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REDEFINE

YOUR FUTURE
Incorporating innovative science into the
development of personal care and nutritional
products gives you exclusive access to a
premier anti-aging business opportunity. By
leveraging the growing anti-aging megatrend with
scientifically proven ageLOC products, Nu Skin
empowers you to build and share your business
with others. Experience an opportunity thats
unsurpassed in the anti-aging industry
discover the difference demonstrated today.

WE ARE THE
FUTURE OF
ANTI-AGING

Glance forward in timesee a more youthful you. Your


complexion appears smoother and more radiant. Your
body feels healthier and more vibrant. At Nu Skin were
committed to helping you achieve the best version of you.
With state-of-the-art skin care solutions and nutritional

supplements formulated to help you defy the aging process,


you have the tools you need. And now, with our exclusive
science, you can look and feel young. ageLOC products
are the only internal/external product systems developed
from Nu Skins proprietary anti-aging science that targets

the sources of aging. Skin care for the outside and


supplements for the inside bring your mind and body
back into balance. Working together these products
create a perfect formulagiving you the key to living
younger longer.

YOUTHFUL AGING

The human body is a miracle. It naturally learns, evolves,


and repairs itself. In fact, it is designed to live young.

We are all born with internal aging defense mechanisms designed to resist the effects of aging.
But over time, external and internal influences can disrupt natural youthful activity of these
mechanisms and accelerate aging effects in the body.

Exclusive Science

At Nu Skin, we are continually researching how gene expression affects our aging defense
mechanisms. This enables us to create products that better target the sources of aging. ageLOC
Y-Span promotes the expression of key groups of genes to support healthy aging defense
mechanisms, which provide the body with powerful, protective anti-aging support.

WHAT ARE AGING


DEFENSE MECHANISMS?

Aging defense mechanisms are


the bodys way of promoting the
healthy regulation of damage
and repair processes. However,
as we age, changes in gene
expression cause the bodys
aging defense mechanisms to
decline in function, performance,
and ability.

Unique Ingredient Blend

LIVE MORE YOUTHFUL YEARS


No one wants to look or feel old. Even as we age, we all want
our bodies and minds to continue feeling youthful and healthy.
The key is to give the body what it needs so it can continue to
do what it is designed to dolive young.
Introducing Nu Skins most advanced anti-aging supplement
ageLOC Y-Span. This revolutionary supplement is designed
to promote your youth spanthe years you can enjoy life
being more active, energetic, and healthy.

maintains
The power is in ageLOC Y-Spans innovative ingredient blend that provides nutrients not readily ageLOCY-Span
available even from a healthy diet. We carefully selected ingredients not only for their nutritional and supports the activity and
function of the bodys aging
contribution, but also for their:
defense
mechanisms
by
1. Unique health benefits
positively modulating gene
2. A
 bility to positively affect gene expression.
expression, helping us to live
youthfully.
The result? An innovative formula that strengthens and supports aging defense
mechanismshelping you age youthfully.

Remarkable Results

ageLOC Y-Span promotes the bodys natural ability to fight aging by


boosting our internal aging defense mechanisms.
As our most advanced anti-aging supplement ever, ageLOC Y-Span:
1. Targets our innate ability to resist aging at its source.
2. Positively modulates gene expression with a unique blend of nutrients
3. Influences multiple aging defense mechanisms to provide broad-spectrum nutritional benefits.

ageLOC Y-SpanLive more youthful years.

HOW DO WE LIVE MORE YOUTHFUL YEARS?


What does it mean to defy your age? For those in their late
teens to their 20s, it could mean preserving their youth. For
those in their 30s to 40s, it might mean slowing down the
aging process. Those in their 50s to 60s, this may perhaps
entail good health for a longer period of time. And for those
in their 70s and above, this may possibly involve more strength
and a sound mind.
Defying your age is striving for a quality life. With ageLOC
technology, we are no longer cornered into how generations
are previously classified. Todays senior citizens think and
act differently from their counterparts times pastafter
retirement, they look forward to second lease in their life, may
it be another career or endeavor. And the young professionals
are on the lookout for other opportunities aside from their
careers, while considering their health more and more.

The Human Body is a Miracleit naturally learns, evolves, and


repairs itself. We are all born with aging defense mechanisms
designed to resist the effects of aging.
Unfortunately, lifestyle and environment can disrupt these
defenses and accelerate aging.
AGELOC Y-SPAN
Supports your bodys innate aging defense mechanisms and
provides systemic anti-aging benefits. It is our most advanced
anti-aging supplement for adults of any age.
ageLOC Y-Span can help prolong the years you can be
active, energetic and healthythe years you can enjoy life. Its
about having Youth Span.

ageLOC Y-Span Ingredients

MAJOR BODY
SYSTEMS PROTECTED

ADM

Brain and Immune Health

Vitamin D3

ADM

Astaxanthin

Heart and Metabolic Health


Bone and Joint Health

ADM

Fish Oil

Citrus
Bioflavonoid

Lycopene

Eyes and Physical Performance


ADM

ADM

LTO ORDER PROCESS

Skin Health
Purple Corn
Extract

CoQ10

ADM

Alpha Lipoic
Acid

Resveratrol

Aging Defense Mechanisms (ADM)

Rosemary
Leaf Extract

D-limonene

D-Limonene

Quercetin

Antioxidant
Protection
Cellular
Stress
Response

Improve
Metabolism

ADM
Tissue
Regeneration

DNA
Protection

A unique blend of
nutrients that can
positively influence
gene expression
& is not readily
available even from
a healthy diet.

Inflammatory
Balance

STEP:

Go to lto.nuskin.com and select Philippines as your home market.


NU SKIN PRODUCT INFORMATION PAGE

ORDERING PROCESS

STEP:

STEP:

Click ORDER NOW

Enter the information needed then click CONTINUE

AGELOC Y-SPAN
LIMITED TIME OFFER
THE POWER TO DEFY YOUR AGE
ageLOC Y-Span, a revolutionary supplement that helps
revitalize your aging defense mechanisms. Nu Skins most
advanced anti-aging supplement ever, ageLOC Y-Span is
designed to promote your youthful years, so you can enjoy
life being more active, energetic, and healthy.

ORDER NOW

STEP:

Verify the information and proceed to click CONTINUE.

STEP:

Select the quantity you want to purchase and click CONTINUE

AGELOC Y-SPAN

Live more youthful years with ageLOC Y-Span. This product


promotes the optimal expression of key groups of genes and
delivers enhanced nutritional benefits. It supports healthy aging
defense mechanisms and provides the body with powerful,
protective anti-aging support to help one age youthfully.*
PH0000000

PhP 56,000

a.)Verify the quantity; b.) select your payment method and fill the information;
c.) click the checkbox of the agreement statement to confirm; d.) Submit your order
once all the information are correct.

STEP:

1000

Remember to keep the web reference number in case you want to


check the status of your order.

a.
ageLOC Y-Span

PhP 56,000

The power is in ageLOC Y-Spans innovative ingredient


blend that provides nutrients not readily available even
from a healthy diet. We carefully selected ingredients for
their unique health benefits and ability to positively impact
gene expression. The result: an innovative formula that
strengthens and supports our aging defense mechanisms.
ageLOC Y-Span gives you the power to defy your age.*

ageLOC Y-SpanLive more youthful years.

AGING INSIGHTS
The aging population is increasing and younger
people want to avoid early signs of aging.1
Seniors are not accepting traditional elderly
stereotypes. They want to retainor regaintheir
youth. They may have aged in years, but their
attitudes are as young as ever. 2
Todays grandparents dont feel like they look or act
like the grandparents of a generation ago. 2
Many seniors are delaying retirement to help them
stay active and maintain their current lifestyles. 3
2535 year olds take a very hands-on approach to
their health care, often turning to the Internet for more
information on their health and supplement options. 4
Many parents are having children later in life and worry
about maintaining their health and energy levels.5

CONCEPT
The human body is a miracle. It naturally learns, evolves,
and repairs itself. In fact, it is designed to live young.

This LTO Pack is composed of 10 bottles of ageLOC Y-Span.


*These statements have not been evaluated by the Food and Drug Administration.
This product is not intended to diagnose, treat, cure, or prevent any disease.

STEP:

POSITIONING STATEMENT
Introducing ageLOC Y-Span, a revolutionary supplement
that helps revitalize your aging defense mechanisms.
Nu Skins most advanced anti-aging supplement ever,
ageLOC Y-Span is designed to promote your youth span
the years you can enjoy life being more active, energetic,
and healthy.*

1000

PhP 56,000

1000

PhP 56,000
PhP 56,000

b.

ageLOC Y-Span

PhP 56,000

1000
1000

PhP 56,000
PhP 56,000
PhP 56,000

We are all born with internal aging defense mechanisms


designed to resist the effects of aging. But over time,
external and internal influences can disrupt natural
youthful activity of these aging defense mechanisms and
accelerate aging effects in the body.
No one wants to look or feel old. Even as we age, we all
want our bodies and minds to continue feeling youthful
and healthy. The key is to give the body what it needs so it
can continue to do what it is designed to dolive young.
At Nu Skin, we have a unique understanding of how gene
expression affects our aging defense mechanisms. This
enables us to create products that target the sources of
aging. ageLOC Y-Span promotes the optimal expression
of key groups of genes and delivers enhanced nutritional
benefits. It supports healthy aging defense mechanisms
and provides the body with powerful, protective antiaging support to help us age youthfully.*

Aging Population and Advanced Product Offerings Drive the Global


Anti-Aging Products Market, Prweb, 2014
2
Dont Call Me Grandma, Mintel, May 2011
3
Age of Adventure, Mintel, October 2010
4
 Spotlight On Gen YFindings from Healthy World Report, Televox,
2013
5
The Ideal Age to Have a Baby, Psychology Today, June 2012
1 

c.
d.

*These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.
www.nuskin.com.ph

WHAT MAKES THIS PRODUCT UNIQUE?


Our most advanced anti-aging supplement ever,
ageLOC Y-Span targets our innate ability to resist
aging at its source.*
Contains a unique blend of nutrients that is not readily
available from even a healthy diet.*
Built on more than three decades of scientific
knowledge.*
Created with our scientific understanding of the
expression of key groups of genes related to the aging
process, as well as antioxidant and nutritional science.*
Positively modulates gene expression to support
healthy aging defense mechanisms.*
Influences multiple aging defense mechanisms to
provide broad-spectrum nutritional benefits.*
It is SCS certified. Measure the antioxidant difference
ageLOC Y-Span is making in your body.*

10

PRIMARY BENEFITS
1. Our most advanced anti-aging supplement ever,
ageLOC Y-Span targets our innate ability to resist aging
at its source.*
2. ageLOC Y-Span positively modulates gene expression
with a unique blend of nutrients that are not readily
available from even a healthy diet.*
3. ageLOC Y-Span influences multiple aging defense
mechanisms to provide broad-spectrum nutritional
benefits and to promote healthy:*
Systemic balance
Cellular response
DNA integrity
Systemic cytokine responses
Antioxidant protection
Brain
Eyes
Heart
Skin
Immune function
Bones
Joints
Lipid metabolism
Physical performance

COMPLEMENTARY PRODUCTS
ageLOC R2helps you renew and recharge with two
powerful formulas. ageLOC R 2 Night optimizes each
cells natural purification process, and ageLOC R 2 Day
optimizes cellular energy production.*

Pharmanex Solutionsprovide targeted benefits to


complement the anti-aging benefits of ageLOC
Y-Span.* Please read all information and warning labels
when combining supplements and consult your physician
if you have any questions or concerns about your
supplementation regimen.
g3this gc superfruit juice is validated by science to
support cellular rejuvenation and immune health.
Deliciously sweet, yet slightly tart, g3 provides powerful
antioxidant protection while supporting healthy immune
function.*
FREQUENTLY ASKED QUESTIONS
What are aging defense mechanisms?
Aging defense mechanisms are the bodys way of fighting
off and maintaining resistance to aging aggressors by
promoting the healthy regulation of damage and repair
processes. As we age, changes in gene expression cause
the bodys aging defense mechanisms to decline in
function, performance, and ability. ageLOC Y-Span
maintains and supports the activity by positively
modulating gene expression, helping us to live youthfully.*

What is contained in the ageLOC Y-Span ingredient


blend that is hard to find in a regular diet?
Our ingredient screening led to the identification of several
natural ingredients not common in foods consumed on a
regular basis, even among individuals who strive to eat a
healthy diet. Ingredients that met our unique criteria are
purple corn extract,4,7 alpha lipoic acid,1,4,6,7 D-limonene,*7
CoQ10,1 citrus bioflavonoids and resveratrol. Other
ageLOC Y-Span ingredients, although found in healthy
diets, have been included in amounts consumers have a
difficult time obtaining from their diet alone. These include
astaxanthin,1,2,3 rosemary extract,7 EPA, DHA, vitamin D,7
and quercetin.

WHO SHOULD USE THIS PRODUCT?


Men and women 18 and over who want to maintain their
youth and live a healthier, more youthful life.

*Some markets use Orange Oil as a source of D-Limonene


1-7
This ingredient not found in: 1 South & Central America; 2 Thailand;
3
Pacific Region; 4 EMEA; 5 Japan; 6 Korea; 7 Greater China

*These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.
www.nuskin.com.ph

What is different about the ageLOC Y-Span capsules?


ageLOC Y-Span takes advantage of a unique technology,
called Licap, that allows delivery of both liquids and solids
together in a hard shell capsule. Delivering ageLOC
Y-Span through this technology improves the
bioavailability of fat-soluble ingredients, which helps
ensure the delivery of anti-aging benefits.*
How is ageLOC Y-Span different from LifePak?
ageLOC Y-Span and LifePak were designed in different
ways, with different science. We designed LifePak with
the best nutritional and antioxidant science. We
formulated ageLOC Y-Span using all three anti-aging
sciences: our proprietary gene expression science
combined with key antioxidant and nutritional elements
for the most advanced anti-aging product possible.*
Can I take ageLOC Y-Span with ageLOC R 2?
Yes, you can take ageLOC Y-Span and ageLOC R 2
together. Gene expression science guided the
development of both products, however, we assessed
their ingredient blends for distinct benefits. We
formulated ageLOC R 2 with benefits targeting cellular
energy and cellular purification; whereas we formulated
ageLOC Y-Span to support aging defense mechanisms,
which guard against cellular response disruption,
strengthen the bodys ability to protect and repair DNA,
and provide more broad-spectrum health benefits.*
Can I take ageLOC Y-Span with other Pharmanex
products?
Yes, ageLOC Y-Spans gene expression science and
ability to remind our bodies how to be young complement
our many other supplements. ageLOC Y-Span targets
the sources of aging by influencing gene expression that
impacts your aging defense mechanisms. It does this with
a unique ingredient blend not easily found even in a
healthy diet. These unique ingredients and their ability to
positively modulate gene expression make ageLOC
Y-Span an excellent core product and a powerful
companion to your daily supplement regimen. Please
consult your physician if you have any questions about
your supplementation regimen.*
ageLOC Y-Span also contains the impressive aging
defense properties provided by omega-3 fatty acids from
fish oil. If you take a fat-binding product, such as DuoLean
or FibreNet, it is important to take ageLOC Y-Span two
hours before or after taking the fat-binding product.*

Will ageLOC Y-Span increase my skin carotenoid score?


Yes, in our ingredient selection process to identify natural
substances that target aging defense mechanisms, we also
identified a few ingredients that will positively impact your
antioxidant status.*
Has Nu Skin conducted studies on ageLOC Y-Span?
There are several ageLOC Y-Span studies completed or
ongoing.
DIRECTIONS FOR USE
Take two capsules twice daily with morning and evening
meals.
KEY SCIENTIFIC STUDIES
Studies to Support Ingredients Present in All Global
Formulas
1. Garg, A., S. Garg, L. J. Zaneveld and A. K. Singla
(2001). Chemistry and pharmacology of the Citrus
bioflavonoid hesperidin. Phytother Res 15(8): 655669.
2. Schmidt, S., F. Stahl, K. O. Mutz, T. Scheper, A. Hahn
and J. P. Schuchardt (2012). Different gene
expression profiles in normo- and dyslipidemic men
after fish oil supplementation: results from a
randomized controlled trial. Lipids Health Dis 11: 105.
3. Bouwens, M., O. van de Rest, N. Dellschaft, M. G.
Bromhaar, L. C. de Groot, J. M. Geleijnse, M. Muller
and L. A. Afman (2009). Fish-oil supplementation
induces antiinflammatory gene expression profiles in
human blood mononuclear cells. Am J Clin Nutr
90(2): 415-424.
4. Morrow, D. M., P. E. Fitzsimmons, M. Chopra and H.
McGlynn (2001). Dietary supplementation with the
anti-tumour promoter quercetin: its effects on matrix
metalloproteinase gene regulation. Mutat Res 480481: 269-276.
5. Devaraj, S., S. Mathur, A. Basu, H. H. Aung, V. T.
Vasu, S. Meyers and I. Jialal (2008). A dose-response
study on the effects of purified lycopene
supplementation on biomarkers of oxidative stress. J
Am Coll Nutr 27(2): 267-273.
Studies to Support Ingredients Present in All Global
Formulas Except Greater China
1. Yoon, W. J., N. H. Lee and C. G. Hyun (2010).
Limonene suppresses lipopolysaccharide-induced
production of nitric oxide, prostaglandin E2, and proinflammatory cytokines in RAW 264.7 macrophages.
J Oleo Sci 59(8): 415-421.
2. Lean, M. Punab, A. J. Silman, D. Vanderschueren, F.
C. Wu and E. s. group (2009). Association between

*These statements have not been evaluated by the Food and Drug Administration.
www.nuskin.com.ph
This product is not intended to diagnose, treat, cure, or prevent any disease.
www.nuskin.com.ph

11

25-hydroxyvitamin D levels and cognitive


performance in middle-aged and older European
men. J Neurol Neurosurg Psychiatry 80(7): 722-729.
3. Zhu, H., D. Guo, K. Li, J. Pedersen-White, I. S.
Stallmann-Jorgensen, Y. Huang, S. Parikh, K. Liu and
Y. Dong (2012). Increased telomerase activity and
vitamin D supplementation in overweight African
Americans. Int J Obes (Lond) 36(6): 805-809.
4. Pengelly, A., J. Snow, S. Y. Mills, A. Scholey, K.
Wesnes and L. R. Butler (2012). Short-term study on
the effects of rosemary on cognitive function in an
elderly population. J Med Food 15(1): 10-17.

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Studies to Support Ingredients Present in Many of the


Global Formulas
1. Villalba, I. Tunez, F. Perez-Jimenez and J. LopezMiranda (2013). Postprandial antioxidant gene
expression is modified by Mediterranean diet
supplemented with coenzyme Q(10) in elderly men
and women. Age (Dordr) 35(1): 159-170.
2. Schrauwen, E. C. Mariman and E. E. Blaak (2013).
The effects of 30 days resveratrol supplementation
on adipose tissue morphology and gene expression
patterns in obese men. Int J Obes (Lond).
3.Li, J., M. K. Kang, J. K. Kim, J. L. Kim, S. W. Kang, S.
S. Lim and Y. H. Kang (2012). Purple corn
anthocyanins retard diabetes-associated
glomerulosclerosis in mesangial cells and db/db mice.
Eur J Nutr 51(8): 961-973.
4.Tsuda, T., F. Horio, K. Uchida, H. Aoki and T. Osawa
(2003). Dietary cyanidin 3-O-beta-D-glucoside-rich
purple corn color prevents obesity and ameliorates
hyperglycemia in mice. J Nutr 133(7): 2125-2130.
5.Djordjevic, B., I. Baralic, J. Kotur-Stevuljevic, A.
Stefanovic, J. Ivanisevic, N. Radivojevic, M.
Andjelkovic and N. Dikic (2012). Effect of astaxanthin
supplementation on muscle damage and oxidative
stress markers in elite young soccer players. J Sports
Med Phys Fitness 52(4): 382-392.
6. K. Lee and Y. M. Kim (2003). Astaxanthin inhibits
nitric oxide production and inflammatory gene
expression by suppressing I(kappa)B kinasedependent NF-kappaB activation. Mol Cells 16(1):
97-105.
7. Stoll, S., H. Hartmann, S. A. Cohen and W. E. Muller
(1993). The potent free radical scavenger alpha-lipoic
acid improves memory in aged mice: putative

relationship to NMDA receptor deficits. Pharmacol


Biochem Behav 46(4): 799-805.
8. Liu, J. (2008). The effects and mechanisms of
mitochondrial nutrient alpha-lipoic acid on improving
age-associated mitochondrial and cognitive
dysfunction: an overview. Neurochem Res 33(1):
194-203.
9. Errero-Barbudo, C., B. Soldevilla, B. Perez-Sacristan,
I. Blanco-Navarro, M. Herrera, F. Granado-Lorencio
and G. Dominguez (2013). Modulation of DNAInduced Damage and Repair Capacity in Humans
after Dietary Intervention with Lutein-Enriched
Fermented Milk. PLoS One 8(9): e74135.

REDEFINE
YOUR FUTURE

SUPPLEMENT FACTS

Incorporating innovative science into the

Serving Size 1 Capsule

Servings Per Container 120

Amount Per Serving


Vitamin D3 (as cholecalciferol)
Marine Lipid concentrate
Omega 3 Fatty Acids:
EPA
DHA
Citrus Bioflavonoids
Purple corn (Zea mays L.) cob extract
Alpha Lipoic Acid
Quercetin (from Dimorphandra mollis fruit extract)
D-Limonene
Rosemary (Rosmarinus officinalis L.) leaf extract
Resveratrol (from Polygonum cuspidatum root extract)
Coenzyme Q10
Lycopene
Astaxanthin (from Haematococcus pluvialis algae extract)

% RENI
50 IU
527.5 mg

150 mg
100 mg
50 mg
33.3 mg
25 mg
18.75 mg
12.5 mg
9.38 mg
7.5 mg
7.25 mg
1.25 mg
0.25 mg

*
*
*
*
*
*
*
*
*
*
*
*

* RENI Value (DV) not established.


RENI Value based on adults age 19-50
Other Ingredients: Capsule (Gelatin, Water).

WARNINGS
Keep out of reach of children. If you are pregnant,
lactating, or taking a prescription medication, consult a
physician prior to using this product. Do not use if safety
seal is broken or missing. Contains fish (anchovies,
sardines, mackerel) and soy.

2015 Nu Skin Enterprises Philippines, LLC Product Information Page www.nuskin.com.ph


003794/1

25%

development of personal care and nutritional


products gives you exclusive access to a
premier anti-aging business opportunity. By
leveraging the growing anti-aging megatrend with
scientifically proven ageLOC products, Nu Skin
empowers you to build and share your business
with others. Experience an opportunity thats
unsurpassed in the anti-aging industry
discover the difference demonstrated today.