Drug Name Classification

Action

Indication

Contraindication
Clients with hemosiderosis, hemochromatosi s, peptic ulcer, regional enteritis and ulcerative colitis. Hemolytic anemia, pyridoxineresponsive anemia, and cirrhosis of the liver.

Side Effects

Nursing Consideration
1. Take iron preparations with meals to reduce gastric irritation. 2. Identify the foods that inhibit the absorption of iron 3. Discuss the possibility of indigestion, change in the stool color (black and tarry or dark green), and constipation 4. Advise to increase intake of fruit, fiber, and fluids to minimize drug’s constipating effect 5. Explain the possible side effects that may occur.

Generic Name: Ferrous sulfate

Antianemic drugs

Brand Name: Feosol

Least expensive, most effective iron salt for PO therapy. Ferrous sulfate products contain 20% elemental iron; whereas ferrous sulfate dried products contain 30% elemental iron. The exsiccated form is more stable in air.

Prophylaxis and treatment of iron- deficiency anemia. Investigational: Clients receiving epoetin therapy (Failure to give iron supplements either IV or PO can impair the hematologic response to epoitin)

GI: Constipation, gastric irritation, nausea, abdominal cramps, anorexia, vomiting and diarrhea. These effects may be minimizes by administering preparations as a coated tablet. Soluble iron preparations may stain the teeth.

Drug Name Classification

Action

Indication

Contraindication

Side Effects

Nursing Consideration

Generic

Loop Diuretics

Furosemide

Edema

Never use with

Electrolyte and fluid effects:

1. Monitor serum

DrugName Classification

Action

Indication

Contraindication

Side Effects

Nursing Consideration

Generic name Nifedipine

Antihypertensive Drugs / Cardiovascular Drugs

Brand name Adalat

Variable effects on AV node effective and functional refractory periods. CO is slightly increased while peripheral vascular resistance is significantly decreased. Slight to no increase in HR and slight to no decrease in myocardial contractility.

Calcium channel Hypersensitivity, blocker Lactation Vasospastic (Prinzmetal's or variant) angina (except Adalat CC). Chronic stable angina without vasospasm (except Adalat CC), including angina due to increased effort (especially in clients who cannot take beta blockers or nitrates or who remain symptomatic following clinical doses of these drugs). Essential hypertension (sustainedrelease only).

CV: Peripheral and pulmonary edema, MI, hypotension, palpitations, syncope, CHF (especially if used with a beta blocker), GI: Nausea, diarrhea, constipation, flatulence, abdominal cramps, CNS: Dizziness, lightheadedness, giddiness, nervousness, sleep disturbances, headache, weakness, depression, Dermatologic: Rash, dermatitis, urticaria, pruritus, photosensitivity, erythema Respiratory: Dyspnea, cough, wheezing, SOB, respiratory infection; throat, nasal, or chest congestion. Hematologic: Thrombocytopenia, leukopenia, purpura, anemia. .

1. Document indications for therapy, other agents trialed/outcome and any sensitivity to CCBs. 2. Note any pulmonary edema, ECG abnormalities, or palpitations. Document K+ levels, BP, and cardiopulmonary assessment findings. 3. May take with or without food. Sustainedrelease tablets should not be chewed, crushed, or divided. Grapefruit juice may cause increased serum drug levels. 4. Maintain a fluid intake of 2–3 L/day to avoid constipation. There is no cause for concern if a tablet coating appears in the stool. . 5. Report any symptoms of persistent headache, flushing, nausea, palpitations, weight gain, dizziness.

Drug Name Classification

Action

Indication

Contraindication

Side Effects

Nursing Considerations

Generic Name: Magnesium Sulfate Brand name Epsom Salts

Laxativesaline /Anticonvulsant

Subclassification: Electrolyte, modifiermagnesium supplement

Magnesium (Mg) is an essential element for muscle contraction, certain enzyme system, and nerve transmission. Extracellular fluid level: 1.5 mEq/L. Mg depresses the CNS and controls convulsion by blocking release of acetylcholine at the myoneural junction. Also, Mg decreases the sensitivity of the motor and plate to acetylcholine and decreases the excitability of the motor membrane.

Used as an anticonvulsant. Lowers intracranial pressure for hypomagnesemia in patients receiving total parenteral nutrition (TPN) prevention and control of seizures in toxemia( Preeclampsia of eclampsia) acute nephritis in children and other conditions like epilepsy, glomerulone phiritis or hypothyroidism. Electrolyte additive. Also used for the treatment of lifethreatening arrhythmias

Hypermagnese mia, hypocalcemia, anuria, heart block active labor use cautiously in: Any degree of Renal insufficiency.

CNS: Drowsiness RESP: Decreases respiratory rate CV: Bradycardia, arrhythmias, hypotension GI: Diarrhea DERM: Flushing, sweating METAB: Hypothermia NEURO: Decrease deep –tendon reflexes paralysis.

ASSESSMENT: 1. Document indications for therapy, onset and characteristics of S&S. 2. Evaluate cardiac status and ECG 3.Note any kidney disease. Assess Mg levels and renal function 4. With premature labor, continually assess fetal heart rate and intensity and timing of contraindication. Antedote: Use artificial ventilation immediately. Have 510 mEq of calcium readily available for IV injection to depression. Hemodialysis and peritoneal dialysis are effective

DRUG STUDY

Submitted to: Ms. Teresita C. Natividad Clinical Instructor Submitted by: Adora S. Echevarria

Drug Name

Classification

Action

Indication

Contraindication

Side Effects

Nursing Consideration

Generic Name: Cefuroxime Sodium Brand Name: Kefurox, Zinacef

Anti-Infectives/ Cephalosporins

Interfere with a final step in the formation of the bacterial cell wall (inhibition of mucopeptide biosynthesis), resulting in unstable cell membranes that undergo lysis (same mechanism of actions of penicillin’s). Also, cell division and growth are inhibited. Most effective against young, rapidly dividing organisms and are considered bactericidal

Infections of the Hypersensitivity urinary tract to lower cephalosporins. respiratory tract (including pneumonia), skin and skin structures, bones, and joints. Septicemia, meningitis, uncomplicated and disseminated gonococal infections due to penicillinaseor nonpenicillinase – producing strains of N. gonorrhea in men and women.

GI: N&V, diarrhea, abdominal cramps or pain, dyspepsia, glossitis, heartburn Allergic: Urticaria, rashes, pruritus, fever, chills, erythema CNS: Headache, malaise, fatigue, vertigo, dizziness, lethargy, confusion

1. Cefuroxime sodium should not be added to solutions of aminoglycosides; if both drugs are require, each should be given separately to the client 2. Prior to reconstitution, protect the drug from light. The powder and reconstituted drug may darken without affecting potency 3. Take tablets with food to enhance the absorption of the PO medication 4. Report any signs of anemia (SOB, dizziness, pale skin, etc.)

Drug Name Generic Name: Ranitidine Hydrochloride Brand Name: Zantac

Classification Histamine H2 receptor antagonist

Action Competitively inhibits action of histamine on the H2 at receptor sites of parietal cells, decreasing gastric acid secretion

Indication Active Duodenal and gastric ulcer ,pathologic hypersecretory condition such as ZollingerEllison syndrome (ZES), gastroesophageal reflux disease, erosive esophagitis, heartburn

Contraindication

Side Effects CNS: vertigo, malaise, headache EENT: blurred vision Hepatic: jaundice; Other: burning and itching at injection site, anaphylaxis

Nursing Considerations 1. Assess patient for abdominal pain. Note presence of blood in emesis, stool or gastric aspirate 2. Drug may be added to total parenteral solution 3.Don’t confuse ranitidine with rimantadine 4. Instruct patient on proper use of OTC preparation, as indicated 5. Remind patient to take once daily prescription drugs at bedtime for best results. 6. Urge patient to avoid cigarette smoking because this gastric acid secretion and worsen disease 7. Advise patient to report abdominal pain and blood in stool or emesis may

increase

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