification into the provision of precision health care systems is central to our recent and ongoing success. Precision in everything DIXI medical Spectroscopy Whether they make Formula 1® engines. dentistry and cancer diagnosis. semiconductor and chemical research. forensic science and oncology diagnosis. aircraft wings or artificial knee joints. 12 Potential applications include pharmaceutical. motion control and spectroscopy in a wide range of industries. Today many of the world’s manufacturers rely on our technologies to deliver productivity through enhanced precision and process consistency. Renishaw is an approved distributor of DIXI medical. For further information contact our sales team.

ultimately. From patient-specific implants to.Renishaw diagnostics Renishaw dental 3D printing Renishaw Diagnostics is evolving its Raman spectroscopy expertise to further product development for therapeutic and medical research applications. volume production of implants featuring hybrid structures and textures. 13 . but fits well. laser melting has the potential to unlock manufacturing capabilities that combine free-form shapes and intricate lattice structures that improve osseointegration. Renishaw Diagnostics mandate is to develop an effective suite of molecular-level medical diagnostics solutions. as well as the aerospace and high technology engineering and electronics sectors. Renishaw Diagnostics will be launching its tracelevel detection technologies as part of an evolving portfolio of in-vitro diagnostic products. Renishaw has applied its renowned cuttingedge engineering technology to its dental CAD/CAM system. the result is a crown or bridge that not only looks great. Renishaw’s laser melting process is an emerging manufacturing technology with a presence in the medical (reconstructive) industry. Focusing on precision at every stage.

S. 2013. Woolley. Derrey. 2012. Lancaster.. Fox. K. 59 (ONS Suppl 4). no. 7. Schiariti. no.. Procaccini. 3. Brain Mapp. B. 10. Pandya. Casaceli. 8. L. Flintham. Narayana. R. 8. N.” Neurosurgery. and S. N. 1459–65. Fox. 22. pp. P. Gill.” Neurochirurgie. 2. A. “Use of the NeuroMate Stereotactic Robot in a Frameless Mode for Movement Disorder Surgery.. Safety. S. H. 4. pp. P. Gong. M. K. Harrison. and P. H. “Stereoelectroencephalography: Surgical Methodology. 7. S. Miserocchi. vol. vol. 353–366. P. H. “Management of cystic craniopharyngiomas with stereotactic endocavitary irradiation using colloidal 186Re: a retrospective study of 48 consecutive patients. pp. M. F. Touzet. Tandon. Dellaretti.” vol. and Stereotactic Application Accuracy in 500 Procedures. 155. 2. R. S.. Patel. N.” Comput. 2002.. M. vol.” Acta Neurochir. Dubois. S. 5. G. and N. Gill.” Neurosurgery. 363–7. Gauthier. Touzet. L. D. 704–5. Littlechild.. 2013. “A magnetic resonance imaging-directed method for transventricular targeting of midline structures for deep brain stimulation using implantable guide tubes. N. Li. Fletcher. 1045–52. no. no. pp. no. pp. “The application accuracy of the NeuroMate robot--A quantitative comparison with frameless and frame-based surgical localization systems. P. Ayachi. P. and O. 90–8. S. T. and S. and S. Reyns. Maurage. M.. 234–7. S. Cossu. . O’Sullivan. 6. S. R. Diaz. 1. 6 Suppl Operative. Delalande. Blond. pp. Eldridge. A.. Varma. Cardinale. 2010. C. 63. Gusmão. “Column-based model of electric field excitation of cerebral cortex. M. Funct. vol. Q. P. Neurosurg. G. J. Kochunov. and G. Fuschillo. no. N. P. Sinnott. “Use of robot-guided stereotactic placement of intracerebral electrodes for investigation of focal epilepsy: initial experience in the UK. Perez. vol. Park. G. pp. B. N. 2003. 9. Prakash. 72. Steiger. Arnulfo. “Stereotactic robot-guided biopsies of brain stem lesions: Experience with 15 cases. Sandoval. Carpentier. and S. Neurosurg.. C. Haegelen.” Neurology. Khan. Reyns. L. “Stereotactic Biopsy for Brainstem Tumors: Comparison of Transcerebellar with Transfrontal Approach. N.. E. Blond.” Br. 27. vol. C. Javed. and F. 5. Abhinav. 56. U. Touzet. Fox. pp. S. pp. pp. S. Moscato.. 2008.. 2010. Castana. F. 2006. P. vol.” Neurosurgery. (Wien). vol. L. 11. Lowis. 5. “Surgical management of hypothalamic hamartomas with epilepsy: the stereoendoscopic approach. Zamorano. 1–14. Barua. S.” Hum.References 14 1. S. Sandeman.” Stereotact. Lo Russo. 66. Aided Surg. 6. 90. Reyns. Blond. A. no. J. and J. P.. Dhellemmes. 2. T. Pereira. vol.. Bulteau. 3. and D. discussion 1052–3. no. R. J. G. C. “Robot-guided convection-enhanced delivery of carboplatin for advanced brainstem glioma. 79–83. no. K. S. pp.. 132–135. R. M. Caborni. G. 2004. 15–18. A. 2013. Forster. A. S.

Global prescence and support .

neuromate® and neuroguide™ products are CE marked products and are only for use in countries that accept the CE marking. Formula 1® is a registered trademark of Formula One Group. Wotton-under-Edge. New Mills.com/neuro For worldwide contact information please visit www. GL12 8JR United Kingdom T +44 (0)1453 524777 F +44 (0)1453 524901 E neuro@renishaw. © Renishaw 2013. Apply innovation is a trademark of Renishaw plc. CRW™ is a trademark of Integra Radionics Inc. RENISHAW® and the probe emblem used in the Renishaw logo are trademarks of Renishaw plc in the UK and other countries. neuroinspire™ is a trademark of Renishaw plc.com www. Gloucestershire. neuroguide™ is a trademark of Renishaw plc. All rights reserved. H-4149-0007-A2 . Printed in England 1013 UK Part No. neuromate® is a registered trademark of Renishaw mayfield SA.renishaw. DIXI medical is a brand name of DIXI microtechniques. Leksell stereotactic system® is a registered trademark of Elekta AB.com/contact Note: neuroinspire™.Renishaw plc.renishaw.