Decreased O2 flow to the

kidney
Renal Dysplasia

Juvenile Polycystic Disease

Adult Polycystic Disease

Proximal tubule & Medulla

most affected
MC Cystic Disease flank
mass in newborns
Newborn w/ a unilateral
mass
Potters facies
Oligohydramnios
AR- Cant survive
AD Bilateral disease
HTN can lead to berry
aneurysms (bloody brain)
o Worst headache
ever
Assoc. w/ MVP

Diabetic glomerulopathy
Hyaline arteriosclerosis
Proteinuria 3.5g/24hr
Caused by hypertension

Minimal Change Disease

MCC of Nephrotic syndrome
in children
Due to T-cell production of
cytokines.
Loss of negative charge on
the GBM
Hypoalbuminemia
causing Ca
Fused podocyte feet
Tx: improve w/
corticosteroids

Progressive Cresentic
glomerulonephritis
Can occur after taking
penicillin
Hematuria, RBC casts
Progressive renal failure
Generalized palpable
purpura
p-ANCAs
Goodpastures syndrome

Hemoptysis followed by
acute renal failure
Hematuria, proteinuria and
RBC casts
Linear IF
IgG anti-basement
membrane

Diffuse proliferative
glomerulonephritis

Focal Segmental
glomerulosclerosis

Type II MPGN

Rapidly progressive Cresentic

glomerulonephritis

MC type of glomerulonephritis
in patients with SLE
Photophobia and stiffness in
joints
Subendothelial IC deposits
anti-DS DNA Abs
+ granular IF

Black male w/ AIDS

MC cause of Nephrotic
syndrome in adults
Proteinuria
Thickness of GBM
Low serum C3
Progress to CRF
Intramembranous deposits
Rapid loss of renal function
Associated w/
Goodpastures & Wegeners
(p-ANCA)
Linear IF

Alport Syndrome

Acute Post-Streptococcal GN

Type I MPGN

Type IV SLE glomerulonephritis

IgA glomerulopathy

Medullary Sponge Kidney

Juvenile autosomal recessive

polycystic kidney disease

Staghorn Calculus

X linked recessive
Mutation of Type IV
Collagen
Sensorineural hearing loss
and ocular abnormalities
Negative IF and EM
Type III Rxn
Smokey colored urine
Subepithelial depositsIF
granular
follows strep A inf.
Anti-DNAase B Abs
RBC cast
Associated w/ HBV & HCV
Subendothelial IF granular
deposits
Tram-Track
Anti-dsDNA Abs
Wire looping
Granular IF
Episodic hematuria
Associated w/ HenochSchonlein purpura. (Type III)
Hematuria and RBC cast
Overall MC type
Striations in papillary ducts
discovered w/ IVP
Recurrent UTIs and renal
stones
Potters face- low set ear
broad base nose etc
Oligohydramnios
AR- PK`HD1 gene mutation
Cysts also in liver
Chronic urinary Tract
infections
LARGE stones causing
hydronephrosis
Triple phosphate crystal
Caused by a Proteus
species

x
Acute Drug-induced TIN

Alkaline urine

Eosinophilia/Eosinophils in
urine
Type I & IV Hypersens Rxn
Sterile pyruia (NO bacteria
and WBC cast)
Occurs after taking
penicillin type drug or
NSAIDS
Post Tx from acute sinusitis
Very common in Native
Americans
Sterile pyruia
Kidney is MC extra
pulmonary site
Unilateral abdominal mass
in child w/ hypertension
HTN due to renin secretion
from tumor
MC primary renal tumor in
KIDS
Abortive glomeruli
mesonophreic mesoderm
MCC is Smoking
Microscopic hematuria
6-7th decade of life
Associated w/ Mental
Retardation & Tuberous
Sclerosis
Bilateral Solid Mass
Aniline dye exposure
Affects Renal pelvis
Smoking MCC

Renal TB

Wilms Tumor

Renal Cell Carcinoma

Angiomyolipoma

Transitional Cell Carcinoma

Nephritic Syndrome
Nephrotic Syndrome
Acute pyelonephritis

Malignant HTN

Medullary segment of TAL

Calcium Phosphate Stones

Orthostatic proteinuria

Phanacetin abuse also

cause
Analgesic abuse
RBC cast KEY findings
Proteinuria is >150mg/day
Fatty casts are KEY finding
Hypercholesterolemia
Fever
WBC casts
Vesicoureteral reflux
Flea-bitten kidney (pinpoint
hemorrhages on cortical
surface)
Hyaline arteriolosclerosis
Necrotizing glomerulitis
Most susceptible to
Ischemia
MC stone in children
associated w/ increased
diary
Functional proteinuria that
occurs w/ standing
mailmen
Diffuse Membranous
Glomerulopath
Thick GBM
Fatty Cast w/ Maltese
Crosses
2nd MCC of nephrotic
syndrome in adults
SubEPIthelial deposits of
ICs
SPIKE AND DOME
appearance
Granular IF
Assoc. w/ HBV and
Captopril (ACEi)
Type III Hypersen Rxn.

Chronic RENAL FAILURE

Renal papillary Necrosis

Acellular WAXY cast

BUN and Cr (renal azo)
PTH (Ca) ( Vit D)
Phosphorus
Chronic drug-induced
tubulointerstitial nehritis
ring deformities in the
kidney= absence or renal
papillae
FIXED specific gravity