Extremity Reconstruction - 5EU Analysis and Market

Forecasts Is Released
France, Germany, Italy, Spain, and the UK. The analysis also identifies unmet needs in the market,
specifies the major drivers and barriers to device adoption, provides insight into marketed and pipeline
products, and provides an understanding of physician perception and outlook with an overall emphasis
on current and future industry trends in the 5EU.
*This is an on-demand report and will be delivered within 4 working days (excluding weekends) of the
purchase. Highlights Key Questions Answered - What is the current and future extremity reconstruction
market outlook in the 5EU region? What trends are affecting these markets? - Which are the key, high
growth markets that extremity implant manufacturers should expand into? Which markets are growing
the fastest, and what are the top-selling products in each segment? - What are the unmet needs with
extremity reconstruction products currently on the market? How will emerging technologies fulfill these
unmet needs? - What clinical factors and technical specifications influence a physician to use one
implant device over another? What is physician perception and market outlook of extremity
reconstruction? - What are the challenges and complications of extremity reconstruction that have
hindered widespread adoption?
With developing the next-generation of extremity implant products, what aspects of the technology are
device manufacturers focused on optimizing? How will new entrants impact the 5EU extremity
reconstruction market? Scope - Annualized total extremity reconstruction market revenue by type of
device, direct and indirect costs of disease, procedure trends, and market outlooks by country through
2021. - Key topics covered include strategic competitor assessment, market characterization,
identification of unmet needs, reimbursement and regulatory considerations, evaluating market access
in the 5EU region, and implications of the emerging technologies on the market. - Pipeline analysis:
Comprehensive data split across different stages of development, including a discussion of emerging
trends and extremity implant products in development. - Analysis of the current and future market
competition in the 5EU extremity reconstruction market. Insightful review of the key industry drivers,
opportunities, barriers and challenges. Each trend is independently researched to provide qualitative
analysis of its implications. Reasons to buy - What Physicians Thinkquotes provide a unique insight into
how healthcare professionals are reacting to events within the industry, and what their responses could
mean for industry strategists. In this report you will understand the perceptions of leading orthopedic
surgeons from around the world. This information is essential for all strategic decision makers in every
organization allowing them to act on high quality information.
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Table of Contents
1 Table of Contents

1.1 List of Tables
1.2 List of Figures
2 Executive Summary
2.1 Key Metrics in Major Markets
2.2 Technological Trends
2.3 Key Players in the Extremity Replacement Market
2.4 Extremities Market Future Outlook
2.5 What Do Physicians Think?
3 Introduction
3.1 Catalyst
3.2 Related Reports
4 Industry Overview
4.1 Overview
4.2 Procedure Trends
4.2.1 By Country
4.3 Market Access
4.3.1 Purchasing Decisions
4.3.2 Adoption
4.4 Brand Loyalty
4.5 Regulation
4.5.1 5EU
4.6 Reimbursement
4.6.1 5EU
4.7 Product Recalls
4.8 Mergers and Acquisitions
4.8.1 Wright Medical Merges with Tornier in $3.3 Billion All-Stock Deal (October 2015)
4.8.2 Integra LifeSciences to Acquire Total Ankle Replacement Portfolio from Tornier N.V. (September
4.8.3 Zimmer Acquires Biomet in $13.35 Billion Deal (June 2015)
4.8.4 Teijin Acquires Nakashima Medical for JPY 1.5 Billion (April 2015)
4.8.5 Stryker Acquires Small Bone Innovations for $375m (August-September 2014)
4.8.6 Wright Medical Acquires OrthoPro for $36m (February 2014)
4.8.7 Wright Medical Acquires Solana Surgical for $90m (January 2014)
4.8.8 Wright Medical Acquires Biotech International for $80m (November 2013)
4.8.9 Johnson & Johnson Acquires Synthes for $19.7 Billion (June 2012)
4.8.10 Integra LifeSciences Acquires Ascension Orthopedics for $65m (September 2011)
4.9 Economic Impact
4.9.1 Arthritis
4.9.2 High Revision Rates
5 Unmet Needs
5.1 Shoulder Replacement
5.1.1 Durable Glenoid Components
5.1.2 Augmented Glenoid Components
5.1.3 Grammont-Style Versus Frankle-Style
5.1.4 Addressing Complications of Reverse Shoulder Replacement
5.1.5 Bone-Sparing Stemless Designs: Pros and Cons
5.1.6 Revision Systems

5.1.7 Long-Term Follow-Up
5.1.8 Patient Awareness in Emerging Markets
5.1.9 Accurate Glenoid Component Positioning
5.1.10 Implant Sizing for APAC Patients
5.2 Elbow Replacement
5.2.1 Implant Survival and Fixation Techniques
5.2.2 Implant Positioning
5.2.3 Long-Term Follow-Up
5.3 Wrist Replacement
5.3.1 Long-Term Clinical Data
5.3.2 Limited Product Offerings
5.3.3 Failure and Revision Rates
5.3.4 Physiological Wrist Movement
5.3.5 Carpal Component Fixation
5.4 Digits Replacement
5.4.1 Pyrocarbon Implant Durability and Fixation
5.4.2 Improved Patient Functionality
5.5 Ankle Replacement
5.5.1 Long-Term Follow-Up
5.5.2 Commitment to Medical Education
5.5.3 Advanced Biological Fixation
5.5.4 Minimal Bone Resection
5.5.5 Mobile-Bearing Versus Fixed-Bearing
5.5.6 Bespoke Instrumentation
5.5.7 Custom Prostheses
5.5.8 Revision Components
6 Market Drivers, Barriers, and Opportunities
6.1 Driver: Rising Joint Disease Prevalence
6.1.1 Sport-Related Injuries
6.1.2 Trauma
6.1.3 Aging
6.1.4 Obesity
6.2 Driver: Increased Patient Awareness
6.3 Driver: Corporate Promotions and Continuing Medical Education
6.4 Driver: Expected Launch of CE-Marked Devices
6.5 Driver: Expanded Indications of Reverse Shoulder Replacement
6.6 Driver: Stemless Shoulder Implants in the EU
6.7 Driver: Superiority of Ankle Replacment over Ankle Fusion
6.8 Driver: Expanded Insurance Coverage for TAR
6.9 Barrier: Medical Device Excise Tax
6.10 Barrier: Postoperative Complications
6.11 Barrier: Long Learning Curve
6.12 Barrier: Alternatives to Total Joint Replacement
6.13 Barrier: Shoulder Replacement Reimbursement
6.14 Barrier: Preoperative Patient Selection for TAR
6.15 Opportunity: Pyrocarbon
6.16 Opportunity: Demand for a Comprehensive Reconstruction Portfolio

6.17 Opportunity: Computer-Assisted Navigation and Patient-Specific Instrumentation
6.18 Opportunity: Emerging Markets
6.19 Opportunity: Capitalizing on Wrist Market Fragmentation
6.20 Opportunity: TAR Expanded Indications
6.21 Opportunity: Fixed-Bearing TAR Implants in the EU
7 Competitive Assessment
7.1 Shoulder Replacement
7.1.1 Overview
7.1.2 Product Profiles - Anatomic Total Shoulder Replacement
7.1.3 Product Profiles - Anatomic Stemless Total Shoulder Replacement
7.1.4 Product Profiles - Reverse Total Shoulder Replacement
7.2 Elbow Replacement
7.2.1 Overview
7.2.2 Product Profiles
7.3 Wrist Replacement
7.3.1 Overview
7.3.2 Product Profiles
7.4 Digits Replacement
7.4.1 Overview
7.4.2 Product Profiles
7.5 Ankle Replacement
7.5.1 Overview
7.5.2 Product Profiles - Two-Component Fixed-Bearing
7.5.3 Product Profiles - Three-Component Mobile-Bearing
8 Pipeline Assessment
8.1 Overview
8.2 Product Profiles
8.2.1 AFT Proximal Humerus Fracture Prosthesis (Shoulder Options)
8.2.2 Akilos Total Ankle System (Implants International)
8.2.3 aSpire Total Shoulder Arthroplasty System (Shoulder Options)
8.2.4 Comprehensive Nano Stemless Shoulder (Zimmer Biomet)
8.2.5 Helical Conservative Shoulder Prosthesis (University of Missouri)
8.2.6 INBONE Calcaneal Stem Implant (Wright Medical)
8.2.7 Luna Stemless Humeral Prosthesis (Shoulder Options)
8.2.8 PyroCarbon Modular Radial Head (Integra LifeSciences)
8.2.9 NDSU Total Ankle Replacement Device (NDSU Research Foundation)
8.2.10 Vantage Ankle System (Exactech)
9 Clinical Trials to Watch
9.1 Overview
9.2 Discovery Elbow Long-Term Survivorship Study
9.3 Prospective Post Market Clinical Follow-up Study of the Zimmer Trabecular Metal Reverse Shoulder
9.4 An Observational Cohort Study Evaluating the Safety and Performance of Aequalis Resurfacing Head
Implant in a Consecutive Series of Patients with Shoulder Arthroplasty
9.5 Sidus(TM) Stem-Free Shoulder - A Multi-center, Prospective, Non-controlled Post Market Clinical
Follow-up Study

9.6 A Prospective, Randomized, Multicenter Study Comparing the Safety and Effectiveness of Arthrexs
Eclipse Shoulder Prosthesis to the Univers II Shoulder Prosthesis in Patients with a Degenerative Joint
9.7 Prospective Post Market Clinical Follow-Up (PMCF) Study of the Zimmer Trabecular Metal Total
9.8 Motec Versus Remotion Total Wrist Arthroplasty - A Prospective Randomized Study
9.9 A Post-market Clinical Follow-up Study of the TITAN Reverse Shoulder System Used in Primary or
Revision Total Shoulder Arthroplasty
9.10 A Prospective Multi-Center Study of the Safety and Effectiveness of the Tornier Simpliciti Shoulder
System in Shoulder Arthroplasty
9.11 Retrospective and Prospective Clinical Outcomes Study of the Zimmer Nexel Total Elbow
10 Current and Future Players
10.1 Overview
10.2 Trends in Corporate Strategy
10.3 Acumed
10.3.1 Overview
10.3.2 Portfolio Assessment
10.3.3 SWOT Analysis
10.4 Arthrex
10.4.1 Overview
10.4.2 Portfolio Assessment
10.4.3 SWOT Analysis
10.5 Corin Group
10.5.1 Overview
10.5.2 Portfolio Assessment
10.5.3 SWOT Analysis
10.6 DePuy Synthes (Johnson & Johnson)
10.6.1 Overview
10.6.2 Portfolio Assessment
10.6.3 SWOT Analysis
10.7 DJO Global
10.7.1 Overview
10.7.2 Portfolio Assessment
10.7.3 SWOT Analysis
10.8 Exactech
10.8.1 Overview
10.8.2 Portfolio Assessment
10.8.3 SWOT Analysis
10.9 Integra LifeSciences
10.9.1 Overview
10.9.2 Portfolio Assessment
10.9.3 SWOT Analysis
10.10 Kyocera Medical Corporation
10.10.1 Overview
10.10.2 Portfolio Assessment
10.10.3 SWOT Analysis
10.11 Lima Corporate

10.11.1 Overview
10.11.2 Portfolio Assessment
10.11.3 SWOT Analysis
10.12 Smith & Nephew
10.12.1 Overview
10.12.2 Portfolio Assessment
10.12.3 SWOT Analysis
10.13 Stryker
10.13.1 Overview
10.13.2 Portfolio Assessment
10.13.3 SWOT Analysis
10.14 Tornier
10.14.1 Overview
10.14.2 Portfolio Assessment
10.14.3 SWOT Analysis
10.15 Wright Medical Group
10.15.1 Overview
10.15.2 Portfolio Assessment
10.15.3 SWOT Analysis
10.16 Zimmer Biomet Holdings
10.16.1 Overview
10.16.2 Portfolio Assessment
10.16.3 SWOT Analysis
10.17 Other Players
11 Market Outlook
11.1 Company Market Share
11.1.1 By Region
11.2 By Market Segment
11.2.1 By Region
11.3 By Geography
11.3.1 France
11.3.2 Germany
11.3.3 Italy
11.3.4 Spain
11.3.5 UK
12 Appendix
12.1 Bibliography
12.2 Abbreviations
12.3 Methodology
12.3.1 Overview
12.3.2 Coverage
12.3.3 Secondary Research
12.4 Forecasting Methodology
12.5 Physicians and Specialists Included in This Study
12.5.1 Key Opinion Leaders
12.6 Primary Research Summary
12.7 About the Authors

12.7.1 Analysts
12.7.2 Global Head of Medical Devices
12.8 About GlobalData
12.9 Contact Us
12.10 Disclaimer
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