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A man with a white coat sat wordlessly at the corner, watching the computer and recording something on papers. The small room was filled with a lot of machines and apparatus. Some reagent bottles were arranged neatly on the table. The atmosphere sometimes gave a foul smell. The smell of the chemicals and the damp air were mixing together. The man at the corner stood. Carefully, he adjusted the electron microscope, hoping a pleasing result will be obtained. “It can’t be!” The man shouted. He quickly grabbed his cellphone and dialed someone. It was important for him to tell this guy. He really had to know this news. “Mael, Mael! You should know this!” said the man. His hazel eyes shone brightly. “Elric. What’s the matter, pal?” asked the guy whose name was Mael. Professor Elric fixed his white coat. He took a deep breath. He wanted to tell this good news in one, single breath. “We did it, Dr Mael! It is a success. Finally, we are able to create it. This will save the world! This will ends all the corruption. A new world is begun!” He tried to calm himself but his heart kept bursting with ecstasy. Finally, his ten years with blood and sweat were paid off. “Thank God! The time has come for us to rise again. We show to the corrupted people, who we are. Wait there, Elric. I’ll be there. Don’t do anything foolish,” said Dr Mael. He ended the call. They could not be on the line for a long time. “The soldiers might detect us. I hope everything is fine,” whispered Dr Mael to himself. He quickly grabbed his car key. “Even a single minute delay will destroy everything,” he muttered. In the laboratory, Professor Elric could not wait any longer. He kept looking his watch. “What took him so long? The soldiers may arrive any minutes now,” he whispered. His heart was beating fast. He started to sweat. The cool air-conditioner was no longer freezing him. “Stupid adrenaline! Can you give me some time to calm,” he rumbled. For a moment, he blamed which the will tyrosine be for synthesizing to the dihydroxyphenylalanine as adrenaline. Suddenly, he heard some noise coming out from the outside. “Aha…Must be Mael.”said him. He quickly went to the door and opened it. To his surprise, there was a troop of soldiers equipped with latest ammunition in front of him. (DOPA) later converted dopamine,
norepinephrine and epinephrine. Epinephrine was a neurotransmitter which also known
“Give me the thing! It is the order from the President,” one of the army said firmly, fixing his blue eyes on Professor Elric. The others were remained still aiming their machine guns towards Professor Elric. “Haha…curse you and your barbaric leader! I’ll never give you the virus. If you have it, you will never find the antivirus.” He could not hold his anger anymore. He remembered clearly how those people kill his brother and his beloved wife, Amelia. “Just because we are Naturals, doesn’t mean you, De Novo people can do anything to us!” He shouted. He knew his fate after this. He really knew it. “You are stupid, low being. Die!” “Bang…Bang…Bang” *** The year was 2070. 50 years had past since the Project N.Gen-OH was launched. N.Gen-oH stood for New Generation of Humanity was a project to produce a “new human” with improved mental and physical activities. Parent could modify their newborn’s genotype by choosing the best phenotype of their child. With all the 54,000 of human genes were successfully located, this was no longer a dream. By using a modified DNA polymerase known as DNA Pol-G, the process of replicating was improved and the process of substituting the nucleotide became more efficient. The new generation was knows as De Novo which meant ‘anew’. The De Novo people were ruled by a man who is the founder of Project N.GenoH. His name was Xanxas, Professor Xanxas. Today, he was known as President Xanxas and being respected by the De Novos. The past 30 years was a disaster. The De Novos claimed themselves as the ‘true’ human and declared war to the Naturals. Naturals were referred to a group of people who against the project. De Novo looked them as low being which should be exterminate. Nobody knew that this later brought a cold war between the Naturals and De Novo. The Naturals were suppressed by the De Novos. A war that would never ended. A war sacrificed the humanity. *** “Ring…ring….” “Argh! Stupid clock,” the boy murmured. He grabbed his blanket. The freezing room really hindered him from waking up.
“Ame! Get up! You stupid monkey! It is 8.45 am now. The class will start soon,” shouted a young girl. She really could not stand her friend’s tardiness. The room was still silent. “Don’t make me come up there! Ok, you really want this, right,” the girl giggled. She quickly placed a ball on her feet. “Feel my flying tornado ball! Go!” The girl kicked the ball swiftly and broke the window glass. The old four-storey flat was nearly collapsed. “Ouch! Who did this?” the boy cried painfully. The ball landed on his face nicely. “Haha…Serves you right!” laughed the girl. “Chrome! What are you doing? Your ball nearly makes a hole on my face,” the boy yelled. He was called as Ame. The pain on his face really angered him. However, seeing her laughter soothed his heart. Chrome was only his friend in his new life. A life that was full of corruption and suppression. “I’ll be down there. Wait for me,” said Ame. He quickly prepared himself for the class. He could not be late. If he was late, they would look down on him. “5 minutes left. We have to run. Let’s go,” said Chrome. Without a blink, she ran as fast as her could, leaving Ame on the back. “Hey, slow down! I know you are a De Novo. I can’t match your speed, you know,” Ame shouted. He nearly lost his breath. Unlike him, Chrome was a De Novo. She was blessed with high mental and physical abilities that allowed her to do what a Natural or a normal human could not do. “You just need to increase your metabolism. Haha… Force your cells to double the glycolysis. Hurry up or we will be late for our class,” she yelled to him. Luckily, they arrived just in time. “Oho, the lousy, low human being is finally here. I wonder if you can be here without a De Novo’s help,” smirked a guy. Ame tried to smile although the guy whose name was Kiyo really annoyed him. “Well, this lousy and low being is the one who beat you in the final exam,” said Ame calmly. He surely knew how to shut up the guy. Kiyo fixed his eyes on Ame. His pride was shattered. Quickly, he clenched his fist and tried to punch Ame. However, Chrome stopped him. “Stop, Kiyo! Don’t be childish! Dr. Nunnaly will arrive any minutes now,” she shouted. The class sat in stunned silence. They gave a high respect to Chrome who was one of the high communities of Student Council of the university.
Kiyo stood still and walked away. He did not want to fight her. She had the power to blacklist anyone who she disliked. Now, she was close with the Natural. “Argh! This really annoys me,” Kiyo muttered to himself. Ame approached Chrome and thanked her. She replied it with a beautiful smile on her face. “You can beat Kiyo, but I will always be the first one. Improve yourself so that you can beat me. I don’t want you to compare yourself with us. I really believe that we, both Natural and De Novo are the same. We are humans,” said her firmly. She left him and walked away to her desk. “Yes, I will prove to you. I will strive hard and shows to the people that we, Naturals are as good as the De Novos,” he whispered. He saw Dr. Nunnaly entered the lecture hall and quickly grabbed his Biochemistry notes. “Focus and success,” he said softly in his heart. “Today’s lecture really made me sleepy. It is hard to memorize all the metabolism pathways,” Chrome complained. She tried to focus but ended up by sleeping through out the lecture. “Haha, it must be some problem with your sleeping regulation. Maybe your trytophan is unable to synthesize serotonin,” Ame laughed. He unwrap the wrapper of the sandwich and pretended to know nothing. “You really irritate me,” Chrome said firmly. She looked serious. “I’m sorry, pal. Erm, for the metabolic pathways, I can teach you. But, you are a De Novo, you should not face any problems in understanding and memorizing,” he smirked. “It is useless to be a De Novo, if I dislike it. So you want to teach me. Let’s start with urea cycle,” she wanted to test her friend. As a De Novo, she could memorize the cycle within seconds. “Yes Miss! First, carbamoyl phosphate is added by ornithine carbamoyl transferase inside the mitochondria to ornithine, and citruline is created. Then, the cycle continues in cytosol. Citrulline diffuses and being condensed with aspartate to generate arginosuccinate by the aid of arginosuccinate synthase,” Ame started to explain. He really liked explaining things. “Next,” she said wanting Ame to continue.
“Arginosuccinate lyase cleaves arginosuccinate to arginine and fumarate. Fumarete enters the Kreb’s cycle. Then…hey, are you listening or not!” he yelled to Chrome who started to feel sleepy. Chrome shocked. “Your explanation is boring. Let me continue. Arginine hydrolyzes to urea and ornithine by arginase. Ornithine completes the urea cycle and return to mitochondria. The end,” she smiled. Ame looked pissed off. “Don’t ask me if you’re already knew it. Let’s go to Anatomy class. We really don’t want Prof Fir to be mad on us,” he said and quickly grabbed his PC-pack. “Hey, wait for me!” she swiftly followed Ame and went to the class together. *** The long needle stroked the number 9 on his watch. Ame walked tiredly after finishing his part-time job. The road was dark and full of stench. It was the only road that he could use during night. It was the only road that De Novos would never lie their feet on. Homeless people and kids were lying and sleeping on the road. They were Naturals who had been abandoned by the society. “The ‘me’ now can’t help you. I’m sorry. I promised you that I will change your fate, our fate and destiny” he whispered. He was one of lucky Naturals. He still had proper education although he went through too many hardships. He was raised in an orphanage since he was three. The only thing he knew that he was sent there by a doctor. He did not have any memories about his parents neither knowing their names. However, he knew that his parents were no longer present on this world. The next day was a peaceful Sunday. It was a special day for Ame. He waked up early for this day. He planned to visit the orphanage with Chrome. “You’re early today,” said Chrome. Ame smiled. They went to the orphanage by a car. The orphanage was located at the outskirts of the city, about 50 km from his place. At noon, they arrived at the location. To his surprised, there was no house with kids playing at the yard. There was no green scenery and lovely panorama of countryside. The only left there was destructions and blood. “What’s happening here?” he stunned. He was speechless. His preserved memory was destroyed. Chrome kept in silence. She really knew who was behind all of this. “De Novo,” she whispered softly.
Quickly, he drove the car and went to the nearest village. He hoped that he would found someone who could explain the situation. “They were killed because they don’t want to give the land to the De Novo,” said one of the villagers. The old man shuddered when he told the story to Ame. Ame stunned. He could not believe what he had just heard. He gritted his teeth and clenched his fist firmly. “Why they have to do that? They have to be punished!” he screamed with anger. The faces of his beloved Madam Sara, his care-giver and the kids came into his mind. “I can’t protect them,” he cried. Tears started to run on his cheeks. “Ame, maybe we can still discuss this matter with them,” Chrome said as she wanted to calm him down. Ame glared towards Chrome. “Shut up! You are one of them. You don’t know our feelings. Vanish from my sights, now!” he yelled to her. She knew that his hatred towards De Novo finally reached her. “I hope peace will comes to our life,” she said softly and walked away, leaving Ame in his wrath. *** “Ame, somebody wants to meet you,” old men said to Ame. “Who is that?” Ame asked. If the person was a De Novo, he surely killed him down. He was still mad on what just happened to him. However, he did not want to do that. He tried to calm himself. “A middle-aged man who calls himself as a doctor, Dr Mael,” the old man replied. Ame knew this man. According to Madam Sara, he was the one who sent him to the orphanage. He really wanted to meet him and asked him about his parents. “I want to meet him,” said Ame. “Hi, Ame. You’ve grown up, my son. Do you know who I am?” the doctor asked. “Yes. You’re Dr Mael. Seventeen years ago, you sent me to the orphanage. Nothing more. I’m sure you are related with my family,” said Ame calmly. He required more details from this guy. “I see. Well then, I need to introduce myself. I’m Dr Mael. Do you know who your parents are?” the doctor asked him. Ame shook his head. “Your father, Professor Elric is a great friend of mine. Your mother is Amelia. She is graceful as ever. She is the one who named you after her name. Oh, by the way, you have an uncle, Alex, but…” he paused for a while. “But all of them were no longer here, right?” Ame continued the sentence.
The doctor took a deep breath. He was aware of the thing that he would say to Ame. “Yes, all of them were killed. They were killed by the De Novo,” Dr Mael spoke softly to the young man. The fact was very bitter. All of his beloved ones were killed by De Novo. “They must be punished. “I don’t want to stay here, doing nothing,” he wept. “Yeah, that’s why I come here to give you a task,” Dr Mael said. Ame took a glance on the man’s face. His face was serious. “17 years ago, your father had a research on synthesizing a virus. This virus will end all this corruption and injustice in our world. However, your father was killed by the soldier and I was unable to do anything. The De Novos are already got the virus,” said the doctor. “So, what can I do for you?” asked Ame. The conversation had become interesting. “I want you to develop a new virus. I had some of your father’s research notes with me. I know you can do it. You have the talent and you are intelligent,” the doctor said. He tried to convince the young guy. Ame took a deep thought. It was a risky task. Besides that, he still did not finish his study. He left his study since the tragedy on the orphanage was occurred. However, this was for the sake of human race. He had to do it. This was the time for him to change their destiny. “Yes, I will.” *** “Finally, the graduation day is arriving,” Kiyo said to Chrome. She nodded. Three years had passed and now they would be graduated. Three years had also passed since her last met with Ame. “I wonder what he is doing now,” she whispered. Only God knew how much she missed him. “Come one, stop worrying on that jerk,” Kiyo started to feel irritated. He quickly surfed the Internet to find any interesting news. Suddenly, a dialogue box popped up on the screen. An audio was played on the box. “Today is a happy day. Time has come to celebrate it. Two hours from now, the ceremony will be started.” “What the heck is this? Maybe, it’s just an advertisement about our graduation day,” Kiyo said. He did not want to feel anxious about this small matter.
Chrome looked on the screen. The thing that they heard just now, what was the true meaning behind the ceremony? “I need to go. See you on the graduation ceremony,” she said and left the room. *** At the corner of the outskirt of the city, there was a small building. The building was known as Laboratory 9. “How is the preparation?” asked a guy with long white coat. “All are ready, sir. The virus and the bombs are already prepared,” a big guy replied him. The guy with long white coat smiled. “How about the Naturals? Have you placed them in the protected area?” asked the guy again. He wanted a confirmation about the matter. “They were on their way to the area. The De Novos do not suspect anything. Maybe, they feel better if all of us are vanished from their territory. Ah, we will give them the antivirus, as soon as they arrive there, sir,” another guy replied him. The guy with long white coat felt relief. He did not want to involve the innocent people. “Congratulations Ame! Finally, you successfully create the virus. You are as great as your father. Ah, you might be greater than him!” Dr Mael complimented him. Ame smiled and fixed his white coat. Three years had passed since he began his research. Finally, he successfully created a virus. It would end all the corruption in this world. “’Bloody Sweet” will end it,” Ame said with a smile on his face. “Sir, can you explain to us what is actually ‘Bloody Sweet,” his men asked. They really wanted to know what the virus can do to the De Novo. “’Bloody Sweet’ is a virus that will alter Pentose Phosphate pathway in the erythrocytes. The virus will invade the erythrocytes and causes Glucose-6-phosphate dehydrogenase to become deficient and later it will be ceased. NADP+ will unable to be reduced to NADPH. This prevents glutathione to be in its reduced state,” he explained the principle of the virus to his men. “As we all do know, reduced glutathione is important to maintain hemoglobin in the reduced Ferrous state which is necessary for oxygen binding. Besides that, it is vital in inactivating organic peroxidase via the action of Glutathione peroxidase enzyme. The peroxidase is harmful as it can produce free radicals,” Dr Mael continued.
Ame nodded. He would never think to use the pathway if there were no guidance from Dr Mael and his father’s notes. “How this event will affect them?” asked one of the men. “Well, if the reduced glutathione is inactivated, the hemoglobin can’t maintain its Ferrous state and its ability to bind oxygen will be destructed. Other than that, the free radicals will destroy the integrity of the cell. Although De Novos are special, they will never survive if there is an extreme reduction and failure of oxygen utilization in their body,” he replied. The virus would disperse through the air and the it would multiply within seconds. ”Hurry, we must take the antivirus first,” the doctor said to the crowd. Ame nodded. Luckily, both of them had successful developed the antivirus “Yes. The time is 7 am. There are only two hours left. We need to prepare for the ceremony. Jack, you will go to the main government building. Anita and Julia, both of you will go to the airport. Danny will take the public transport. Verde, you go to the water plant and I will go to the University of N.Gen-OH. Do you understand?” Ame requested a confirmation answer from his subordinates. “Yes sir! We clearly understand” all of them replied. After that, they went to their respective area to begin the ‘ceremony’. *** “I want to meet grandfather,” Chrome said to the secretary. She needed a confirmation from him. “But Miss Chrome, Mr. President is busy right now,” the secretary replied. She cannot let the young lady to enter the meeting room. “What makes you come here, Miss Chrome,” a rough voice broke their conversation. A 75 years old man walked slowly to the lady. “Grandpa, we need to talk,” Chrome said firmly. She looked serious. “If it is regarding to the next two hours ceremony, you don’t need to worry. Our soldiers are already making their move. We will kill all the suspected Naturals who still remained here,” the old man said proudly. She really hated the idea. It was the worst idea ever. “Grandpa, please don’t do anything recklessly. I will negotiate to them,” she told her idea to the President. “What power that you have? Please don’t make a joke here,” President Xanxas laughed. He could not understand her granddaughter’s idea and principles.
She clenched her first tightly. “I’ve the power, as the future president of this country. Grandpa, bear in your mind that you are still a Natural although you are the founder of the project,” Chrome stared deeply on his heartless grandfather. The old man stood in silence. She left the room and walked away. “Well, for this time, I’ll see your ability,” President Xanxas whispered to himself. *** The university was full with people. The atmosphere was very pleasing with the surrounding was decorated nicely. Today was Graduation or Convocation Day in University of N.Gen-OH. From the crowd, there was a young man with a black coat, holding a small briefcase on his left hand. On the right hand, he held a bouquet of white roses, for someone who was very dear to him. “It has been three years. Nothing is changed,” Ame said. He quickly made his way to the Central Hall. He took a glance of his watch. “30 minutes,” he said softly. The hall was already full with people and students. All of them were waiting for the ceremony to start. Ame sat on a chair at the corner. He did not want to be a center of attention. Any minutes from now, he would leave the briefcase and the bomb with the virus will be activated. He did not want to feel sorry. De Novos had done too many bad things to them. However, he wanted to do something. He wanted to take Chrome with him. 5 minutes left and the bomb was placed at a place that people would never expect. The timer had started. Suddenly, he saw a lady entering the hall. She was Chrome. He had to meet her. “Chrome,” he whispered softly. “Ame, what are you doing here?” Chrome asked but no reply from him. He quickly pulled her to the back of the hall. “Chrome, please come with me and you’ll be safe,” he said softly. He needed answer from her. She fixed her aqua eyes on his hazel eyes. “What do you mean? Don’t tell me you’re involved with the ‘ceremony’,” she asked. She hoped a negative answer from him. “Yes and nothing can be done anymore. The timer is already started. The bomb was filled with deadly virus. 5 minutes from now, the De Novo will vanish from this world. But, I want you to be safe. You are important to me. Please come with me,” he said firmly. He had to tell the truth. He did not want to hide anything more from her.
“What do you say? No, this is not the right way. I know we can still discuss this matter. Please don’t do anything reckless,” she believed on him. He was not a bad guy. He was sensible. She knew him. “I’m sorry but we have suffered so much because of your people. This is the time to end it,” he grasped his principle. Construction could only be done after destruction. For this case, they had to destroy these proclaimed “true human” so that a new peaceful world could be created.. “You’re wrong. Do you still remember what I used to tell you? Both of us are humans. We are the same. I promise you. We still can change this situation,” she determined with her idea. “How? Please don’t say nonsense!” he was tired of listening her. The time was around the corner and he had to take her away from there. “I am the granddaughter of President Xanxas and I’ll be the next in the line for the position. We can work together, both Natural and De Novo. We will make a peace world for us. We don’t want to lose our beloved ones anymore. I’ll prove to you,” she showed her resolve. She wanted to change everything but not with violence. “I don’t want you to be just like them who had taken your beloved ones,” she continued. Ame stood still in silence. He aware that he had chosen a wicked path. A path made him to be on the same level with the corrupted De Novo. “You have a sweet mouth, the sweetness that melts my heart and my principle. You are the worst enemy ever,” Ame smiled to her. He knew he had lost. He believed in her and what she had said to him, three years ago. He quickly grabbed his cell and dialed his subordinates. “Stop the timer. Our mission has failed.” “Are you sure, sir,” Jack asked. He did not want to be confused. “Yes. Peace will eventually come to our hand,” Ame replied. He hoped that his men could understand him. “But, sir…,” Julia felt uncertained. “The soldiers had surrounded the buildings and we could not escape from here,” she continued. “I’m President Xanxas’ granddaughter and the future President of this country. My name is Chrome. I’ll ensure your safety,” Chrome reassured them. “Yes sir! We will obey you and your resolution,” all of them were confirmed with it. The timer was stopped and the bombs were not exploded. Their safety was guaranteed. ***
The date was 13th September 2075. A pact was signed between President of De Novo, Miss Chrome and the leader of Natural, Mr. Ame Elric. The Pact of Equality and Peace would bring peace, serenity, freedom and harmony to the humanity. A world of justice had just begun. -THE END-