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BACTIGRAS

Total Antiseptic Dressing

Overview

Structural formula
Molecular Formula : C 26H 38C1 2N 10O 4
Molecular Weight: 625.6
Chemical Name : 1,6-di (N-p-chlorophenyldiguanidino) hexane diacetate

Description
Chlorhexidine acetate is a white to pale cream microcrystalline powder, odourless or almost
odourless. It is soluble (at 20C) in 55 parts of water and 15 parts of alcohol.
Composition of Dressing : Chlorhexidine Acetate BP 0.5% in white soft paraffin BP.

Action
The action of chlorhexidine acetate is both bacteriostatic and bactericidal. Chlorhexidine Acetate has
been shown to be active, in vitro, against a wide range of Gram-positive and Gram-negative bacteria
at concentrations of 10-50 g/ml. These include: B. subtilis Sal. pullorum Strep. lactis V. choleroe
Strep. pyogenes (4 strains) Strep. faecalis Coryn. diphtheriae Sal. dublin Strep. pneumoniae Sal.
typhimurium Staph. aureus (20 strains) A. aerogenes Pr. vulgaris E. coli P. aeruginosa (10 strains)
Chlorhexidine has been found to be ineffective against heat resistant spores and acid-fast bacilli.

Indications

BACTIGRAS is indicated for adjunctive treatment and prevention of infection in skin loss lesions,
including wounds, burns and ulcers.

Contraindications
BACTIGRAS is contraindicated in patients with a known, or suspected, sensitivity to chlorhexidine.
Due to the cationic properties of chlorhexidine, BACTIGRAS is incompatible with anionic surfactants
and other anionic compounds. One layer of tulle gras only should be applied directly to the surface
of lesions being treated, and this should be done with forceps under sterile conditions. Avoid contact
with eyes, the middle ear, meninges and brain.

Precautions
BACTIGRAS should not be used if the seal or wrapper is broken. Photosensitivity, hypersensitivity
and contact eczema have been observed, but the incidence has been very low. Since its introduction
on the market in the U.K., reports indicate that the tulle presentation of chlorhexidine acetate causes
only slight skin irritation or sensitization and that there is no pain on application. As a topical
preparation, there have been no reports of chlorhexidine acetate overdosage by a systemic route.
Accidental systemic administration of chlorhexidine solutions has failed to yield any specific ill
effects, which were attributed to chlorhexidine. Gastric lavage is indicated for acute ingestion of
chlorhexidine solutions.
BACTIGRAS dressing is for administration to adults and children; it may be changed daily but
frequency of application will depend upon the clinical circumstances (average: every 2-4 days). It is
intended that the dressing will be principally used on up to 15% body area wounds for adults, (10%
body area wounds for children). Although there is insufficient evidence to establish the safety of
more extensive use, such use on larger area wounds may be considered when in the opinion of the
physician, the expected benefit outweighs the potential risks. (Reports indicate that chlorhexidine
acetate 0.1% solutions have been used on body area wounds of up to 50% without ill effect). The
dressing is to be applied directly to the wound surface, one layer only, with forceps, under sterile
conditions. Duration of administration will range from a few days to several months in extreme
cases, depending upon the nature and severity of the wound. Treatment should be continued until
satisfactory healing has occurred or until the wound site is ready for grafting. The drug should not be
withdrawn from the therapeutic regimen while there remains the possibility of infection unless overt
infection occurs, requiring specific alternative therapy, or a significant adverse reaction occurs.
BACTIGRAS should be stored flat under controlled room temperature ( < 25C).

Overview

Description
JELONET is a paraffin gauze dressing

Features

Soft paraffin base

Sterile leno weave presentation

Comprehensive size range

Benefits
Soothes and protects the wound and allows free passage
of viscous exudate
JELONET is soothing and low-adherent and allows the wound
to drain freely into an absorbent secondary dressing.
Maintains shape, resists fraying
JELONET is a sterile paraffin tulle gras dressing made from
open weave gauze. The gauze has interlocking threads which
minimise fraying when the dressing is cut to shape.
Can be combined with topical medication of choice
JELONET is not medicated and so is ideal for use with the
topical antiseptic or antibiotic of choice.

Indications

Minor burns and scalds

Donor and recipient graft sites

Skin loss wounds, lacerations and abrasions

Leg ulcers

What is Tempograft

Tempograft is the brand of Collagen Sheet derived as Temporarily Grafting, for the raw
areas of the skin and Burn Wound Management, preserving in Isopropyl Alcohol as sterile
medium and sterilized by Gamma Irradiation which is the best and well accepted sterilization
across the globe.

Tempograft is very useful in treating Burns especially in Superficial and Partial thickness
Superficial Burns.

Tempograft will firmly adhere to the raw areas and when epithelialization occurs, it peels
off on its own.

Therefore no need of repeated dressings, hence it is convenient to the surgeon and


comfort to the patient.

Tempograft will reduce the usage of IV fluids, Albumins and Antibiotics.

Tempograft will give symptomatic Pain relief and allows faster epithelialization.

Tempograft will reduce the hospital stay.

In total Tempograft is most cost effective treatment in Burns & Wounds.

Indications for Tempograft

Superficial & Partial Thickness Superficial non-infected Burns.

Third Degree Burns as a temporary skin cover after escharectomy /tangential excision.

Skin Donor Sites.

Traumatic Loss of Skin.

Chronic Skin Ulcers.

Shallow Pressure Sores.

Dermabrasions.

Applications of Tempograft:

Denuded areas should be thoroughly cleaned for external contamination. Infected wound
should be thoroughly debrided.

Select the right dimension of Tempograft Sheet for application.

Take out the Tempograft Sheet from the aluminum pouch by tearing open at the neck area.

Tempograft Sheet should be thoroughly washed with sterile normal saline in a


sterile tray.

Apply Tempograft Sheet firmly on the raw area and ensure that the air bubbles are
removed for an effective adhesion.

Tempograft Sheet promotes healthy granulation in deep wounds (e.g. 3rd degree burns)
for early grafting.

Repeat dressings not required unless Tempograft is rejected due to underlying pus or
complication. For chronic skin ulcers- 2 to 3 applications of Tempograft in the intervals of about 4
days after a thorough debridement each time, enhances healing.

Precautions & Warnings:

Grossly infected wounds may reject Tempograft Sheet


Avoid in patients hypersensitive to Collagen
Sterility not guaranteed if the pack is open or damage

Storage:

Tempograft pack can be stored under normal storage conditions.

Availability:

Tempograft is available in different sizes like: 5x5 cm, 10x10 cm, 10x25 cm & 15x30 cm.

What is ACTICOAT?
The ACTICOAT family consists of dressings which are
flexible, absorbent and conformable1,2 and that provide an
efficient and effective barrier to bacterial penetration3.
ACTICOAT has been shown to offer significant clinical4 and
economic5 results compared to other silver dressings.

ACTICOAT for Patients

The ACTICOAT range is proven safe in over 10 years of


clinical trials6,7,8,9. Patients benefit from a dressing that is

shown to be fast10,11,12,13 and


effective invitro against a broad spectrum of gram positive and gram
negative bacteria and fungal wound pathogens14,15 including
suberbugs such as MRSA, VRE16,17 and NDM-1
carbapenemase containing bacteria18.
In a comparative cohort study (n=75) in mixed chronic
wounds 60% of patients managed with the ACTICOAT saw
resolution of infection within 2 weeks compared to only 4%
and 8% of patients in the two alternative silver dressing
groups4.
A study in lower leg revascularisation surgery complications
(n=248) demonstrated a 64% reduction in post-operative
wound complications following a change in protocol a
conventional gauze based dressing to ACTICOAT
Absorbent19.
A meta-analysis of RCT data20 (n=285) from the burns area
shows results comparing ACTICOAT with traditional
standards of care such as decreased pain21,22, less dressing
changes23,24 and reduced complication rates25 contributing to a
shorter length of stay25.

ACTICOAT Technology

The antimicrobial properties of Silver have been exploited for


centuries31; we are now in a position where there is a deeper
understanding of the mechanism behind this protection and
how we can optimise it to benefit patients and HCPs.
The silver on ACTICOAT dressings is the unique
nanocrystalline SILCRYST silver.
Silcryst silver is created via a physical vapour deposition
process to form a nanocrystalline structure with a large
accessible surface area.

Magnification
of nanocrystalline silver
with an increased surface
area to volume ratio

Magnification of normal
silver

ACTICOAT with SILCRYST silver possesses the key


characteristics of an antimicrobial dressing:
ACTICOAT is effective: Dressings in the ACTICOAT range
have been proven, in vitro, to be effective against a broad
spectrum of over 150 wound pathogens gram positive,
gram-negative, anaerobic and resistant bacteria14, including

multiple MRSA strains14 and bacteria containing NDM-1


Carbapenemases18. It has a bactericidal effect, unlike some
other silvers which are simply bacteriostatic32,33.
ACTICOAT is rapid: Dressings in the ACTICOAT range are
proven, in vitro, to begin working within 30 minutes10,13,34,35.
This rapid action gives the bacteria very little time to multiply
and allows control to be exerted faster.
ACTICOAT is sustained: The ACTICOAT range provides an
antimicrobial barrier for the wear time for the dressing; chose
between 3 or 7 days to suit your patient. Please refer to the
instructions for use for product specific wear time.
ACTICOAT is easy to use: the ACTICOAT range of
dressings are available in a variety of forms including
ACTICOAT Flex; a conformable wound contact layer that is
suitable for use under Negative Pressure Wound
Therapy36,37,38 ACTICOAT Site specifically designed for
percutaneous device sites, ACTICOAT Moisture Control; a
foam based dressing and ACTICOAT Absorbent; a calcium
alginate dressing. This wide range of dressing types ensures
that the appropriate form can be s

Biatain Adhesive

Biatain Adhesive superior absorption for wounds that need extra adhesion

Biatain Adhesive is a soft and conformable polyurethane foam dressing with a hydrocolloid adhesive.

Product information & resources

Product description
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Product variants
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Product description
Usage
Biatain Adhesive can be used for a wide range of exuding wounds, including leg ulcers, pressure ulcers,
second-degree burns, donor sites, post-operative wounds and skin abrasions. Biatain Adhesive can be
used in combination with compression therapy.
Biatain Adhesive is a soft and conformable polyurethane foam dressing that effectively absorbs and
retains wound exudate. This ensures a moisture balance that is optimal for healing of exuding wounds.

Unique 3D foam structure for superior absorption


When in contact with exudate the unique 3D foam structure of Biatain conforms closely to the wound bed
even under compression.

Minimal maceration and leakage


The superior absorption and retention of exudate minimises risk of maceration and leakage. This
adhesive dressing is well suited for use on wounds with healthy peri-ulcer skin and in areas with a need
for extra adhesion.

Long wear time


Due to the superior absorption capacity of Biatain the dressing has a long wear time. Clinical studies have
shown a wear time up to 7 days.

Soft and flexible dressing


Biatain Adhesive is a soft and flexible dressing that is very comfortable to wear.

Mode of action
The unique 3D foam structure absorbs the exudate vertically and locks the fluid away within its structure,
still leaving the wound moist providing optimal moist wound healing conditions.

Composition
Biatain Adhesive is a soft and conformable polyurethane foam dressing with a skin friendly hydrocolloid
adhesive border.
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