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The

Gulf War Illness Research Program (GWIRP) (DoD-CDMRP)


PREPARED BY: VETERANS FOR COMMON SENSE. Last Updated March 14, 2017


GWIRP Vision: Improve the health and lives of veterans who have Gulf War Illness.1
GWIRP Mission: Fund innovative Gulf War Illness research to identify effective treatments,
improve definition and diagnosis, and better understand pathobiology and symptoms.1

The Gulf War Illness Research Program (GWIRP), one of the many military-related
Congressionally Directed Medical Research Programs (CDMRP) within the U.S. Department of
Defense (DoD) health program, is a unique treatment development medical research program
initiated by Congress in FY06 to support medical research of exceptional scientific merit related
to the deployment health effects of the 1991 Gulf War (Operation Desert Storm).1
GWIRP is unique:
Intramural vs. Extramural: VA only funds VA researchers (an intramural program); CDMRP
is not similarly constrained (an extramural program) and aims to find and fund the best
research proposals by government, academic, or even industry researchers.
Treatment-Focused: The GWIRP is the only federal program ever to exist that is solely
focused on funding research to develop treatments for Gulf War Illness (GWI), including
funding the necessary preclinical work to understand pathobiology and etiology as they
pertain to treatment development a bench-to-bedside model for other environmental
injuries and Toxic Wounds.
Peer-Reviewed: The best medical research is found and funded via a strategically directed,
competitively selected, two-tier peer review process1
Emphasizes collaboration: The GWIRP continues to fund interdisciplinary and inter-
institutional research collaborations to better solve complex issues than by single
researchers working alone.
Uses Consumer Reviewers1,5: Affected patients who offer insight, focus, urgency, and
impact are included at every level of program development and proposal review. This
ensures ill Gulf War veterans have a say in what research is funded that may directly
affect them.
Funding: Congressionally directed via annual Defense (DoD) appropriations bills.

ABOUT GULF WAR ILLNESS (GWI): GWI is characterized by multiple, diverse symptoms that
typically include chronic headache, widespread pain, cognitive difficulties, debilitating fatigue,
gastrointestinal problems, respiratory symptoms, sleep problems, and other abnormalities that
could not be explained by established medical diagnoses or standard laboratory tests. The
population of Veterans affected by GWI is a subset of the nearly 700,000 U.S. Warfighters who
served during the 1990-1991 Gulf War. Studies indicate that approximately 25-32% of Gulf War
Veterans continue to experience symptoms associated with their deployment.1 Scientific
research . . . supports and further substantiates . . . that Gulf War illness is a serious physical
disease, affecting at least 175,000 veterans of the 1990-1991 Gulf War, that resulted from
hazardous exposures in the Gulf War theater.3 (p.1)
Studies and surveys reviewed in the most recent (2014) RAC report indicated an elevated
prevalence of Lou Gehrigs disease (ALS)3(pp.23-25) and elevated rates of diagnosed migraines,
seizures, gastrointestinal conditions, respiratory conditions and skin disorders among Gulf War
veterans, and doubled brain cancer3(pp.23-26) death rates among veterans potentially exposed to
chemical warfare agents detonated at an Iraqi munitions complex at Khamisiyah, Iraq.

NEED AND SUPPORT FOR THE GWIRP: Reports by the National Academy of Sciences Institute
of Medicine (IOM)2 (pp. 10, 260-64) and the Congressionally-mandated VA Research Advisory
Committee (RAC) on Gulf War Veterans Illnesses3 (pp. 1, 4, 5, 13, 78, 83) emphasize that effective
treatments, cures, and, it is hoped, preventions for GWI can likely be found, through a
concerted national effort and rigorous scientific input. 2 (p. 10) In addition, important
discoveries made by the GWIRP may also help protect current and future U.S. military service
members at risk of similar toxic exposures. (RAC 2014, pp. 1, 4, 5, 13, 78, 83; IOM 2010, pp. 10, 260-64.)

The RAC,3 more than 50 FY15 Independent Budget Veterans Service Organizations (IBVSOs),4
scientist GWIRP panelists,1,5 and numerous consumer reviewers serving with the GWIRP1,5,6
have expressed strong support for the GWIRP to improve the health and lives of veterans
suffering from GWI. The FY15 IBVSOs said the GWI CDMRP, has made great strides in the
short time it has been operating,4 (pp. 126-27) and the IBVSOs (DAV, PVA, VFW, and 27 others) for
the 115th Congress (2017-18) are asking Congress to provide sufficient funding to resume
robust research to identify effective treatments...7 (pp. 92-93)

FY17 GWIRP Funding Supported by: American Legion; AMVETS; Association of the U.S. Navy
(AUSN); Burnpits360; Disabled American Veterans (DAV); Lung Cancer Alliance; National Gulf
War Resource Center (NGWRC); National Vietnam & Gulf War Veterans Coalition (NVGWVC);
Paralyzed Veterans of America (PVA); Sergeant Sullivan Circle; Toxic Wounds Task Force;
Veterans for Common Sense (VCS); Veterans of Foreign Wars (VFW); Vietnam Veterans of
America (VVA).

GWIRP past annual funding levels:1
FY06: $5m
FY08: $10m Recommendations, 2009-2013. Washington, D.C.:
U.S. Government Printing Office, May 2014.
FY09-FY11: $8m www.va.gov/RAC-GWVI/RACReport2014Final.pdf
FY12: $10m 4
Independent Budget Veterans Service
FY13-FY17: $20m (current) Organizations (IBVSOs), The Independent Budget
for the Department of Veterans Affairs: Fiscal Year
2015.
1 Gulf War Illness Research Program (GWIRP)
www.independentbudget.org/2015/IB_2015.pdf.
website, Congressionally Directed Medical Research 5
GWIRP program booklet, Gulf War Illness
Program (CDMRP), U.S. Army Medical Research and
Research Program, April 2014.
Materiel Command, U.S Department of Defense
http://cdmrp.army.mil/gwirp/pbks/gwirppbk2014.pdf.
(DoD): http://cdmrp.army.mil/gwirp 6 GWIRP program booklet, April 2016.
2 Institute of Medicine (IOM), National Academy of
http://cdmrp.army.mil/gwirp/pbks/gwirppbk2016.p
Sciences, Gulf War and Health, Volume 8: Update of df
Health Effects of Serving in the Gulf War, 7
Washington, DC: The National Academies Press,
IBVSOs, The Independent Budget Veterans
th
2010. www.nap.edu/catalog/12835/gulf-war-and- Agenda for the 115 Congress: Policy
Recommendations for Congress and the
health-volume-8-update-of-health-effects
3 Research Advisory Committee on Gulf War Administration.
http://www.independentbudget.org/2018/FY18_IB.
Veterans' Illnesses (RAC), U.S. Department of
pdf
Veterans Affairs, Gulf War Illness and the Health of
Gulf War Veterans: Research Update and
2

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