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Neonatal conjunctivitis - Wikipedia, the free encyclopedia

26/04/15 04:02

Neonatal conjunctivitis
From Wikipedia, the free encyclopedia

Neonatal conjunctivitis, also
known as ophthalmia neonatorum,
is a form of conjunctivitis contracted
by newborns during delivery. The
baby's eyes are contaminated during
passage through the birth canal from
a mother infected with either
Neisseria gonorrhoeae or
Chlamydia trachomatis. Ophthalmic
ointment containing 0.5%
erythromycin is typically applied to
the newborn's eyes within 1 hour of
birth as prophylaxis against

Neonatal conjunctivitis

A newborn with gonococcal ophthalmia neonatorum.
Classification and external resources



098.40 (
icd9=098.40), 771.6

gonococcal ophthalmia.[1] If left
untreated it can cause blindness.

1 Definition

DiseasesDB 9237 (

2 Cause
2.1 Non infectious

MedlinePlus 001606

2.2 Infectious


oph/325 (


D009878 (

3 Signs and symptoms
4 Complications
5 Treatment
6 References
7 See also

Neonatal conjunctivitis by definition presents during the first month of life. It may be infectious or non
infectious.[2] In infectious conjunctivitis, the organism is transmitted from the genital tract of an infected mother
during birth or by infected hands.


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In most countries neomycin and chloramphenicol eye drops are used instead. mucoid or mucopurulent depending on the Página 2 de 4 .Neonatal conjunctivitis . the free encyclopedia 26/04/15 04:02 Non infectious Chemical irritants such as silver nitrate can cause chemical conjunctivitis. Thus. but may occur up to two weeks after delivery. Corneal involvement (rare) may occur in herpes simplex ophthalmia neonatorum. which may perforate resulting in corneal opacification and Staphyloma formation. Eyelids are usually swollen. usually lasting 2–4 days.[3] Other agents causing ophthalmia neonatorum include Herpes simplex virus (HSV 2). Infants with chlamydia pneumonitis should be treated with oral erythromycin for 10–14 days. Treatment http://en. Staphylococcus aureus. Conjunctiva shows hyperaemia and chemosis. Infectious Many different bacteria and viruses can cause conjunctivitis in the neonate. Complications Untreated cases may develop corneal ulceration. conjunctivitis secondary to infection with chlamydia (Chlamydia trachomatis) produces conjunctivitis after day three post birth.C. Babies infected with chlamydia may develop pneumonitis (chest infection) at a later stage (range 2 weeks – 19 weeks after delivery). Streptococcus pneumoniae.Wikipedia.wikipedia. Conjunctival discharge: purulent. The discharge is usually more watery in nature (mucopurulent) and less inflamed. Streptococcus haemolyticus. Time of onset depending of the cause Chemical causes: Right after delivery Neisseria gonorrhoeae: Delivery of the baby until 5 days post-birth (Early onset) Chlamydia trachomatis: 5 days post-birth to 2 weeks (Late onset . The two most feared causes are N. silver nitrate is no longer in common use. Ophthalmia neonatorum due to gonococci (Neisseria gonorrhoeae) typically manifests in the first five days post birth and is associated with marked bilateral purulent discharge and local inflammation.trachomatis has longer incubation period) Signs and symptoms Pain and tenderness in the eyeball. In contrast. gonorrheae and Chlamydia acquired from the birth canal during delivery.

the free encyclopedia 26/04/15 04:02 Prophylaxis needs antenatal. Curative treatment as a rule. conjunctival cytology samples and culture sensitivity swabs should be taken before starting treatment Chemical ophthalmia neonatorum is a self-limiting condition and does not require any treatment. every five minutes for next half an hour and then half-hourly till infection is controlled) If the cornea is involved then atropine sulphate ointment should be applied.wikipedia. QID Cefotaxime 100–150 mg/kg/day IV or IM. Natal measures are of utmost importance as mostly infection occurs during childbirth. Deliveries should be conducted under hygienic conditions taking all aseptic measures.000 units (for premature or low weight babies) IM twice daily for three days (if the organism is penicillin susceptible) http://en.Neonatal conjunctivitis . Systemic therapy: Neonates with gonococcal ophthalmia neonatorum should be treated for seven days with one of the following regimens Ceftriaxone 75–100 mg/kg/day IV or IM.Wikipedia.5% erythromycin ointment or 1% silver nitrate solution (Crede's method) into the eyes of babies immediately after birth Single injection of ceftriaxone 50 mg/kg IM or IV should be given to infants born to mothers with untreated gonococcal infection. Gonococcal ophthalmia neonatorum needs prompt treatment to prevent complications. Antenatal measures include thorough care of mother and treatment of genital infections when Página 3 de 4 . penicillin drops 5000 to 10000 units per ml should be instilled every minute for half an hour. natal.000 units (for full-term normal weight babies) or 20. The newborn baby's closed lids should be thoroughly cleansed and dried. Topical therapy should include Saline lavage hourly till the discharge is eliminated Bacitracin eye ointment four times per day (Because of resistant strains topical penicillin therapy is not reliable. However in cases with proved penicillin susceptibility. and post-natal care. Postnatal measures include: Use of 1% tetracycline ointment or 0. 12 hourly Ciprofloxacin 10–20 mg/kg/day or Norfloxacin 10 mg/kg/day Crystalline benzyl penicillin G 50. The advice of both the pediatrician and ophthalmologist should be sought for proper management.

Text is available under the Creative Commons Attribution-ShareAlike License. Retrieved 2007-07-12.wikipedia. additional terms may apply.medscape." (http://emedicine. Retrieved 2008-08-28.Neonatal conjunctivitis .com/article/1192190-overview).Wikipedia. 2. Wikipedia® is a registered trademark of the Wikimedia Foundation. However systemic erythromycin should also be given since the presence of chlamydia agents in conjunctiva implies colonization of upper respiratory tract as well. you agree to the Terms of Use and Privacy Policy. Retrieved 2013-08-11.eMedicine" ( a non-profit organization. "Red Book ..wikipedia. "Neonatal Conjunctivitis Treatment & Management: Treatment of Neonatal Herpetic Conjunctivitis. "Conjunctivitis.medscape.Report of the Committee on Infectious the free encyclopedia 26/04/15 04:02 Other bacterial ophthalmia neonatorum should be treated by broad spectrum antibiotics drops and ointment for two weeks. at 05:33.htm). http://en." (http://aapredbook.5% eye ointment QID for three weeks. Neonatal: Overview .aappublications.php?title=Neonatal_conjunctivitis&oldid=648433693" Categories: Diseases of the eye and adnexa Neonatology Disorders of conjunctiva Herpes simplex virus-associated diseases This page was last modified on 23 February 2015. 29th Edition. 4. Neonatal inclusion conjunctivitis caused by Chlamydia trachomatis responds well to topical tetracycline 1% or erythromycin 0. "MedlinePlus The American Academy of Pediatrics. Both parents should also be treated with systemic erythromycin. Herpes simplex conjunctivitis should be treated with intravenous acyclovir for a minimum of 14 days to prevent systemic infection.Neonatal Conjunctivitis" (http://www.[4] References 1. By using this Página 4 de 4 . Inc. See also List of systemic diseases with ocular manifestations Retrieved from "http://en.