Catalogue Médecine

Datec
Distributer de Bases de données

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Sommaire
Micromedex
Reprorisk Drugdex Martindale PDR Poisindex Tomes Plus Tomes IV Index Index Nominum Diseasedex Emergency Medicine

Ovid Technologies
Reactions Weekly Circulation Pascal PsycINFO Embase Eric Francis Medline Linksolver Pack Inist

MedecineComplete
Martindale AHFS Drug Informations British National Formulary BNF for Children Clarke's Analysis of Drugs and Poisons Dietary Supplements Drug Administation via Enteral Feeding Tubes Handbook on Injectable Drugs Herbal Medicines Pharmaceutical Excipients Rules and Guidance for Pharmaceutical Manufactures and Distributors Stability-Indicating HPLC Methods for Drug Analysis Stocley's Drug Interactions Stocley's Interaction Alerts The Merck Index

Micromedex

Reprorisk:
Databases to help you evaluate human reproductive risks of drugs, chemical, and physical/environmental agents People are never more careful about their health than when they are starting a family. Exposures to even common substances can prove dangerous. The REPRORISK® System is the single, most comprehensive source of reproductive risk information available. Whether evaluating the risks of drugs or chemicals, identifying potential hazards, or counseling patients, REPRORISK content can help reduce exposures and prevent possible medical and legal complications. With information on general toxicity, fertility, genetic influences, teratogenic agents, and more, the System addresses concerns of females, males, and unborn children. The REPRORISK System comprises four databases - REPROTOX®, REPROTEXT®, TERIS, and Shepard's Catalog - ensuring complete reproductive risk data is instantly accessible in one, easy-to-use tool. Features • Covers all aspects of reproduction including fertility, male exposures, and lactation • Helps set risk-reducing priorities by combining hazard ratings and exposure estimates • Assists patients in making more informed decisions and preventive measures • Provides evidence-based, referenced data on risks of acute exposures, as well as reproductive, carcinogenic, and genetic influences Intended Users • • • • Physicians, nurses, and pharmacists Industrial hygienists and medical officers Risk and safety mangers Toxicologists

Drugdex:
Your source for comprehensive, unbiased, referenced drug information of unsurpassed breadth and depth The number of drugs available today is enormous. The vast amount of information about these drugs can be mind boggling. Using a standardized outline format, the DRUGDEX® System harnesses this information and gives you easy access to current, accurate drug knowledge you can use with confidence. Reviewed by international experts, DRUGDEX evidence-based documents cover FDA-approved and investigational prescription and nonprescription drugs, as well as non-U.S. preparations. Areas discussed include dosage, pharmacokinetics, cautions, interactions, clinical applications, adverse effects, comparative efficacy, drug of choice information, and orphan drug status. Features • Provides evidence-based, unbiased, fully referenced information • Contains independently reviewed data from major drug centers and pharmacology services worldwide • Decreases risk of adverse drug events and saves valuable time by delivering data at the point of care • Helps determine off-label uses • Designated an official compendium for drug utilization review and screening Intended Users • Healthcare professionals who prescribe, order, dispense, administer, or research drugs • Drug safety and information professionals • Research and development • Medical affairs professionals • Medical and pharmacy school faculty and students

Martindale:
Your easy-to-use, electronic, international drug reference from the Pharmaceutical Press, London, UK. These days people and products travel across international boundaries in a matter of hours, often bringing with them unfamiliar medications or other remedies. This electronic version of MARTINDALE: The Complete Drug Reference provides extensive, unbiased information on drugs and related substances in clinical use worldwide. Complete with therapeutic data, synonyms, and manufacturer brand names, MARTINDALE offers sections with summaries of relevant information, referenced abstracts, and reviews providing expanded information. Features • • • • Provides quick, easy access to in-depth international drug information Contains over 600 disease treatment reviews to assist with treatment protocols Includes summaries for more than 150,000 proprietary products from 37 countries Presents brand names, manufacturer, country of origin, active constituents, and licensed uses

Intended Users • Pharmacists in tourist and high travel areas such as coastal cities, business centers, capitals • Drug information centers, pharmacy and medical schools, and libraries • All healthcare professionals caring for international patients and concerns

PDR:
Instant access to the trusted drug information source you've counted on for years. Familiar and firmly established, the PDR® is a staple with healthcare professionals everywhere. Whether in a pharmacy, clinic, physician office, or library, the PDR is a recognized resource for information on thousands of current FDA-approved drugs. This electronic version of the PDR gives you instant access to all the information contained in the PDR, the PDR® for Nonprescription Drugs and Dietary Supplements, and the PDR® for Ophthalmic Medicines.. The Library makes it easy to search and retrieve data on drug interactions, side effects, dosages, uses, contraindications, and more. Features • • • • Contains detailed FDA-approved package insert information Delivers crucial data quickly and in a familiar, easy-to-reference format Includes photos, charts, tables, and chemical structures for convenient comparison Offers additional references: • Stedman's® Medical Dictionary • PDR® for Herbal Medicines Pharmacists in healthcare and industry All healthcare-related professionals Drug information and safety specialists Research and development Medical affairs personnel

Intended Users • • • • •

Poinsindex:
Trusted, evidence-based resource to help you quickly identify, manage, and treat toxicological exposures Accidental poisonings occur with even the most common and seemingly harmless substances. In such situations, having instant access to critical information can save lives. Relied upon in 100% of U.S. poison control centers, the POISINDEX® System identifies ingredients for hundreds of thousands of commercial, biological, and pharmaceutical products. The System links that information directly to management documents providing data on clinical effects, range of toxicity, and treatment protocols for exposure. POISINDEX also delivers concise, essential toxicology data on a single screen to ensure the fastest access to critical answers. Features • Presents immediate answers for toxic exposure management • Contains evidence-based, authoritative data reviewed and evaluated by clinical experts • Delivers current, accurate information updated quarterly • Offers superior search capabilities for fast, easy retrieval of information Intended Users • Poison and drug information specialists • Emergency department personnel • Clinical toxicologists

Tomes Plus:
Medical and hazard risk reference to help you safely manage chemicals in the workplace and the environment Handling hazardous chemicals is routine in many workplaces. Precautions must be in place to protect workers and to meet regulatory and safety guideline compliance. The TOMES Plus® System offers rapid, easy access to the critical medical and hazard data needed for immediate, effective response to any situation. Whether reducing the risk of injury or determining safe levels of exposure, TOMES Plus databases include treatment guidelines for acute chemical exposures, evacuation procedures, personal protection procedures, and chemical containment and disposal information. General areas unrelated to chemicals are addressed such as ergonomics and human health risk assessment. The System's proprietary and government databases are integrated to ensure quick access to the fully reviewed, referenced information. Features • Provides critical information to maintain and manage safe, healthy workplaces • Assists in assessing and implementing on-site solutions to chemical spills, exposures, explosions, etc. • Delivers accurate, up-to-date data in a single, reliable resource • Helps evaluate exposures, facilitate rapid emergency response, and meet regulatory compliance Intended Users • • • • • Industrial hygienists and hazardous waste chemists Safety & risk managers Emergency responders Environmental engineers and toxicologists Occupational health physicians and chief medical officers

Tomes:
Medical and hazard data to help you safely manage chemicals in the workplace and the environment Handling hazardous chemicals is routine in many workplaces. Precautions must be in place to protect workers on a daily basis and when accidents occur. The TOMES® System offers rapid, easy access to the critical medical and hazard data needed for immediate, effective response to such situations. Designed to help reduce the risk of exposure and injury, TOMES databases include treatment guidelines for acute chemical exposures, evacuation procedures, personal protection data, and chemical disposal information. General areas unrelated to chemicals are addressed such as ergonomics and human health risk assessment. The System's three databases - MEDITEXT®, HAZARDTEXT®, and INFOTEXT® - are integrated to ensure quick access to the fully reviewed, referenced information. Features • Provides critical information to maintain and manage safe, healthy workplaces • Assists in assessing and implementing on-site solutions to chemical spills, exposures, explosions, etc. • Delivers accurate, up-to-date data in a single, reliable resource • Helps evaluate exposures, facilitate rapid emergency response, and meet regulatory compliance Intended Users • Safety & risk managers • Toxicologists • Occupational health physicians and chief medical officers

IV Index:
Your instant answer to IV compatibility questions with easy-to-interpret information When multiple IV medications are combined, the risk of complication is very real. Efficacy of one or more drugs can be reduced or a potentially dangerous incompatibility can occur. The IV INDEX® System provides easy access to proven data to help ensure accurate IV compatibility decisions can be made at the point of care with confidence. The new IV INDEX features the parenteral compatibility piece of Trissel's™ 2, the latest database from the ultimate authority on IV compatibility - Lawrence Trissel. IV INDEX includes over 50,000 compatibility results and 600 unique drugs and solutions. IV INDEX also supports confident decisions with multiple studies and full study information including manufacturer, concentration, stability, and other conditions. Features • • • • • • 600 unique drugs and solutions Over 50,000 compatibility results Solution, Y-Site, syringe, and admixture compatibility information TPN/TNA data Allows for either single or multiple drug searches Uses a word wheel for easy drug name lookup

Intended Users • Nurses and physicians needing quick, reliable answers at the point of care • Pharmacists responsible for IV infusions

Index Nominum:
Your international guide to drugs and derivatives from 133 countries These days people travel across continents as easily as they travel across town. With them come countless medications that are unfamiliar in some countries or carry a different name than those prescribed locally. The Thomson Reuters version of Index Nominum is an international drug directory providing synonyms, formulas, and therapeutic classes for drugs and derivatives for 133 countries. Edited by the Swiss Pharmaceutical Society, this database contains area-specific information for preparations used in medicine. Features • Helps identify international drugs by trade and generic names, synonyms, therapeutic category, chemical structure, CAS number, manufacturer, or country • Contains convenient contact information for approximately 10,000 manufacturers and distributors around the world • Carries worldwide recognition as a trusted, premier pharmaceutical reference Intended Users • • • • • Medical professionals in healthcare and industry Poison and drug information centers Drug safety and information specialists Research and development professionals Medical and pharmacy schools and students

Deseasedex Emergency medicine:
The premier emergency medicine resource to aid you with patient diagnosis and treatment in acute care settings. Emergency care professionals are held accountable for knowing more than is humanly possible. Imagine having instant access to extensive data on everything from common emergencies (e.g., stroke) to unusual disorders (e.g., Reye's Syndrome). The DISEASEDEX™ Emergency Medicine System supports diagnosis and treatment decisions, prevents medical errors, and improves outcomes. Written by practicing clinicians, DISEASEDEX Emergency Medicine is evidence-based and instantly answers the "what, when, and how" of emergency medicine. Features • Helps improve patient care by providing evidence-based medical knowledge presented at the summary level with quick access to information specific to the practice of urgent and acute care medicine. • A single source, designed to save precious time in an emergency situation. • Pre-hospital care protocols offer guidelines for diagnosis and treatment of patients in the pre-hospital environment. • Includes Emergency Medical Abstracts (EMAs) that cover a broad scope of topics and intentionally challenge traditional practices and long-standing emergency medical myths. Intended Users • Emergency department clinical staff including physicians, physician assistants, nurses, nurse practitioners • Rapid, accurate diagnosis and treatment in emergency situations • Obtaining reliable, critical data when minutes count

OVID TECHNOLOGIES

Reactions Weekly

Reactions Weekly is the unique one-stop-shop for all your adverse drug reaction needs, bringing you up-to-the minute summaries of the world's adverse drug reaction news and comprehensive coverage of published adverse drug reaction case reports. Reactions Weekly provides a weekly round-up of adverse drug reaction news including labelling changes, drug withdrawals due to safety issues, adverse reaction research and current issues in drug safety. Content is sourced from journals, scientific meetings, media releases, regulatory agency and pharmaceutical company websites, and bulletins from the more than 80 National Centers that participate in the WHO International Drug Monitoring Programme. Reactions Weekly has comprehensive coverage of adverse drug reaction case reports published in the literature, through monitoring of all Medline- and Embase-indexed journals. All case summaries contain data as specified by the CIOMS II guidelines for International Reporting of Periodic Drug-Safety Update Summaries, providing you with the most pertinent information in an easy-to-read format. Overdose, interaction, serious and first published case reports are highlighted; US FDA MedWatch criteria for classifying serious reactions are used and all first reports are verified by a search of the world's literature. Contextual adverse event data from the WHO Adverse Drug Reactions database are included for first reports.

Circulation
A range of original articles relevant to cardiovascular disease Circulation publishes original contributions of scientific excellence concerned with clinical and laboratory research relevant to cardiovascular disease. The research articles are from many disciplines including cardiovascular medicine and surgery, epidemiology, radiology, and pathology, to appeal to cardiologists, internists, cardiovascular surgeons, nurses, and others interested in cardiovascular medicine. Coverage includes Cardiovascular News, Clinical Cardiology, From Bench to Bedside, Images in Cardiovascular Medicine, and the AHA Calendar. Recommended for cardiologists, cardiovascular surgeons, electrophysiologists, internists, nurses and others interested in cardiovascular medicin

PASCAL
PASCAL is a multilingual multidisciplinary bibliographic database in Science,Technology and Medicine. PASCAL covers the core scientific literature in Science, Technology and Medicine with special emphasis on European literature. Because of its multidisciplinary coverage, PASCAL is especially useful when searching for documents on a topic at the interface between several disciplines and seldom covered in specialized databases. With over 17 million records from 1973 to the present; 90% of the records since 2000 contain author abstracts. Keywords are in French, English and Spanish. The subject coverage is: * Medical, Pharmaceutical and Psychological Sciences 31% * Life Sciences, Biology 22% * Engineering Sciences 20% * Physics and Mathematics 15% * Earth and Space 7% from the following source documents: * Journal articles - 88% (3,085 international titles) * Proceedings - 9% * Dissertations, books, patents, reports - 3% * Chemical Sciences 5% Broad Subjects: Clinical Medicine; Life Sciences; Health Professions Specific Subjects: Multidisciplinary Life & Medical Sciences

PsycINFO
The essential psychology tool for researchers, practitioners, and students in numerous disciplines,PsycINFO� is an abstract database that provides systematic coverage of the psychological literature from the 1800s to the present. The American Psychological Association's PsycINFO� database is the comprehensive international bibliographic database of psychology. It contains citations and summaries of peer-reviewed journal articles, book chapters, books, dissertations, and technical reports, all in the field of psychology and the psychological aspects of related disciplines, such as medicine, psychiatry, nursing, sociology, education, pharmacology, physiology, linguistics, anthropology, business, and law. Journal coverage, spanning 1806 to present, includes international material selected from more than 2,450 periodicals from more than 49 countries written in 29 languages. Current chapter and book coverage includes worldwide English-language material published from 1987 to present. Over 80,000 records are added annually through weekly updates. More than 36 million references in over 870,000 journal articles, books, and book chapters; retrospective to 2001 and earlier, where available; more than 3.2 million references from 1920 to 2000. Broad Subjects: Clinical Medicine; Behavioral & Social Sciences Specific Subjects: Psychology; Behavioral Science

Embase
Embase is a biomedical and pharmacological database containing bibliographic records with citations, abstracts and indexing derived from biomedical articles in peer reviewed journals, and is especially strong in its coverage of drug and pharmaceutical research. EMBASE contains over 12 million records from 1974 to present, with 600,000+ citations and abstracts added annually. Each record contains the full bibliographic citation, indexing terms and codes; 80% of all citations in EMBASE include author-written abstracts. The EMBASE journal collection is international with roughly 7,000 active peer-reviewed journals from 70 countries. Broad biomedical scope covering the following areas: * Drug therapy and research, including pharmaceutics, pharmacology and toxicology * Clinical and experimental (human) medicine * Basic biological science relevant to human medicine * Biotechnology and biomedical engineering, including medical devices * Health policy and management, including pharmacoeconomics * Public, occupational and environmental health, including pollution control * Psychiatry and mental health, including substance dependence and abuse * Forensic science * Alternative and complementary medicine Broad Subjects: Clinical Medicine; Pharmacology; Life Sciences; Forensic Medicine Specific Subjects: Biology, General; Psychiatry; Epidemiology & Public Health; Substance Abuse; Alternative Medicine; Bioengineering & Biotechnology; Pharmaceuticals; Pharmacology

ERIC
ERIC provides unlimited access to more than 1.2 million bibliographic records of journal articles and other education-related materials, with hundreds of new records added twice weekly. If available, links to full text are included. ERIC indexes education journals, the majority of which are peer-reviewed. Most of these journals are indexed comprehensively - that is, a record for every article in each issue is included in ERIC. Some journals are indexed selectively - that is, only those articles that are education-related are selected for indexing. In addition to the journal literature, ERIC indexes education-related materials from scholarly organizations, professional associations, research centers, policy organizations, university presses, the U.S. Department of Education and other federal agencies, and state and local agencies. Individual contributors submit conference papers, research papers, dissertations, and theses. Within the ERIC Collection, you will find records for: * journal articles * books * research syntheses * conference papers * technical reports * policy papers * other education-related materials Broad Subjects: Behavioral & Social Sciences Specific Subjects: Education

Francis
FRANCIS is a multilingual, multidisciplinary database providing indepth coverage of the humanities and social sciences, with abstracts for 80% of its records since 2000. Because of its interdisciplinary nature, FRANCIS is especially useful for finding documents on topics at the interface between several disciplines and seldom covered in specialized databases. Its broad subject areas and international scope make FRANCIS an ideal stand-alone social science database, as well as a suitable complement for more specialized databases. FRANCIS contains over 3 million bibliographic recors from 1972 to the present with 80% of the records since 2000 containing abstracts. Its subject coverage includes: * Social Sciences: Administrative Sciences, Business Management, Economics, Education, Energy Economics, Ethnology, Geography, Public Health, Information Science, Latin America, Computers and Law, Sociology. * Humanities: Archeology, Art History, History of Science, Literature, Linguistics, Philosophy, Prehistory and Protohistory, Psychology, Religion. The source documents include: * Journal articles 79% * Books 9% * Proceedings, reports, dissertations, exibition catalogs 7% * Other 5% Each file in FRANCIS has its specific vocabulary. All files are indexed in French and in English. The Latin America and History of Sciences files are also indexed in Spanish and the Computer Processing and Legal Sciences file is also indexed in German. Broad Subjects: Humanities; Behavioral & Social Sciences Specific Subjects: Multidisciplinary

MEDLINE
The premier, comprehensive biomedical database from one of the leading sources of medical and healthcare and available on OvidSP. Updated daily, MEDLINE on OvidSP offers you seamless and up-to-the-minute access to the latest bibliographic citations and author abstracts from more than 3,900 biomedical journals published in more than 70 countries. Astracts are included more than 75% of the records. The full MEDLINE product on OvidSP includes: - Access to Ovid MEDLINE In-Process & Other Non-Indexed Citations, which is Ovid's collection of non-indexed NLM records, both the in-process records as well as PubMed records not in MEDLINE. - Access to OLDMEDLINE: the National Library of Medicine's online database of approximately 1,700,000 citations to articles from international biomedical journals covering the fields of medicine, preclinical sciences and allied health sciences from 1948 through 1965. - Subject limits based on PubMed's subject subsets. The addition of these subsets allows users to easily restrict a broad search to their specific area of interest: AIDS, Bioethics, Cancer, Complementary Medicine, History of Medicine, Space Life Sciences, Systematic Reviews, Toxicology. Other features include: • Ovid Evidence-Based Medicine Reviews Limit provides quality filter to quickly identify authoritative and relevant evidence and also provides link to article and topic reviews (separate purchase necessary). • Advanced mapping that analyzes users' natural language queries and suggests appropriate terms for searching. • Graphical controlled vocabulary thesaurus that contains Medical Subject Headings (MeSH) to describe the subject of each journal. • Emulation of "dot-dot" and NLM search syntax. Collections for Medline (1950-Date) (MEDL-DB-I66): • Euro-Package: Medline/EBMR 2 users • Euro-Package: Medline/EBMR 5 users • Haiti Earthquake Disaster Relief Effort Broad Subjects: Clinical Medicine; Nursing; Life Sciences; Health Professions

LinkSolver
Introducing the next generation of linking Ovid LinkSolverTM, a comprehensive resource linking solution, expands the power of linking to a wide variety of Internet resources, while giving you complete administrative flexibility in defining, organizing and displaying links for your end-users. Ovid LinkSolverTM - The right tool for you Ovid LinkSolverTM is the preferred choice in next generation universal linking solutions. LinkSolverTM is: • Flexible: define, organize and display links that are relevant to your organization and end-users. • Scalable: you'll have an online service model that grows with your needs. • Priced right: enjoy an extraordinary value for the best linking resources and features available. • Easy to upgrade: your set-up is simple and quick. • Robust: our worldwide data centers optimize user performance and uptime reliability. • Ovid hosted: we host the servers, you save valuable budget dollars on hardware and maintenance costs. • Now Supports Non-English Characters: Ovid LinkSolver is now able to fully resolve, display and pass along inbound links from Ovid SearchSolver and other sites that send properly configured OpenURLs containing non-English characters. This also means that Journals A-Z will enable title browsing in Japanese and Korean, in addition to Dutch, English, French, German, Italian, Polish, Spanish, and Swedish. Users can also search and retrieve journal titles in those languages. Ovid LinkSolverTM: Easy to use, easy to administer. Ovid LinkSolverTM is easy to set up, administer, and use. You define the links based on your library�s resources and your patrons� workflow. The result is simple, one-click access to a range of valuable resources. Easy to use Ovid LinkSolverTM creates comprehensive linking from OpenURL compliant information sources to Internet resources. You define the scope of your electronic library, while your users enjoy navigation to a world of relevant resources. Use LinkSolverTM to: • Enjoy more accurate linking -- Ovid LinkSolverTM enables you to select journal coverage by year, or volume and issue and can handle appropriate copy resolution. • Enable one-click access from Ovid and WebSPIRS® databases to full text journal articles in Journals@Ovid, on publisher websites, from CrossRef member publishers, or from locally held collections. • Establish links to a variety of relevant Internet or Intranet resources--Amazon.com, governmental sites, educational institutions, local knowledge bases, and more. • Link to print resource information from your library's OPAC. • Link to document ordering suppliers and inter-library loan systems.

Easy to administer Because you configure Ovid LinkSolverTM through a centralized link administration interface, you can: • Save time and effort -- Ovid LinkSolverTM requires no PERL programming. • Select from preset link templates, representing thousands of journals from primary publishers and aggregators; or create your own link sources. • Customize link names and resources that your users see. • Limit searches from Ovid databases to all full text to which your institution subscribes. • Expand administration globally or restrict to a single site -- Ovid LinkSolverTM supports the demands of consortia and multi-site institutions. • Upload electronic subscription lists from an OPAC or other serials management tools through Ovid's import utility. • Enjoy quick deployment -- Ovid LinkSolverTM is set up and ready to use in no time. • Link to proxy servers for remote user access to links. • Enable end-users to link directly from cited references in Journals@Ovid content to all sources of link resources. Now, a single link from a search query is your key to a wealth of relevant information. It's yours to explore through the power of Ovid LinkSolverTM.

Pack

Pack Inist Sciences Sociales: (Eric/Francis/Madline/linksolver) Pack Inist Sciences: (Eric/Francis/Madline/linksolver/Pascal)

MedicinesComplete

Martindale:
Your easy-to-use, electronic, international drug reference from the Pharmaceutical Press, London, UK. These days people and products travel across international boundaries in a matter of hours, often bringing with them unfamiliar medications or other remedies. This electronic version of MARTINDALE: The Complete Drug Reference provides extensive, unbiased information on drugs and related substances in clinical use worldwide. Complete with therapeutic data, synonyms, and manufacturer brand names, MARTINDALE offers sections with summaries of relevant information, referenced abstracts, and reviews providing expanded information. Features • • • • Provides quick, easy access to in-depth international drug information Contains over 600 disease treatment reviews to assist with treatment protocols Includes summaries for more than 150,000 proprietary products from 37 countries Presents brand names, manufacturer, country of origin, active constituents, and licensed uses

Intended Users • Pharmacists in tourist and high travel areas such as coastal cities, business centers, capitals • Drug information centers, pharmacy and medical schools, and libraries • All healthcare professionals caring for international patients and concerns

AHFS Drug Information :
AHFS Drug Information, published by the American Society of Health-System Pharmacists (ASHP), has been the leading source of evidence-based drug information available to health care professionals for almost 50 years. The quality and consistency of the information make it the most widely respected drug reference for addressing critical questions that require objective evidence. It is evidence-based and peer-reviewed by over 500 pharmacists, physicians, and other health care professionals and is supported by extensive objective research from primary sources. AHFS DI is compiled without the influence of manufacturers, insurers, regulators or other interested parties.AHFS DI includes: • Uses included in the labelling approved by the US Food and Drug Administration and uses that are unlabeled but wellestablished in the scientific literature • Over 1,200 monographs on over 50,000 drug products • Unlabeled uses linked to evidence-based references • 75,000 references linked to more than 500,000 content elements • 50,000 references with hyperlinks to PubMed citations in the National Library of Medicine’s database for access to full-text of articles • Drug interactions, cautions, and toxicity alerts • Detailed information on dosage and methods of administration • Thorough examination of well-established laboratory and test inferences • Includes a brief chemical, structural, and/or pharmacologic description; structure-activity relationships are described when applicable; stability and storage information about reconstituted and/or diluted preparations • Expanded descriptions of all pharmacologic activities and effects are included; pharmacokinetics describing the absorption, distribution, and elimination characteristics of a drug • Regular updates incorporate official therapeutic guidelines from National Institutes of Health, Centers for Disease Control, American Heart Association, American Academy of Family Practice, and dozens of other medical societies.

British National Formulary
The BNF is published jointly by the British Medical Association and the Royal Pharmaceutical Society of Great Britain. This essential reference provides up-to-date, practical guidance on prescribing, dispensing, and administering medicines. The BNF evaluates clinical evidence from diverse sources with information validated by a network of clinical experts and is published under the authority of a Joint Formulary Committee. The BNF reflects current best practice as well as legal and professional guidelines relating to the uses of medicines. The resource includes: • Guidance on the drug management of common conditions • Details of medicines with special reference to their uses, cautions, contra-indications, side-effects, doses, and relative costs • Guidance on prescribing, monitoring, dispensing, and administering medicines Purpose • To provide rapid reference to essential information on the selection of safe and effective medicines for individual patients • To provide authoritative, impartial, and where available, evidence-based advice on prescribing, dispensing, and administering medicines • To reflect promptly changes in product availability as well as emerging safety concerns and shifts in clinical practice Updates The content is revalidated, revised, and updated on a biannual basis. Focus Medicines prescribed in the UK are covered and those considered less suitable for prescribing are clearly identified. Little or no information is included on medicines promoted for purchase by the public. Audience • Doctors and other prescribers • Pharmacists • Dentists • Nurses • Other healthcare professionals • Students training to join the health professions

Uses • Designed for rapid reference • To find information on the choice of medicines for a given condition • To find information about the clinical properties of a specific medicine • To find practical guidance on how to prescribe, dispense, administer or monitor a medicine • To advise patients about their medicines • As an educational tool for students training to join the health professions and for continuing professional development

BNF for Children :

This practical online resource provides the definitive source of analytical data for drugs and poisons. It is intended for use primarily by scientists faced with the need to identify and quantify these substances in body fluids, tissue samples and pharmaceutical and industrial products. 31 Sections cover all practice areas and analytical procedures used in analytical toxicology including drugs and alcohol in driving, drugs in sport, workplace drug testing and postmortem toxicology. Purpose • To represent the combined knowledge of the analytical and forensic toxicology community • To provide an unrivalled depth of global coverage • To be the definitive source of analytical data for drugs and poisons Uses • As a teaching resource for students and new staff • For information about appropriate analytical methods for specific groups or individual drugs • For application in drug development, in clinical cases and in forensic investigations • Information on therapeutic drugs, drugs of abuse, pesticides and other substances Key Coverage • Immunoassays, ultraviolet, visible and fluorescence spectrophotometry • Infra-red, near-infrared, Raman and nuclear magnetic resonance spectroscopy • Mass spectrometry • Thin-layer, gas and high performance liquid chromatography • Capillary electrophoresis • Additional information includes applications of analytical toxicology techniques in areas such as: – Hospital, forensic and post-mortem toxicology – Alcohol, drugs and driving – Workplace drug testing – Analysis of hair and saliva – Drug abuse in sport – Therapeutic drug monitoring – Poisoning by natural toxins – Volatile substance abuse – Pesticide poisoning

– Poisoning by metals and anions – Over 1730 monographs detailing physical properties, analytical methods, pharmacokinetic data, ultraviolet, infra-red and mass spectra, and therapeutic and toxicity data of drugs and poisons – Expanded indexes and appendices including CAS Registry Number, empirical formula, molecular weight, TLC, GC and HPLC systems data, and therapeutic class Updates The content is revalidated or revised annually. This process involves both scheduled, in-depth revision on a chapter-bychapter basis and updates in reaction to new information as it arrives. Focus Clarke’s Analysis of Drugs and Poisons contains unrivalled data gathered from simple chemical methods to complex instrumental techniques. Audience • Pharmaceutical analysts • Forensic and clinical toxicologists • Clinical pharmacologists • Clinical and forensic laboratories • Poison information centres • Pathologists, hospital pharmacists

Clarke's Analysis of Drugs and Poisons
This practical manual and standard reference work is intended for use primarily by scientists faced with identifying and quantifying drugs and poisonous substances in body fluids, tissue samples and pharmaceutical and industrial products. Ideal for use in forensic and crime labs, clinical pharmacology departments, poison information centers, pathology and toxicology departments, and pharmacies. Completely revised and expanded, this third edition has been written by over 40 international experts, and also boasts an editorial advisory board of over 45 world renowned scientists. Purpose • To represent the combined knowledge of the analytical and forensic toxicology community • To provide an unrivalled depth of global coverage • To be the definitive source of analytical data for drugs and poisons Uses • As a teaching resource for students and new staff • For information about appropriate analytical methods for specific groups or individual drugs • For application in drug development, in clinical cases and in forensic investigations • Information on therapeutic drugs, drugs of abuse, pesticides and other substances Key Coverage • Immunoassays, ultraviolet, visible and fluorescence spectrophotometry • Infra-red, near-infrared, Raman and nuclear magnetic resonance spectroscopy • Mass spectrometry • Thin-layer, gas and high performance liquid chromatography • Capillary electrophoresis • Additional information includes applications of analytical toxicology techniques in areas such as: – Hospital, forensic and post-mortem toxicology – Alcohol, drugs and driving – Workplace drug testing – Analysis of hair and saliva – Drug abuse in sport – Therapeutic drug monitoring – Poisoning by natural toxins – Volatile substance abuse

– Pesticide poisoning – Poisoning by metals and anions – Over 1730 monographs detailing physical properties, analytical methods, pharmacokinetic data, ultraviolet, infra-red and mass spectra, and therapeutic and toxicity data of drugs and poisons – Expanded indexes and appendices including CAS Registry Number, empirical formula, molecular weight, TLC, GC and HPLC systems data, and therapeutic class Updates The content is revalidated or revised annually. This process involves both scheduled, in-depth revision on a chapter-bychapter basis and updates in reaction to new information as it arrives. Focus Clarke’s Analysis of Drugs and Poisons contains unrivalled data gathered from simple chemical methods to complex instrumental techniques. Audience • Pharmaceutical analysts • Forensic and clinical toxicologists • Clinical pharmacologists • Clinical and forensic laboratories • Poison information centres • Pathologists, hospital pharmacists

Dietary Supplements
Dietary Supplements provides a comprehensive guide, for community pharmacists and health professionals, to the most commonly used vitamins, minerals, and dietary supplements. This revised and expanded edition: • • • • • Contains monographs on 72 commonly available dietary supplements Presents research findings on the therapeutic use of these products Discusses the law relating to dietary supplements in the UK, Europe and the USA Reliably informs on efficacy and safety Covers human requirements and dietary sources of various vitamins and minerals

Purpose • To provide online access to the latest Dietary Supplement information available • To provide a useful online resource for health professionals advising patients on the safe use and prescription of Dietary Supplements • To provide a lead-in to the published evidence base Uses • When you need concise, accurate information about supplements • For information on safety and efficacy of supplements • For an update on regulations relating to dietary supplements in UK, Europe and USA • For information regarding interactions with conventional medicines Key Coverage • Includes over 100 comprehensively referenced monographs, informed by the latest research and evidence. • Full revisions and updates regularly made to all monographs. • New monographs are included with each online update. • Regulations relating to dietary supplements in UK, Europe and the USA • Useful appendices including a summary of interactions with conventional medicines • Advanced text searching Updates

Every six months new monographs are written and current monographs are updated with the latest research and evidence. Audience • Community pharmacists • Dieticians • Nutritionists • Pharmacy students (undergraduate and postgraduate) • CAM practitioners • Healthcare professionals

Drug Administration via Enteral Feeding Tubes

An overview of enteral feeding tubes, drug administration techniques, considerations for dosage form selection, common drug interactions with enteral formulas, and methods to minimize tube occlusion is given. Purpose Allows users to make quick, accurate assessments of the compatibility of various solutions and additives with a particular drug; therefore, health care professionals get exactly what they need to know about injectable drugs…any time they access MedicinesComplete.com. Uses • Answers to frequently asked questions on the preparation, storing and administration of injectable drugs • Allows users to find monographs within AHFS Drug Information (also at MedicinesComplete) by listing the AHFS classification numbers for each drug • Helps pharmacists maximize patient safety and enhance medication effectiveness • Provides quick and accurate assessments of the compatibility of various solutions and additives with a given parenteral drug Key Coverage • 359 drug monographs (13 brand-new), with information accumulated from 2,723 references, including 100 new to this edition – all fully referenced • Drugs listed alphabetically by generic name for efficient searching, with brand names also searchable • Four compatibility tables are provided for each drug: solution, additive, syringe, and Y-site • Key product data including common sizes, strengths, volumes, and forms in which the drug is supplied. Also includes pH, osmotic value, and other important product information • Storage requirements and general stability information, including pH, freezing, exposure to light, sorption and filtration characteristics, and repackaging information • Tabulated results from primary research on the compatibility of the listed drug with infusion solutions and other drugs

Updates The content will be re-validated and revised after scheduled, in-depth revisions, or on a monograph-by-monograph basis, and updates will occur as new information arrives. Audience • Pharmacists (especially those interested in intravenous drug mixing and administration in various settings) • Physicians • Nurses • Healthcare Professionals requiring referential information on injectable drugs

Handbook on Injectable Drugs
Handbook on Injectable Drugs (HID), by the ASHP and Lawrence Trissel, is the ultimate authority on compatibility and stability of injectable drugs. HID brings together comprehensive information on 359 parenteral drugs commercially available in the United States and in other countries, and offers pharmacists and health care professionals a precise, reliable way to make their organisations safer for patients. For almost 30 years this comprehensive, user-friendly resource has been widely recognised and trusted as the authority on injectable drug information. No other drug reference examines parenteral drug stability and compatibility in such extensive detail. Purpose Allows users to make quick, accurate assessments of the compatibility of various solutions and additives with a particular drug; therefore, health care professionals get exactly what they need to know about injectable drugs…any time they access MedicinesComplete.com. Uses • Answers to frequently asked questions on the preparation, storing and administration of injectable drugs • Allows users to find monographs within AHFS Drug Information (also at MedicinesComplete) by listing the AHFS classification numbers for each drug • Helps pharmacists maximize patient safety and enhance medication effectiveness • Provides quick and accurate assessments of the compatibility of various solutions and additives with a given parenteral drug Key Coverage • 359 drug monographs (13 brand-new), with information accumulated from 2,723 references, including 100 new to this edition – all fully referenced • Drugs listed alphabetically by generic name for efficient searching, with brand names also searchable • Four compatibility tables are provided for each drug: solution, additive, syringe, and Y-site • Key product data including common sizes, strengths, volumes, and forms in which the drug is supplied. Also includes pH, osmotic value, and other important product information • Storage requirements and general stability information,

including pH, freezing, exposure to light, sorption and filtration characteristics, and repackaging information • Tabulated results from primary research on the compatibility of the listed drug with infusion solutions and other drugs Updates The content will be re-validated and revised after scheduled, in-depth revisions, or on a monograph-by-monograph basis, and updates will occur as new information arrives. Audience • Pharmacists (especially those interested in intravenous drug mixing and administration in various settings) • Physicians • Nurses • Healthcare Professionals requiring referential information on injectable drugs

Herbal Medecines
The use of complementary and alternative medicines (CAM) has increased rapidly over recent years and the global market for herbal products has risen dramatically. Written by experts in the fields of pharmacognosy, phytochemistry, phytopharmacy, clinical herbal medicines, phytopharmacie and regulation of herbal medicinal products, Herbal Medicines is an invaluable online resource for pharmacists and other healthcare professionals who require evidence-based information on herbal medicines used for treatment and prevention of health problems. Purpose • To address the issues of quality, safety and efficacy by providing scientifically rigorous, impartial, evidencebased, information on medicinal herbs • To enable the healthcare professional to advise on the rational and safe use of herbal medicines Uses • For information about the constituents of a herbal medicinal product • For information about the clinical indication and dosage of a herbal medicinal product • For data on the safety and interactions of a herbal medicine • To find a product or manufacturer from over 35 countries Key Coverage • Chemical structures and photographs of the plant and crude drug material • Over 150 monographs, comprehensively referenced, detailing phytochemical, pharmacological and clinical aspects of each herb • Uses, dosage, evidence of efficacy, adverse effects, contraindications, use in pregnancy and lactation, drug interactions, etc. • Detailed Monographs on around 20 major herbal medicines, including: – echinacea – evening primrose – ginkgo – ginseng – St John’s wort – valerian • Fully searchable content

Updates All the content is revalidated or revised annually. This process involves both scheduled, in-depth revision on a herb-by-herb basis and updates in reaction to new information as it arrives. Focus International coverage includes product information from the following countries: • Argentina • Australia • Austria • Belgium • Brazil • Canada • Chile • Czech Republic • Denmark • Finland • France • Germany • Greece • Hong Kong • Hungary • India • Ireland • Israel • Italy • Malaysia • Mexico • Netherlands • New Zealand • Norway • Portugal • Russia • Singapore • South Africa • Spain • Sweden • Switzerland • Thailand • Turkey • United Arab Emirates • United Kingdom • USA • Venezuela Audience • Pharmacists • CAM practitioners • Healthcare Professionals

Pharmaceutical Excipients
Pharmaceutical Excipients is a comprehensive guide to the uses, properties and safety of pharmaceutical excipients. It is an internationally acclaimed online resource recognised as one of the most authoritative and comprehensive sources of information on excipients used in pharmaceutical formulation. Written by over 120 pharmaceutical scientists from around the world, expert in the manufacture, analysis or use of excipients, it is an essential reference for those involved in the development, production, control and regulation of pharmaceutical preparations. Purpose • To provide pharmaceutical formulators with a guide to the uses, safety, chemical and physical properties of over 300 pharmaceutical excipients Uses • Information on the physical properties of individual excipients with comparative data on different grades from the same or different suppliers • Detailed information on types of formulations where an excipient has been used along with safety data in both people and animals • Locating a trade-name or supplier of an excipient from the world-wide listing of manufacturers Key Coverage • Contains 340 fully referenced excipient monographs • Recently added monographs include: – Calcium Chloride – Coconut Oils – Phospholipids – Potassium Alum – Sulfur Dioxide – Tagatose • Provides information on the uses and chemical and physical properties of excipients systematically collated from a variety of international sources, including: – pharmacopeias – patents – primary and secondary literature – websites – manufacturers’ data • Chemical structures and SEMs of many excipients • Appendices of E numbers, EINECs and PubChem ID numbers and molecular

weights • Essential data on the physical properties of excipients such as: – boiling point and compression characteristics – hygroscopicity – flowability – melting point – moisture content – moisture-absorption isotherms – particle size distribution – rheology – specific surface area – solubility • Extensively linked monographs, contents list, and appendices • Advanced text searching • Extensive data on the applications, licensing and safety of excipients • Comprehensively cross-referenced and indexed, includes many additional excipients as related substances • Fully searchable international supplier’s directory and detailed information on trade names and specific grades or types of excipients commercially available Updates The content is revalidated or revised annually. This process involves both scheduled, in-depth revision on an excipient-by-excipient basis and updates in reaction to new information as it arrives. Focus Detailed information about new excipients as well as those used for many years. Information on materials used in confectionery, cosmetics and foods as well as pharmaceutical applications. Audience • For those involved with the development, production, control and regulation of pharmaceutical preparations • Also of value to those with an interest in the formulation or production of confectionery, cosmetics and food products

Rules and Guidance for Pharmaceutical Manufactures and Distributors
Product Description Since its first publication in 1971, Rules and Guidance for Pharmaceutical Manufacturers and Distributors (commonly known as “The Orange Guide”) has been an essential reference for all involved in the manufacture or distribution of medicines in Europe. The Orange Guide collates in one convenient and authoritative source European and UK guidance documents and information on legislation relating to the manufacture and distribution of medicines for human use. Compiled by the Inspection and Standards Division, Medicines and Healthcare products Regulatory Agency (MHRA), London, UK. Purpose To bring together the main pharmaceutical regulations, directives and guidance which manufacturers and wholesalers are expected to follow when making and distributing medicinal products in the European Union and European Economic Area. Key Coverage • Detailed changes to the EU guide to good manufacturing practice • Detailed revisions to the EU Directive on medicinal products for human use • The new Directive on the Principles and Guidelines on Good Manufacturing Practice of Medicinal Products for Human Use Updates Content is revised on a regular basis to take into account changes to European and national legislation and guidance documents. All revised content undergoes a series of rigorous checking procedures. Focus Covers the UK and EU Member countries Audience • Holders of pharmaceutical manufacturer’s licences • Holders of pharmaceutical wholesale dealer’s licences • Qualified Persons (QPs) • Responsible Persons (RPs) • Global relevance

Stability-Indicating HPLC Methods for Drug Analysis
Product Description Stability-Indicating HPLC Methods for Drug Analysis is the only compilation of stability-indicating high-performance liquid chromatographic (HPLC) analytical methods – 1,028 in all – that have appeared in the published literature. By turning first to this reference, analysts will avoid the tedium of lengthy literature searches. Purpose To provide readily available and convenient access to the published literature on stability-indicating HPLC assays. An essential for the busy analyst who has no time to perform lengthy literature searches by helping them to identify suitable, previously validated, stability-indicating HPLC methods. Uses Provides users with a unique reference that focuses only on stability-indicating HPLC methods, a specialised subset of all HPLC methodologies – useful to those involved with evaluating drug stability, dosage form development, quality control, and drug regulation. Authors Quanyun A. Xu, PhD, is Research Scientist, Pharmacology Research Laboratory, Division of Pharmacy and Pharmaceutical Development Center, Division of Cancer Medicine, University of Texas M.D. Anderson Cancer Center, Houston, Texas. Lawrence A. Trissel, FASHP, is Research Consultant, TriPharma Research, Ponte Vedra Beach, Florida, and author of other works including Trissel’s™ Stability of Compounded Formulations and Handbook on Injectable Drugs. Key Coverage • Monographs prepared from 851 published references and present 1,028 stability-indicating HPLC methods that have been described in published literature • A compilation of 1,028 stability-indicating HPLC analytical methods – 178 new to this edition – that have been described in the published literature • Information on 572 different drug entities – 96 new – presented in structured monographs containing 30 elements • A more in-depth, extensive description of the HPLC analysis presented in the literature than the sketchy outline formats that have appeared elsewhere

• Unique in focusing on stability-indicating HPLC methods, a specialised subset of all HPLC methodologies. Updates The content will be revalidated and revised after scheduled, in-depth revisions, or on a monograph-by-monograph basis, and updates will occur as new information arrives. Audience Analysts involved in evaluating drug stability, dosage form development, quality control, and drug regulation.

Stocley's Drug Interactions
Product Description Stockley’s Drug Interactions provides the healthcare professional with quick and easy access to clinically relevant, evaluated, and evidence-based online information on interactions between therapeutic drugs, proprietary medicines, herbal medicines, foods, drinks, pesticides and drugs of abuse. Based upon the many thousands of published clinical papers and reports, Stockley’s Drug Interactions provides a series of detailed yet concise monographs designed for quick and easy reference. Purpose • To provide the busy healthcare professional with quick and easy access to clinically relevant, evaluated and evidence-based information on drug interactions. Uses For answers to the following practical questions… • Are the drugs in question known to interact or is the interaction only theoretical and speculative? • If they do interact, how serious is it? • Are all patients affected or only a few? • Is it best to avoid these two drugs altogether or can the interaction be accommodated in some way? • What alternative and safer drugs can be used instead? Key Coverage • Over 17,000 drug interactions in 3,100 monographs • Fully referenced • Designed for quick and easy access • Tailored thesaurus allows selection of appropriate search terms • Intuitive interactions and full text search options • Ability to enter up to 12 drugs at a time • Search by approved names, international trade names, and other synonyms including drug codes Updates All the content is revalidated and revised regularly. New and updated information is added quarterly. Audience • Pharmacists • Clinicians • Healthcare Professionals

Stocley's Interaction Alerts
Product Description Stockley’s Drug Interactions is the world’s most comprehensive and authoritative international reference source on drug interactions, covering therapeutic drugs, proprietary medicines, herbal medicines, foods, drinks, pesticides and some drugs of abuse. Stockley’s Interaction Alerts are derived from the full text publication to provide healthcare professionals with a quick way to check for potential interactions in a clinical setting. In essence the Alerts summarise drug-drug, drugherb and drug-food interactions in a few short lines to give a quick ready-reference to whether drugs can safely be taken together. As well as being available on MedicinesComplete, the Alerts are deliverable in XML and are designed to be easily integrated into prescribing and dispensing systems. Overview Each Alert comprises of a two-part interaction message: • The first part gives a description of the interaction • The second part gives guidance on the management of the interaction The Alerts are rated using three separate categories (see below): The Alert includes an indication of the relevant route of administration for each interacting combination. For those with access to Stockley’s Drug Interactions, links to the corresponding monographs provide access to detailed and fully referenced discussions of each interaction. Updates Stockley’s Interaction Alerts are updated and revalidated on a monthly basis. The entire database now contains over 40,000 alerts. Audience • Pharmacists • Clinicians • Healthcare Professionals

The Merck Index
The Merck Index is a world renowned reference source for chemical, pharmaceutical and biomedical information that contains more than 10,000 monographs, 28 supplemental tables and 450 organic name reactions. For over 100 years, The Merck Index has provided critically evaluated, peerreviewed, and authoritative information on compounds of significance in research, commerce and environmental impact. The electronic version is updated semi-annually and includes entries archived from previous print editions. Broad subject coverage The monograph section provides descriptions of more than 18,000 substances across multiple scientific disciplines including: • Drugs for humans and animals • Organic chemicals used in research and manufacturing • Plants and traditional medicines • Natural products, toxins and biologicals • Agricultural chemicals, pesticides, and herbicides • Food additives and nutritional supplements • Fragrances, flavours, cosmetics, dyes, stains and colours Your index to chemical information Each monograph provides a concise description of a compound’s activity and importance with data such as: • Chemical structure depiction • Molecular formula, weight and percentage composition • Physical properties and toxicity data • Scientific and patent literature references • Therapeutic and commercial uses • Caution and hazard information • An extensive collection of synonyms includes; chemical, common and generic names; trademarks and associated companies; manufacturer codes; CAS Registry Numbers Special collections The Organic Name Reactions include reactions schema and key references. The Therapeutic Category Index provides over 370 classifications hyperlinked to over 4000 monographs. Supplemental Tables include a collection of hard-to-find biomedical and chemical information, for example the Chemical Terms Translator, Company Register, Vaccines, Acronyms used in Chemistry and Biomedical Sciences, Monosaccharide Structures, Physical Constants and Radioactive Isotopes Used in Medicine.

Value added digital access • Monographs and organic name reactions have hyperlinks to related entries • Therapeutic category index has hyperlinks to monograph entries • Includes almost 1000 monographs archived from previous editions • Search over 18,000 substances, view organic name reactions, and gather background information from Supplemental Tables Quick reference to fundamental information on compounds of current importance • More than 700 new and completely rewritten monographs plus significant updates to more than 40% of the existing monographs • Trademarks and manufacturers updated for more than 600 compounds • Expanded focus on “Green Chemistry” and compounds of environmental significance • Continued coverage of drugs and pharmaceuticals • Biotech drugs - monoclonal antibodies, recombinant products, anti-sense therapies, therapeutic vaccines • Traditional and alternative medicines • Orphan drugs • New mechanisms of action • New cosmetic ingredients, fragrances, and flavours • All information is critically evaluated, peer-reviewed, and authoritative Target audience: Chemists, biochemists, pharmacists, toxicologists, educators, students, academic libraries, academic researchers, information professionals, attorneys, journalists, and emergency first responders What makes The Merck Index unique: • No other source provides the amount of concise, accurate and topical information across multiple scientific disciplines in an easy-to-use quick reference format • Editorial staff have already identified, evaluated and verified key data to save time for busy researchers • Citations to important journal articles and reviews quickly point to additional information on each compound • Time-honoured reputation for authoritative information; chemistry’s constant companion for 119 years.