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following traumatic rupture of capsule, most common type. College and General Hospital, Ananthapuramu, India
2.Anterior subluxation or dislocation of lens and spherophakia.
Swollen lens pushes the iris forward and obliterate the angle Corresponding author: Dr. P. Sreenivasulu M.D., Associate Professor,
Department of Ophthalmology, Government Medical College,
resulting in secondary acute angle closure glaucoma further the
Ananthapuramu - 515001, Andhra Pradesh, India
increased iridolenticular contact also causes potential pupillary
block and iris bombe formation.4 How to cite this article: P. Sreenivasulu, Y.M.S. Prasad. Assessment
Medical treatment to control IOP by IV mannitol. Systemic of risk factors for developing phacomorphic glaucoma. International
acetazolamide or topical B blockers are also effective to Journal of Contemporary Medical Research 2016;3(7):2014-2016.
2014
International Journal of Contemporary Medical Research
Volume 3 | Issue 7 | July 2016 | ICV: 50.43 | ISSN (Online): 2393-915X; (Print): 2454-7379
www.ijcmr.com
socioeconomic status were entered into excel sheet. Cases and where its pathophysiology is secondary angle closure glaucoma
controls affected eyes were examined by measuring Intraocular that may occur as result of hyper mature cataract formation.
Pressure, axial length, anterior chamber depth, Both eyes Gifford has recommended before cataracts changes to
corrected visual acuity (BCVA). hypermature, early extraction of lens is needed.6
Intra ocular Pressure (IOP) was measured using Goldman Risk factors responsible for phacomorphic Glaucoma are age
Applanation Tonometry, BCVA was assessed by using Snellen above 60 years4,7, female gender7,8, Axial length <23.7 mm3,
chart and Both Axial length and anterior chamber depth was narrow anterior chamber.9
measured using contact A-scan ultrasonography at this tertiary In the present study the mean age of Group 1 was 68.85.2 and
care hospital Axial length and anterior chamber depth was Group 2 was 69.43.05. Most of the patients were under upper
measured by two optometrists and an average of ten readings lower (42.5%) followed by lower middle class (30%). Lee JW et
was considered. al4 observed the incidence of Phacomorphic glaucoma is more
in above 60 years age group and female gender, as in correlation
STATISTICAL ANALYSIS
with the present study. Low Socioeconomic group people are
Statistical analysis was done using Graph pad software, as the predominantly affected by Phacomorphic glaucoma.11,2
p value <0.05 were considered significant. Descriptive analysis The Mean Intra ocular pressure of Phacomorphic glaucoma was
was used to infer results. 47.67.3 mmHg and of mature cataract was 15.28.5 mmHg in
RESULTS this study. Diagnosis of glaucoma mainly by IOP measurement
above 21 mmHg12, whereas average of presenting is above 40
In this prospective study, 40 cases and 40 controls were
mmHg.1,13 Gonioscopy is a good diagnostic method for the
considered with phacomorphic glaucoma and mature cataract
diagnosis of Phacomorphic glaucoma, but it should not use in
without phacomorphic glaucoma respectively.
the presence of corneal edema from the acute IOP elevation.1
All the studied population were selected in the age group of
Lee JW et al4 observed that the mean IOP among Phacomorphic
40-90 years. Cases and Control groups were considered such
glaucoma was 49.511.8 mmHg and among control eyes were
that M:F ratio was 1:1. The mean age of Group 1 was 68.85.2
16.71.7 mmHg.
and Group 2 was 69.43.05 (Table-1). Socioeconomic Status
On BCVA assessment using Snellen chart shown poorer
was analyzed by considering fathers education, income and
visual acuity among Phacomorphic glaucoma (Group 1) when
occupation. Most of the patients were under upper lower
compared to mature cataract (Group 2). It was Light perception
(42.5%) followed by lower middle class (30%).
among Phacomorphic glaucoma patients and Hand movement
On BCVA assessment using Snellen chart shown poorer
was observed in mature cataracts without phacomorphic
visual acuity among phacomorphic glaucoma (Group 1) when
glaucoma as per this study. Visual acuity among Phacomorphic
compared to mature cataract (Group 2). It was Light perception
glaucoma in this study is similar to Lee JW et al4 documented
among Group 1 and Hand movement was observed in Group
as there is poor vision between acute attack and dense cataract,
2. Axial length and Anterior Chamber Depth were lesser in
averaging light perception only.
Phacomorphic Glaucoma when compared to Mature cataract
In this study Axial length and Anterior Chamber Depth were
(Table-2). Axial length was statistical significance in between
lesser in Phacomorphic Glaucoma when compared to Mature
group 1 and 2. There was no statistical significant difference of
cataract. Axial length was statistical significance in between
Anterior chamber depth between phacomorphic glaucoma and
group 1 and 2. There was no statistical significant difference
mature cataract.
of Anterior chamber depth between phacomorphic glaucoma
DISCUSSION and mature cataract. Lee SJ et al1 reported that anterior chamber
Phacomorphic glaucoma is a type of lens induced glaucoma, depth is less than 2mm. IN contrast the study Tomey KF et
al14 documented that Either shallow or deep anterior chamber
Characteristics Group 1 (n=40) Group 2 (n=40) cause phacomorphic glaucoma. Short axial length in relation
Age 68.85.2 69.43.05 to primary angle closure glaucoma, like short axial length
Sex decreases while the risk of primary angle closure gets doubled.14
Males 14 14 It is supported by many studies.15,4
Females 26 26 Main treatment of Phacomorphic glaucoma is by extraction of
Socioeconomic status (Modified Kuppuswamy's Classification) cataractous lens. Treatment is the main goal to reduce the IOP,
Upper 0 0 which in turn eliminates the symptoms related to Glaucoma.
Upper Middle 2 5% Surgical treatment may delay in such conditions where there is
Middle/Lower Middle 9 22.5% an acute attack presenting with corneal edema and High IOP. In
Upper Lower 17 42.5% such conditions need to stabilize the eye by medical treatment,
Lower 12 30% later can go with removal of cataractous lens. Medical treatment
Intra Ocular Pressure 47.67.3 mmHg 15.28.5 mmHg includes Beta blockers, alpha -agonists and carbonic anhydrase
Table-1: Various Demographic features of studied population inhibitors.16 Argon Laser Peripheral Iridoplasty also can be used
to reduce IOP, has few side effects than oral or intravenous Surg. 2010; 36:783-789.
acetazolamide and hyperosmotics.17 Before cataract extraction 13. Tomey KF, al-Rajhi AA. Neodymium: YAG laser iridotomy
needs to reduce the IOP by using Intravenous mannitol.7,18 in the initial management of phacomorphic glaucoma.
Ophthalmology. 1992;99:660-5.
CONCLUSION 14. Casson RJ, Baker M, Edussuriya K, Senaratne T, Selva
Phacomorphic glaucoma usually results in elderly age, short D, Sennanayake S. Prevalence and determinants of angle
axial length or shallow anterior chamber individuals. Raise closure in central Sri Lanka: The Kandy Eye Study.
Ophthalmology. 2009;116:1444-9.
in Intraocular Pressure is the one responsible for symptoms.
15. Oku Y, Oku H, Park M, Hayashi K, Takahashi H, Shouji
Axial length measurement is a easy predictor for diagnosing
T, et al. Long axial length as risk factor for normal
phacomorphic glaucoma. tension glaucoma. Graefes Arch Clin Exp Ophthalmol.
Health education in community regarding complications 2009;247:781-7.
of cataractous lens will avoid them facing problems due to 16. Sowka J. Phacomorphic glaucoma: case and review.
phacomorphic glaucoma. Many organizations are conducting Optometry. 2006;77:586-589.
free camps for extraction of cataract, which is a definite 17. Tham CC, Lai JS, Poon AS, Chan JC, Lam SW, et al.
treatment for phacomorphic glaucoma. Screening of all elderly Immediate argon laser peripheral iridoplasty (ALPI) as
age group in communities is necessary to reduce the incidence initial treatment for acute phacomorphic angle-closure
of phacomorphic glaucoma and other lens induced glaucoma (phacomorphic glaucoma) before cataract extraction: a
and also require regular follow-ups to achieve good prognosis preliminary study. Eye (Lond). 2005;19:778-783.
18. Ramakrishanan R, Maheshwari D, Kader MA, Singh
by reducing IOP.
R, Pawar N et al. Visual prognosis, intraocular pressure
ACKNOWLEDGMENTS control and complications in phacomorphic glaucoma
following manual small incision cataract surgery. Indian J
We would like to express our gratitude towards the staff of
Ophthalmol. 2010;58:303-306.
Department of Ophthalmology for cooperating us while doing
this study.
Source of Support: Nil; Conflict of Interest: None
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2016
International Journal of Contemporary Medical Research
Volume 3 | Issue 7 | July 2016 | ICV: 50.43 | ISSN (Online): 2393-915X; (Print): 2454-7379