Paracetamol

Drug name

Indication

Contraindicatio n
• Contraindicated with allergy to acetaminophen Use cautiously with impaired hepatic function, chronic alcoholism, pregnancy, lactation. • •

Drug Action
Decreases fever by inhibiting the effects of pyrogens on the hypothalamic heat regulating centers and by a hypothalamic action leading to sweating and vasodilation. Relieves pain by inhibiting prostaglandins synthesis at the CNS but does not have antiinflammatory action because of its minimal effect on the peripheral prostaglandin synthesis.

Adverse and Side Effects
• CNS: weakness, fatigue, nervousness, sedation, drowsiness, dizziness, depression, tremor, headache, seizures Dermatologic: pruritus, urticaria, rash GI: Anorexia, nausea, vomiting, constipation, hepatic insufficiency GU: Hematuria, glycosuria, urinary frequency, renal colic, crystaluria,

Nursing Responsibilities
• Assess patient’s fever or pain: type of pain, location, intensity, duration, temperature Assess allergic reactions: rash, urticaria; if these occur, drug may have to be discontinued Assesss for ➢ chronic poisoning: rapid, weak pulse ➢ dyspnea: cold, clammy extremities

Generic name:
Paracetamol •

Relief of mild-tomoderate pain Temporary reduction of fever

Brand Name:
Biogesic

Classification:
Analgesics Antipyretic

report immediately to prescriber.

polyuria Other: weight loss, fever , acidosis

Give with food or milk if GI upset occurs

Route and Dosage:

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