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LabCorp

recognizes that pediatricians and pediatric endocrinologists have special needs and
requirements for the laboratory testing of their patients. Age-specific reference intervals and
specimen collection issues are particular concerns in pediatric patient care and evaluation.
Frequently, adult reference intervals are not appropriate for pediatric patients. To assist physicians in treating their pediatric patients, this document lists age-specific reference intervals for
many of the endocrine tests offered by LabCorp. Where available, reference ranges are also
provided by Tanner stage.
LabCorp realizes that pediatric specimen collection can be challenging and is a major concern
for health care providers. It is frequently difficult to obtain substantial volumes of blood or
urine from pediatric patients. For this reason, we have provided an appropriate specimen
volume as well as an analytical minimum specimen volume for each test. The minimum volumes listed in this document represent the analytical minimum specimen required to perform
the test once. This volume does not permit any repeat analysis. It is highly recommended that
the preferred volume indicated below be submitted whenever possible.

Aldosterone (ng/dL) ....................................... 004374

5a-Androstane-3a, .. 17b-Diol Glucuronide ..... 140442

Volume: 0.8 mL (0.3 mL minimum) Serum

Volume: 0.3 mL (0.2 mL minimum) Serum

Age

Male/Female

Age

Male

Female

< 1 yr
1-3 yr
4-7 yr
8-11 yr
12-16 yr

5.0-132.0
5.0-60.0
4.0-76.0
3.0-28.0
1.0-18.0

0-3 yr
4-5 yr
6-7 yr
8-9 yr
10-11 yr
12-13 yr
14-15 yr
16-20 yr
Tanner Stage
I (< 8yr)
I (> 8yr)
II
III
IV
V

< 80
< 70
< 399
< 220
< 311
< 737
131-1395
103-2603

< 60
< 155
< 330
< 140
< 340
78-441
73-760
113-732

<400
<513
<707
94-568
284-1205
103-2630

< 330
< 144
66-174
96-441
79-854
73-732

Aldosterone (µg/24 hours) .......................... 004291
Volume: 0.3 mL (0.1 mL minimum) Urine

Age

Male/Female

0-1 mo
2-11 mo
1-15 yr

1-11
1-22
2 -16

Note: Use plastic transport tubes for all frozen specimens. In addition, to avoid delays in turnaround time when requesting multiple tests on frozen samples, please
submit separate specimens for each test requested.

1

...8 1..9 b2-Microglobulin (mg/L) ...2 mL minimum) Serum Age Male Female 0-5 mo 6-11 mo 1-5 yr 6-9 yr 10-11 yr 12-14 yr 15-17 yr Tanner Stage I (<7 yr) I (>7 yr) II III IV 5-45 5-30 5-45 5-55 10-30 20-85 35-100 5-35 5-25 5-40 5-45 25-80 15-175 55-200 < 35 < 49 < 89 11-91 <219 < 42 < 83 <143 <152 28-252 Angiotensin-converting Enzyme (U/L) .5 mL minimum) Plasma..8 1...... Fractionated (pg/mL) .0 mL minimum) Urine Age 0-23 mo 2-4 yr 5-9 yr 10-19 yr Epinephrine Male/Female < 75 < 57 < 35 < 34 Note: Use plastic transport tubes for all frozen specimens....8-2.5-2. 046557 Volume: 2.. 084152 Volume: 3.....0 Less than 11.4-3...... Frozen Epinephrine Male/Female Age 2-9 days 10 days-2 mo 3 mo-11 mo 12-23 mo 24-35 mo 3-15 yr Age 36-401 55-201 55-438 36-639 18-438 18-456 Norepinephrine Male/Female 2-9 days 10 days-2 mo 3 mo-11 mo 12-23 mo 24-35 mo 3-15 yr 169-1184 372-2081 271-1117 68-1810 186-1472 85-1252 Catecholamines (µg/g creatinine) .0 0..........9 1....7-2. 004705 Volume: 0... In addition...2 mL minimum) Serum/Plasma Age Male Female 0-1 mo 1-6 mo 7-11 mo 1-3 yr 4-6 yr 7-9 yr 10-12 yr 13-15 yr 16-18 yr 1..... 316203 Volume: 10 mL (4...1 0...0 mL minimum) Frozen Plasma Age Range 0-1 mo 2-11 mo 1-18 yr Less than 20.9-3........4 0..3 0.2 mL (0....2 mL minimum) Serum Age Male/Female 0-2 yr 3-7 yr 8-14 yr >14 yr 5-83 8-76 6-89 8-52 Antidiuretic Hormone..5 mL (0.. to avoid delays in turnaround time when requesting multiple tests on frozen samples..2 0...0 mL (1....8-1...8 0....1 mL minimum) Frozen Plasma Age Male Female < 1 yr 1-2 yr 3-4 yr 5-6 yr 7-8 yr 9-10 yr 11-12 yr 13-14 yr 15-16 yr 47-157 26-99 27-101 34-116 34-108 39-139 20-166 11-195 23-170 57-109 26-129 31-95 33-105 21-133 29-157 42-154 < 113 < 69 Catecholamines....9 0.....7-1... please submit separate specimens for each test requested...7-4..6-1.. 010116 Volume: 0.2 Less than 6.0-2..0 mL (1.3 0..0 0....8 0....5 1.. 2 .....7-1...6-2.7-2..8-1. ADH (pg/mL) .....Androstenedione (ng/dL) ..3 mL (0..3 0..9 Bone-Specific Alkaline ..7-2...... 010181 Volume: 0.. 513002 Phoshphatase (µg/L) Volume: 0.2 0.........5 mL (0...7 0..7-1.6-4....0-3...

..5 mL (0... 004101 Volume: 0....4 mL minimum) Serum Age Male Female 1-7 days 8-15 days 1-3 yr 4-6 yr 7-8 yr 9-10 yr 11 yr 12 yr 13 yr 14 yr 15 yr 16 yr 17 yr 18-19 yr Tanner Stage I II & III IV V 91-376 37-224 < 30 < 186 < 94 < 75 < 152 < 344 < 242 < 286 59-310 47-357 102-341 108-441 73-367 44-247 < 79 < 38 < 68 < 160 < 98 < 177 < 167 32-301 39-288 58-354 97-399 145-395 < 87 < 151 75-282 121-368 < 65 < 175 57-230 76-378 Note: Use plastic transport tubes for all frozen specimens.1 mL minimum) Serum Age Male Female 0-5 yr 6-7 yr 8-9 yr 10-11 yr 12-14 yr Tanner Stage I II III IV V 26-72 29-66 53-135 183-383 240-520 19-42 73-165 74-180 234-529 224-611 31-345 110-495 170-585 160-640 250-900 31-345 150-570 200-600 200-780 215-850 Dehydroepiandrosterone (DHEA) ......6 2.9 2.4 3......7-13.. 3 .....4-28..5-28.... Urinary Free by HPLC (µg/24 hr) . Frozen Age Male/Female 0-9 yr 10-16 yr 0. please submit separate specimens for each test requested...6 2...6 0......4-16.3 mL (0.7 Cortisol.6-19..Age Norepinephrine Male/Female 0-23 mo 2-4 yr 5-9 yr 10-19 yr < 420 < 120 < 89 < 82 Dopamine Age Male/Female 0-23 mo 2-4 yr 5-9 yr 10-19 yr < 3000 < 1533 < 1048 < 545 Cortisol (µg/dL) .3 0........8 2. to avoid delays in turnaround time when requesting multiple tests on frozen samples......3 1..5-22. 004051 Volume: 0..7-15......0 mL (0.... In addition.9 2.................. 004697 Sulfate (µg/dL) Volume: 1....3 mL minimum) Serum Age Male Female 5th day 2 mo-13 yr 14-15 yr 16-18 yr Tanner Stage II-III IV-V 0...4-3... 010108 Volume: 1...0 mL (0.....0-3..4 mL minimum) Serum.6-19..0 mL minimum) Urine Age Male/Female 2-11 yr 12-16 yr 1-21 2-38 C-Peptide (ng/mL) ...9 2.5-15...4-28....3 Dehydroepiandrosterone (DHEA) (ng/dL) .... 004432 Volume: 15 mL (5.4-22...2 4.8 2...4-22..

7-22.....2 7.0 mL minimum) Urine Age Male Female 8-11 yr 12-18 yr 7.4 2..0 2...4-1..0 <3..0-65................ Total (pg/mL) .4-7.3 mL minimum) Serum Age Male Female 1-6 yr 7-10 yr 11-12 yr 13-15 yr 16-17 yr Tanner Stage I II III IV V <15 <15 <40 <45 10-50 <15 <70 10-300 10-300 10-300 3-15 3-10 5-15 3-40 15-45 5-10 5-115 5-180 25-345 25-410 Estrogens.4 mL minimum) Serum Age Male Female 0-23 mo 2-5 yr 6-10 yr 11-20 yr Tanner Stage I & II III & IV V 0.2 1. 511105 Cross-Links (nmol Dpd/mmol creatinine) Volume: 10 mL (1.0 4...0-22..5-21.2-14..8 1..1 3.0 24.2-15.8 mL (1.7-6.6 0.........0 8.7 0....0-20..9 3.......8 0.2 *This test may be considered by Medicare and other carriers as investigational and.8 mL (0..9-8....0 4....0 0.0-9..1-8.. may not be payable by the carrier as a covered benefit for patients.........5 mL minimum) Serum Age Male Female Newborn Prepubertal Tanner Stage I II III IV V Adult 5. therefore.0 <15..0-60....... 004549 Volume: 2.. 140368* Volume: 1.0-13..........4-1. 140244 Volume: 0.0 3..6 Dihydrotestosterone (ng/dL) ..0 30..0-18... to avoid delays in turnaround time when requesting multiple tests on frozen samples.4 1. 004309 Volume: 1..7 1..0 3...8-20.3-4.....4-8. 4 .....0-85........0-33.0 mL (0. Note: Use plastic transport tubes for all frozen specimens...5 1..1 0..9 2.4-4.2 mL minimum) Serum Age Male Female 0-5 yr 6-7 yr 8-9 yr 10-11 yr 12-14 yr Tanner Stage I II III IV V 18-53 17-48 20-54 21-49 17-44 19-46 17-44 31-70 28-68 57-140 5-17 10-25 15-25 15-45 20-45 4-29 10-33 15-43 16-77 29-105 Follicle-stimulating Hormone (mIU/mL) ...0 <3...5 2.4-24.. 140277 Volume: 0..1 0......0 <3.6 0......Deoxypyridinoline (Dpd) .0-19...4-3.0-12...0 5..0-7..6-20..7-17.5 Estradiol (pg/mL) ....7 0.3 mL minimum) Serum Age Male Female 1-3 yr 4-6 yr 7-9 yr 10-12 yr 13-15 yr 1.9 1....8 mL (0.....0 Erythropoietin (mIU/mL) ..2 0....0-17..0-52...4-8.0 7..1 0........ In addition......4-2..0-13..6 1..... please submit separate specimens for each test requested..1-15.2 mL (0.0-14...4 1..............5-6... 004564 Volume: 0....0 22.1-9.............1 mL minimum) Serum Age Male Female 0-10 yr Tanner Stage I II III IV V 0-25 0-25 10-38 17-45 22-55 27-80 25-80 10-46 22-63 24-110 40-180 60-280 Estrone (pg/mL) .0 <3.4 mL (0.

.5 Insulin Autoantibodies (U/mL) ....5 mL (0.0 17-Hydroxyprogesterone (ng/dL) .....8 mL (0....0 6.8-5.0 *This test may be considered by Medicare and other carriers as investigational and..Gastrin (pg/mL) ......... 316205 (mg/g creatinine) IA2 Autoantibodies (U/mL) .................8 3...02 mL Serum Male & Female < 1........5 mL (1.. to avoid delays in turnaround time when requesting multiple tests on frozen samples.2 mL (minimum) 0... 120246 Volume: 10 mL (4......3 mL minimum) Serum Tanner Stage Male/Female I II & III IV & V 2..........2-16.2 mL minimum) Serum Male & Female less than 1.........3 mL (0.8-23..7 3...3-35..... 004333 Volume: 0............3 mL minimum) Serum..0 mL (0.9 12. 004275 Volume: 0............ 143008* Autoantibody (U/mL) Volume: 0.......3 mL minimum) Serum Age Male/Female 1 day 1 wk 1-12 mo 1 yr to Adult 5-53 5-27 2-10 Less than 5...........2 2.. 141598 Volume: 0... 5 .. Fasting (µIU/mL) . Frozen Volume: 2.. therefore...0 8..3-22... 141531 Volume: 0...7 1......2-31..........3 mL minimum) Urine Age Male/Female 3-8 yr 9-12 yr 13-17 yr 1... may not be payable by the carrier as a covered benefit for patients......... Note: Use plastic transport tubes for all frozen specimens......75 Insulin....0 8.5 mL (0.... 140715 Volume: 0.0 mL (0......5 8.....4-44..1 mL minimum) Serum Male & Female less than 0. In addition.8 mL (0...4-32.....1 mL minimum) Serum/Plasma Age Male/Female Age Male Female 69-190 55-186 2-168 3-117 1-125 < 1 yr 1-5 yr 6-12 yr Tanner Stage II-III IV-V 14-77 12-103 31-186 62-287 10-47 11-141 20-363 32-297 58-450 53-542 0-1 mo 2-22 mo 22 mo-16 yr (fasting 3-4 hr) 22 mo-16 yr (fasting 5-6 hr) 22 mo-16 yr (fasting >8 hr) Glutamic Acid Decarboxylase ... please submit separate specimens for each test requested......5-23.... 004390 17-Hydroxypregnenolone (ng/dL) ....4-8.....5 U/mL Growth Hormone (ng/mL) .........6 5-Hydroxyindoleacetic Acid .0 mL minimum) Urine Age Male/Female 0-2 mo 3-11 mo 12-23 mo 2-4 yr 5-9 yr 10-15 yr 11...... 004713 Volume: 1........6-15..0 Volume: 1..........5 mL minimum) Serum Age Male Female < 1mo 1-5 mo 6-11 mo 1-3 yr 4-6 yr 7-9 yr 10-12 yr 13-15 yr 16-18 yr 53-186 35-157 6-40 2-19 1-34 1-45 1-34 23-82 8-100 17-204 25-110 5-47 3-51 4-34 4-44 3-33 2-72 3-91 Homovanillic Acid (µg/mg creatinine) .....2-13..

3 .5.1041 380 ...674 211 .6-7..3 0.9-3.4 *This test may be considered by Medicare and other carriers as investigational and....Insulin-like Growth Factor I (ng/mL) .....3..6 1..3 ..3...7 .3.. Fractionated (µg/24 hr) .5 ..5.1102 398 .1 1. 004283 Age Male/Female Newborn 0-2 yr 3-4 yr 5-6 yr 7-8 yr 9-10 yr 11-12 yr 13-14 yr 15-18 yr 78 .5.. please submit separate specimens for each test requested. 010363 17-Ketogenic Steroids (mg/24 hr) .5 1.6-6.1-4.0-0..1207 386 .4.1 0.....8 ..1 2. therefore.....6 .....0 1........5 mL (0.4 ...0 Metanephrines.4 1.6..9 1...9 . 004010 Volume: 0..8 0..4. to avoid delays in turnaround time when requesting multiple tests on frozen samples......0 Volume: 0.1 0. In addition.....0 0.5-1.3 1.7 .3-4.3 mL minimum) Serum Age Male Female 0-23 mo 2-10 yr 11-20 yr Tanner Stage I II III IV & V 0..6..8 1...5..9 .6...1122 342 .8 0...4 1..0 0.0-0.5-9.8 1.8 .7 ......2 mL minimum) Serum Age Male Female 0-4 yr 5-9 yr 10-11 yr 12-13 yr 14-16 yr <2 <3 1-5 1-6 3-13 <2 <3 1-5 1-6 2-8 Luteinizing Hormone (mIU/mL) .1140 455 ..9 .. 6 ...574 206 .3 mL (0.0 1.5 0.... Note: Use plastic transport tubes for all frozen specimens.0 1..1.. 141770* Volume: 0..2 .0-3.3.....0-3..2-9..727 281 ...4 mL (0. 004234 Volume: 25 mL (10 mL minimum) Urine Age Metanephrine Normetanephrine 3-8 yr 9-12 yr 13-17 yr 5-113 21-154 32-167 13-252 32-346 63-402 Neopterin (ng/mL) ....5.....7 1.9 .. may not be payable by the carrier as a covered benefit for patients.0 .. 140335* Volume: 0...5 0...... 004028 Volume: 25 mL (15 mL minimum) Urine 109-485 174-512 230-818 396-776 402-839 128-470 186-695 292-883 394-920 308-1138 Insulin-like Growth Factor II (ng/mL) .1 1.2..5-15..0 17-Ketosteroids (mg/24 hr) .4 mL (0...6.5 0....6 .5 .8 mL (0..1 mL minimum) Serum Age Male Female 0-1 yr 2-3 yr 4-5 yr 6-7 yr 8-9 yr 10-11 yr 12-13 yr 14-15 yr 16-17 yr 18-20 yr 0..5 0..2 ..2 mL minimum) Serum Volume: 12 mL (10 mL minimum) Urine Age Male Female 2 mo-5 yr 6-8 yr 9-11 yr 12-15 yr 16-24 yr Tanner Stage I II III IV V 17-248 88-474 110-565 202-957 182-780 17-248 88-474 117-771 261-1096 182-780 Age Male/Female 0-11 mo 1-10 yr 11-14 yr <1.4 1...0-0...3 1.6.1 .....2...9 0.0 <12.0 0.....3....3 0. 140152 Protein 3 (mg/L) Volume: 0..1230 Insulin-Iike Growth Factor-binding .2 mL minimum) Serum Age Male/Female 0-18 yr 0..6 0...0 <5....5-5.

5 mL (0.5 mL (0...6-13.6-16.. 015610 Volume: 1.........9-11..... 120089 Volume: 1.....4-37.5 0.7-81..3 Serotonin (ng/mL) ...9 1. Intact (pg/mL) ..3 mL minimum) Serum Age Male Female 1-10 yr Tanner Stage I II III IV V < 0.....1 mL minimum) Plasma...9 2. Frozen Age Male/Female 0-18 yr 113-431 Note: Use plastic transport tubes for all frozen specimens... 004317 Volume: 0.5 mL (minimum) 0....2 0.5 mL (1. Frozen Age Male Female 6 yr 7 yr 8 yr 9 yr 10 yr 11 yr 12 yr 13 yr 14 yr 15 yr 16 yr 17 yr 18 yr 19 yr < 28 < 41 < 54 < 48 < 47 < 76 < 126 < 99 < 116 < 115 < 70 < 41 < 38 < 28 < 52 < 53 < 54 < 46 < 61 < 83 < 94 < 96 < 75 < 32 < 32 < 26 < 17 < 16 Parathyroid Hormone (PTH).....2 0..... Frozen Age Male/Female 2-20 yr 9-52 Pregnenolone (ng/dL) ............5-3.1 0....5-5....0-14......1 0....9 1.....0 1.3-13................0 0.....6 mL Blood....5 < 0..3 < 0....... 002006 Volume: 2.8 < 0..4 Renin.3 < 0...........3 mL minimum) Serum......6 0.....6 0...9-12.........................3 < 0... 142026 Volume: 1...... 140707 Volume: 2.. Active (uU/mL) ..0 mL (0.N-Telopeptide Cross-links (NTX) ..5 < 13... 010249 Volume: 1....0-6.0 mL (0...5 < 1..8-16.6 3..3-12.3-28.......5 mL (1.....3-95..4 mL minimum) Serum......5 < 4.0-17..2-29... In addition...9 1..2 1....0 mL (0.5 Prolactin (ng/mL) ....1 mL minimum) Serum/Plasma Age Male Female < 1 yr 1-5 yr 6-12 yr Tanner Stage II & III IV-V 10-137 10-43 15-45 18-87 19-48 17-38 15-84 20-77 10-45 11-50 Progesterone (ng/mL) .... 511097 (mM BCE/mmol creatinine) Volume: 1. 7 . to avoid delays in turnaround time when requesting multiple tests on frozen samples..0-35..3 mL minimum) Urine Tanner Stage Male Female I II III IV V 55-508 21-423 27-462 <609 <240 6-662 193-514 13-632 <389 <132 Osteocalcin (ng/mL) .... Frozen Age Male/Female 0-1 mo 2-11 mo 1-3 yr 4-5 yr 6-10 yr 11-15 yr 2......0 0...9 0........5 mL minimum) EDTA Plasma Age Range 1-6 yr 7-12 yr 13-17 yr 4-89 3-66 2-37 Renin Activity (ng/mL/hr) .....2-9.....0 2.9 1........0 1.9-9.0 mL (0........3 mL minimum) Serum Age Male Female <1 mo 1-11 mo 1-3 yr 4-6 yr 7-9 yr 10-12 yr 13-15 yr 3.......... 004465 Volume: 0.....2-0.....7-11..5 < 0........... please submit separate specimens for each test requested.......

0 0..9 1.5-0...5 0. may not be payable by the carrier as a covered benefit for patients..33-0..13 0.. Note: Use plastic transport tubes for all frozen specimens..9 1.7 2.52 0..09 0..7 mL minimum) Serum Age Free Testosterone (ng/dL) Male Female Cord Blood 1-15 days 1-2 mo 3-5 mo 6-7 mo 6-9 yr 10-11 yr 12-14 yr 15-17 yr 0.04-0. Platelet (ng/109 platelets) .. 042846* Volume: 0.00-15.07-1.3 mL minimum) Serum Age Male Female 1-5 mo 6-11 mo 1-5 yr 6-7 yr 8-10 yr 11-12 yr 13-15 yr Tanner Stage I II III IV V 1-177 2-7 0-10 0-20 0-25 0-350 15-500 1-5 2-5 0-10 0-10 0-30 0-50 0-50 2-23 5-70 15-280 105-545 265-800 2-10 5-30 10-30 15-40 10-40 Testosterone. In addition......0 0. 004226 Volume: 0.0-1. 082016 Volume: 0.....0-3. Quantitative (ng/mL) .10-0.52 0.40 0.48 0..80 0.8 mL (0.50-2...8 mL (0. 120196 See Directory of Services and Interpretive Guide for specimen requirements Age Male/Female 0-19 mo 20 mo .01-0.3 mL minimum) Serum Term Infants Male/Female Cord Blood 1 day 10 day 5-65 6-93 9-148 Premature Infants (27 to 31 weeks) 1 day 3 day 30 day 107-395 49-163 17-63 *This test may be considered by Medicare and other carriers as investigational and.9-1.....01-0.20 0.3 mL (0.52 Percentage of Total Testosterone Age Male Female Cord Blood 1-15 days 1-2 mo 3-5 mo 6-7 mo 6-9 yr 10-11 yr 12-14 yr 15-17 yr 2.10-0.15 yr 164-424 537-903 Sex Hormone-binding Globulin (nmol/L) ...0 1.57 0.8 0.02-0...5-1.0-1. Free by Ultrafiltration .9 Thyroglobulin...90 0....10-0.25 0. to avoid delays in turnaround time when requesting multiple tests on frozen samples..40-1..15-3.1 0.. 8 ... therefore.7 0..14-15.9 1.8-1..06 0.1 mL minimum) Serum Age Male Female 0-1 mo 1-12 mo 1-3 yr 4-6 yr 7-9 yr 10-12 yr 13-15 yr 16-18 yr 11-71 60-209 42-156 39-146 38-114 32-93 13-93 11-54 12-51 50-181 51-158 48-142 31-103 20-100 17 -77 9-75 Testosterone.60 8.03-0.60 0..8-2...3-3...4-1.4-0.0-1. 081786 with Total (ng/dL) Volume: 1...4-1..9-1.Serotonin...0-1..4 1..9-1.4 0..8 mL (0.9 0..4-1....32 0.1 0.11 0.10 0..0-4......7 1. please submit separate specimens for each test requested. Total (ng/dL) .06-0.05-0...01-0.8 0..

..4-6....48-2.7 1.5 3.9 2..9-13.5-6..... In addition.....0-13.79-1.3-21....59 0.....9-21..5-5. please submit separate specimens for each test requested...9 7.4 1..1-5.8-2.0-6.10 0...0 2.49 0...3 0...93 0...68 0. 004259 Thyroxine-binding Globulin (µg/mL) ...8-11.5 6..55-7.2 2.....0 2.7 7.6 6.. 001735 Volume: 0....1 5.4-5...46-8. 010389 Volume: 0.4-13.93 0. 9 .1-12..53 0..4-4.82-1.8 mL (0..8-11..........76-2...2 Triiodothyronine (T3).3 mL minimum) Serum Age Male Female 1-30 days 1 mo-5 yr 6-18 yr 0..3 mL minimum) Serum Age Male Female < 1 mo 1-11 mo 1-3 yr 4-6 yr 7-12 yr 13-15 yr 5. Free (pg/mL) ....3 mL (0...0 3.58 0.1 7.80-2....8 mL (0..36-5.44 Triiodothyronine (T3)..7 2.. Free by Equilibrium .5 2.9-6..81-1..... Direct (ng/dL) .0 Thyroxine (T4)..7 2..8 mL (0..3 mL minimum) Serum Age Male Female 1-3 days 4-30 days 1-11 mo 1-5 yr 6-10 yr 11-15 yr 16-18 yr 1.5-5.. Reverse (pg/mL) ..Premature Infants (31 to 34 weeks) 1 day 10 day 30 day 7-12 yr 13-18 yr 147-277 32-112 19-51 20-50 9-27 Thyroid-stimulating Hormone (µIU/mL) .1-14..1-12.8 1.0 6.10 0.7-6.37-6..72-13.00 0.90-1.. Free.4-5..9 3..92-1.2-14.32 0.......7-13.0-6..10 0.2 mL minimum) Serum Age Range Birth-4 days 2 wk .80 Thyroxine (T4) (µg/dL) . 141002 Dialysis (ng/dL) Volume: 0. 002212 Volume: 0..61-1.83-1.....78 0.3 mL minimum) Serum Age Male Female 1-11 mo 1-3 yr 4-6 yr 7-12 yr 13-18 yr 16-33 16-32 17-30 17-29 13-26 18-32 19-34 18-31 15-29 14-29 Volume: 0.2 Thyroxine (T4).88-1..5 4..72 0... 002188 Volume: 0..20 yr 2.4 4..88-1.8-5.00 0.....5 6.1 6..57 0..5 mL (0. to avoid delays in turnaround time when requesting multiple tests on frozen samples....8 mL (0.5 mL (0....52-16.2 mL minimum) Serum Age Male/Female 1-4 yr 5-9 yr 10-15 yr 150-710 170-790 190-880 Note: Use plastic transport tubes for all frozen specimens.84 1. 001149 Volume: 0.3 mL minimum) Serum Age Male Female 0-1 mo 2-11 mo 1-5 yr 6-10 yr 11-15 yr 16-18 yr 15-210 95-275 80-253 96-232 73-199 69-201 15-200 50-264 126-258 104-227 96-211 91-164 Triiodothyronine (T3).92-1..2-5...02-1..3 mL minimum) Serum Age Male Female 1-3 days 4-30 days 1-11 mo 1-5 yr 6-10 yr 11-15 yr 16-18 yr 0...8 mL (0..6-5. (ng/mL) ..00 0. 001974 Volume: 0.

to avoid delays in turnaround time when requesting multiple tests on frozen samples...0 0-8..8 mL (0.......2 Vitamin D.3 0-8.... 123208 (mg/g creatinine) Volume: 10 mL (4 mL minimum) Random Urine Age Male/Female 0-1 yr 2-4 yr 5-9 yr 10-19 yr 0-18........... In addition.8 0-11...... 10 ..2 mL minimum) Serum Age < 1 mo 1-11 mo 1-3 yr 4-12 yr 13-18 yr Age < 1 mo 1-11 mo 1-3 yr 4-12 yr 13-18 yr Summer Ranges Male 11-44 26-48 12-60 9-49 9-41 Winter Ranges Male 8-38 13-68 16-51 11-47 6-39 Female 11-41 23-62 18-62 7-48 7-38 Female 6-42 18-48 17-53 14-40 6-28 Note: Use plastic transport tubes for all frozen specimens.. 081950 Volume: 0....3 mL (0.. Uptake (%) .... 25-Hydroxy (ng/mL) .........3 mL minimum) Serum Age Male Female 0-11 mo 1-3 yr 4-6 yr 7-12 yr 11-15 yr 16-18 yr 23-34 24-35 24-34 24-33 25-37 24-38 23-36 24-36 24-35 22-35 23-37 23-35 Vanillylmandelic Acid (VMA) ......... please submit separate specimens for each test requested.. 001156 Volume: 0....Triiodothyronine (T3).....

Aldosterone. 1986. 3rd ed. Urine Meites S. Control of plasma aldosterone in infancy and childhood. C-Peptide. 13:285-291. ed. 30:349-356. Reference (Normal) Values. Saunders Company.B. 1993. 1993. Pediatric reference ranges for B2-microglobulin and ceruloplasmin. Androstenedione Soldin SJ. eds. Lashansky G. Tietz NW. 1976. Clin Biochem. 31:525-529. Plasma adrenal and gonadal sex steroids in human pubertal development. 3rd ed. Serum bone alkaline phosphatase isoenzyme levels in normal children and children with growth hormone (GH) deficiency: A potential marker for bone formation and response to GH therapy. Pediatric Clinical Chemistry. Beckerhoff R.References Aldosterone. Saunders Company. Rauh W. 42:468-476. Bone-Specific Alkaline Phoshphatase Tobiume H. Schärer K. 1975. Wiedmann G. Blood and urinary aldosterone levels in normal neonates. Pediatric Reference Ranges. J Clin Endocrinol Metab. Bailey J. Antidiuretic Hormone Rascher W. 88:57-63. Philadelphia: W. 1981. Saenger P.17ß-Diol Glucuronide 5α α -Androstane-3α Rittner HL. Racadot A. Clinical Guide to Laboratory Tests. et al. et al. et al. 1997. Albertini M.and sex-related changes after adrenocorticotropin stimulation. Pediatric Clinical Chemistry. Brandeis WE. Cathecholamines. et al. Cheng MH. 1986. 1997. Elevation of serum angiotensin-converting enzyme (ACE) level in sarcoidosis. J Edocrinol Invest. α . Am J Med. Serum Candito M. Angiotensin-converting Enzyme Tietz NW. Establishment of reference ranges for cortisol in neonates. Watson P. Serum Ratzmann KP. Lee PDK. 1995:54. 1989:45. 3rd ed. eds. Cheng MH. Normative data for adrenal steroidogenesis in a healthy pediatric population: Age. Cheng MH. Blum WF. 1989:56. 1995:195-196. Loeuile GA. Washington. Serum Meites S. 1991. Urine Soldin SJ. et al. Pediatrie. Strese J Kohnert DK. 617:304-307.75:111-117. Hida S. Developmental patterns of serum 3 alpha-androstanediol glucuronide. et al. High performance liquid chromatographic analysis of urinary catecholamines employing amperometric detection: Reference values and use in laboratory diagnosis of neural crest tumors. Saunders Company. Clinical Guide to Laboratory Tests. Hicks JM. Vasseur P. Lieberman J. Stark P. Urine Tietz NW. Buffone GJ. 3rd ed. Reference (Normal) Values. 43:S199. DC: AACC Press. 1976. Clin Chem. Reference (Normal) Values. 3rd ed. DC: AACC Press. et al. 36:335-344. β 2-Microglobulin Soldin SJ. 1995:174. 59:365. J Clin Endicrinol Metab. ed. Buffone GJ. 11 . Age-dependent relationship of fasting C-peptide concentration and insulin secretion in non-obese subjects with normal glucose tolerance. Beatey J. 1995: 30. DC: AACC Press. Exp Clin Endocrinol.B. infants and children. children and adolescents. Plasma catecholamine levels in children. De Peretti E. Washington. 3rd ed. Pediatric Clinical Chemistry. Washington. DC: AACC Press. Cortisol. eds. Cortisol. Philadelphia: W. Fishman K. infants. et al. Leumann EP. Clinical Guide to Laboratory Tests. Meites S. Kanzaki S. ed.82(7):2056-2061.B. Helv Paediatr Acta. Determinants of plasma arginine-vasopressin in children. Forest MG. J Clin Endocrinol Metab. J Chromatogr B Biomed Sci Appl. Eur J Clin Chem Biochem. Serum Jonetz-Mentzel L. Vandewalle B. 1997. Dehydroepiandrosterone (DHEA) Ducharme JR. Philadelphia: W. eds. Hicks JM. Lam G. Politano S. et al. et al. Buffone GJ. Huber K-H. Cathecholamines. 20:245-250. Acta Paediatr Scand. Pollard A. et al. 1989:45-46. 73:674-686. Washington. 1980.

Philadelphia: W.73(3):674-686. 1999. Williams AJK. 12 . Pediatric Reference Ranges. 1997:68.and sex-related changes after adrenocorticotropin stimulation. 1995:300. Saunders Company. Hicks JM.B. et al. Pediatric Clinical Chemistry. DC: AACC Press. J Clin Endocinol Metab. et al. et al. Brugnara C. Growth hormone binding protiens and various forms of growth hormone: Implications for measurements. Pediatric Clinical Chemistry. J Pediatrics. DC: AACC Press. ed. ed. 2000. 34:312-318. J Clin Endicrinol Metab.Dehydroepiandrosterone Sulfate (DHEA-S) Kühnel W. Insulin. 1995:220. 1977. Acta Paediatr Scand Suppl. 1995:248. et al.B. Los Angeles.B. Buffone GJ. Clin Chem. Clinical Guide to Laboratory Tests. Pediatric Reference ranges for 17 alpha-hydroxy progesterone. 1989:131. ed. Serum gastrin levels in infants and children. 42:468-476. Estrogens. Soldin SJ. Evaluation of the Technicon Immuno I Random Access Immunoassay Analyzer and calculation of pediatric reference ranges for endocrine tests. Philadelphia: W. 1995. Cheng MH. Gunter KC. Tietz NW. 50:782-785. Immulite and Immulite 2000 Reference Range Compendium. 370:72-80. Saunders Company. 3rd ed. 1972. Philadelphia: W. 2nd ed. et al.65:121-124. 3rd ed. Cheng MH. Bremond A. Philadelphia: W. 1989:123. 1991. 17-Hydrox ypregnenolone Lashanski G. Reference (Normal) Values. Plasma adrenal and gonadal sex steroids in human pubertal development. The urinary excretion of deoxypyridinium cross-links is higher in diabetic than in nondiabetic adolescents. Burrington JD. Odell WD. 28:181-185. Gastrin Meites S. [DPC Technical Report] Deoxypyridinoline (Dpd) Cross-links Bjorgaas M. Follicle-stimulating Hormone (FSH) Murthy JN. Tietz NW. Pediatric Reference Ranges. Arch Disease Childhood. Clinical Guide to Laboratory Tests. 68:932-937. Clinical Guide to Laboratory Tests. Philadelphia: W. T-uptake and ferritin. eds. Normative data for adrenal steroidogenesis in a healthy pediatric population: Age. DC: AACC Press. Saenger P. Clin Biochem. progesterone. 3rd ed. Hopper K. and dehydroepiandrosterone sulfate concentrations during childhood. ed. et al.B. LH. Fasting Smith P. eds. insulin-like growth factor I. Morris CL. Baumann G. Washington. Bailey J. 126:601-603. J Clin Endocrinol Metab. Tietz NW. 1976. Burke G. Homovanillic Acid (HVA) Tuchman M. Glutamic Acid Decarboxylase Kronus (kit manufacturer) Directional Insert. Dunger DB. 75:324-328. Washington. 3rd ed. Pediatrics. 1995. DC: AACC Press. 2nd ed. Saunders Company. 1975. Dihydrotestosterone Tietz NW. Total Tietz NW. Clinical Guide to Laboratory Tests. Erythropoietin Krafte-Jacobs B.B. Pediatrics. Williams J. 3rd ed. Buffone GJ. Ramnaraine ML. Sann L. 3rd ed. Clinical Guide to Laboratory Tests. Growth Hormone Tietz NW. Relationship between insulin. Hicks JM. Janik JS. Beatey J.B. Value of random urinary homovanillic acid and vanillylmandelic acid levels in the diagnosis of and management of patients with neuroblastoma: Comparison with 24-hour urine collections. 17-Hydrox yprogesterone Soldin SJ. 1995:222. 3rd ed. 1990. Estrone Meites S. ed. 41:S92. Chayvialle JAP. 1995. Clinical Guide to Laboratory Tests. Plasma erythropoetin reference ranges in children. Soldin SJ. Abraham GE. et al. Saunders Company. De Peretti E. 5-Hydrox yindoleacetic Acid Soldin SJ. puberty and adult life. Fishman K. Swerdloff RS. Estradiol Soldin SJ. Calif: Diagnostic Products Corporation. 3rd ed. Akbar AM. et al. Saunders Company. Lambert R. ed. Serum gastrin level in early childhood. eds. Reference (Normal) Values. Washington. Washington. Johnsen HJ. 1995:216. 60:60-64. 1997:89. Simultaneous radioimmunoassay of plasma FSH. Calcif Tissue Int. 1995:202-203. Haug E. 17-hydroxyprogesterone. 1985. Forest MG. Philadelphia: W. J Clin Endocrinol Metab. 1989. and estradiol-17beta during the menstrual cycle. Ducharme JR. Saunders Company. eds.

17-Ketosteroids Tietz NW. 1995. 1995. Serotonin. 13 . Whole Blood Goldsmith BM. Determination of neopterin in serum and urine. Clin Chem. 1995:410. 1988. 3rd ed. Urinary markers of bone turnover in healthy children and adolescents: Age-related changes and effect of puberty. ed.27(4):316-317. et al. Determination of reference values for serotonin concentration in platelets of healthy newborns. 3rd ed. Reference (Normal) Values. Philadelphia: W. Insulin-like Growth Factor-binding Protein 3 Nichols Institute Diagnostics (kit manufacturer) Directional Insert. Renin Activity Tietz NW. TSH. Hartwell D. Metanephrines Soldin SJ. 3rd ed. Platelet Flachaire E. 1995:380. 3rd ed. Washington. 1998. T-uptake. 43:S200. 36:2117-2120. Washington. Osteocalcin Johansen JS. 1995:124. 17-Ketogenic Steroids Tietz NW. 1997. Dimartino-Nardi J. free T4.67(2):273-278. Hicks JM. et al. Pediatric Reference Ranges. Philadelphia: W.B. Buffone GJ. DC: AACC Press. Clinical Guide to Laboratory Tests. J Clin Endocrinol Metab. Pediatric reference ranges for prolactin. 3rd ed. 1995:578. Saunders Company. DC: AACC Press. 1997:119. Testosterone. Godwin ID. Clinical Guide to Laboratory Tests. 63:369-374. eds. Cheng MH. Berthier A. Saunders Company. height. Beatey J. T4. et al. Clinical Guide to Laboratory Tests. ed. Philadelphia: W. Progesterone Tietz NW. Pediatric reference ranges on the Abbott Imx for FSH.B. Bichler A. 1990. 38:959. DC: AACC Press. 3rd ed. et al. Serum bone Gla-protein as a marker of bone growth in children and adolescents: Correlation with age. Philadelphia: W. eds. Intact Soldin SJ et al. 1989:247. Normative data for the steroidogenic response of mineralocorticoids and their precursors to adrenocorticotropin in a healthy pediatric population. Total Soldin SJ. Neopterin Werner ER. Morales A. 33:62-66. Prolactin Cook JF. et al. 3rd ed. Luteinizing Hormone (LH) Soldin SJ. eds. Tietz NW. Clinical Guide to Laboratory Tests. Clin Chem. Saenger P. Saunders Company. Pregnenolone Lashanski G. Tietz NW. ed. LH. 1992. Clinical Guide to Laboratory Tests. Pediatric Clinical Chemistry. 28:603-606. Saunders Company. ed.B. Philadelphia: W.B. Clinical Guide to Laboratory Tests. Parathyroid Hormone. Yatscoff RW. Calcif Tissue Int. and serum testosterone. ed. Saunders Company. IgE and ferritin. Sex Hormone-binding Globulin Hicks SJ. 19:359-363. Proverbio MC. DC: AACC Press. Philadelphia: W. et al. Pediatric reference ranges for sex hormone binding globulin. Prinster C. prolactin. Determination of a reference range for whole blood serotonin in a pediatric population using high pressure liquid chromatography with electrochemical detection. free T3. 1992. Clin Biochem. Hicks JM. Saunders Company. Meites S. Clin Chem.Insulin-like Growth Factor I (IGF-I) Nichols Institute Diagnostics (kit manufacturer) Directional Insert. Watson P. Pediatric Reference Ranges. Serotonin. Beney C. Renin Active Coates JE. 1987. Clin Chem. eds. Washington. Hicks JM. Chapelsky LJ. Daxenbichler G.B. Pediatric reference intervals for plasma renin. et al. T3. Pediatric Reference Ranges. N-Telopeptide Cross-links (NTX) Mora S. serum insulin-like growth factor I. 1995:508. 1986. et al. 1995:380. Clin Biochem. J Clin Endocinol Metab. et al. Washington.B. 1995:538. 2nd ed. Albalos. adults and elderly subjects by HPLC with electrochemical detection.75(6):1491-1496. Munson S. Giwercman A. ed. Bailey JM. Feinstein C. children. 1994. Insulin-like Growth Factor II (IGF-II) Diagnostic Systems Laboratory Technical Communication. Clin Biochem.

Clin Chem. Direct Soldin SJ. MacFarlane G. 1993.B. Pediatric reference ranges for 25-hydroxy vitamin D using the DiaSorin Kit. 1981. Reference (Normal) Values. Clin Chem. LH. Beaty. T-Uptake. Morales A. TSH. Pediatric reference ranges on the Abbott Imx for FSH. 38:960. Albalos. Hicks JM. 1992. Pediatric reference ranges on the Abbott Imx for FSH. Washington. IgE and ferritin. Buffone GJ. Washington. DC: AACC Press. Thyroid-stimulating Hormone (TSH) Soldin SJ. 1992. free T4. Beaty et al. 1995:596. 1998. TSH. Washington. Philadelphia: W. Prolactin. LH. Cook J. Hicks JM. Thyroxine-binding Globulin (TBG) Hicks JM. free T4. Morales A. Clin Biochem. ed. eds. LH. 3rd ed. Thyroxine (T4) Soldin SJ. Philadelphia: W. Albalos. Vanillylmandelic Acid (VMA) Soldin SJ. IgE and ferritin. 25-Hydroxy Soldin SJ. Clinical Guide to Laboratory Tests. 1989:249. Cheng MH. Clin Biochem. Albalos. et al. et al. T4. prolactin. Pediatric reference ranges on the Abbott Imx for FSH. Pediatric reference ranges for thyroxine and triiodothyronine uptake. T4. free T3. Clin Chem. 1995. Pediatric reference ranges for thyroid binding globulin. DC: AACC Press. IgE and ferritin.B. Vitamin D. free T3. T3. 39:1172. 28:603-606. Morales A. Godwin ID. 1995:578. Pediatric Clinical Chemistry. et al. Saunders Company. Triiodothyronine (T3). TSH. Pediatric Reference Ranges. Free. T4. Cook J. Triiodothyronine (T3) Soldin SJ. 3rd ed. et al. Clin Chem. 44:A14. T-Uptake. Free Soldin SJ. 27:502-503. et al. 1995. Clinical Guide to Laboratory Tests. IgE and ferritin. Free by Ultrafiltration Tietz NW. 28:603-606. LH. free T4. et al. Triiodothyronine Uptake (T3U) Soldin SJ. Morales A. Pediatric reference ranges on the Abbott Imx for FSH. Murthy JN. Thyroglobulin Meites S. T4. Clin Biochem. prolactin. 28:603-606. Thyroxine (T4). Liquid chromatographic analysis for urinary 4-hydrozy-3-methoxy-mandelic acid and 4-hydroxy-3-mehoozyphenyl acetic acid and ist use in investigation of neural crest tumors. Clin Chem. T3. Soldin SJ. free T3. T-Uptake. Thyroxine (T4). Saunders Company. Lauber B. 1995:141. free T3. TSH. T3. Reverse Soldin SJ. T3. DC: AACC Press. 1995:132. Beatey J. free T4. T-Uptake. 1995. eds. 14 . Albalos. Triiodothyronine (T3). Pediatric reference ranges for thyroxine and triiodothyronine uptake. et al. 1995. Hill JG. Clin Biochem.Testosterone. ed. Free by Ultrafiltration Tietz NW. 28:603-606. 3rd ed. 38:960. eds. Pediatric Reference Ranges. Prolactin.