Microbiology of

Disease
Workshop Booklet
2015-2016

Other groups should take relevant notes on the different subject areas. on which you should make brief notes in the space provided below BEFORE the workshop session.” Each group will then put together a 5 MINUTE presentation and elect members of the group to present back to the class.Microbiology of Disease Workshops Workshop 1 Normal microflora and Clostridium difficile Simon Baines Dr Aim  To understand colonisation resistance to Clostridium difficile Learning Outcomes    To understand the factors that influence the human gut microflora composition To understand the factors that may contribute to the development of Clostridium difficile infection in the human gut To discuss strategies that may restore colonisation resistance in the human gut and their potential as treatments for C. difficile infection Workshop structure You will be allocated into groups via StudyNet and will be instructed to read a short piece of relevant scientific literature. Age and the normal microflora Diet and the normal microflora . After a short introduction you will form your allocated groups and discuss in your groups the important points from the scientific literature you have reviewed related to ‘Factors that affect the normal gut microflora in humans.

groups may bring a laptop and prepare slides or alternatively use a flip chart to note down the important points. Please make sure that you attend the workshop you have been assigned to.Stress and the normal microflora Immune status and the normal gut microflora Antibiotics and the normal gut microflora For the presentation. .

Chest X-ray revealed right upper lobe infiltrates. She also had night sweats and fever and felt tired. Despite treatment with erythromycin antibiotic for suspected pneumonia. Learning outcomes The student will be able to understand .treatment and prevention of tuberculosis Workshop Case Study: A 32 year old Hispanic woman presented with a cough for several weeks and a 15 lb weight loss.Workshop 2 Bacteriology Workshop on Mycobacterium tuberculosis Dr Madhu Goyal The aim of this workshop will be to introduce and understand the pathogenesis. Physical examination revealed bilateral rales and lymphadenopathy.diagnosis of the disease . She complained about coughing blood tinged sputum. Other groups should take relevant notes on the different subject areas. You will be allocated into groups via StudyNet and you should read the case study provided in week 10 or 11 on which you should make brief notes in the space provided below BEFORE the workshop session. her fever and cough progressively got worse.the structure of Mycobacterium tuberculosis . diagnosis and treatment of disease caused by Mycobacterium tuberculosis. Each group will then put together a 5 MINUTE presentation and elect members of the group to present back to the class. . After a short introduction you will form your allocated groups and discuss in your groups the important points from the scientific literature you have reviewed related to the case study to answer the questions posed in workshop 1.the types of diseases it can cause .incidence of tuberculosis throughout the world . She had emigrated from Venezuela to UK three years before her illness but she frequently returned to Venezuela to visit relatives.

Q2 How the disease can be diagnosed? .Q 1 What is the rationale for diagnosing tuberculosis.

Q3 What is the pathogenesis of the disease Q4 What is the treatment/s for the disease? .

Q5 What is the epidemiology of the disease? Q6 How can we prevent the disease? .

two or more stages of the viral life cycle are targeted. Viral infections are a major and persistent threat to global health. Anti-viral agents tend to be class-specific rather than virus-specific. Workshop 3 Mycotoxins Dr Avice hall The details of the workshop will be given nearer the time of workshop via studynet. These agents target specific stages of the viral life cycle such as viral entry. prepare brief notes about the anti-viral agents listed below. Effective control of viral infections involves mass immunisation programmes. most of this success has been against viruses that cause acute. self-resolving viral infections. improvements in living conditions and developing new anti-viral treatments. replication and maturation and so a detailed knowledge of the key steps involved in the life cycle is required. By contrast. Prophylactic vaccines have made a significant contribution to the eradication and/or control of many infectious diseases and are one of the greatest triumphs in medical science. groups may bring a laptop and prepare slides or alternatively use a flip chart to note down the important points. Zidovudine. Enfuvirtide. However. Workshop 4 Virology workshop: Anti-viral agents Macmullan Dr Niall The aim of this workshop is to familiarise you with some of the types of anti-viral agents in current use and to promote understanding on the mechanism of action of these compounds. Saquinavir and Oseltamivir. In some instances.For the presentation. . Pay particular attention to the rationale and molecular mechanism of action of each example listed. Anti-viral agents Aciclovir. a single treatment targeting one aspect of the life cycle may be sufficient to control the infection. Please make sure that you attend the workshop you have been assigned to. whereas in the case of HIV infection. chronic viral infections are controlled mainly by therapeutic intervention with anti-viral agents. Exercise Prior to the workshop. Efavirenz.

.Workshop 5 Epidemiology Workshop Naseby Dr David The details of the workshop will be given nearer the time of workshop via studynet.