Herbal Therapy: Aloe Vera, the Natural Whole Food Medicine

for Reduced Aging Wrinkle

Aloe Vera is species of succulent plant in the genus Aloe, belonging to the
Family Xanthorrhoeaceae, native to Sudan. It is very popular for commercial
cultivation due to its health benefits, used in herbal medicine in treating many
kinds of disease, including wound, burn healing, minor skin infections,
sebaceous cysts, diabetes, and elevated of cholesterol, etc.

Wrinkle is a skin degenerative condition caused by the loss of dermis and
subcutaneous fat layer underneath the skin, leading to a slight line or fold on
the skin, particular in the face.

According to the Food Ingredients & Technology Institute, daily oral intake of
plant sterols of Aloe vera gel (Aloe sterol) significantly increases the skin
barrier function, moisture, and elasticity in photoprotected skin of that may
reduce risk of skin wrinkle.

In a 12-week, randomized, double-blind, placebo-controlled study, in 48
apparently healthy men (age range: 30-59 years; average: 45 years), intake of
oral Aloe sterol supplementation after 12 weeks showed a significant
improvement of the skin elasticity index in comparison in the baseline value .

Dr. Tanaka M, the lead author said, "Aloe sterol ingestion increased skin
elasticity in the photodamaged skin of men aged <46 years, and "No Aloe sterol
intake-dependent harmful phenomenon was observed during the intake period".

Furthermore, in vitro, Aloe sterols increased production of collagen and
hyaluronic acid, natural substance in skin response to connective, epithelial,
and neural tissues. approximately two-fold and 1.5-fold, and promoted gene
expression levels in human dermal fibroblasts.

In fact, daily oral Aloe sterol-containing Aloe vera gel powder (AVGP)
significantly reduced facial wrinkles in women aged ≥40 years as well as
stimulated collagen and hyaluronic acid production by human dermal

In support of the above evaluation, intake of Aloe Vera gel enhanced healthy
skin through promoting elasticity (R2), net elasticity (R5), and biological
elasticity (R7) scores and skin fatigue area F3,the Food Ingredients and
Technology Institute 12 weeks study suggested.

Taking altogether, there is no doubt that oral administration of Aloe Vera or
Aloe Vera supplements may improve skin condition caused by skin aging
degeneration, but quality of amount intake should only be prescribed by related
field specialist.

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(1) Effects of plant sterols derived from Aloe vera gel on human dermal
fibroblasts in vitro and on skin condition in Japanese women by Tanaka M1,
Misawa E1, Yamauchi K1, Abe F1, Ishizaki C2.(PubMed)
(2) Effects of Aloe Sterol Supplementation on Skin Elasticity, Hydration, and
Collagen Score: A 12-Week Double-Blind, Randomized, Controlled Trial by
Tanaka M1, Yamamoto Y, Misawa E, Nabeshima K, Saito M, Yamauchi K, Abe
F, Furukawa F.(PubMed)
(3) Aloe sterol supplementation improves skin elasticity in Japanese men with
sunlight-exposed skin: a 12-week double-blind, randomized controlled trial by
Tanaka M1, Yamamoto Y2, Misawa E1, Nabeshima K1, Saito M1, Yamauchi
K1, Abe F1, Furukawa F2.(PubMed)