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Quiz 9

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Dr. Damilola Akinmade


Dr. Sherket Peterson

Dr. Damilola Akinmade

Dr. Theresa Geiman

Dr. Theresa Geiman


Dr. Xin Yi Chan
Dr. Irene Aninye

Dr. Jessica Whitt

Dr. Rebecca Brogan

Unless otherwise noted, standard multiple choice questions are worth 1.5 points each. True/false questions are
worth 1 point each. Other point values are shown. For multiple choice and matching questions choose the best
response.
1. The gene for a repressible enzyme is turned off when
A. CAP is inactive.
B. the end product of a metabolic pathway the enzyme is used in is absent.
C. the end product of a metabolic pathway the enzyme is used in is present in very high
concentrations. (example the trp operon)
D. the substrate is absent.
E. the substrate is present in very high concentrations.
2. (1 pt) The trp operon is controlled by ______________ gene regulation.
A. negative
B. positive
3. (2 pts) Escherichia coli in your gut finds itself in an environment that is high in both glucose and
lactose. Regarding the lactose operon, which of the following are true? Select all that apply. Minus
one for the first incorrect response. Minus two for two or more incorrect responses.
o The lactose operon will be turned on a little (a little lac mRNA synthesized).
o Active CAP will be present in E. coli cells.
o The presence of the substrate will inactivate the lac repressor.
o The operator for the lac operon will be turned on completely.
4. Methylation of cytosine nucleotides in a eukaryotic gene will most likely
A. cause the DNA structure of that region to take on a more loose structure, such as that of a 30-nm
fiber.
B. increase the mutational frequency of that gene.
C. not have any effect on either the DNA structure or the transcription of that gene.
D. reduce transcription of that gene.
E. target the DNA for degradation.
5. (1 pt) List two of the four components that make up the eukaryotic transcription initiation complex.
Hint: All four of these are proteins.
Any two of: DNA bending protein
mediator proteins
specific transcription factors
general transcription factors
RNA polymerase II (technically this is not a part of the transcription initiation complex
but we accepted it)

6. Which of the following best describes how eukaryotes activate multiple genes, the products of which are
all involved in a similar process or pathway.
A. The genes are grouped together on a single chromosome.
B. The genes are grouped together in operons and are controlled by a single promoter.
C. The genes are located on different chromosomes, but congregate at sites rich in transcriptionassociated proteins.
D. Transcription and translation occur simultaneously.
7. (1.5 pts) Components, such as mRNA or proteins, within the fertilized egg that get distributed unevenly
in the two cells after a mitotic division and begin to determine what those two cells develop into are
called cytoplasmic determinants.