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Liver Disease Management & Transplant

Liver Disease Management & Transplant

2340 Clay Street, 3rd Floor
San Francisco, Calif. 94115
Tel. 415-600-1001
Tel. 415-600-1020 (hepatologists)
Tel. 415-600-1010 (surgeons)
The Liver Disease Management & Transplant Program provides a comprehensive program for adult liver disease management, end-stage disease
treatment and transplantation. Our team emphasizes early referral for evaluation before multiple or advanced complications develop due to liver
disease. We conveniently bring our specialists to local communities in Northern California and Nevada and support our patient care with the latest
advancements and research.
Among the services we provide include:
* Hepatitis B and C disease management
* Liver cancer management
* Liver transplant evaluation, transplant and post-transplant care
* Liver disease management and treatment
* Hepatitis and HIV co-infection treatment
* Complex hepatobiliary surgery
* Clinical trials for hepatitis B and C, liver cancer and liver assist devices
* Testing and management of fatty liver, autoimmune, genetic and metabolic liver disease

Our Team
Our liver disease and transplant physician staff includes hepatologists and surgeons who are members of the Physician Foundation at California
Pacific Medical Center (PFCPMC). PFCPMC is committed to bringing the highest quality health care to the communities we serve through outreach
clinics, education, and research and development.
Maurizio Bonacini, MD is a hepatologist and Director of the HIV Liver Clinic at California Pacific Medical Center.
Dr. Bonacini is also Associate Professor of Clinical Medicine at UCSF. His research interests include HCV and HIV
coinfection, and liver fibrosis and progression in HCV patients. He is a co-investigator for the DILIN group, a
National Institutes of Health-supported research group on drug-induced liver injury. Dr. Bonacini received his
training at University of Southern California's Liver Unit, Booth Memorial Medical Center (affiliated with New York
University Medical Center), and Universite Catholique de Louvain (Brussels, Belgium). He is board-certified in
internal medicine and gastroenterology. Dr. Bonacini speaks Spanish, Italian and French. Phone: (415) 600-1020.

Natalie Bzowej, MD, PhD is a hepatologist and Director of the Hepatology

Research Center at California Pacific Medical Center. Dr. Bzowej holds her M.D.
and Ph.D. in pharmacology from the University of Toronto and completed her
gastroenterology fellowship at UCSF. She is board-certified in internal medicine
and gastroenterology. Dr. Bzowej works in partnership with our hepatology team to
manage the care of patients with acute, chronic and end-stage liver disease. She
is in charge of the Clinical Research Trial Program and has an interest in chronic
hepatitis B and C. Phone: (415) 600-1020.

Stewart Cooper, MD is a physician scientist and hepatologist. He directs hepatology and liver transplantation
research, and and the Liver Immunology Laboratory at California Pacific. Dr. Cooper
investigates hepatic immunity, focusing on the determinants of HCV clearance and liver disease progression. He
has special clinical and research interests in viral hepatitis, and has pioneered liver immunology
research for more than a decade. Dr. Cooper trained in the U.K. and served as Assistant Professor of Medicine,
Microbiology & Immunology at UCSF and as a Research and Gastroenterology Fellow at Stanford University. He

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has an international reputation in viral hepatitis research and management, and is listed in Whos Who of Medical
Science Educators. Phone: (415) 600-1020.

Todd Frederick, MD is a board-certified gastroenterologist and transplant hepatologist with the Liver Disease
Management & Transplant Program. He currently serves as Director of Quality and Clinical Protocols and Assistant
Director of Clinical Research. Prior to this position, he was a fellow in gastroenterology/hepatology at UCSD. Dr.
Frederick completed his internal medicine residency at UCSD and received his M.D. from New York Medical
College. He has lectured on
management of advanced liver disease, viral hepatitis, artificial liver support systems and portal hypertension,
among other topics. Dr. Fredericks research interests include the pathophysiology of portal hypertension and
clinical management of complications of advanced liver disease. Phone: (415) 600-1020. Email:

Catherine T. Frenette, MD is a transplant hepatologist with California Pacific Medical Centers Liver Disease
Management & Transplant Program. In this position, she provides comprehensive evaluation and treatment for
patients with hepatitis, liver cancer and other liver diseases, both in San Francisco and outreach sites in Northern
California and Nevada. Most recently, Dr. Frenette completed a postgraduate fellowship in gastroenterology and
hepatology, with a focus on transplant hepatology at Scripps Clinic in La Jolla, Calif. She served as assistant chief
fellow from 2006-2007. Dr. Frenette completed her residency in internal medicine at Scripps Mercy Hospital in San
Diego and received her medical degree from Rush Medical College in Chicago. Dr. Frenette is board-certified in
internal medicine and gastroenterology. Phone: (415) 600-1020. Email:

Robert Gish, MD, is a hepatologist and Medical Director of the Liver Disease
Management & Transplant Program. Dr. Gish received his undergraduate training
in pharmaceutical sciences at the University of Kansas in Lawrence and his
medical degree from the University of Kansas in Kansas City. After graduation, he
completed his internship and residency in internal medicine at the University of
California, San Diego (UCSD) and a fellowship in Gastroenterology and
hepatology at the University of California, Los Angeles (UCLA). Dr. Gish is also a
Clinical Professor of Medicine at the University of Nevada in Reno and Las Vegas,
and he teaches at University of California San Francisco (UCSF) as an Associate
Clinical Professor of Medicine. He is heavily involved in community education
regarding hepatitis and has established a dozen community outreach clinics
throughout Northern California and Nevada. Dr. Gish is board-certified in internal
medicine and gastroenterology, and certified by the CAQ in transplant medicine. Phone: (415) 600-1020.

Raphael B. Merriman, MD is a hepatologist with

the Liver Disease Management & Transplant Program. He also directs the Fatty Liver Disease Clinic which
provides state-of-the-art diagnosis and management of this disorder and access to clinical research studies.
Previously, Dr. Merriman served as Assistant Professor of Medicine at UCSFs Division of Gastroenterology. Dr.
Merriman completed fellowships in hepatology and gastroenterology at the Divisions of Gastroenterology at UCSF
and Washington University School of Medicine (St. Louis), respectively. He completed his residency in internal
medicine and also served as a chief resident at Washington University. Dr. Merriman earned his medical degree at
University College Dublin, Ireland and completed a residency in Internal Medicine at Trinity College, Dublin. He is
board-certified in gastroenterology and holds a certificate of added qualification in transplant hepatology with the
ABIM. Phone: (415) 600-1020.

Adil (Ed) Wakil, MD, is a hepatologist and Associate Medical Director of California Pacific's Liver Disease
Management & Transplant Program, where he is involved in a number of clinical trials regarding the treatment of
viral hepatitis. Dr. Wakil began his medical training at the University of Texas Southwestern Medical Center in
Dallas and performed his gastroenterology fellowship at the University of California San Francisco. He remained on
faculty at UCSF as an attending physician on the liver transplant service and pursued research interests in basic
immunology. Currently, Dr. Wakil's research interests include protocols for treating underserved urban hepatitis C
and HIV/HCV co-infected patients. Dr. Wakil is board-certified in gastroenterology and internal medicine, and

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speaks Spanish and French. Phone: (415) 600-1020.

Assad Hassoun, M.D., FACS is Surgical Director of the Kidney-Pancreas Transplant Program and performs
kidney, pancreas and liver transplants. Previously, he was Director of the Pancreas Transplant Program at Scripps
Clinic-Green Hospital in La Jolla, Calif. He also served as Clinical Instructor of Surgery at University of Minnesota
Hospital. Dr. Hassoun received his M.D. from University of Mosul Medical College in Iraq. Phone: 415-100-1010

Garrett Hisatake, M.D., FACS is a transplant and hepatobiliary surgeon in the

Liver Disease Management & Transplant Program. Previously, Dr. Hisatake
served as Clinical Instructor of Surgery and Transplantation at UCLA Medical
Center. He received his medical training at the University of Utah and the
University of Rochester/Strong Memorial Hospital. Dr. Hisatake is board-certified
in surgery. His clinical interests include liver transplantation, hepatobiliary
diseases, hepatocellular carcinoma (liver cancer), and minimally invasive surgery
for liver and complex GI diseases. Phone: 415-600-1010

Harish Mahanty, M.D., FACS joined the staff at

California Pacific Medical Center in 2005
following a transplantation surgery fellowship at
UCSF. Dr. Mahanty received his medical degree
from UCLAs School of Medicine and is boardcertified in general surgery. He has published
several research papers on transplant and organ
donation topics and performs liver, kidney and
pancreas transplantation. Phone: 415-600-1010

Robert Osorio,
M.D., FACS is
Chairman of the
Barry S. Levin,
M.D. Department
and Surgical
Director of the
Liver Disease
Management &
Program. He
performs liver transplants and hepatobiliary surgery. Dr. Osorio also serves on the board of California Transplant Donor Network (CTDN), the organ
procurement organization for Northern and Central California and Northern Nevada. Dr. Osorios research interests include artificial liver support
systems. He received his training at UCSF and is a board-certified general surgeon. Dr. Osorio is bilingual in Spanish. Phone: 415-600-1010

John Rabkin, M.D., FACS is a liver transplant and pancreaticobiliary surgeon as well as a bariatric surgeon at
California Pacific Medical Center. Dr. Rabkin previously served as Chief of Liver & Pancreas Transplantation at
Oregon Health and Sciences University (OHSU) Hospital where he was Associate Professor of Surgery at OHSU
School of Medicine. Dr. Rabkin serves on multiple editorial review boards and has published extensively on liver
transplant-related topics. Dr. Rabkin received his medical degree at Boston University School of Medicine and
postgraduate training at UCSF and University of Minnesota, Minneapolis. Phone: 415-600-1010
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