Name of Drug Lipitor *Atorvasta tin Calcium* Classification and Mechanism of Drug Antihyperlipide mic Inhibits HMG – CoA reductase, an early step in cholesterol biosynthesis Indication and Dosage *Adjunct to diet reduce LDL, total cholesterol, apolipoprotein B, and triglyceride levels and to increase HDL levels in patients with primary hypercholesterol emia Adults: Initially 10 or 20mg PO once daily *To reduce the risk of stroke Adults: 10mg PO daily Contraindication Side Effects/Adve rse Reaction CNS: headache, asthenia, insomnia CV: peripheral edema EENT: rhinitis, pharyngitis, sinusitis GI: abdominal pain, dyspepsia, flatulence, nausea, constipation Musculoskelet al: arthritis, athralgia, myalgia Respiratory: bronchitis Skin: rash Nursing Responsibilities

1.Contraindicated in patients hypersensitive to drug and in those with active liver disease. 2. Contraindicated in pregnant and breastfeeding women and in women of childbearing. 3. Use cautiously in patients with history of liver disease or heavy alcohol use. 4. Withhold or stop drug in patients at risk for renal failure caused by rhabdomyolysis

1. Teach patient about proper dietary management, weight control and exercise. 2. Warn patient to avoid alcohol. 3. Tell patient inform prescriber of adverse reactions such as muscle pain, malaise and fever. 4. Advise patient that drug can be taken at any time of day, without regard to meals. 5. Before starting treatment, assess patient for underlying causes for hypercholesteromia and obtain a baseline lipid profile. 6. Patient should follow a standard low – cholesterol diet before and during


Name of Drug
Ziac *hydrochlorothiazide and bisoprolol fumarate*

Classification and Mechanism of Drug
Antihypertensive First line therapy in mild to moderate hypertension

Indication and Dosage
Hypertension Adults: 2.5mg / 6.25mg tab PO daily. Increase or decrease daily dose based on blood pressure.

Contraindicatio n
Use in bronchospastic pulmonary disease, cardiogenic shock, overt CHF, hypersensitivity to either drug or to other sulfonamide derived drugs, during lactation

Side Effects/Adverse Reaction
serious side effects:  swelling, rapid weight gain, feeling short of breath, even with mild exertion  fast, slow, or uneven heartbeat  chest pain  easy bruising or bleeding  sudden numbness or weakness on one side of the body, problems with vision or speech, chest pain, or pain in one or both legs;

Nursing Responsibilities

1. Do not perform activities that require mental alertness until drug effects realized. 2. Report sign and symptoms of heart failure (increase edema, fatigue) as alternative therapy may be indicated

3. Diabetics should monitor
blood sugar carefully as beta blockers may mark symptoms of hypoglycemia 4. Monitor vital signs carefully

5. Assess ECG to ensure no
dysrhythmias (second – or third degree AV block or bradycardia) that would preclude drug therapy

 numbness or tingly feeling in your hands or feet less serious • diarrhea, constipation, upset stomach; • headache, tired feeling; • dizziness, spinning sensation; • cough, runny nose;

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