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Alternative names

Pleuritis; Pleuritic chest pain


Pleurisy is an inflammation of the lining of the lungs that causes pain when you take a breath or

Causes, incidence, and risk factors

Pleurisy may develop when you have lung inflammation due to infections such as pneumonia
or tuberculosis. It may also occur with rheumatic diseases, chest trauma, certain cancers, and
asbestos-related disease.

When you have pleurisy, the normally smooth lining of the lung (the pleura) become rough. The
rub together with each breath, and may produce a rough, grating sound called a "friction rub."
This sound can be heard with the stethoscope, or when you place an ear against the patient's


The main symptom of pleurisy is pain in the chest. Sometimes the pain may be felt in the

Deep breathing, coughing, and chest movement makes the pain worse.

Pleurisy causes fluid to collect inside the lung area. This makes breathing difficult and may cause
the following symptoms:

• Coughing
• Shortness of breath
• Rapid breathing (tachypnea)
• Cyanosis

Signs and tests

The doctor will use a stethoscope to listen to the lungs for abnormal sounds.

• Friction rub is a rough scratchy sound

• Rales may be occur with pneumonia
• Rhonchi may occur with pneumonia or bronchitis
• Decreased breath sounds may indicate fluid around the lung

The following tests may be performed:

• CBC (may help determine if the infection is caused by a bacteria or virus)
• X-ray of the chest
• Ultrasound of the chest
• Thoracentesis (a collection of fluid from the chest cavity)


Treatment depends on what is causing the pleurisy. Bacterial infections are treated with
antibiotics. Viral infections normally run their course without medications. Fluid in the lungs may
be removed by thoracentesis and checked for signs of infection. The pain of pleurisy can often be
controlled with acetaminophen or anti-inflammatory drugs such as ibuprofen.

Expectations (prognosis)

Recovery depends on what is causing the pleurisy.


• Breathing difficulty
• Complications associated with the original illness
• Collapsed lung due to thoracentesis

Calling your health care provider

Call your health care provider if you have symptoms of pleurisy. If you have breathing difficulty or
the skin turns blue, seek immediate medical care.


Early treatment of bacterial respiratory infections can prevent pleurisy.


Marx J. Rosen’s Emergency Medicine: Concepts and Clinical Practice. 5th ed. St. Louis, Mo:
Mosby; 2002:1005.

Murray J, Nadel J. Textbook of Respiratory Medicine. 3rd ed. Philadelphia, Pa: WB Saunders;
2000: 497-498.