Human Exposure Analysis (Biomonitoring)

Why Do Human Biomonitoring?

The goal of Human Biomonitoring is to help prevent environmental
disease by doing the following:
Determine which environmental chemicals actually get into
people
Measure how much exposure each person has
Assess exposure for health studies of exposed populations
Determine which population groups are at high risk for exposure
and adverse health effects
Assess the effectiveness of public health interventions to reduce
exposures
Monitor trends in exposure levels over time

Introduction
The need to assess the real health effects from exposure to chemicals
is hampered by our inadequate understanding of what chemicals
people are exposed to and to what degree these exposures might
cause short term (acute) or long term (chronic) adverse health
effects.

What is Human Biomonitoring?

Human Biomonitoring is the measurement of toxic substances in the
human body. The purpose of Human Biomonitoring is to determine
if you have been exposed to a toxic substance, how much of that
toxic substance is in your body, and whether the amount of that toxic
substance in your body is enough to cause an adverse health effect.
Toxic substances generally enter the body through one of three
routes: ingestion, inhalation, or dermal penetration.

What Can AASlab Do for You?

The amount of substance available for toxic action depends on a

number of factors. In most cases, the substance is absorbed to some
degree into the bloodstream where it is distributed throughout
the body. At this point, toxic substances have three possible fates:
they are stored, excreted, or metabolized. Most chemicals undergo
some combination of all three. Storage typically occurs in a reservoir
such as bone or adipose tissue. Excretion involves the elimination of
substances or their metabolites through urine, feces, saliva, sweat,
or exhalation. Substances that are metabolized are often chemically
altered to make excretion of the substance easier.

Parameters Analisis

AAS Laboratory is uniquely positioned to help you with a full range

of professional services from design, development, and writing
funding/grant proposals to preparing final consultative reports on
sound scientific laboratory data.
Please contact +62 21 735 5856 or email : marketing@aaslaboratory.com
for more information or to schedule a free initial consultation.

Saat ini AAS Laboratory sudah terakreditasi ISO 17025 oleh KAN,
dengan demikian KETELUSURAN data pengukuran yang dilakukan
dapat terjamin dengan baik. Selain itu, di dukung peralatan
tercanggih di kelasnya seperti GCMS, HPLC dan Atomic Absorption
Spectrophotometer dan Tenaga Ahli yang memang mempunyai
Kompetensi di Bidangnya.
Analisa Biomonitoring yang bisa di lakukan oleh AASLab :
EXPOSURE

DETERMINAN

METHODE

RECOMENDED

Logam Arsen (As)

Urine

NIOSH

BEI`s ACGIH

PARAMETER

The time (antecedent or present), duration, and intensity of exposure

to a particular substance will dictate the choice of human tissue
that is sampled to monitor the substance or its metabolites. Most
Human Biomonitoring involves sampling humans for whole blood or
serum and urine. However, meaningful results have been achieved
from sampling saliva, feces, hair, nails, teeth, breath, and sweat. For
example, when exposed to lead from paint, approximately 90 percent
of lead absorbed will be stored in the bone over time and 10 percent
is excreted, mostly through the urine, nails, and hair.

METABOLIT

ANALYSIS

VALUES

Logam Cadmium (Cd)

Darah

NIOSH

BEI`s ACGIH

Logam Crome (Cr)

Urin

NIOSH

BEI`s ACGIH

Logam Mercury (Hg)

Urin and Darah

NIOSH

BEI`s ACGIH

Logam Lead (Pb)

Darah

NIOSH

BEI`s ACGIH

Senyawaan Benzen

Urine

NIOSH

BEI`s ACGIH

Senyawaan Toluene

Urin

NIOSH

BEI`s ACGIH

Senyawaan Xyelene

Urin

NIOSH

BEI`s ACGIH

Senyawaan Acetone

Urin

NIOSH

BEI`s ACGIH

Senyawaan Metyl Etyl Ketone

Urin

NIOSH

BEI`s ACGIH