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  • Dental Caries and Salivary Immunoglobulin A in Down Syndrome Children 2004

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    Rajesh Rathod
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    Dental Caries and Salivary Immunoglobulin a in Down Syndrome Children 2004

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    17 views2 pages

    Dental Caries and Salivary Immunoglobulin A in Down Syndrome Children 2004

    Uploaded by

    Rajesh Rathod
    caries

    Copyright:

    © All Rights Reserved
    Download as PDF, TXT or read online from Scribd
    Flag for inappropriate content
    of 2

    10/5/2016

    DentalcariesandsalivaryimmunoglobulinAinDownsyndromechildren.PubMedNCBI

    PubMed

    Format:Abstract

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    JPaediatrChildHealth.2004SepOct40(910):5303.

    DentalcariesandsalivaryimmunoglobulinAinDownsyndromechildren.
    LeeSR1,KwonHK,SongKB,ChoiYH.

    Authorinformation
    Abstract
    OBJECTIVES: Thisstudyinvestigatedtherelationshipbetweendentalcariesandthesalivary
    StreptococcusmutansspecificantibodiesinDownsyndromechildren.
    METHODS: NineteenchildrenwithDownsyndromeand41normalchildrenaged817yearswere
    selected.Theoralhealthstatus(dentalcariesexperience,pitandfissuredepth,dentalarchspace,and
    SimplifiedOralHygieneIndex)wasexaminedandunstimulatedsalivawascollected.Thetotalsalivary
    immunoglobulinA(IgA)andS.mutansspecificsalivaryIgAconcentrationsweremeasuredusingELISA.
    RESULTS: Thedecayedandfilledsurfaceindexofthedeciduousteeth,andthedecayed,missing,and
    filledsurfacesindexofthepermanentteethinDownsyndromechildrenweresignificantlylower
    comparedtothoseinnormalchildren.ThesalivaryS.mutans(serotypegandc)specificIgA
    concentrationsweresignificantlyhigherinDownsyndromechildrenthaninthenormalchildren.There
    wasnosignificantdifferenceinthetoothcharacteristicsandoralhygienebetweenthetwogroups.
    CONCLUSIONS: ThelowcariesprevalenceinDownsyndromechildrenappearstobeduetoimmune
    protectioncausedbytheelevatedsalivaryS.mutansspecificIgAconcentrations.
    PMID:15367146 DOI:10.1111/j.14401754.2004.00457.x
    [PubMedindexedforMEDLINE]

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    https://www.ncbi.nlm.nih.gov/pubmed/15367146

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    10/5/2016

    DentalcariesandsalivaryimmunoglobulinAinDownsyndromechildren.PubMedNCBI

    https://www.ncbi.nlm.nih.gov/pubmed/15367146

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