ID Visit (week) Mobility Self care Usual activity

1 4 1 2 1
2 8 1 1 3
3 12 1 1 1
4 16 3 1 2
5 20 3 2 1
6 24 3 2 1
7 4 3 2 2
8 8 1 2 1
9 12 3 2 2
10 16 2 2 1
11 20 2 2 3
12 24 3 1 3
13 4 2 2 1
14 8 1 2 3
15 12 2 1 3
16 16 3 2 1
17 20 3 2 2
18 24 1 1 1
19 4 1 1 3
20 8 3 1 3
21 12 2 2 3
22 16 3 2 3
23 20 3 2 3
24 24 1 1 2
25 4 2 2 3
26 8 3 2 1
27 12 3 1 2
28 16 1 2 1
29 20 1 1 3
30 24 3 1 3
31 4 2 1 2
32 8 1 2 1
33 12 2 1 1
34 16 2 2 2
35 20 2 2 1
36 24 2 1 2
37 4 1 2 3
38 8 1 1 1
39 12 1 1 2
40 16 2 2 2
41 20 3 2 1
42 24 2 2 3
43 4 3 2 3
44 8 2 1 2
45 12 2 1 3
46 16 1 1 2
47 20 3 1 3

48 24 1 1 1
49 4 3 2 2
50 8 3 1 2
51 12 1 1 2
52 16 3 1 3
53 20 3 2 3
54 24 2 1 2
55 4 3 1 2
56 8 2 2 1
57 12 2 2 1
58 16 2 1 1
59 20 2 2 2
60 24 1 2 2
61 4 1 2 3
62 8 3 1 3
63 12 2 1 2
64 16 3 1 3
65 20 3 1 1
66 24 3 2 2
67 4 1 1 3
68 8 1 2 3
69 12 1 1 2
70 16 1 2 1
71 20 1 2 2
72 24 3 1 3
73 4 3 1 2
74 8 1 2 2
75 12 3 2 1
76 16 2 2 1
77 20 3 2 2
78 24 3 2 2
79 4 3 1 2
80 8 1 2 1
81 12 1 2 3
82 16 2 1 3
83 20 1 2 3
84 24 3 2 1
85 4 2 1 1
86 8 1 1 3
87 12 1 1 1
88 16 3 1 2
89 20 1 1 3
90 24 2 1 3
91 4 1 2 1
92 8 2 2 3
93 12 1 1 1
94 16 1 1 3
95 20 1 1 1

96 24 3 1 2
97 4 3 1 1
98 8 3 1 2
99 12 3 1 2
100 16 3 2 2
101 20 3 1 1
102 24 3 2 2
103 4 2 2 2
104 8 1 2 2
105 12 2 1 3
106 16 1 2 1
107 20 3 1 2
108 24 3 2 1
109 4 3 2 3
110 8 2 2 1
111 12 1 1 2
112 16 1 2 2
113 20 2 1 2
114 24 3 2 3
115 4 2 2 3
116 8 2 2 1
117 12 1 2 1
118 16 2 2 1
119 20 2 2 1
120 24 3 2 1
121 4 2 2 3
122 8 2 2 2
123 12 1 1 1
124 16 2 2 3
125 20 3 2 2
126 24 1 2 1
127 4 1 2 3
128 8 2 2 3
129 12 3 2 1
130 16 3 1 2
131 20 3 1 2
132 24 3 2 1
133 4 2 2 1
134 8 3 1 2
135 12 3 2 2
136 16 2 2 2
137 20 3 1 3
138 24 3 1 1
139 4 2 2 2
140 8 2 2 2
141 12 3 1 1
142 16 2 1 1
143 20 1 2 1

144 24 2 2 3 145 4 2 1 2 146 8 3 2 2 147 12 3 2 1 148 16 2 1 3 149 20 2 1 3 150 24 1 2 1 151 4 3 1 3 152 8 1 1 3 153 12 1 2 2 154 16 1 2 2 155 20 1 2 2 156 24 2 2 2 157 4 2 2 1 158 8 2 2 1 159 12 2 2 2 160 16 3 1 2 161 20 3 2 2 162 24 2 1 2 163 4 1 1 2 164 8 3 2 3 165 12 1 1 3 166 16 1 2 1 167 20 1 2 3 168 24 1 2 2 169 4 2 1 3 170 8 2 2 1 171 12 3 1 1 172 16 3 2 1 173 20 1 1 2 174 24 2 2 3 175 4 2 2 1 176 8 3 1 3 177 12 2 1 3 178 16 3 2 2 179 20 1 1 2 180 24 1 2 3 181 4 1 1 2 182 8 2 1 1 183 12 2 1 3 184 16 1 2 1 185 20 1 1 2 186 24 2 1 2 187 4 1 1 3 188 8 2 2 1 189 12 1 1 1 190 16 2 1 3 191 20 1 2 3 .

192 24 3 2 1 193 4 1 2 1 194 8 2 2 3 195 12 1 2 2 196 16 3 1 3 197 20 3 2 3 198 24 1 2 1 199 4 3 2 1 200 8 2 1 2 201 12 1 2 1 202 16 2 2 1 203 20 2 1 1 204 24 1 1 2 205 4 2 2 3 206 8 3 2 3 207 12 3 1 3 208 16 3 2 2 209 20 1 2 2 210 24 3 2 1 211 4 2 2 2 212 8 2 1 1 213 12 1 2 2 214 16 2 1 2 215 20 3 2 1 216 24 2 2 1 217 4 2 2 1 218 8 3 2 3 219 12 1 2 1 220 16 1 2 3 221 20 2 1 2 222 24 1 2 2 223 4 1 2 1 224 8 3 2 3 225 12 3 2 2 226 16 3 2 3 227 20 3 1 2 228 24 1 1 2 229 4 1 2 1 230 8 3 2 1 231 12 2 2 2 232 16 3 1 3 233 20 1 1 3 234 24 3 1 1 235 4 1 2 3 236 8 1 1 2 237 12 1 1 3 238 16 1 2 3 239 20 1 2 3 .

240 24 1 2 3 241 4 2 2 3 242 8 1 1 1 243 12 2 1 1 244 16 2 1 2 245 20 3 1 2 246 24 1 2 2 247 4 3 2 1 248 8 3 2 1 249 12 1 2 3 250 16 3 2 1 251 20 2 2 3 252 24 1 1 1 253 4 3 1 3 254 8 3 1 2 255 12 2 1 2 256 16 2 2 2 257 20 3 2 1 258 24 1 2 2 259 4 1 2 2 260 8 1 1 3 261 12 3 2 2 262 16 2 1 1 263 20 1 1 2 264 24 3 1 2 265 4 1 2 3 266 8 2 2 3 267 12 2 2 3 268 16 2 2 2 269 20 1 2 1 270 24 1 2 2 271 4 1 1 1 272 8 1 2 3 273 12 2 2 2 274 16 1 2 3 275 20 3 1 3 276 24 3 2 2 277 4 2 2 1 278 8 1 2 2 279 12 2 1 1 280 16 3 2 3 281 20 2 2 3 282 24 3 2 3 283 4 1 1 2 284 8 3 2 2 285 12 1 1 3 286 16 1 1 3 287 20 2 2 2 .

288 24 3 2 1 289 4 2 1 3 290 8 2 2 2 291 12 1 2 2 292 16 3 1 1 293 20 1 1 2 294 24 3 1 2 295 4 1 2 3 296 8 1 1 3 297 12 2 1 2 298 16 2 2 1 299 20 2 1 2 300 24 3 1 1 301 4 1 2 2 302 8 1 2 1 303 12 1 1 1 304 16 3 2 3 305 20 1 1 2 306 24 3 2 3 307 4 2 1 3 308 8 1 1 2 309 12 3 2 2 310 16 1 2 3 311 20 2 2 3 312 24 3 2 1 313 4 2 1 1 314 8 3 2 3 315 12 3 2 2 316 16 3 1 3 317 20 1 2 3 318 24 2 1 3 319 4 3 1 1 320 8 2 2 3 321 12 1 2 3 322 16 3 1 1 323 20 3 2 1 324 24 1 1 2 325 4 3 2 3 326 8 3 1 3 327 12 3 2 3 328 16 3 2 2 329 20 3 2 3 330 24 3 1 3 331 4 2 2 1 332 8 3 2 3 333 12 2 1 2 334 16 1 1 2 335 20 3 2 2 .

336 24 1 1 2 337 4 3 1 2 338 8 3 1 1 339 12 1 1 3 340 16 3 1 2 341 20 2 1 2 342 24 2 1 3 343 4 3 1 2 344 8 3 1 3 345 12 1 2 1 346 16 2 2 2 347 20 1 2 2 348 24 2 2 3 349 4 2 1 1 350 8 1 2 1 351 12 1 1 2 352 16 3 1 2 353 20 2 2 3 354 24 3 2 1 355 4 3 2 2 356 8 3 2 3 357 12 3 2 1 358 16 3 2 2 359 20 2 2 1 360 24 3 1 1 361 4 1 1 3 362 8 3 2 1 363 12 1 1 3 364 16 1 1 3 365 20 2 1 3 366 24 2 1 1 367 4 2 1 1 368 8 3 1 3 369 12 2 1 3 370 16 2 1 2 371 20 3 1 3 372 24 2 2 3 373 4 1 1 2 374 8 2 1 2 375 12 3 1 2 376 16 2 1 1 377 20 1 1 1 378 24 1 2 1 379 4 2 2 2 380 8 2 1 2 381 12 1 1 3 382 16 2 2 1 383 20 1 1 1 .

384 24 3 2 1 385 4 1 1 2 386 8 2 2 3 387 12 2 1 3 388 16 2 2 2 389 20 3 2 3 390 24 2 1 2 391 4 2 1 1 392 8 3 1 3 393 12 3 2 3 394 16 1 2 1 395 20 1 2 1 396 24 2 1 2 397 4 2 1 1 398 8 2 1 1 399 12 1 1 3 400 16 1 2 1 401 20 2 1 3 402 24 2 2 2 403 4 1 1 1 404 8 3 1 3 405 12 3 1 2 406 16 2 1 1 407 20 3 2 2 408 24 1 1 2 409 4 1 2 3 410 8 2 1 2 411 12 3 2 1 412 16 2 2 1 413 20 2 1 1 414 24 2 2 1 415 4 2 1 2 416 8 2 2 3 417 12 1 1 3 418 16 1 2 3 419 20 1 1 1 420 24 1 1 1 421 4 1 2 1 422 8 1 1 3 423 12 3 2 1 424 16 2 2 1 425 20 3 1 2 426 24 2 2 2 427 4 3 1 2 428 8 2 1 2 429 12 1 1 1 430 16 2 2 3 431 20 1 2 1 .

432 24 1 2 2 433 4 1 1 1 434 8 1 2 2 435 12 1 1 1 436 16 3 2 2 437 20 1 2 2 438 24 2 1 2 439 4 1 1 1 440 8 1 2 3 441 12 2 1 2 442 16 1 1 1 443 20 1 1 1 444 24 3 2 1 445 4 1 2 2 446 8 1 1 1 447 12 1 2 2 448 16 1 2 1 449 20 1 2 1 450 24 3 2 3 451 4 2 1 3 452 8 1 1 2 453 12 1 1 2 454 16 3 1 1 455 20 1 1 3 456 24 3 2 1 457 4 2 1 3 458 8 1 1 2 459 12 1 2 3 460 16 3 2 2 461 20 1 1 2 462 24 3 1 2 463 4 3 2 1 464 8 2 1 1 465 12 3 1 1 466 16 2 1 1 467 20 3 2 3 468 24 3 1 3 469 4 1 2 1 470 8 3 2 2 471 12 2 2 2 472 16 3 1 1 473 20 3 2 1 474 24 1 1 1 475 4 2 2 3 476 8 2 1 3 477 12 1 1 1 478 16 1 1 2 479 20 2 2 1 .

480 24 3 2 3 481 4 3 2 1 482 8 1 2 1 483 12 1 1 3 484 16 1 1 3 485 20 3 1 2 486 24 3 2 3 487 4 3 2 1 488 8 3 1 1 489 12 2 2 1 490 16 3 2 1 491 20 2 1 3 492 24 2 2 1 493 4 3 2 2 494 8 1 2 3 495 12 3 2 3 496 16 3 2 1 497 20 1 1 2 498 24 1 1 1 499 4 1 1 2 500 8 3 1 2 501 12 2 1 1 502 16 3 2 1 503 20 3 1 1 504 24 1 2 3 505 4 1 1 1 506 8 1 2 1 507 12 1 2 1 508 16 1 1 2 509 20 2 1 2 510 24 3 1 2 511 4 1 1 1 512 8 2 2 2 513 12 3 2 2 514 16 3 2 1 515 20 3 1 3 516 24 3 2 1 517 4 3 1 2 518 8 2 2 1 519 12 2 1 2 520 16 1 2 2 521 20 2 1 3 522 24 3 1 3 523 4 3 2 3 524 8 1 1 3 525 12 3 1 3 526 16 1 2 3 527 20 3 2 3 .

528 24 1 1 3 529 4 3 1 2 530 8 3 2 2 531 12 2 1 1 532 16 1 1 3 533 20 3 1 2 534 24 2 2 2 535 4 3 2 1 536 8 1 1 3 537 12 2 2 3 538 16 1 2 3 539 20 3 2 3 540 24 1 1 2 541 4 2 1 3 542 8 2 2 3 543 12 1 2 3 544 16 3 2 1 545 20 2 2 3 546 24 2 2 2 547 4 3 1 3 548 8 3 1 2 549 12 2 2 1 550 16 1 1 1 551 20 3 1 2 552 24 3 1 1 553 4 3 2 2 554 8 1 1 2 555 12 2 1 2 556 16 1 2 1 557 20 3 2 1 558 24 1 2 2 559 4 1 2 3 560 8 2 1 2 561 12 1 1 1 562 16 2 2 3 563 20 3 1 3 564 24 2 2 1 565 4 1 1 2 566 8 3 1 1 567 12 2 2 1 568 16 2 1 3 569 20 1 2 2 570 24 3 2 3 571 4 3 2 2 572 8 3 2 1 573 12 1 1 3 574 16 3 2 1 575 20 1 1 2 .

576 24 3 1 2 577 4 3 2 2 578 8 2 1 2 579 12 2 2 2 580 16 3 1 3 581 20 1 2 1 582 24 1 1 2 583 4 1 1 3 584 8 1 1 2 585 12 3 1 2 586 16 2 1 3 587 20 3 2 1 588 24 1 1 3 589 4 3 2 2 590 8 2 1 3 591 12 3 1 1 592 16 1 1 3 593 20 3 1 2 594 24 3 2 3 595 4 2 1 3 596 8 1 2 1 597 12 2 1 1 598 16 3 1 1 599 20 1 1 1 600 24 1 1 3 601 4 3 1 3 602 8 1 2 3 603 12 1 1 2 604 16 2 1 1 605 20 2 2 3 606 24 2 1 2 607 4 1 2 3 608 8 2 2 3 609 12 2 1 2 610 16 3 2 1 611 20 3 1 2 612 24 1 1 1 613 4 2 1 3 614 8 3 1 2 615 12 3 2 3 616 16 3 1 2 617 20 2 1 1 618 24 1 1 2 619 4 2 1 3 620 8 2 2 1 621 12 3 2 3 622 16 2 2 1 623 20 2 2 1 .

624 24 1 1 2 625 4 2 2 2 626 8 1 1 3 627 12 1 1 1 628 16 3 1 2 629 20 2 1 2 630 24 2 2 3 631 4 3 1 1 632 8 1 2 3 633 12 2 1 3 634 16 3 2 1 635 20 1 2 2 636 24 1 1 1 637 4 2 1 3 638 8 3 1 2 639 12 1 1 3 640 16 1 2 1 641 20 2 1 1 642 24 3 1 1 643 4 3 2 1 644 8 2 1 2 645 12 2 2 1 646 16 3 1 2 647 20 1 2 2 648 24 3 1 3 649 4 3 1 1 650 8 1 1 2 651 12 3 2 1 652 16 1 1 1 653 20 1 1 3 654 24 3 2 1 655 4 2 2 2 656 8 2 2 1 657 12 2 2 3 658 16 1 1 2 659 20 2 2 3 660 24 1 1 3 661 4 1 1 2 662 8 3 2 1 663 12 1 2 3 664 16 2 1 1 665 20 3 2 1 666 24 2 1 1 667 4 2 1 1 668 8 2 2 2 669 12 1 2 3 670 16 1 2 2 671 20 1 1 2 .

672 24 2 1 3 673 4 3 1 3 674 8 2 1 1 675 12 2 2 2 676 16 1 2 1 677 20 1 2 1 678 24 3 2 2 679 4 1 1 1 680 8 3 1 2 681 12 1 1 1 682 16 1 1 3 683 20 1 2 2 684 24 1 1 1 685 4 2 1 3 686 8 2 2 3 687 12 1 1 3 688 16 1 2 1 689 20 2 2 1 690 24 2 1 2 691 4 1 2 3 692 8 3 2 2 693 12 3 2 1 694 16 2 2 2 695 20 3 2 3 696 24 3 1 1 697 4 3 2 1 698 8 2 1 1 699 12 2 2 3 700 16 2 2 2 701 20 2 1 2 702 24 2 2 1 703 4 3 1 3 704 8 3 1 3 705 12 2 1 3 706 16 3 1 1 707 20 2 2 1 708 24 2 1 2 709 4 3 1 1 710 8 1 2 2 711 12 2 1 1 712 16 2 1 3 713 20 3 2 2 714 24 3 1 3 715 4 3 1 2 716 8 1 1 3 717 12 1 2 1 718 16 3 2 3 719 20 3 2 2 .

720 24 1 2 3 721 4 3 1 2 722 8 3 2 1 723 12 1 2 3 724 16 3 2 3 725 20 1 2 3 726 24 3 1 1 727 4 3 2 2 728 8 2 2 3 729 12 2 2 3 730 16 1 2 2 731 20 2 1 3 732 24 1 2 3 733 4 2 1 3 734 8 1 2 3 735 12 1 1 3 736 16 1 2 2 737 20 3 2 1 738 24 1 2 3 739 4 1 1 3 740 8 3 1 2 741 12 3 1 2 742 16 2 2 3 743 20 2 1 1 744 24 1 1 1 745 4 3 2 2 746 8 3 2 2 747 12 2 1 1 748 16 3 2 3 749 20 2 2 2 750 24 1 2 1 751 4 3 1 2 752 8 2 2 3 753 12 2 2 3 754 16 2 1 3 755 20 2 1 1 756 24 3 2 3 757 4 1 2 1 758 8 3 2 2 759 12 2 2 3 760 16 3 1 2 761 20 2 1 2 762 24 1 1 1 763 4 2 1 1 764 8 1 1 2 765 12 1 2 1 766 16 1 1 3 767 20 2 1 1 .

768 24 3 1 2 769 4 3 2 2 770 8 3 1 1 771 12 1 1 1 772 16 1 1 1 773 20 2 1 1 774 24 1 2 1 775 4 3 1 1 776 8 1 2 3 777 12 1 2 2 778 16 2 2 2 779 20 1 1 1 780 24 3 1 2 781 4 3 2 2 782 8 3 2 1 783 12 3 1 2 784 16 3 2 3 785 20 2 1 1 786 24 3 2 2 787 4 1 1 3 788 8 1 1 1 789 12 2 2 1 790 16 3 1 3 791 20 1 1 2 792 24 3 2 1 793 4 3 1 2 794 8 1 1 1 795 12 3 2 1 796 16 3 1 1 797 20 3 1 1 798 24 3 2 1 799 4 3 1 2 800 8 2 2 1 801 12 2 2 1 802 16 1 1 1 803 20 3 2 3 804 24 2 2 3 805 4 3 1 1 806 8 3 1 1 807 12 3 2 3 808 16 1 1 2 809 20 2 2 1 810 24 3 1 3 811 4 1 2 2 812 8 2 1 3 813 12 3 1 2 814 16 3 2 1 815 20 1 2 3 .

816 24 3 1 3 817 4 2 1 1 818 8 1 1 3 819 12 3 1 2 820 16 3 2 3 821 20 3 1 1 822 24 3 1 3 823 4 3 2 2 824 8 2 1 3 825 12 1 2 1 826 16 1 1 1 827 20 1 1 2 828 24 3 1 2 829 4 2 2 2 .

104 1 1 -0.104 1 1 -0.069 -0.314 -0.314 0 3 2 -0.104 3 2 -0.104 1 2 -0.314 -0.314 0 .069 0 2 1 0 -0.314 -0.Pain Anxiety Mobility Utility Self Care Utility 3 2 0 -0.314 -0.104 2 1 -0.104 3 1 0 -0.104 1 1 0 0 1 2 0 0 3 2 -0.104 3 1 -0.104 3 2 -0.314 -0.104 1 2 -0.314 0 1 1 -0.069 -0.069 -0.069 0 3 2 -0.314 0 2 1 -0.069 0 2 2 -0.104 2 1 -0.104 1 2 0 0 1 2 -0.314 -0.104 1 1 -0.104 3 1 0 -0.104 1 1 -0.069 0 1 1 0 -0.314 -0.069 0 1 1 0 0 1 2 -0.069 0 2 2 -0.314 0 1 1 -0.104 2 1 0 0 3 2 0 0 2 2 -0.069 -0.104 2 1 -0.069 -0.104 3 1 -0.104 1 2 -0.104 2 1 -0.314 -0.104 3 2 -0.104 1 1 -0.104 3 1 0 0 1 1 -0.314 -0.314 0 3 2 0 -0.314 -0.104 3 2 -0.069 -0.069 -0.314 -0.069 -0.104 1 1 0 0 2 2 0 0 3 2 -0.104 3 2 -0.069 -0.

314 0 3 2 -0.2 2 0 0 1 2 -0.104 3 1 0 -0.069 0 2 2 0 -0.314 -0.314 0 2 1 -0.104 1 2 -0.314 -0.314 -0.069 0 1 2 -0.314 0 1 2 0 0 2 1 -0.069 -0.104 1 1 0 -0.104 1 2 -0.314 0 1 2 -0.314 0 3 1 -0.104 2 2 -0.104 1 2 -0.069 0 1 2 -0.104 1 1 0 -0.104 1 2 -0.069 -0.069 -0.314 -0.314 0 1 2 0 -0.314 0 3 2 -0.314 -0.104 2 2 -0.069 -0.314 0 1 2 -0.104 2 1 0 0 3 2 0 -0.104 3 1 -0.314 -0.104 1 1 -0.104 2 1 -0.104 2 1 -0.104 2 1 -0.104 2 2 -0.104 2 1 0 0 3 1 0 -0.069 -0.069 0 1 1 0 0 1 2 0 0 1 2 -0.314 0 3 1 0 -0.104 1 2 -0.314 -0.069 0 3 2 -0.104 2 2 -0.104 1 1 0 -0.104 3 2 -0.104 3 1 0 0 2 2 0 0 3 1 0 0 .314 0 3 1 0 0 3 2 -0.069 0 2 1 0 -0.

314 0 1 2 -0.069 -0.069 -0.104 3 1 -0.314 -0.104 3 2 -0.104 3 2 -0.314 -0.104 2 1 -0.314 -0.314 -0.314 0 2 1 -0.104 3 2 -0.104 3 1 -0.104 .069 0 1 1 0 -0.314 0 2 1 -0.314 0 3 2 -0.069 -0.104 2 1 -0.104 2 1 -0.314 -0.069 -0.104 1 2 -0.104 1 2 -0.069 0 1 1 -0.104 1 2 -0.104 2 1 -0.314 -0.314 0 2 1 -0.314 0 3 1 -0.314 -0.069 -0.314 -0.069 -0.104 3 1 -0.104 1 2 0 0 1 2 -0.104 2 1 -0.104 1 2 -0.069 -0.104 3 2 0 -0.069 -0.314 0 3 2 -0.3 2 -0.069 0 3 2 0 -0.104 1 2 -0.104 2 2 -0.069 -0.069 -0.104 3 2 -0.104 1 1 -0.314 0 3 1 -0.069 -0.314 -0.314 0 2 1 -0.104 1 1 -0.314 0 3 1 -0.104 1 2 0 -0.314 0 1 2 -0.104 1 1 0 -0.104 1 1 -0.104 3 1 -0.104 2 2 -0.314 -0.104 3 2 0 -0.104 3 1 -0.104 1 2 0 0 2 2 0 -0.069 -0.314 0 1 2 -0.069 -0.069 -0.

104 3 1 -0.069 0 3 1 -0.069 0 2 1 -0.314 -0.069 -0.069 -0.104 2 1 -0.314 0 2 2 -0.314 0 1 2 -0.069 0 2 1 0 -0.069 0 2 2 -0.104 3 2 -0.069 -0.069 0 1 2 -0.104 3 1 -0.069 0 2 2 0 -0.104 .069 -0.314 0 3 1 0 0 2 2 0 -0.104 1 1 0 0 2 1 -0.104 2 2 0 0 1 2 0 -0.104 1 1 0 -0.069 -0.104 1 2 -0.2 2 -0.104 2 2 -0.104 1 1 0 0 2 2 -0.314 -0.069 -0.104 1 1 -0.104 2 2 0 -0.069 0 2 1 -0.314 -0.069 -0.314 -0.314 -0.069 0 1 1 0 0 2 2 -0.314 0 3 1 -0.104 1 1 -0.104 3 2 -0.314 -0.069 0 2 1 0 -0.104 3 2 0 0 3 2 0 -0.104 2 1 -0.104 3 1 -0.069 -0.104 1 2 -0.069 0 3 2 0 0 2 2 -0.069 -0.104 1 2 0 0 1 2 -0.104 2 1 0 0 2 2 -0.104 2 1 0 -0.104 3 1 -0.104 3 2 0 -0.104 2 1 -0.

104 3 2 -0.104 3 1 -0.069 0 2 2 0 0 3 1 -0.104 1 1 -0.104 1 1 -0.069 -0.104 3 1 0 -0.1 1 -0.069 -0.104 3 2 -0.104 .104 2 2 0 -0.104 3 2 -0.069 -0.104 3 2 -0.069 0 2 2 0 -0.104 1 1 -0.104 2 2 -0.104 2 1 -0.104 1 2 -0.314 -0.104 2 2 0 -0.104 1 2 0 0 3 1 0 0 3 1 0 -0.104 3 1 -0.314 -0.104 2 1 0 -0.104 1 1 -0.104 3 2 -0.314 -0.104 3 2 -0.314 -0.104 1 2 -0.104 1 1 -0.069 -0.314 -0.104 2 2 0 -0.314 -0.069 0 3 1 0 -0.069 -0.104 3 1 -0.314 -0.104 1 1 0 -0.069 -0.104 3 1 -0.314 -0.104 1 2 0 -0.314 0 3 2 0 0 3 1 0 -0.069 0 3 1 0 -0.314 0 2 1 -0.104 2 1 -0.314 0 2 2 0 -0.104 1 2 -0.314 0 3 2 0 0 1 1 -0.314 -0.069 -0.104 1 2 0 -0.314 0 2 1 -0.104 2 2 -0.314 -0.314 -0.104 1 1 -0.314 -0.069 0 1 1 -0.

314 0 1 1 -0.314 -0.069 0 2 2 -0.069 0 1 2 -0.104 2 1 -0.104 2 2 -0.314 -0.314 0 3 2 0 -0.069 -0.104 1 1 0 0 3 2 0 -0.104 2 2 0 -0.104 2 1 0 -0.314 -0.104 3 2 0 0 2 2 -0.069 -0.069 0 2 1 -0.314 -0.104 3 2 -0.104 3 2 0 -0.104 1 2 0 -0.104 3 2 -0.104 3 1 -0.104 2 2 -0.314 -0.104 3 2 0 0 1 1 -0.104 1 1 0 -0.104 2 1 -0.069 -0.104 2 2 -0.104 1 1 0 -0.069 -0.069 -0.069 -0.3 1 0 -0.104 3 1 0 0 1 2 0 0 3 1 -0.104 2 1 -0.314 -0.104 2 1 0 0 2 2 -0.069 -0.104 .104 3 1 -0.104 1 2 -0.314 -0.104 1 2 -0.069 0 1 1 0 0 3 2 -0.104 3 1 0 -0.069 -0.104 1 2 -0.104 2 1 -0.314 0 2 1 -0.314 0 1 1 -0.314 0 1 2 0 -0.104 2 1 0 0 1 1 -0.069 -0.104 2 1 -0.314 -0.314 -0.104 2 2 -0.069 -0.069 0 2 1 -0.

069 0 2 1 -0.104 3 1 -0.314 -0.104 1 2 -0.314 0 1 1 0 -0.104 2 2 -0.2 2 -0.069 -0.104 1 1 -0.069 0 3 2 -0.314 -0.104 2 1 0 -0.104 1 2 0 -0.104 3 2 -0.104 1 2 0 0 3 1 -0.104 3 2 -0.314 -0.314 -0.069 0 2 2 -0.104 2 2 0 0 1 1 -0.069 -0.104 1 2 -0.069 0 1 2 0 0 1 1 -0.069 -0.314 0 3 2 -0.069 -0.104 3 1 0 -0.104 3 1 -0.314 -0.314 -0.104 3 1 -0.314 -0.104 1 1 -0.069 0 1 1 0 0 2 2 -0.104 3 1 0 0 3 2 -0.104 1 2 -0.314 -0.069 0 1 2 -0.104 2 2 0 0 1 2 -0.104 .314 -0.314 0 1 2 -0.069 -0.069 0 1 2 -0.314 0 2 1 0 0 1 1 -0.314 -0.104 2 1 -0.104 1 1 -0.104 1 1 -0.314 0 3 1 0 -0.314 0 3 1 -0.314 -0.314 0 2 2 -0.314 0 3 2 0 -0.314 -0.104 2 1 -0.314 -0.104 2 1 0 -0.104 3 2 -0.314 -0.104 2 2 -0.

104 1 1 0 0 3 2 -0.104 3 2 0 0 .314 -0.104 2 1 -0.314 0 1 2 -0.104 2 2 0 0 3 2 -0.314 0 3 2 0 -0.069 0 1 1 0 0 1 1 -0.104 1 2 -0.069 0 1 1 0 0 1 1 0 -0.314 -0.314 0 1 1 -0.104 3 1 -0.104 2 2 -0.069 0 1 1 -0.069 -0.069 -0.314 -0.069 -0.069 0 3 1 -0.069 0 2 2 -0.104 1 1 -0.069 0 2 1 -0.314 0 1 1 -0.069 0 3 2 -0.069 0 3 1 -0.104 3 1 -0.314 -0.314 -0.314 0 2 1 -0.3 2 0 0 3 1 -0.104 1 2 0 -0.069 0 1 1 -0.069 0 2 2 0 -0.104 1 1 -0.314 -0.104 1 2 -0.104 1 1 -0.104 2 2 -0.069 -0.314 0 3 1 0 0 2 2 -0.069 -0.314 0 1 2 0 0 1 1 -0.104 3 2 -0.069 -0.314 0 2 2 -0.069 0 2 1 -0.104 1 2 0 0 3 1 0 0 1 2 -0.314 0 3 2 -0.104 3 1 -0.069 -0.314 0 3 2 -0.

104 .104 1 1 -0.104 1 1 0 0 1 2 -0.069 0 2 2 -0.069 0 1 1 -0.069 -0.314 -0.314 0 3 1 -0.069 0 1 1 0 0 2 1 -0.104 3 1 -0.069 -0.314 0 1 1 -0.104 1 2 0 0 2 1 0 -0.069 -0.069 0 2 2 0 0 3 1 0 -0.069 0 2 2 -0.069 -0.104 3 1 0 -0.104 2 1 -0.069 0 2 2 -0.104 3 1 0 0 3 2 -0.069 -0.314 -0.314 0 2 2 -0.104 1 2 0 0 1 2 -0.069 -0.314 -0.069 0 3 2 -0.104 1 1 -0.314 0 2 1 -0.104 3 1 -0.3 1 -0.104 1 1 -0.104 2 1 -0.104 2 2 -0.314 0 3 1 -0.069 0 3 2 -0.104 2 1 0 -0.104 2 2 -0.069 -0.314 -0.069 0 1 1 -0.314 -0.069 -0.314 -0.069 -0.104 3 2 0 0 3 1 0 -0.069 0 3 2 -0.069 0 3 1 -0.069 0 3 2 -0.104 2 1 -0.104 2 2 -0.104 2 1 0 0 1 1 0 0 3 1 0 -0.104 2 2 0 -0.104 2 1 -0.

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269 0.269 0.074 -0.086 -0.177 -0.269 -0.269 0.121 -0.067 0 0.585 -0.159 -0.016 0 0.138 -0.675 0 0.623 -0.269 -0.073 0 0.269 -0.269 0.269 -0.229 -0.177 -0.269 0.073 0 0.293 0 0.269 -0.312 -0.815 -0.269 -0.154 -0.232 -0.269 -0.269 0.812 0 0.26 0 0.177 -0.157 -0.269 0.269 0.02 -0.269 0.675 0 0.269 0.055 0 0.848 -0.269 -0.516 -0.05 0 0.269 -0.269 0.744 0 0.269 0.121 -0.261 -0.269 0.269 -0.154 0 0.269 -0.269 0.269 0.815 -0.269 0.269 0.383 -0.053 -0.144 -0.177 -0.269 0.161 -0.005 -0.-0.269 0.269 0.779 -0.089 .269 -0.269 -0.639 -0.125 0 0.269 0.05 -0.587 -0.746 -0.

269 0.269 0.053 0 0.121 -0.585 -0.055 0 0.779 -0.587 -0.269 0.269 0.269 0.416 -0.159 0 0.269 0.675 -0.269 0.269 0.364 -0.269 0.269 0.312 0 0.269 0.62 -0.329 .17 0 0.056 -0.329 0 0.073 0 0.099 -0.269 0.416 -0.381 0 0.812 -0.883 0 0.585 -0.189 0 0.109 -0.675 -0.144 -0.269 0.269 0.76 0 0.689 -0.293 0 0.269 -0.089 -0.364 0 0.19 -0.269 0.086 -0.746 -0.692 0 0.269 -0.656 -0.099 0 0.02 0 0.269 -0.269 0.269 -0.621 -0.269 -0.154 0 0.552 0 1 -0.364 0 0.269 0.269 0.814 -0.269 -0.269 0.269 0.269 0.269 0.883 -0.-0.269 0.002 -0.048 -0.

319 -0.161 -0.195 0 0.119 -0.744 -0.269 -0.258 0 0.269 0.154 -0.269 0.383 0 0.269 0.269 0.269 0.269 -0.269 0.269 0.269 0.16 -0.073 0 0.552 -0.269 0.585 -0.124 0 0.269 -0.269 0.692 -0.232 -0.269 0.269 0.336 -0.814 -0.269 0.269 0.196 -0.067 -0.269 0.269 -0.232 0 0.779 -0.269 0.159 -0.269 0.099 -0.016 -0.242 -0.003 -0.269 0.675 -0.585 -0.16 0 0.269 0.269 0.016 -0.746 0 0.269 -0.157 -0.269 0.124 0 0.258 .066 -0.16 -0.269 0.269 0.269 0.215 -0.159 -0.015 0 0.269 0.269 0.269 0.258 0 0.269 -0.812 -0.056 -0.744 -0.269 -0.177 -0.689 -0.269 0.269 -0.232 0 0.319 -0.-0.17 -0.

269 -0.691 0 0.269 0.312 -0.269 0.452 -0.269 -0.516 0 0.587 -0.26 -0.269 0.269 0.269 -0.269 0.124 0 1 -0.585 0 0.485 -0.225 0 0.193 -0.269 0.639 -0.433 -0.269 0.269 0.269 0.269 0.005 0 0.242 -0.005 -0.038 -0.269 0.055 .883 -0.269 0.269 0.269 0.269 0.269 -0.196 -0.177 0 0.269 -0.17 -0.26 0 0.3 0 0.708 -0.727 -0.269 0.691 -0.269 -0.189 -0.157 -0.-0.623 0 0.002 -0.269 0.269 0.048 -0.452 -0.269 0.161 -0.656 0 0.708 -0.154 -0.269 -0.056 -0.053 -0.196 0 0.269 0.319 -0.269 0.269 0.269 0.157 -0.269 0.269 0.796 0 0.195 0 0.066 -0.692 -0.312 0 0.269 0.

269 0.293 -0.814 0 0.269 0.269 -0.038 -0.269 0.196 -0.269 0.416 -0.269 0.269 -0.016 0 0.269 0.552 -0.269 0.362 0 0.159 0 0.656 -0.725 -0.067 0 0.269 0.883 -0.269 -0.269 0.03 0 0.336 0 0.312 -0.269 0.269 0.269 0.269 0.213 0 0.269 0.269 0.269 0.269 0.779 0 0.319 -0.066 -0.144 -0.02 -0.138 -0.727 -0.005 -0.213 -0.269 0.228 -0.269 0.002 .269 0.074 -0.269 0.265 -0.269 0.066 -0.242 -0.088 -0.269 0.-0.381 -0.067 -0.812 -0.269 0.812 -0.269 0.002 -0.171 -0.161 0 0.3 -0.248 -0.269 -0.248 -0.269 -0.269 -0.038 -0.692 0 0.196 -0.269 -0.269 0.269 0.248 -0.269 -0.269 0.76 -0.269 0.

487 -0.269 -0.269 -0.689 -0.269 -0.269 0.215 -0.269 0.269 0.269 0.269 0.269 0.269 0.269 0.485 -0.-0.269 -0.269 0.269 0.088 -0.086 -0.779 0 1 0 0.269 0.746 -0.248 -0.269 0.3 -0.125 -0.17 -0.269 0.269 -0.269 0.074 0 0.269 0.815 -0.055 0 0.144 -0.195 0 0.269 0.196 0 0.269 0.157 -0.743 -0.17 -0.621 0 0.269 0.336 -0.269 0.691 -0.086 0 0.269 -0.269 0.189 -0.727 0 0.106 0 0.552 -0.485 -0.487 -0.016 0 0.269 -0.269 0.269 0.416 0 0.157 -0.336 -0.269 -0.232 -0.883 -0.232 -0.269 0.708 -0.109 -0.269 0.193 .048 -0.556 0 0.189 -0.269 0.727 -0.269 0.269 0.088 -0.089 -0.

656 -0.269 0.269 0.177 0 0.269 0.796 0 1 -0.-0.225 0 0.623 0 0.487 0 0.269 0.269 -0.312 -0.362 -0.269 0.814 -0.269 0.269 -0.261 -0.552 -0.329 0 0.269 0.177 -0.485 -0.124 -0.269 0.656 -0.17 -0.269 0.692 .269 0.138 0 0.516 -0.269 0.293 -0.157 -0.195 -0.159 -0.269 0.269 0.016 0 1 -0.269 0.124 -0.171 -0.269 0.269 -0.066 0 0.154 0 0.269 0.269 0.038 0 0.159 -0.015 0 0.269 0.812 -0.269 0.269 0.269 0.242 -0.269 -0.269 0.091 -0.269 0.16 -0.269 0.621 -0.516 -0.3 -0.269 0.26 0 0.16 -0.691 0 0.269 0.16 -0.159 0 1 -0.383 -0.269 0.269 0.269 0.

0 0.336 -0.269 0.796 -0.177 -0.269 0.383 -0.269 0.264 0 0.159 0 0.232 0 0.85 -0.269 -0.269 -0.101 0 0.269 0.269 0.692 0 0.269 0.812 -0.708 0 0.269 0.056 -0.02 .055 -0.585 -0.269 0.708 0 1 0 0.269 0.812 -0.225 -0.269 0.364 0 0.269 0.269 0.109 -0.269 0.264 -0.779 0 0.258 -0.269 0.269 0.269 0.269 0.269 0.485 -0.015 -0.228 -0.269 0.336 0 0.76 0 0.196 -0.124 -0.269 0.269 0.269 0.269 0.779 0 0.142 -0.242 0 0.232 -0.691 0 0.269 0.269 0.725 -0.744 -0.689 -0.269 0.416 -0.196 0 0.452 -0.796 -0.269 0.621 -0.196 -0.725 0 0.193 0 0.

269 0.038 -0.269 -0.154 0 0.516 -0.138 -0.171 -0.485 -0.269 -0.552 -0.796 0 0.109 -0.815 -0.883 -0.269 0.119 -0.269 0.086 0 1 0 0.269 0.269 0.269 -0.452 -0.3 0 0.269 0.269 -0.485 -0.336 -0.232 0 0.623 -0.144 -0.269 0.556 -0.269 0.779 -0.269 0.848 0 0.779 -0.269 0.269 0.269 0.066 0 0.269 0.269 0.109 -0.269 0.814 0 0.269 0.159 -0.269 -0.-0.416 -0.248 -0.005 -0.248 -0.416 0 0.138 .812 -0.177 -0.815 -0.269 -0.089 0 0.229 0 0.261 -0.269 -0.269 0.261 -0.269 0.269 -0.015 -0.269 0.269 0.109 -0.883 0 0.269 0.746 0 0.269 -0.269 0.269 0.269 0.05 0 0.038 -0.

708 -0.161 -0.121 -0.815 -0.005 -0.796 -0.225 0 0.073 -0.189 -0.269 0.623 0 0.269 -0.587 -0.195 -0.053 -0.269 -0.269 -0.329 -0.106 -0.269 0.269 0.-0.269 0.091 -0.269 0.215 -0.157 -0.26 -0.005 0 0.125 -0.62 0 0.269 0.088 0 0.269 0.269 0.144 0 0.269 0.725 -0.269 -0.269 0.067 0 0.269 -0.76 -0.485 -0.269 0.269 0.269 0.269 0.312 -0.269 0.883 .269 -0.269 0.269 -0.269 -0.269 0.269 0.101 -0.269 -0.269 0.154 -0.161 0 0.383 -0.269 0.099 -0.099 -0.177 -0.269 0.269 0.269 0.3 0 0.269 0.154 -0.269 0.269 0.213 -0.229 0 0.03 -0.552 -0.17 -0.269 0.269 0.248 -0.228 -0.002 -0.269 0.055 -0.

269 0.269 0.154 -0.364 -0.229 -0.106 -0.269 0.269 0.692 0 0.269 0.76 -0.048 -0.269 0.269 0.269 0.269 0.689 -0.229 -0.101 -0.269 -0.269 0.248 -0.269 0.416 -0.-0.232 -0.727 -0.17 -0.364 -0.692 0 0.675 .269 0.005 0 0.269 0.269 0.067 -0.269 -0.269 -0.19 0 0.814 0 0.312 0 0.691 -0.073 -0.269 -0.269 -0.269 0.02 -0.269 0.269 0.269 -0.269 -0.452 -0.124 0 0.269 -0.157 -0.269 0.264 -0.264 -0.121 -0.269 0.269 0.074 0 0.177 -0.269 0.269 0.05 -0.639 -0.812 0 0.269 0.556 0 0.269 0.656 -0.091 0 0.76 -0.269 0.101 0 0.015 -0.269 0.691 -0.269 0.229 -0.433 -0.556 -0.119 0 0.

812 -0.269 0.269 0.228 -0.225 0 0.312 0 0.269 -0.074 -0.556 0 0.269 0.269 -0.171 -0.269 0.124 -0.269 0.269 0.269 0.269 -0.269 0.623 -0.142 -0.091 -0.269 0.269 0.099 0 1 -0.656 0 0.516 0 0.269 0.269 0.485 0 0.-0.269 0.336 -0.264 -0.269 0.038 -0.416 -0.269 -0.3 -0.195 -0.362 -0.639 -0.452 -0.269 0.213 -0.159 -0.269 0.269 0.725 -0.232 -0.269 0.269 0.269 0.154 0 0.269 0.269 0.229 0 0.269 0.228 0 0.269 0.124 0 0.269 0.225 -0.587 -0.689 -0.381 0 0.269 0.258 -0.269 0.621 -0.743 -0.269 0.161 0 0.177 -0.124 -0.312 -0.03 -0.269 0.269 0.124 -0.269 0.708 -0.689 .

269 0.086 0 1 -0.124 0 0.293 -0.269 0.215 -0.067 -0.656 -0.62 -0.269 0.03 -0.744 -0.269 0.269 0.091 -0.814 -0.-0.3 -0.692 0 0.053 0 0.101 -0.269 0.269 -0.269 0.269 0.269 -0.119 -0.048 -0.485 0 0.269 0.675 0 0.269 -0.099 0 0.269 0.02 0 0.269 0.189 0 0.269 0.692 0 0.154 0 0.121 -0.261 0 1 -0.269 -0.248 -0.269 0.452 -0.002 -0.073 -0.269 0.269 -0.269 0.269 0.269 0.293 -0.744 -0.269 0.269 0.269 0.121 -0.269 0.269 -0.269 -0.055 -0.362 -0.225 -0.171 -0.269 0.587 -0.159 -0.383 -0.587 0 0.656 -0.269 0.073 .269 0.124 0 0.269 0.142 -0.269 -0.725 -0.269 0.

383 -0.124 -0.85 -0.639 -0.002 -0.26 -0.269 0.416 0 0.779 0 0.053 -0.099 0 0.089 -0.121 -0.269 0.269 0.381 -0.269 0.106 0 0.101 -0.269 0.269 0.106 -0.269 0.261 -0.269 0.62 0 1 0 0.269 -0.269 0.229 -0.269 0.248 -0.727 -0.269 0.002 0 0.193 -0.269 0.452 -0.383 -0.269 0.585 -0.269 0.689 0 0.381 -0.269 0.269 0.269 0.329 -0.269 0.189 -0.269 0.17 0 0.269 0.248 0 0.26 -0.269 0.779 .269 -0.269 -0.269 -0.269 0.269 0.086 -0.005 -0.269 0.269 0.815 -0.161 -0.269 -0.125 -0.-0.26 -0.269 -0.109 -0.269 0.452 -0.364 -0.229 -0.248 0 0.269 0.269 0.099 -0.269 -0.269 0.269 0.621 -0.

-0.269 0.106
-0.269 -0.19
-0.269 0.213
0 0.725
0 1
0 0.656
0 0.692
-0.269 0.265
-0.269 0.066
0 0.656
-0.269 -0.016
0 0.796
-0.269 0.177
-0.269 0.196
-0.269 -0.154
-0.269 0.177
-0.269 -0.248
0 0.85
-0.269 -0.19
-0.269 0.433
0 0.725
-0.269 0.091
-0.269 0.119
0 0.76
-0.269 -0.225
-0.269 -0.086
0 1
-0.269 -0.225
-0.269 0.336
-0.269 0.265
-0.269 0.109
-0.269 0.229
0 0.746
0 0.675
0 0.725
-0.269 0.067
-0.269 -0.074
-0.269 0.142
-0.269 0.265
-0.269 0.067
-0.269 0.228
-0.269 0.02
-0.269 -0.144
-0.269 0.124
-0.269 0.364
-0.269 -0.157
-0.269 -0.225
-0.269 0.381

-0.269 0.242
0 0.727
-0.269 0.17
-0.269 0.3
-0.269 0.067
-0.269 0.142
-0.269 0.171
-0.269 0.125
-0.269 0.293
-0.269 0.16
-0.269 0.193
0 0.76
-0.269 0.3
0 0.516

Week Average of Utility
4 0.296
8 0.286746
12 0.35092
16 0.294174
20 0.314601
24 0.254413

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214 Usual activities = 2 -0.123 Pain/discomfort = 3 -0.386 Anxiety/depression = 2 -0.236 D1 I2-square I3 I3-square .071 Anxiety/depression = 3 -0.081 At least one 3 (N3) -0.069 Mobility = 3 -0.104 Self care = 3 -0.314 Self care = 2 -0.269 Mobility = 2 -0.TTO value sets UK Full health (11111) 1 At least one 2 or 3 (constant) -0.036 Usual activities = 3 -0.094 Pain/discomfort = 2 -0.

2867463768 12 0.296 8 0.Visit (week) Average .Utility 4 0.294173913 20 0.3509202899 16 0.2994716526 .2544130435 Total Result 0.3146014493 24 0.