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Hemophilia

Haemophilia, also known as hemophilia, was first discovered in the
ancient times by the Jews. The Talmud, Jewish writings, stated that if two
male babies had died from minor bleeding already, male babies afterwards
do not have to be circumcised. In the tenth century, an Arab Physician,
Albucasis, wrote about a family who died from a minor injury. Dr. John Conrad
Otto discovered that hemophilia was hereditary and affected males.
Although there were several accounts of hemophilia, the name hemophilia,
which came from Greek, first appeared in 1828 by Hopff. Hemophilia was
made a royal disorder when Queen Victoria of England had a son who has
hemophilia. That jeopardizes the whole royal bloodline and the prince
diagnosed with hemophilia was kept a secret.
Hemophilia is a bleeding disorder that slows blood clotting process.
People with hemophilia can experience bleeding following an injury, or even
having a tooth pulled out. Hemophilia can cause serious bleeding into the
joints, muscles, brains, or other internal organs. There are two main types of
hemophilia, hemophilia A and hemophilia B. Hemophilia A Is cause by a
change in the F8 gene while hemophilia B is caused by a change in the F9
gene. Both genes are responsible for creating coagulation factors, which are
proteins that work together in the blood clotting process. Hemophilia A and
hemophilia B are recessive sex-linked disorders, meaning they are passed
through the sex chromosome, X. However, since hemophilia is a sex-linked
trait and males only have one X chromosome, males are more likely to
inherit hemophilia. Females can be either have hemophilia or be a carrier,
someone who carries a gene for a disorder.
Symptoms for hemophilia may vary depending on the level of clotting.
However, a person who has sudden pain and excessive bleeding from an
injury, definitely have hemophilia. Unknown nosebleeds or spontaneous
bleeding is definitely a sign of hemophilia. Because hemophilia is a disorder
that slows blood clotting, and forms of intense bleeding from minor injuries is
a sign that hemophilia might be present. There a multiple signs of
hemophilia which include pain, swelling in joints, and unusual bleeding after
vaccinations, painful headache, neck pain, and double vision. Hemophilia can
cause damage to joints, the internal bleeding can put pressure on joints
causing pain. Moreover, Bleeding internally can cause limbs to swell causing
possibly numbness or pain. Likewise, People with hemophilia tend to get

The life expectancy of someone with hemophilia varies depending on the kind of treatments. clotting factors were beginning to be available. Their goals are to implement prevention programs to improve quality of life. That will put the following generations in danger too. it could only mean that their mom was a carrier which puts the family in danger of other members having hemophilia.blood transfusions increasing their risk of receiving contaminated blood products. A person diagnosed with hemophilia can affect the whole generations following. hemophiliacs were treated with fresh blood: nonetheless. People with severe hemophilia died. Likewise. mostly from bleeding in vital organs. Later in the 1960s and 1970s. The CDC is currently researching hemophilia. The CDC studies inhibitor. an antibody that people with hemophilia develop . there are not enough clotting factors to stop serious bleedings. Usually. in childhood or early adulthood. someone with hemophilia will have a life expectancy 10 years less than someone without hemophilia. and regular infusions of DDAVP or clotting factor. One person in a family that has hemophilia can change the course of a whole family. If someone from the family has hemophilia. bleeding may stop with an infusion of recombinant clotting factor or clotting factor from donated human blood. nevertheless. they conduct research to learn more about the bleeding disorders and factor for complications. there are therapies that stop bleeding and ongoing treatments for severe hemophilia. Physical therapy is another option. For someone with a moderate or severe hemophilia A or hemophilia B. Person with mild hemophilia A can have a slow injection of the hormone desmopressin (DDAVP) which will simulate a release of clotting factors to stop bleeding. In the 1950s and 1960s. Today. Fibrin sealants are medications applied directly to wounded areas to promote clotting and healing. deliver health promotion messages to help people make decision about their health and to identify new treatments and hopefully a cure for hemophilia. someone diagnosed with hemophilia lives a normal life. Some examples of ongoing treatments are clot-preserving medications (antifibrinolytics). It can ease signs and symptoms if bleeding has damaged the joints. Therapies for bleeding episodes are based on the type of hemophilia. fibrin sealants. Hemophilia can affect the entire family as well as the person who has it. Concentrates are freeze-dried and can be kept at home and used when needed. Clot-preserving medications help prevent clots from breaking down. design interventions that will help prevent complications.

p." What Is the Life Expectancy of Someone with Haemophilia? N. 05 Feb. hemophilia was not present in the early ancestors therefore led to a mystery for everyone...  "National Haemophilia Council. Spontaneous mutations are about 30% of all hemophilia cases..  "Hemophilia. was a hemophiliac. n. n.d. Queen Victoria’s youngest son.p. 2015. Web.. 04 Feb. N. 2015.  "Hemophilia. 06 Feb. Citations:  "The History of Hemophilia. Web. Web. N. N. 05 Feb. 2015.d. . Alice and Beatrice was carriers and their descendants had hemophilia. Web.Canadian Hemophilia Society. Leopold. This could lead to a better understanding of the causes of the inhibitor and help to prevent them. Web. 07 Feb. It was said that the hemophilia in the royal family came from spontaneous mutations.. n. 2015.d.  "Hemophilia.that could increase risk of joint disease." ." Complications. 2015.Canadian Hemophilia Society.p. However.  "Hemophilia.d.p." . Web. 04 Feb.d." Treatments and Drugs." Genetics Home Reference. This hemophilia that infected the royal family will forever remain a mystery. Although the royal bloodline of hemophilia is unknown. Prince Leopold is the only kid in the royal family to have hemophilia. N.d.p. Neither her dad nor her mom had hemophilia or was a carrier.d.p. N.p. n.. Charlotte Zeepvat came up with a theory that there were unrecognized hemophiliacs in the ancestors of Queen Victoria’s mother. n. 2015.  "The History of Hemophilia." Symptoms. n. Web.. 04 Feb. N. n. 2015.

09 May 2013. 09 Feb. n.p. 09 Feb." Unofficial Royalty. "Why We Do Research on Hemophilia.  "Royal Hemophilia Carriers. Centers for Disease Control and Prevention. 2015. . Web..d. 2015. N." Centers for Disease Control and Prevention. Web.