RNA VIRAL GENOMES

I. THE NON-ENVELOPED, PLUS-STRAND RNA VIRUSES (TYPE IV)

PICORNAVIRIDAE 7-8 KB
5'-VPg, IRES (750 N) POLIOVIRUS, HAV
3' POLY-A RHINOVIRUS
CALICIVIRIDAE 8 KB
5'-VPg mRNA LEADER NOROVIRUS
3'-POLY A [HEV]

II. THE ENVELOPED, PLUS-STRAND RNA VIRUSES (TYPE IV)

FLAVIVIRIDAE 9-13 KB
5'-CAP (FLAVIVIRUSES) ? c IRES (OTHERS) YEL FEV V, SLEV
3'-LARGE NTR, LONG STEM-LOOP WNV, TBEV, HCV
TOGAVIRIDAE 10-12 KB
5'-CAP EEEV,WEEV,WEEV
3'-POLY-A RUBELLAVIRUS
CORONAVIRIDAE ~30 KB (~20 FOR TORO-)
(LARGEST RNA GENOMES)
5'-CAP, 60 N LEADER HUMAN CORNA V
3'-POLY-A

III. THE DOUBLE-STRAND RNA VIRUSES: REOVIRIDAE (TYPE III)

10-12 DS RNA SEGMENTS
5'-CAP (PLUS STRAND ONLY) ROTAVIRUS
3'- (NO POLY-A) [CONSERVED END SEQS]

IV. THE MONONEGAVIRALES: SINGLE, MINUS-STRAND RNA VIRUSES (TYPE V)

RHABDOVIRIDAE
ROD-SHAPED, TRANSCRIPTION-STUTTERING, RABIES V
REPLICATION, FIVE GENES: N-P-M-G-L
FILOVIRIDAE
FILAMENTOUS, DITTO EBOLA V
RNA EDITING OF G PROTEIN mRNA MARBURG V
PARAMYXOVIRIDAE
SPHERICAL-SHAPED, DITTO MUMPS/MEASLES V
RNA EDITING & ALT. START OF P/V/C RSV, PARAFLU V

V. THE SEGMENTED, MINUS-STRAND AND AMBISENSE VIRUSES (TYPE V)

ORTHOMYXOVIRIDAE
8 RNA SEGMENTS, 10 PROTEINS, H & N TYPES INFLUENZA
CAP SNATCHING, ANTIGENIC DRIFT & SHIFT A, B & C VIRUS
BUNYAVIRIDAE
3 SEGMENTS, SOME VIRUSES ARE ABISENSE HANTA V, CEV
USU. SINGLE PROTEIN FROM EACH SEGMENT SIN NOMBRE V
ARENAVIRIDAE
2 SEGMENTS, BOTH AMBISENSE LASSA VIRUS
EACH RNA CODES FOR 2 PROTEINS (L,Z;N,G) TACARIBE V