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NodavirusDetectedInNorweiganFarmedCod
25August2006

NORWAYNodavirushasbeendetectedforthefirsttimeincodin
Norway.NewresearchresultsatFiskeriforskningcanprovetobe
importantinthefightagainstthevirus.

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Earlierthisweek,theNationalVeterinaryInstituteandthe
NorwegianFoodSafetyAuthorityreportedthatthenodavirus,which
haspreviouslyaffectedbothhalibutandturbotfryinNorway,has
beendetectedforthefirsttimeinNorwegianfarmedcod.
Theviruscancausethediseaseviralnervousnecrosis(VNN)inthe
fishthatbecomesinfected.Theresultcanbereducedappetiteand
highmortality.

Frymostvulnerable
TogetherwithEngineerSaskiaMennenandothers,SeniorScientistAnn
IngerSommerhasspentseveralyearsstudyinginfectionbynodavirusin
halibut,spottedwolffishandcod.Sommersaysthatinthecod,asintheother
fishspecies,thefryaremostvulnerabletothediseaseafterinfectionthrough
thewater.
Testshaveshownthatthesmallestcodfrybecamesickafterinfectionwitha
nodavirusfromNorwegianfarmedcod.Duringthetwomonthtestperiod,56
%ofthecodfrydiedthatweighed0.5gwheninfectedviathewater.
Conversely,thelargerfrythatweighed5gdidnotdieofinfectionviathe
water.Inthisgroup,35%diedofVNNwhentheywereinfectedthrough
injectionofthevirusintothefish.

Hightemperaturecauseshighermortality

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Thelasttestsalsoshowthatwhenthetemperatureinthewaterrises,thereis
apronouncedincreaseinmortalityinthefishthatareinfectedwiththevirus.
Fryweighing5gthatwereinfectedbyinjectionofthevirussuffered60%
mortalityinwaterthatwaskeptataround15degreesCelsius.Incoolerwater,
themortalityratewasmuchlower.
"Thetestsshowthattheinfectedcodisfarmorelikelytodieofthenodavirus
ifthewatertemperaturerises",saysSommer.
So,whatcanbedonetopreventthisvirusfrombecomingabigproblemfor
codfarming?

Usingchallengemodelsinthefightagainstthedisease

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elearning

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TheresearchresultsatFiskeriforskningarethebeginningofachallenge
modelforthediseaseVNNincod,onalevelwiththemodelscientistsatthe
InstitutehavecreatedfortheviraldiseaseIPNinsalmon.
Forexample,suchachallengemodelcanhelpthescientistscreateavaccine
againstVNNincod.Itcanalsobeusedinthecodbreedingprogrammeto
selectthecodfamiliesthatarehereditarilymostresistanttothedisease.
"Whencomplete,themodelwillalsohelpuslearnhowthecodthrivesbestin
farmingconditions.Afishthatthatthrivesalsohasabetterimmunedefence",
saysSommerinclosing.
TheresearchisfinancedbytheResearchCouncilofNorway,Innovation

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5/17/2016

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