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1. In what form do proteins cross the mitochondrial membranes?

A. Bound to an importin protein via a signal sequence.


B. In fully folded form.
C. In unfolded extended form attached to Hsp 70 chaperones.
D. In unfolded extended form without chaperones.
2. Which out of the following statements is NOT true about aerobic
glycolysis?
A. phosphofructokinase converts fructose6 phosphate to fructose1, 6
bisphosphate
B. The pathway is inhibited by fructose2, 6 bisphosphate and AMP
C. The pathway takes place in mitochondria of every cell
D. The pathway produces Pyruvate and NADH
3. The first step in the glycolytic pathway in Liver
A. Is catalyzed by glucokinase
B. Uses ATP and glucose as substrates
C. Produces glucose6phosphate and ADP
D. All of the above
4. A high concentration of Glucose6P is inhibitory to which of the following
enzymes?
A. Hexokinase
B. Glucokinase
C. PFK1
D. All of the above
5. The term anaerobic means
A. without bacteria.
B. with O2.
C. without ATP.
D. without O2
6. How do cells capture the energy released by cellular respiration?
A. They store it in molecules of carbon dioxide.
B. They produce glucose.
C. The energy is coupled to oxygen.
D. None of the choices are correct.
7. Which one of the following is true?
A. Cellular respiration occurs in cytoplasm-mitochondria and in chloroplasts.
B. Photosynthesis occurs in chloroplasts and cellular respiration occurs in cytoplasmmitochondria.
C. Photosynthesis occurs in cytoplasm-mitochondria and in chloroplasts.
D. Photosynthesis occurs in cytoplasm-mitochondria and cellular respiration occurs in
chloroplasts.
8. Respiration _____, and cellular respiration ______.
A. uses glucose . . . produces glucose
B. produces glucose . . . produces oxygen
C. is gas exchange . . . produces ATP
D. produces ATP . . . is gas exchange
9. Which of the following are products of cellular respiration?
A. energy to make ATP and carbon dioxide
B. ATP and carbon dioxide
C. oxygen and energy to make ATP
D. oxgyen and carbon dioxide
10. Which one of the following statements is false?
A. Cellular respiration produces carbon dioxide.
B. Cellular respiration is a single chemical reaction with just one step.
C. Cellular respiration releases heat.
D. Cellular respiration consumes glucose.
11. The overall equation for the aerobic cellular respiration of glucose is
A. CO2 + H2O C6H12O6 + O2 + ATP + Heat
B. C6H12O6 + O2 CO2 + H2O + ATP + Heat

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C. C6H12O6 Lactic acid + ATP + Heat


D. C6H12O6 CO2 + Ethyl alcohol + ATP + Heat
During cellular respiration, the energy in glucose
A. is used to manufacture glucose.
B. is used to make ATP
C. becomes stored in molecules of ammonia.
D. makes carbon dioxide
During redox reactions
A. a substance that gains electrons is said to be oxidized.
B. electrons are lost from one substance and added to another substance.
C. the loss of electrons from one substance is called reduction.
D. protons from one molecule replace the electrons lost from another molecule.
Oxidation is the __________, and reduction is the __________.
A. gain of electrons . . . loss of electrons
B. loss of electrons . . . gain of electrons
C. gain of protons . . . loss of protons
D. gain of oxygen . . . loss of oxygen
In biological systems, an important enzyme involved in the regulation of redox reactions is
A. oxygen.
B. dehydrogenase.
C. ATP.
D. glucose.
During cellular respiration, NADH
A. is chemically converted into ATP.
B. is converted to NAD+ by an enzyme called dehydrogenase.
C. is reduced to form NAD+.
D. delivers its electron load to the first electron carrier molecule.
During cellular respiration, electrons move through a series of electron-carrier molecules.
Which of the following is a TRUE statement about this process?
A. Molecular oxygen is eventually oxidized by the electrons to form water.
B. Electrons move from carriers that have more affinity for them to carriers that have less
affinity for them.
C. Electrons release large amounts of energy each time they are transferred from one
carrier to another.
D. None of the statements are true.
Which one of the following is the correct sequence of stages in cellular respiration?
A. glycolysis, oxidative phosphorylation, and the citric acid cycle
B. glycolysis, the citric acid cycle, and oxidative phosphorylation
C. the citric acid cycle, oxidative phosphorylation, and glycolysis
D. oxidative phosphorylation, the citric acid cycle, and glycolysis
A drug is tested in the laboratory and is found to create holes in both mitochondrial
membranes. Scientists suspect that the drug will be harmful to human cells because it will
inhibit
A. glycolysis.
B. the citric acid cycle.
C. oxidative phosphorylation.
D. the citric acid cycle and oxidative phosphorylation.

17) During which phase of cellular respiration does substrate-level phosphorylation take place?
A) the citric acid cycle
B) "grooming" of pyruvic acid
C) glycolysis
D) oxidative phosphorylation
E) glycolysis and the citric acid cycle
18) Which one of the following metabolic pathways is common in aerobic and anaerobic organisms?
A) oxidative phosphorylation
B) chemiosmosis
C) glycolysis
D) the citric acid cycle

E) None of the choices are correct.


19) Which of the following is a result of glycolysis?
A) a net loss of two ATPs per glucose molecule
B) conversion of FAD to FADH2
C) conversion of glucose to two three-carbon compounds
D) production of CO2
E) conversion of NADH to NAD+
20) Glycolysis
A) does not occur in bacterial cells.
B) takes place in virtually all cells.
C) does not occur in yeast cells.
D) does not occur in animal cells.
E) does not occur in plant cells.
21) Pyruvate
A) is the molecule that starts the citric acid cycle.
B) is the end product of oxidative phosphorylation.
C) is a six-carbon molecule.
D) is the end product of chemiosmosis.
E) forms at the end of glycolysis.
22) Between glycolysis and the citric acid cycle,
A) pyruvate is oxidized while a molecule of NAD+ is reduced to NADH.
B) coenzyme A is cleaved off of the four-carbon compound.
C) a carbon atom is added to make a four-carbon compound.
D) More than one of the choices is correct.
E) None of the choices are correct.
23) During cellular respiration, glucose is converted into two pyruvic acid molecules. These molecules
A) together contain less chemical energy than was found in the original glucose molecule.
B) are oxidized.
C) each lose a carbon atom, which is released as CO 2) ) .
D) are each converted into a two-carbon molecule joined to a coenzyme A molecule.
E) All of the choices are correct.
24) The end products of the citric acid cycle include all of the following except
A) CO2.
B) NADH.
C) pyruvic acid.
D) FADH2.
E) ATP.
25) At the end of the citric acid cycle, most of the energy remaining from the original glucose is stored
in A) FADH2
B) CO2.
C) pyruvic acid.
D) ATP.
E) NADH.
26) In the electron transport chain, the final electron acceptor is
A) a molecule of water.
B) a molecule of carbon dioxide.
C) ATP.
D) ADP.
E) an oxygen atom.
27) Rotenone is a poison commonly added to insecticides. Insects exposed to rotenone will die
because

A) high levels of fermentation products will build up.


B) water will not be produced and dehydration will occur.
C) anaerobic respiration can't occur.
D) of inadequate ATP production.
E) None of the choices are correct.
28) Cyanide differs from dinitrophenol because cyanide
A) is an electron transport blocker and dinitrophenol is a reaction uncoupler.
B) makes the membrane of mitochondria leaky to H+ ions and prevents a concentration gradient from
building up; dinitrophenol blocks the passage of electrons through electron carriers.
C) inhibits the production of ATP by inhibiting ATP synthase; dinitrophenol causes mitochondrial
membranes to become less permeable to H+ ions.
D) is highly toxic to human cells and dinitrophenol is nontoxic.
E) None of the choices are correct.
29) Which of the following statements about the energy yield of aerobic respiration is false?
A) Most of the ATP derived during aerobic respiration results from oxidative phosphorylation.
B) Oxidative phosphorylation resulting from one glucose molecule may yield 32-34 ATP molecules.
C) Less than 50% of the chemical energy available in glucose is converted to ATP energy.
D) Glycolysis and the "grooming" of pyruvate together produce more NADH per glucose molecule
than does the citric acid cycle.
E) Each FADH2 molecule yields 2 ATP molecules and each NADH molecule generates 3 ATP
molecules.
30) The energy yield from the complete aerobic breakdown of a single molecule of glucose
A) is less than the yield from anaerobic respiration.
B) increases as the supply of oxygen increases.
C) is always 38 ATP.
D) can vary with the mechanism used to shuttle NADH electrons into the mitochondrion.
E) is equivalent to the yield from alcoholic fermentation.
31) During chemiosmosis
A) a concentration gradient is generated when large numbers of H+ ions are passively transported
from the matrix of the mitochondrion to the mitochondrion's intermembrane space.
B) energy is generated by coupling exergonic reactions with other exergonic reactions.
C) ATP is synthesized when H+ ions move through a protein port provided by ATP synthase.
D) H+ ions serve as the final electron acceptor.
E) energy is released as H+ ions move freely across mitochondrial membranes.
32) Which of the following processes produces the most ATP per molecule of glucose oxidized?
A) aerobic respiration
B) alcoholic fermentation
C) lactic acid fermentation
D) anaerobic respiration
E) All produce approximately the same amount of ATP per molecule of glucose.
33) Muscle soreness associated with strenuous exercise is at least partly due to
A) the presence of lactic acid produced during fermentation in muscle cells.
B) the large amount of carbon dioxide that builds up in the muscle.
C) the accumulation of alcohol from anaerobic respiration.
D) an excess of ATP that builds up during vigorous exercise.
E) None of the choices are correct.
34) In yeast cells,
A) alcohol is produced after glycolysis.
B) glucose is produced during photosynthesis.
C) lactic acid is produced during glycolysis.
D) alcohol is produced during the citric acid cycle.
E) lactic acid is produced during anaerobic respiration.

35) When proteins are used as a source of energy for the body, the proteins
A) are hydrolyzed to fatty acids and converted to acetyl CoA, which enters the citric acid cycle.
B) are converted mainly into intermediates of glycolysis or the citric acid cycle.
C) are hydrolyzed to glycerols and then converted to glyceraldehyde 3-phosphate, which is fed into
glycolysis.
D) are hydrolyzed to their constituent amino acids; electrons are stripped from the amino acids and
passed to the electron transport chain.
E) are converted into glucose molecules, which are fed into glycolysis.
36) When a fatty acid is used for aerobic respiration, it first hydrolyzes fats to
A) glycerol and fatty acids.
B) sugars and glycerol.
C) glycerol and amino acids.
D) sugars and amino acids.
E) fatty acids and sugars.
37) The conversion of CO2 and H2O into organic compounds using energy from light is called
A) photorespiration.
B) glycolysis.
C) photosynthesis.
D) fermentation.
E) cellular respiration.
38) By-products of cellular respiration include
A) carbon dioxide and water.
B) carbon dioxide and ATP.
C) oxygen and heat.
D) NADH and ATP.
E) FADH2 and NADH.
39) The summary equation for photosynthesis is
A) CO2 + H2O C6H12O6 + O2 + ATP + Heat
B) C6H12O6 + O2 CO2 + H2O + ATP + Heat
C) CO2 + H2O C6H12O6 + O2
D) C6H12O6 CO2 + Ethyl alcohol + ATP + Heat
40) Which one of the following statements is false?
A) Burning fossil fuels releases carbon dioxide that was removed from the atmosphere millions of
years ago.
B) Willows pack more fuel and power than most native trees.
C) Plants require carbon dioxide, water, and sunlight to make glucose.
D) All of the food for people can be traced back to photosynthetic plants.
E) Burning wood contributes more to acid rain than burning fossil fuels.