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Angiotensin-converting enzyme (ACE) 7. ACE inhibitor may cause cough in patients and
Antihypertensive Drugs inhibitors should inform the doctor immediately if this
They control the level of water and sodium ions
Hypertension refers to the prolonged and persistent
in blood to reduce blood pressure. Common 8. Patients who have asthma should consult doctor
elevation of blood pressure above the normal range.
examples are captopril, lisinopril and perindopril. before using beta-adrenoceptor antagonists.
If not treated properly, hyper tension can cause
severe complications such as stroke, coronary heart 4. Angiotensin II receptor antagonists Do not worry if you have any of these reactions. In
disease and kidney failure. most cases, such reactions would gradually subside
They have a similar mechanism to ACE
after the drugs have been taken for some time.
Patients with hypertension must take antihypertensive inhibitors. Common example is losartan.
Consult a doctor right away if the adverse reactions
drugs on a long-term basis. Although such drugs
5. Beta-adrenoceptor antagonists persist or aggravate.
cannot give a radical cure, they can prevent heart
failure, kidney failure and acute stroke induced They lower blood pressure by lowering the
by hyper tension and delay the development of heart rate. Common examples are atenolol and Advice on Medication
atherosclerosis by controlling the blood pressure. propanolol. The following should be borne in mind when taking
Generally speaking, antihypertensive drugs must be antihypertensive drugs:
All antihyper tensive drugs can only be sold on
taken for life.
doctors prescription in registered dispensaries, 1. Learn the name and dosage of the drugs you are
and should be taken regularly according to medical taking.
Classification of the Drugs instructions.
2. Take the drugs regularly as instructed by your
Antihypertensive drugs that are commonly used can
doctor in order to
be classified into the following categories: Side Effects of the Drugs have effective
1. Diuretics Side effects of antihyper tensive drugs vary with control of
They lower blood pressure by increasing individual drugs. Common side effects include the hypertension.
following temporary reactions: Keep on taking
urination. Common examples are
the drugs even if
hydrochlorothiazide and indapamide. 1. Headache, weakness or fatigue.
your conditions
2. Calcium channel blockers 2. Dizziness upon rising quickly improve.
They lower blood pressure by reducing from a sitting or lying position.
3. D o n o t s t o p
myocardial contractility. Common examples are 3. Numbness or sharp pain in medication without
nifedipine, felodipine and diltiazem. fingers or toes. your doctors instruction.
4. Cold hands and feet. Take your medicines at the same fixed time
every day as far as possible. If you miss a dose,
5. Dr y eyes, mouth and take it as soon as possible unless it is almost
throat. time for the next scheduled dose. In that case,
6. Nightmares or sleeping skip the missed dose and take the next dose as
difficulties directed. Do not take double doses.
4. The drugs should not be taken with alcoholic
drinks to avoid dizziness or fainting.
s. If you have to take other drugs as well such Storage of the Drugs
as cough syrup, drugs for common cold and
anti-cough medicines, you should consult your The drugs should be stored in a cool and dry place.
doctor first to avoid affecting the efficacy of the Generally, they do not need to be refrigerated unless
antihypertensive drugs. You may bring along your otherwise stated in the drug labels. Also, they should
medical history or labelled drug bags for your be stored properly to avoid accidents of mistaken
doctor's reference during follow-up consultation. consumption by children.

6. Do not put different drugs in the same bottle.

Each drug should be put into its original labelled
7. The stock of drugs should be sufficient for
several days' use. Do not wait till the last minute
to fill the prescription.

Life Adaptations
People with hypertension should take note of the
following in their daily lives:

I. Quit smoking.
2. Reduce salt intake. Eat less preserving and
processed food such as sausages, pickles and
potato ch ips.
3. Drink less caffeinated beverages like
strong tea, coffee and coke.
This information leaflet is for reference only.
4. Do moderate exercise regularly.
Medicines should be used as directed by

S. Keep optimal body

the doctor.

6. Learn self-relaxation For enquiry, please consult your doctor or

because anxiety, dispensing staff

loss of temper and

Do not share your medicine with others.
overstrain all give
rise to increased blood

Drug Office
Department of Health