From the Physicians Committee for Responsible Medicine / Summer 2010 / Vol. XIX, No. 3
Beyond Mice and Monkeys
PCRM Conference Explores Alternatives to Animal Research
VaxDesign’s MIMIC System
Athletes, Celebrities Ask Congress for Healthier School Meals • Facial Expressions of Mice in Pain • Double Down or Double Bypass? • BEST Practices Act Gains New Supporters • Five Foods to Avoid at Mexican Restaurants • The Anti-Arthritis Diet • PCRM Confronts NASA Monkey Experiments
New Science Demands Stronger Protections
yumu lives in Kyoto, Japan. At just 7 years of age, he made quite a name for himself. He sidled up to a computer at Kyoto University. On the screen, the numbers 1 through 9 appeared in random order. He touched each number in sequence as he had been taught to do. The numbers then appeared in new positions, and again, Ayumu touched each one in the correct numerical sequence. But then things got harder. The newly scrambled numbers appeared again, but only for a fraction of a second before being replaced by blank squares, and Ayumu had to remember where the numbers had been. He still touched the squares where the numbers had been in exactly the right order. He did it over and over again, with amazing accuracy. Researcher Tetsuro Matsuzawa, Ph.D., then pitted Ayumu against university students several times his age. Ayumu’s memory was far more accurate than the students’. Then British memory champion Ben Pridmore, a 30-year-old accountant from Derby who can memorize the order of a shuffled pack of cards in 30 seconds, took his turn against Ayumu. He was no match. In fact, no human was a match for Ayumu. Ayumu is a chimpanzee. For some evolutionary reason, chimpanzees have developed an extremely acute short-term memory, far beyond that with which humans are equipped. Biologists have come to recognize that animals—even those we think of as humble—have many capabilities that are greater than we had appreciated. Squids decipher the colored communication patterns that radiate up and down each others’ sides. Dogs detect smells and sounds that are out of humans’ detection range. Starlings coordinate their flights millisecond by millisecond in ways that make human aviators look absolutely clumsy. These neurological differences have fueled many Ph.D. dissertations and countless television documentaries. But in the world of research ethics, these issues are much more than theoretical. Earlier this year, researchers showed that mice grimace in pain, very much the way humans do. If mice feel pain as much as we do, what does this tell us about how animal research should be regulated? If chimpanzees retain an intensely acute memory for recent events, what sorts of protections do they need against psychological trauma? Up until now, animal protection guidelines have stacked species on a crude scale of biological value. Those at the top of the scale were protected; those at the bottom were not. Biologists now know that such hierarchies have no scientific basis. So what shall we do? The U.S. Animal Welfare Act currently requires investigators to consider alternatives, a task that is often reduced to a checked box on a research application. It is now clear that is not good enough. Researchers need to really consider alternatives, and they need to implement them. And when alternatives are not readily available, they need to Up until now, animal pursue them. protection guidelines have PCRM researchers did exactly that in developing a new test for measuring stacked species on a crude human insulin levels. Previous methods used animals essentially as living antibody factories, inserting clusters of cells in their abdomens that triggered the production scale of biological value. of massive amounts of abdominal fluid, which was tapped off with needles, along with the antibodies it contained. So when we set out to develop a better method, using cells instead of animals, we were told it was not possible. As it turned out, it did take some time and money. But our new insulin assay turned out to be better, not just ethically, but also technically, and is now the industry standard. As physicians and scientists, we cannot ignore what animal behaviorists have shown us. Rather, we need to embrace new and better research methods that allow science to progress without suffering.
Neal D. Barnard, M.D. President of PCRM 2
GOOD MEDICINE Summer 2010
From tHE pHySiCianS CommittEE For rESponSiblE mEdiCinE
Editor in Chief Neal D. Barnard, M.D. Managing Editor/Designer Doug Hall Editor Carrie Mumah Associate Editor Patrick Sullivan Production Manager Lynne Crane Senior Web Designer Lisa Schulz
ADviSOrY BOArD T. Colin Campbell, Ph.D. Cornell University Caldwell B. Esselstyn, Jr., M.D. The Cleveland Clinic Henry J. Heimlich, M.D., Sc.D. The Heimlich Institute Suzanne Havala Hobbs, Dr.P.H., M.S., r.D. University of North Carolina–Chapel Hill Lawrence Kushi, Sc.D. Kaiser Permanente John McDougall, M.D. McDougall Program virginia Messina, M.P.H., r.D. Nutrition Matters, Inc. Milton Mills, M.D. Gilead Medical Group Myriam Parham, r.D., C.D.E., C.L.C. Florida Hospital Zephyrhills William roberts, M.D. Baylor Cardiovascular Institute Andrew Weil, M.D. University of Arizona Affiliations are listed for identification only.
PCRM STAFF • Kristin Adair Public Affairs Associate & Legislative Counsel • Nancy Beck, Ph.D. Scientific and Policy Adviser • Noelle Callahan Research Program Coordinator • Lynne Crane Production Manager • Cael Croft Associate Designer • Claudia Delman, M.P.H. Outreach Manager • Debra Durham, Ph.D. Senior Research Scientist • Jill Eckart, C.H.H.C. Assistant to the President • Leah Engel Executive Assistant • Tara Failey Communications Coordinator • Hope Ferdowsian, M.D., M.P.H. Director of Research Policy • Rebecca Frye Research Program Coordinator • Jessica Frost Communications Coordinator • Noah Gittell Research and Education Programs Coordinator • Doug Hall Publications Director • Vaishali Honawar Communications Coordinator • Patricia Howard Advertising and PSA Manager • Michael Keevican Web Editor/Staff Writer • Mark Kennedy, Esq. Associate General Counsel • Dan Kinburn, Esq. General Counsel • Leah Koeppel Nutrition and Research Assistant • Elizabeth Kucinich Director of Public Affairs • Ruby Lathon, Ph.D. Nutrition Policy Manager • Susan Levin, M.S., R.D. Director of Nutrition Education • Lynn Maurer Associate Designer • Jeanne Stuart McVey Media Relations Manager • Ryan Merkley Manager of Research and Education Programs • Carrie Mumah Staff Writer • John Pippin, M.D. Senior Medical and Research Adviser • Chip Rogers Legislative Director • Leslie Rudloff, Esq. Senior Counsel • Chad Sandusky, Ph.D. Director of Toxicology and Regulatory Testing • Lisa Schulz Web Designer • Kathryn Strong, M.S., R.D. Dietitian • Kristie Sullivan, M.P.H. Scientific and Policy Adviser • Patrick Sullivan Director of Communications • Caroline Trapp, M.S.N., A.P.R.N., B.C.-ADM, C.D.E. Director of Diabetes Education and Care • THE CANCER PROJECT • Joseph Gonzales, R.D. Dietitian • Sanjay Jain Educational Program and Volunteer Coordinator • Lauray MacElhern Managing Director • Dawnyel Pryor Marketing Manager • Emily Richard Educational Program Manager • PCRM FOUNDATION • Nabila Abdulwahab Data Processor • Bruce Banks Staff Accountant • Melinda Beard Receptionist • Nikki Bollaert, M.N.M., C.F.R.E., C.A.P. Director of Special Gifts • Deniz Corcoran Data Entry Manager • Sossena Dagne Data Processor • John Evans Database/Web Developer • Riva Gebel Major Gifts Officer • Stacey Glaeser Director of Human Resources • Erica Hanna Information Technology Manager • Lesley Hill Budget Coordinator • Stephen Kane Finance Director • Jacqueline Keller Development Assistant • JohnR Llewellyn Internet Marketing Manager • Garron Marsh Facilities Coordinator • Andria Matrone Membership Assistant • Debbi Miller Special Events Manager • Eden Mohammed Office Services Coordinator • Margaret Murray Major Gifts Officer • John Netzel Facilities Manager • Will Oliver Literature Fulfillment Coordinator • Manali Patel Staff Accountant • Sarah Petersen Human Resources Coordinator • Kalpesh Suthar Accounts Payable Coordinator • Betsy Wason, C.F.R.E. Director of Development • Rod Weaver Data Manager • Christopher Wright Finance Assistant • Craig Ziskin Associate Director of Annual Giving • WASHINGTON CENTER FOR CLINICAL RESEARCH • Jia Xu, Ph.D. Clinical Research Coordinator • Kavita Rajasekhar, M.D. Clinical Research Coordinator • CONSULTANTS • Jarrod Bailey, Ph.D. • Jonathan Balcombe, Ph.D. • Laura Beck • Michelle Cehn • Elizabeth Cummings • Amber Green, R.D. • Jennifer Huff • Amy Lanou, Ph.D. • Paul Marcone • Suzan Porto • Jennifer Reilly, R.D. • Garrett Strang Good Medicine is published quarterly by the Physicians Committee for Responsible Medicine, 5100Wisconsin Ave., NW, Suite 400,Washington, DC 20016, tel 202-686-2210, fax 202-686-2216. It is distributed as a membership benefit to PCRM members. Basic annual membership in PCRM is $20 (tax-deductible). PCRM promotes good nutrition, preventive medicine, ethical research practices, and compassionate medical policy. Readers are welcome to reprint articles without additional permission. Please include the credit line: Reprinted from Good Medicine, Summer 2010, Physicians Committee for Responsible Medicine. Articles are not to be reprinted for resale. Please contact PCRM at permissions@ pcrm.org regarding other permissions. ©PCRM 2010. Good Medicine is not intended as individual medical advice. Persons with medical conditions or who are taking medications should discuss any diet and lifestyle changes with their health professional. “Good Medicine” is a registered trademark of the Physicians Committee for Responsible Medicine. “Physicians Committee for Responsible Medicine,”“PCRM,”“The Cancer Project,” “Humane Charity Seal,” and “The Gold Plan” are trademarks of PCRM, federal registration pending.
Vol. XIX, No. 3
6 Beyond Mice and Monkeys: PCRM Conference Explores Alternatives to Animal Research 8 PCRM Confronts NASA Monkey Experiments Facial Expressions of Mice in Pain 9 Doctor Files Complaint Over Tulane’s Pig Lab New Society Promotes Nonanimal Chemical Testing 10 PCRM in East Africa
nutrition and prevention
10 PCRM’s New Doctor’s Office Outreach Program 11 Get Healthy, Go Vegan with Dr. Barnard’s New Cookbooks Double Down or Double Bypass? Kickstart Your Diet 12 The Anti-Arthritis Diet PCRM Helps Improve D.C. School Nutrition
pCrm legislative Fund
13 Advancing the PCRM Mission Pamela Anderson Supports Great Ape Protection Act 14 Pushing for Better Test Methods BEST Practices Act Gains New Supporters 15 Athletes, Celebrities Ask Congress for Healthier School Meals Hollywood Supports Healthy School Meals Act
the Cancer project
16 The Cancer Project Update Five Foods to Avoid at Mexican Restaurants 17 The News You Need
4 18 20 23 24
The Latest in... Member Support 25th Anniversary PCRM Gala / Award Winners PCRM Marketplace Just the Facts Physician Profile A Star Pediatrician: Jay Gordon, M.D. CovEr poStEr: vaxdESiGn / iStoCKpHoto
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Doctors and laypersons working together for compassionate and effective medical practice, research, and health promotion.
Summer 2010 GOOD MEDICINE
the latest in…
the latest in…
By Kristie Sullivan, M.P.H.
nonanimal neurotoxicity model Shows promise
human neurodevelopmental diseases, such as autism spectrum disorder. In the EPA laboratories in North Carolina, Josh Harrill, Ph.D., is working to model in a test tube all the ways neural cells can be disturbed by toxins. Putting these models together will help scientists determine how a chemical might affect the developing nervous system. His work with an assay that measures lack of neurite outgrowth from neural cells uses human cells, which he found were more sensitive to neurotoxins than were rat cells. Preliminary tests with several different neurotoxins known to inhibit neurite outgrowth show this model to be a promising step in developing a nonanimal method.
Presented at the Society of Toxicology annual meeting, March 2010.
scientist with the Environmental Protection Agency is working on a strategy to replace neurotoxicity testing on animals. The developmental neurotoxicity test typically involves dosing pregnant animals with chemicals and then testing their offspring for neurodevelopmental defects. While the test is intended to detect chemicals that might be harmful to a child’s developing neural system, it is difficult to link results of these tests to
Europe’s new Guide on avoiding animal testing
he European Chemicals Agency (ECHA) recently published a guide to help industry avoid animal testing. ECHA is implementing Europe’s new chemical regulation REACH, which will require companies around the world to perform tests on their chemicals—including animal tests. Following meetings in which PCRM and other organizations pushed the agency to do more to prevent animal testing, it has published a series of six practical guides for using nonanimal alternatives and an overall guide on avoiding animal testing. The agency has also promised consequences
new Strategy Could reduce animal-based Cancer tests
he Food and Drug Administration may adopt a new strategy that could prevent up to 40 percent of animalbased cancer tests. The FDA currently requires drug companies to test most new pharmaceuticals on two species of animals—rats and mice—for two years to see if the animals develop cancer. These tests can use between 1,000 and 1,500 animals per pharmaceutical. This year, scientists with the pharmaceutical industry trade group PhRMA presented a plan in which they would use information from prior studies, obviating the need for new tests. According to an analysis of past data, this method may prevent 40 percent of cancer tests. The FDA is reviewing the data and may modify their requirements later this year.
Presented at the Society of Toxicology annual meeting, March 2010.
EUropEan CHEmiCal aGEnCy
for companies that do not attempt to use available nonanimal strategies before conducting animal tests.
Summer 2010 GOOD MEDICINE Winter 2006
by Susan levin, m.S., r.d., and Kathryn Strong, m.S., r.d.
the latest in…
military Eyes Healthier School Food, Slimmer recruits
served in schools to address our nation’s childhood obesity crisis, which threatens the future strength of our military.
Christenson W, Taggart A, Messner-Zidell S. Too fat to fight: retired military leaders want junk food out of America’s schools. Washington, DC: Mission: Readiness;2010. Available at: http://missionreadiness.org./ MR%20National%20obesity%20Report.pdf. Accessed April 20, 2010.
What’s Contributing to obesity? meat, Cheese, Grease, ice Cream
TO EAT BETTER!
nhealthful foods served in school lunch lines could be undermining national security, according to a new report by senior retired military leaders who are pushing for smart investments in future generations. The report shows that three-fourths of young adults age 17 to 24 are unable to serve in the military, and excess weight is the most common medical reason. The report authors are calling on Congress to take immediate steps to improve foods and beverages
i WANT YOU
n increase in childhood obesity reflects increased intake of oils, meat, cheese, and frozen desserts, according to a new study by PCRM president Neal Barnard, M.D., in the American Journal of Clinical Nutrition. Dr. Barnard looked at food data maintained by the U.S. Department of Agriculture from 1909 to 2007. Meat intake rose from 123 pounds to more than 200 pounds per person per year with a greater than sixfold increase in chicken and turkey intake alone. In 2007, Americans also ate nine times more cheese and 16 times more frozen desserts than they did in 1909. Oil intake increased from 35 pounds to more than 86 pounds per person per year during
the same interval. Since 1970 (no prior data available), sweetener consumption doubled, mostly from carbonated beverages. Other long-term trends include decreased grain consumption, decreased fluid milk consumption, and increased fruit (mostly juices) and vegetable intake.
Barnard ND. Trends in food availability, 1909-2007. Am J Clin Nutr. 2010;91(suppl):1S-7S.
Erectile dysfunction linked to Heart disease
rectile dysfunction, or ED, is associated with increased risk of fatal heart attacks, according to a new study in the journal Circulation. Among 1,519 adult male research participants, those with ED had twice the risk of death from any cause, compared with those without ED. Men with ED were also 60 percent more likely to have a heart attack, stroke, or heart-related hospitalization or death. The new study confirms previous findings showing that both ED and heart disease are usually signs of atherosclerosis.
animal protein bad for bones
nimal protein is associated with decreased bone health, according to a recent study in the British Journal of Nutrition. In Beijing, 757 girls with an average age of 10 years were randomly assigned to a group consuming cow’s milk fortified with calcium, one consuming cow’s milk fortified with calcium and vitamin D, or a third group that served as controls and made no
Bohm M, Baumhakel M, Teo K, et al. Erectile dysfunction predicts cardiovascular events in high-risk patients receiving Telmisartan, Ramipril, or both. The oNgoing Telmisartan Alone and in combination with Ramipril Global Endpoint Trial/Telmisartan Randomized Assessment Study in ACE intolerant subjects with cardiovascular Disease (oNTARGET/TRANSCEND) Trials. Circulation. 2010;121:1439-1446.
changes. Bone mass was measured at the beginning of the study and at 12, 24, 48, and 60 months. While calcium intake was positively associated with bone health, animal protein, especially from meat and eggs, was negatively associated with bone mineral density and content.
Zhang Q, Ma G, Greenfield H, et al. The association between dietary protein intake and bone mass accretion in pubertal girls with low calcium intakes. Br J Nutr. 2010;103:714-723.
Winter 2010 Summer 2006 GOOD MEDICINE
Beyond Mice and M
PCRM Conference Explores Alternatives to Animal Research
is company created a surrogate human immune system that assesses human responses to potential vaccines and drugs. Her organization revolutionized breast cancer research by connecting women directly with clinical researchers. William L. Warren, Ph.D., and Susan Love, M.D., will join 20 other scientific experts speaking at PCRM’s upcoming conference on progress in reducing and replacing animal experimentation. Animal experimentation has long raised ethical objections, along with questions about its applicability to human health. These issues are debated often—but rarely studied and discussed in an organized forum.
PCRM’s “Animals, Research, and Alternatives: Measuring Progress 50 Years Later” conference will bring together global experts this August in Washington, D.C., to discuss the scientific and ethical imperatives associated with animal research. Reduce, Replace, Refine, Reevaluate An often-cited model for protecting animals in research, the “3 Rs,” was first described in the 1959 book The Principles of Humane Experimental Technique by W.M.S. Russell and R.L. Burch. The “3 Rs” ask researchers to reduce the number of animals used to the minimum necessary, refine or limit the pain and distress to which animals are exposed, and replace the use of animals with nonanimal alternatives when possible or use species deemed to be less capable of pain and distress. While the “3 Rs” were once viewed as a step forward, advancements in our understanding of animals and of scientific needs over the past five decades require a reevaluation of mandates regarding the use of animals in research. Fifty years after the “3 Rs” were first defined, PCRM will facilitate a reevaluation of this model. Alternatives Abound Scientists, physicians, and others will present scientific considerations related to animal research. They will cover the genetic and physiological differences between humans and various animal species, the economics of animal testing, and the modern approaches and testing methods that can replace the use of animals in research. Replacements for animal tests, which share the advantages of being human biology-based, include in vitro technologies, computer modeling, tissue engineering, epidemiological and clinical studies, genetic methods, and microdosing technologies. William L. Warren, Ph.D., the CEO and founder of VaxDesign Corporation, will discuss the benefits and applications of his company’s recently developed in vitro human immune system, which assesses new drugs and vaccines more accurately, compared with tests using animal methods.
August 26 and 27, 2010 Washington, D.C.
Find more information and register today at
Join experts from around the world fifty years after the development of the key model for the refinement, reduction, and replacement of animals in research. Medical professionals, scientists, ethicists, policymakers, and students are welcome.
A continuing medical education event
(Category 1, Maximum 16.5 credits)
P H y S I C I A N C o M M I T T E F o R R E S P o N S I B l M E D I C I N S E E E
GOOD MEDICINE Summer 2010
A Human Immune System in a Test Tube
he immune system is complex, adaptive, and remarkably effective. Its defense mechanisms are specific to an individual’s body and its tissues and cells. Research using animals has been limited in its ability to predict how the human body will react to pathogens and treatments. VaxDesign Corporation recently developed a model of the human immune system that can predict an individual’s immune response to a drug or vaccine candidate. MIMIC, or the Modular Immune In vitro Construct, is one of a growing number of alternatives to animal research. Because MIMIC is based on human immune cells, it shows human responses and can accurately predict undesirable responses. The system can also include a donor base of hundreds of individuals, accessing potential responses in diverse populations. The MIMIC System is designed to replace the use of animals for a range of research purposes, including vaccine
testing. For example, researchers have been working to develop an HIV/AIDS vaccine for decades. More than 85 vaccines have demonstrated positive outcomes in chimpanzees, but none have been effective in human trials. The research community has seen similar failures in using chimpanzees in research to develop a hepatitis C vaccine. The MIMIC System can process thousands of tests each month and is highly predictive. It could help accelerate the process of developing these and other vaccines—while producing data relevant to human populations. VaxDesign is already working with the International AIDS Vaccine Initiative, other nongovernmental organizations, the federal government, and leading pharmaceutical and biotechnology companies to improve their productivity and advance the effectiveness and efficiency of medical research.
Susan Love, M.D., of the Love/Avon Army of Women will explain how her organization has challenged breast cancer researchers to expand their focus to prevention research conducted on healthy women. The Army of Women has created a direct partnership between scientists conducting clinical trials and women who may qualify to participate in the trials. Robert J. Kavlock, Ph.D., will share the Environmental Protection Agency’s (EPA’s) perspective of the future of chemical testing. Dr. Kavlock is the director of the newly formed National Center for Computational Toxicology (NCCT) within the EPA’s Office of Research and Development. His talk will cover how nonanimal testing methods fit into the NCCT’s mission to improve risk identification in assessing environmental chemicals.
mentation. Distinguished researchers, veterinarians, and ethicists will speak about animals’ cognitive and affective capabilities and the effects of the pain and stress endured by animals used in research. Lori Marino, Ph.D., of Emory University will discuss noninvasive research on dolphin and whale cognition. Dr. Marino is the author of more than 80 publications, including the first definitive evidence of mirror self-recognition in bottlenose dolphins. Alicia Karas, D.V.M., an assistant professor at Tufts University, studies methods of pain assessment and treatment in mice, rabbits, and dogs. She will speak about the physiological effects of the pain and stress millions of mice endure in laboratories. Other speakers will cover nonhuman primate cognition, the emotional lives of animals, international The Impact on Animals frameworks for animal protection, mood and anxiety In addition to scientific considerations, speakers will disorders in chimpanzees, and other areas with ethical examine the ethical considerations of animal experi- implications for using animals in experiments.
Summer 2010 GOOD MEDICINE
be housed alone in steel cages for at least four years and subjected to daily restraint in primate chairs. NASA is funding the monkey radiation experiments in an attempt to shed light on the effects of deep space radiation on a human astronaut bound for Mars. But PCRM says the taxpayer money slated for the experiments would be better spent on humancentered methods, including human simulators equipped with sensors. “These experiments are both inhumane and scientifically unsound,” says John J. Pippin, M.D., F.A.C.C., PCRM’s senior medical and research adviser. “Blasting squirrel monkeys with radiation won’t help us understand how humans can survive the complex dangers of interplanetary travel.” On June 10, PCRM led a peaceful protest in front of McLean Hospital. The hospital was also presented with pledges from several primate sanctuaries willing to provide homes for the monkeys if McLean agrees to release them.
ONLINE > Ask Mclean Hospital president Scott Rauch, M.D., to cancel these experiments: PCRM.org/NASA.
PCRM Confronts NASA Monkey Experiments
elmont, we have a problem,” proclaimed PCRM’s billboards and train station ads near McLean Hospital in Belmont, Mass. The ads alerted Belmont commuters to NASA-funded monkey radiation experiments taking place at McLean. The $1.75 million experiments, proposed by McLean researcher Jack Bergman, Ph.D., involve exposing live squirrel monkeys to harmful radiation at Brookhaven National Laboratory on Long Island. The animals will then be shipped to McLean and compelled to perform tasks to test for cognitive impairment. The primates will
Facial Expressions of Mice in Pain
ice grimace in response to pain, just as humans do, according to a recent experiment that involved subjecting mice to harmful stimuli. Researchers found that, like humans, mice show pain with facial expressions that become more intense with greater levels of inflicted pain. To conduct this experiment, researchers at McGill University in Montreal, Canada, harmed mice using various stimuli, including dipping their tails in hot water and injecting them with acid. The researchers detected five signs of pain in the mice: they close their eyes tightly, their noses bulge, their cheeks bulge, they draw their ears apart, and they move their whiskers. The researchers claimed this experiment will lead to better treatment of mice in laboratories. PCRM experts say the experiments were both unnecessary and unethical, even though they demonstrated the painfulness of laboratory experiments. “Decades of research have provided indisputable evidence that rodents experience pain and fear—but the number of mice used in research is increasing, rather than decreasing,” says Hope Ferdowsian, M.D., M.P.H., PCRM’s director of research policy. “Our understanding of animal cognition and emotion is expanding quickly, but animal research protections have been slow to follow. It is time for scientists to change the ways in which research is conducted.” At PCRM’s upcoming Animals, Research, and Alternatives conference, global experts will discuss this issue and share ideas about how to move research ethics forward.
GOOD MEDICINE Summer 2010 GOOD MEDICINE Summer 2010
Doctor Files Complaint over Tulane’s Pig lab T
ulane University is one of America’s oldest medical schools, but it is one of the last in the nation to replace live animals in trauma training courses. This March, Louisiana physician and PCRM member Leslie Brown, M.D., filed a complaint with the U.S. Department of Agriculture alleging that Tulane is in violation of the Animal Welfare Act for using animals in trauma training. In Advanced Trauma Life Support (ATLS) training at Tulane, trainees cut into live, anesthetized pigs and practice emergency medical procedures. After the training session, the pigs are killed. “Using animals is not only cruel, it is a substandard way to teach emergency procedures that will be used on humans,” says John J. Pippin, M.D., F.A.C.C., PCRM senior medical and research adviser. “The school should immediately replace the use of animals with state-ofthe-art trauma training simulators that are already available in the Tulane simulation center.”
PCRM doctors lead a peaceful demonstration at Tulane.
Human-based simulators such as the TraumaMan System have been approved by the American College of Surgeons as a replacement for animal use in ATLS courses; 95 percent of medical facilities that teach ATLS courses have already switched to nonanimal teaching methods.
ONLINE > To ask Tulane’s dean to end the use of animals in the school’s ATlS program, visit PCRM.org.
New Society Promotes Nonanimal Chemical Testing
In Vitro Sciences Inc. have formed a new scientific society to promote nonanimal toxicological testing methods. This is the first scientific society in North America devoted to such a mission. Through regular meetings and activities, the American Society for Cellular and Computational Toxicology will facilitate the development, acceptance, and routine use of cellular and computational toxicology methods by open dialogue among industry, academic, advocacy, and regulatory scientists. The society will strive to include the participation of young scientists. The Institute for In Vitro Sciences Inc. and PCRM were inspired to create the society by the surge of interest in toxicology since the publication of Toxicity Testing in the 21st Century: A Vision and a Strategy, a 2007 National Academy of Sciences report calling for a new toxicity testing strategy based on human cells and tissues instead of animals.
Cellular and Computational Toxicology’s new website: ASCCTox.org.
CRM and the Institute for
Contact the FDA About Animal Testing
very day, thousands of animals are experimented on and killed to create and test drugs, many of which will never help a sick human being. That’s why PCRM and an international coalition of scientists, doctors, and animal-protection organizations filed the Mandatory Alternatives Petition with the u.S. Food and Drug Administration. The petition asks the FDA to mandate the use of validated nonanimal testing methods, when those alternatives exist, to create safer drugs for American consumers. The FDA is currently reviewing the initiative. During this time, we need you to contact the FDA and urge the agency to mandate the use of validated alternatives to animal tests. Please write to: Margaret A. Hamburg, M.D., Commissioner u.S. Food and Drug Administration 5600 Fishers lane Rockville, MD 20857 ONLINE > To learn more about the Mandatory Alternatives Petition, visit Alternatives-Petition.org. To sign PCRM’s online petition to the FDA, go to Support.PCRM.org/FDA_Petition.
ONLINE > Check out the American Society for
Summer 2010 GOOD MEDICINE
PCRM in East Africa P
May 10, 2010
CRM’s Hope Ferdowsian, M.D., M.P.H., and Debra Durham, Ph.D., recently traveled to East Africa to collect data for a study on mental health in chimpanzees previously used in laboratories. This is Dr. Ferdowsian’s journal entry at the end of the trip: We’ve just reached the end of our journey in East Africa, and it has been a phenomenal trip. We’ve collected data on more than 300 chimpanzees in the wild and in African sanctuaries. This data will be the basis for comparison with chimpanzees previously used in research and currently in sanctuaries in the United States, Japan, and the Netherlands, for our study on mental illness in traumatized chimpanzees. We haven’t been afraid to get our hands (and feet) dirty while here. Deb helped with chimpanzee care when she wasn’t collecting data, and I worked with a response team to help resolve a medical outbreak. While Deb finished the week by wrapping up data collection for our chimpanzee study, I concluded a week of media interviews and presentations at the University of Nairobi campuses for the College of Veterinary Medicine and the Colleges of Medicine, Pharmacy, and Dentistry. At the university,
I talked with enthusiastic students and faculty members about alternatives to the use of animals in education and Hope Ferdowsian, M.D., M.P.H., (left) research. Earlier presents a completion certificate for nursing Continuing Medical Education. this week, I had a 45-minute live interview with a popular Kenyan TV host about the benefits of vegetarian diets. The switchboard lit up with calls that spilled into the next show. Unfortunately, Africa is no exception to the growing number of areas affected by chronic diseases like heart disease, diabetes, and cancer. At the request of our Ugandan study partners, Deb and I worked with our research assistant to set up a continuing education program for nurses in rural villages. I spoke for hours about the importance of nutrition and then answered questions on everything from medical management of HIV to peptic ulcer disease. Local residents prepared a healthful and abundant vegan meal that included plantains, beans, greens, cassava, and other locally grown fruits, vegetables, and grains. Our message was welcome, and we received invitations to return and expand our work in this area. We’re looking forward to our return to the United States, but we’re also looking forward to a return trip to Kenya in September for a pan-Africa conference on animal welfare.
CHIMPANZEE SANCTuARy & WIlDlIFE CoNSERVATIoN TRuST
prevention & nutrition PCRM’s New Doctor’s office outreach Program
o, you’re sitting in your underwear, waiting for the doctor to come into the exam room. The minutes are slowly ticking by, and you’ve already read the dog-eared copy of People and all the fine print on the diplomas on the wall. Wouldn’t this be a perfect time to actually get some information about health? We thought so, too. PCRM has launched a new ONLINE > Doctors: order your free Doctor’s Office Outreach package of materials at PCRM.org/ program to provide physician DoctorOutreach. members with the tools they need for educating patients about nutrition’s role in maintaining good health. With a stack of Vegetarian
GOOD MEDICINE Summer 2010
Starter Kits at the registration desk and colorful, eyecatching posters in every exam room, PCRM doctors are ready to spread a lifesaving message.
prevention & nutrition
Get Healthy, Go Vegan with Dr. Barnard’s New Cookbooks
wo new PCRM cookbooks encourage everyone from beginners to expert chefs to prepare more plant-based meals. From quick and delicious FireRoasted Tomato Black Bean Chili to exotic Chilled Canary Melon and Green Zebra Tomato Soup with Tofu Cardamom Cream, recipes in The Get Healthy, Go Vegan Cookbook and The Best in the World III: Healthful Recipes from Exclusive and Out-of-the-way Restaurants demonstrate that a vegan diet is easy and delicious. “For most people, starting a vegan diet is an eyeopening experience,” says PCRM president Neal Barnard, M.D. “They start to lose unwanted pounds, their energy improves, and their digestion gets better. If they have diabetes, high cholesterol, or high blood pressure, these problems begin to improve, too. Headaches and joint pains start to melt away.”
In The Get Healthy, Go Vegan Cookbook, Dr. Barnard and nutritionist Robyn Webb offer meals that use familiar ingredients, require minimal effort, are free of animal products, are low in fat, and have a low-to-moderate glycemic index. The Best in the World III, edited by Dr. Barnard, features delicious and unique recipes from restaurants across the globe. Join monks in a temple courtyard in the Far East, passengers on a French luxury yacht, or even a rock star in Akron, Ohio, for an unforgettable culinary adventure. Often exotic and always flavorful, these plantbased recipes are designed to TO ORDER > See PCRM Marketplace be within the abilities of any on page 21 or visit PCRM.org/shop. amateur chef.
Double Down or Double Bypass?
FC’s new Double Down sandwich consists of high-fat bacon and high-fat cheese sandwiched between two pieces of high-fat fried chicken. In April, PCRM dietitians urged KFC not to advertise the Double Down to children and to post a warning about the health risks associated with the high-fat sandwich. In a letter to David C. Novak, chairman of Yum! Brands Inc., the company that owns KFC, Susan Levin, M.S., R.D., the director of nutrition education for PCRM, calls the sandwich a “symbol of corporate irresponsibility” at a time when America
is grappling with record childhood obesity numbers. “The Double Down has death wish appeal,” Levin says. “The Double Down combo meal has more than half the maximum amount of fat and calories that most adults should consume in an entire day—and approaches the maximum recommended amount of sodium for a whole day. Children shouldn’t be exposed to advertisements for this absurd product.” ONLINE > Take action! Join PCRM The “Original Recipe” in urging KFC to keep the Double version of the Double Down Down out of children’s hands: stacks up at 540 calories, 32 PCRM.org/DoubleDown. grams of fat, and 1,380 milligrams of sodium. The Double Down Combo Meal contains 1,000 calories, 45 grams of fat, and 2,120 milligrams of sodium. network—including a Facebook fan page and a discussion board featuring registered dietitians—to help participants make sustainable dietary changes. If you are already following a vegan diet, this program can help you cut down on oils and other fats and add more healthful meals to your menu.
ONLINE > Sign up for the Sept. 6 Kickstart: 21DayKickstart.org. 11
Kickstart Your Diet
CRM’s 21-Day Vegan Kickstart program has already given more than 65,000 people the chance to try a healthful vegan diet. Now, Hollywood celebrities, star athletes, chefs, and nutrition experts are teaming up again to launch a Kickstart that will begin Sept. 6. Kickstarters receive daily e-mails for a step-bystep diet makeover, including recipes and nutrition webcasts. The Kickstart offers an interactive support
Summer 2010 GOOD MEDICINE
prevention & nutrition
The Anti-Arthritis Diet B
A New Pillow, or a New Diet?
roadway dancer, singer, and actress Donna McKechnie was at the height of her career, starring in the hit musical A Chorus Line. In 1976, she earned the Tony Award for Best Actress in a Musical.
Dana Armstrong, R.D., C.D.E.
ana Armstrong, a registered dietitian in Monterey, Calif., started having neck pain in 2007. At first, she thought she might need a new pillow. Then her whole body started to hurt, and she wondered if it was a result of stress from working long hours. “Exercise soon became painful,” says Armstrong. “My hands even started hurting when I was on the elliptical.” She had a physical a week before a family vacation and lab results showed she had rheumatoid arthritis. After her family’s drive to Phoenix, she could not even get out of bed. She was only 49
Four years later, she was diagnosed with rheumatoid arthritis. She was told that she would never again dance—or even walk. It appeared to be the end of her career. She was determined to recover. A year later, with the help of diet and lifestyle changes, she rebounded and was performing again. She credited a healthful years old. But facts were facts, and her diet free of dairy products, red meat, symptoms were not going away. She caffeine, and other arthritis triggers. started taking prednisone—a steroid. For years, people have suspected that She then started on methotrexate and diet plays a role in arthritis. Many have plaquenil. But it was not enough and noticed improvements when they avoid soon she had to stop working. dairy products or certain other foods. “I started spending all my time Initially, the evidence was anecdotal. researching arthritis,” says Armstrong. But an increasing volume of research “There was very little information shows that dietary changes do help. A about food and arthritis, but I soon 2002 study looked at the influence of a came across Dr. Barnard’s book Foods very low-fat vegan diet on moderate to that Fight Pain and other research on severe rheumatoid arthritis. After people foods that are inflammatory.” with arthritis followed a vegan diet for After reading Dr. Barnard’s book four weeks, almost all their symptoms and The China Study by T. Colin decreased significantly. Another study Campbell, Ph.D., she went completely found that a gluten-free vegan diet imvegan. Her symptoms started to proved the signs of arthritis. A raw vegan disappear. She then went to Dr. John diet was shown to decrease joint stiffness McDougall’s 10-Day live-In Program, and pain in another study. and he suggested she stop taking her Vegan diets omit dairy products, meat, medications and supplements. She and eggs, all of which are common trigdid. After a few months on her new gers for joint pain. They also dramatically diet, not only did she recover from reduce intake of fat, especially saturated arthritis, she also lost 40 pounds and fat. This can affect the immune processes experienced other health benefits, that influence arthritis. Vegetables are including eliminating her cystic acne. also rich in antioxidants, which can neu“I also sleep very well now,” says tralize free radicals. Free radicals attack Armstrong. “Apparently I didn’t need a many parts of the body and intensify new pillow!” aging processes, including those of the joints.
PCRM Helps Improve D.C. School Nutrition
he Council of the District of Columbia has passed what may be the strongest measure passed by any jurisdiction in the battle against childhood obesity. In May, the council passed the D.C. Healthy Schools Act, raising nutritional standards, bringing affordable, healthy food to low-income neighborhoods, encourag12
GOOD MEDICINE Summer 2010
ing vegetarian options, and increasing health education and physical activity. The council felt it had no choice. Nearly half the city’s children are overweight or obese. PCRM dietitian Kathryn Strong, M.S., R.D., worked with D.C. council members on the nutrition aspects of this bill.
pCrm legislative Fund
Advancing the PCRM Mission
CRM’s legislative work has grown in recent years, and we created the PCRM Legislative Fund last December to be a voice for change on Capitol Hill and in state legislatures. As a 501(c)(4) nonprofit organization, the PCRM Legislative Fund helps shape important public policy reforms in the areas of ethics and health. To support the legislative fund, simply send a contribution using the envelope enclosed in this issue or make a secure gift online at PCRMLF.org.
ONLINE > To stay informed about our legislative campaigns, sign up online to be a part of our rapidly growing legislative Action Network.
Pamela Anderson Supports Great Ape Protection Act
ctress Pamela Anderson recently joined the PCRM Legislative Fund in urging Congress to support the Great Ape Protection Act. The act would ban invasive chimpanzee experiments and support human-based research methods. In a letter to lawmakers, Anderson zeroed in on chimpanzee experiments on hepatitis C. “As one of more than 3 million Americans living with hepatitis C,” she wrote, “I am writing to ask that you take steps to end ineffective and cruel research using chimpanzees and direct federal funds to modern, human-based research methods that will be more effective at finding a vaccine and treatment for hepatitis C and other deadly diseases.” Decades of experiments in chimpanzees have not yielded a human vaccine against hepatitis C. The hepatitis C virus behaves very differently in humans and chimpanzees. Chimpanzees are rarely chronically infected by hepatitis C, and maternal-fetal transmission is much less likely than in humans. Currently, leading hepatitis C researchers are using cell-based research methods instead of animals. Chimpanzee research has also failed HIV, malaria, cancer, and neurological research. The Great Ape Protection Act, which has nearly 150 congressional co-sponsors, would end invasive experiments on chimpanzees, release the 500 federally owned chimpanzees to sanctuaries, and prohibit the future breeding of chimpanzees for research. Based on observational pilot data, PCRM primatologist Debra Durham, Ph.D., and PCRM director of research policy Hope Ferdowsian, M.D., M.P.H., have found that chimpanzees once forced to live in laboratory settings can display symptoms similar to those seen in humans suffering from depression, post-traumatic stress disorder, and other anxiety disorders.
ONLINE > To join Pamela Anderson in urging Congress to pass the Great Ape Protection Act, visit PCRMLF.org/GAPA.
Summer 2010 GOOD MEDICINE
pCrm legislative Fund
Pushing for Better Test Methods
he PCRM Legislative Fund is working hard to ensure that new chemical regulations protect humans and the environment while reducing animal testing. Currently, the Environmental Protection Agency regulates industrial chemicals through a 34-yearold statute called the Toxic Substances Control Act (TSCA). A bill introduced in the U.S. Senate in April, the Safe Chemicals Act of 2010, and a bill to be introduced in the House of Representatives this summer aim to update TSCA. However, the new bills could lead to increased use of animals for chemical testing. PCRM scientist Nancy Beck, Ph.D., is pushing for provisions that would better protect both humans and animals in the House Nancy Beck, Ph.D. of Representatives’ stakeholder meetings, and
ONLINE > Please help ensure that this legislation becomes a launch pad for better methods—techniques that rely on modern cell-based tests instead of animals. Get involved: PCRMLF.org/tox.
has outlined principles necessary for replacing animal use in written comments to the House Energy and Commerce Committee. “Animal-based tests have been used for decades, but they are obviously cruel and don’t provide the most accurate information,” says Dr. Beck. “They’re also extremely inefficient. In fact, there are so many chemicals to test that it would take decades to test them all using animal methods.” The PCRM Legislative Fund is encouraging Congress to fund the development of cell, tissue, and computer-based methods that can provide information on chemicals more quickly than animal-based tests. We are also urging Congress to require the use of available nonanimal methods to reduce animal use and drive innovation in test method development. These and other PCRM Legislative Fund recommendations for efficient, relevant testing will help accomplish the primary goal of the bills—more effective regulation of potentially toxic chemicals.
BEST Practices Act Gains New Supporters
hen the military teaches personnel about emergency medical procedures, it uses a highly controversial teaching method. The courses involve subjecting thousands of animals to stab wounds, burns, and other injuries. The PCRM Legislative Fund is promoting a bill that would improve military medical training by replacing these kinds of animal laboratories. The Battlefield Excellence through Superior Training (BEST) Practices Act, H.R. 4269, would end the Department of Defense’s use of live pigs, goats, and monkeys in combat trauma and chemical casualty care courses. The BEST Practices Act would require the military to transition to ethical and educationally superior human-based methods, including medical simulators, which are widely used in civilian medical centers to teach trauma management. H.R. 4269 has two new co-sponsors—Rep. Lucille Roybal-Allard, D-Calif., and Rep. Grace Napolitano, D-Calif.
ONLINE > Ask your representative to co-sponsor H.R. 4269, the BEST Practices Act, to help animals and our troops: PCRMLF.org/DOD.
GOOD MEDICINE Summer 2010
pCrm legislative Fund
Athletes, Celebrities Ask Congress for Healthier School Meals
Olympic sprinter Allyson Felix, House Majority Whip James E. Clyburn (D-S.C.), and NBA star John Salley
he campaign to give students healthier choices in the lunch line is in full swing. PCRM experts, along with scores of celebrities, professional athletes, health care professionals, and students, are calling on Members of Congress to support H.R. 4870, the Healthy School Meals Act of 2010. Rep. Jared Polis, D-Colo., introduced the Healthy School Meals Act in March. The bill aims to reverse the epidemic of childhood obesity by helping school food service programs offer more fruits, vegetables, and healthful plant-based meal options and nondairy beverages. The bill already has more than 60 co-sponsors in the House of Representatives and is the second most supported school nutrition bill in Congress. Three gold-medal-winning Olympians—swimmer Amanda Beard, soccer goalkeeper Hope Solo, and gymnast Nastia Liukin—wrote to lawmakers in early April urging them to support this bill. They explained that healthful food is extremely important to children’s health and development—whether they hope to be professional athletes or not. The momentum continued on April 21 when nearly 1,000 concerned physicians, parents, students, and citizens signed up to call their representatives on National School Lunch Call-In Day. The evening before the call-in day, Elizabeth Kucinich, PCRM’s director of public affairs, actress Deidre Hall, and local student activist Nina Gonzalez—who helped her school system add vegetarian options—hosted a conference call to answer questions about the Healthy School Meals Act. More recently, NBA star John Salley and Olympic gold-medal-winning sprinter Allyson Felix showed their support for the bill in the halls of Congress. At a May 5 congressional breakfast co-hosted by PCRM, in cooperation with the Congressional Black Caucus and the Congressional Families for Children’s Health, Salley and Felix participated in a roundtable discussion about
improving the nutritional quality of foods served in our nation’s lunchrooms. Salley and Felix were joined by PCRM president Neal Barnard, M.D., Kucinich, and nutrition advocate Wyntergrace Williams—daughter of talk show host Montel Williams. Members of Congress joining the conversation included representatives Maxine Waters, D-Calif., Donna M. Christensen, D-Virgin Islands, Edolphus Towns, D-N.Y., Dennis Kucinich, D-Ohio, and Polis. The breakfast featured an array of gourmet plant-based ONLINE > Ask your representative dishes catered by celebrity chef to join the growing list of Healthy Lauren Von Der Pool. School Meals Act supporters. Take The Healthy School Meals action at PCRMLF.org. Act would help schools offer Join the campaign on students healthy, plant-based Facebook: Facebook.com/ meals, which are generally PCRMSchoolLunchRevolution. lower in fat and saturated fat and higher in fiber than traditional school meals. With the percentage of overweight and obese children now at or above 30 percent in 30 states, these healthier meals could make a major impact on children’s health.
Healthy School Meals Act
Johansson, richie/GEtty imaGES
etters in support of the Healthy School Meals Act are stacking up on Rep. George Miller’s desk. But a few letters may be tacked up on his bulletin board. Rep. Miller, D-Calif., chair of the committee that child nutrition legislation is passing through, has received letters from Scarlett Johansson, Ellen DeGeneres, Portia de Rossi, Nicole Richie, and many other celebrities in support of healthy school meal choices. Media outlets across the country have covered the bill’s celebrity support. An article in the Capitol Hill publication Roll Call began, “Celebrities get a lot of mail—but Rep. George Miller might just get the most mail from celebrities.” In their letters, they ask Miller to help fight childhood obesity and related chronic diseases by including language from the Healthy School Meals Act in updated child nutrition legislation.
Portia de Rossi
Summer 2010 GOOD MEDICINE
the Cancer project
the Cancer project Update
Another Successful Run for The Cancer Project
Food for Life Classes Now in U.K.
t’s official—the Food for Life program has reached the United Kingdom! Classes are now up and running in both Stafford and Wolverhampton, spreading the important message of good nutrition for cancer prevention and survival. Sue Brown from Valencia, Spain, attended the inaugural U.K. series in March and said, “I found the class very interesting, clear, and educational. The food was great and I was most surprised by foods that I always believed were good for us were actually harmful to our health. I am looking forward to attending more classes in the future.” The leader behind The Cancer Project’s U.K. expansion is Ayo Olaseinde. We appreciate the support of Saladmaster in bringing these classes to fruition.
yle Hall ran in the Boston Marathon this spring to raise money for The Cancer Project. Kyle, an athlete whose plant-based diet helped him recover from a 2002 cancer diagnosis, completed the race in record time—and his efforts raised over $2,100 for our educational programs. Here’s an excerpt of what Kyle wrote to us after the race: “I had a strong, gutsy race. I thought a lot about The Cancer Project donors and
those who could not be out running for various health reasons. This really helped me keep up the pace … I was happy with how I performed on the finishing stretch and with my overall time. And it was all vegan powered!”
Five Foods to Avoid at Mexican Restaurants
report by The Cancer Project will make Mexican food enthusiasts think twice about what they are choosing. While Mexican restaurants offer many healthful choices, from bean burritos to veggie fajitas, there are also some items you’ll want to skip. With more than 2,100 calories and more fat and sodium than most people should eat in a day, the Charbroiled Steak Nachos at Baja Fresh tops a list of five foods to avoid. Here are the five worst entrées:
Rank Worst 2nd worst 3rd worst Worst Mexican Items Charbroiled Steak Nachos Grilled Fajita Salad Crispy Honey-Chipotle Chicken Crispers Pulled Pork Burrito Ground Beef Burrito Restaurant Baja Fresh Mexican Grill Chevys Fresh Mex Chili’s Qdoba Mexican Grill Moe’s Southwest Grill
ONLINE > See the latest class offerings: CancerProject.org/Classes.
4th worst 5th worst
Golf for Your Health and a Good Cause
he first Masters in April Golf Tournament, held in Dallas, encouraged
people to golf for their health and the health of loved ones. The event, organized
by Rob Weseman of Lone Star Health Systems Inc., raised more than $2,800 for The Cancer Project to help our efforts in continuing to inform the public about good nutrition through the Food for Life program. Rob is already looking ahead to host the same event in 2011. The Cancer Project is so grateful for Rob’s support. His efforts have made it possible to continue to provide people with resources they need for cancer prevention and survival.
GOOD MEDICINE Summer 2010 GOOD MEDICINE Summer 2010
the news you need
the Cancer project
By Joseph Gonzales, R.D., and Susan Levin, M.S., R.D.
vegetables improve Survival from ovarian Cancer
omen diagnosed with ovarian cancer are more likely to survive if their diets include plenty of fruits and vegetables, according to a new study in the Journal of the American Dietetic Association. Researchers examined food patterns prior to ovarian cancer diagnosis in 341 Illinois women. They found that yellow and cruciferous vegetables, in particular, contributed to longer survival, whereas consumption of dairy products and red and processed meats shortened lifespan. The authors concluded that low-fat, plant-based diets are not only beneficial for cancer prevention—they may also play a role in increasing survival time after diagnosis. Ovarian cancer is the fifth leading cause of cancerrelated death among women in the United States.
meat-based diets increase bladder Cancer risk
eat consumption increases the risk of bladder cancer, according to a new study presented at the American Association for Cancer Research’s annual meeting. Researchers studied the diets of 884 participants with bladder cancer and 878 healthy people. Study findings suggest that those who eat the most meat are up to 58 percent more likely to develop bladder cancer. Eating well-done meat was linked to an almost twofold increased risk of bladder cancer. Cooking meat at high temperatures produces carcinogens called heterocyclic amines. Study participants who consumed the most bacon, pork chops, fried chicken, and fried fish also had a higher risk.
Dolecek TA, McCarthy BJ, Joslin CE, et al. Prediagnosis food patterns are associated with length of survival from epithelial ovarian cancer. J Am Diet Assoc. 2010;110:369-382.
lin J, Wang JM, Grossman BH, et al. Red meat and heterocyclic amine intake, metabolic pathway genes, and bladder cancer risk. Report presented at: American Association for Cancer Research 101st Annual Meeting; April 17, 2010: Washington, DC.
vegetables, Fruits, Soy Help prevent breast Cancer
oy products, fruits, and vegetables reduce the risk of developing breast cancer, according to a new study in the American Journal of Clinical Nutrition. Postmenopausal women who consumed plenty of soy products, fruits, and vegetables had a 30 percent lower risk of developing breast cancer, compared with those who consumed relatively little of these foods. The research was based on about 34,000 women in the Singapore Chinese Health Study. The longer the women had consumed these healthful foods, the less chance they had of developing breast cancer.
Butler lM, Wu AH, Wang R, Koh WP, yuan JM, yu MC. A vegetable-fruit-soy dietary pattern protects against breast cancer among postmenopausal Singapore Chinese women. Am J Clin Nutr. Published ahead of print February 24, 2010. doi: 10.3945/ajcn.2009.28572.
The Cancer Project is a nonprofit PCRM subsidiary that advances cancer prevention and survival through nutrition education and research.
GOOD MEDICINE Winter 2010
Summer 2010 GOOD MEDICINE
PCRM’s Art of Compassion Gala Celebration!
CRM’s gala event on April 10 in Hollywood marked an important milestone—25 years of advancing compassion in medicine and science. Guests came from near and far to be a part of this special occasion, which allowed us to shine the spotlight on what we have accomplished with hard work and perseverance and also highlight the challenges in research and health that still need to be tackled to save human and animal lives. The weekend of activities began on Friday night with a reception, followed on Saturday by a daylong, standingroom-only nutrition conference presented by leading scientific experts, and culminated on Sunday with a president’s circle brunch. During Saturday night’s main event, guests dined on heavenly vegan cuisine created by Tal Ronnen, cheered on performers and award winners, and danced the night away at the after party. During the program, we premiered our new video PCRM: Opening the Doors to Compassion. To watch this compelling short film, please visit PCRM.org/about/ opening_doors_to_compasssion.html. At PCRM.org/Gala2010, view a fiveminute highlight video of the event and an album of spectacular gala photos.
Sublime owner Nanci Alexander
Steering Committee chair James Costa with singer Leona Lewis
John Salley and Maggie Q take the stage to kick off the program
Event chairs Kathy and Tom Freston
PCRM president Neal Barnard, M.D.
david miCHaEl pHotoGrapHy
Event host Cindy Landon with son Sean and daughter Jennifer
Auction chair Bobi Leonard
Committee member Rod Summers
Committee member Lorrie Attalla
Congressman Dennis Kucinich and wife PCRM director of public and government affairs Elizabeth Kucinich
GOOD MEDICINE Summer 2010 GOOD MEDICINE Summer 2010
The Voice of Compassion Award
PCRM’s newest award honors those who, by word and example, have communicated caring, compassion, and the highest ethical principles. The 2010 honorees are Ellen DeGeneres, Portia de Rossi, Marilu Henner, and Alicia Silverstone.
Neal Barnard, M.D., presents Ellen with the Voice of Compassion Award Marilu Henner takes the stage to accept her award
The benjamin Spock Award for Compassion in Medicine
Baxter D. Montgomery, M.D., F.A.C.C., Houston Cardiac Association and HCA Wellness Center
Dr. Montgomery on the red carpet
Art of Compassion Award
Robert l. “Skip” Trimble
Skip Trimble addresses gala guests
The Henry Heimlich Award for Innovative Medicine
Gilman Veith, Ph.D., International QSAR Foundation
david miCHaEl pHotoGrapHy
Dr. Veith receives the award from Henry Heimlich, M.D.
ONLINE > To learn more about the 2010 awardees and their accomplishments, please visit PCRM.org/Gala2010.
Summer 2010 GOOD MEDICINE
The Best in the World Fast, Healthful Recipes from Exclusive and Out-ofthe-Way Restaurants Neal D. Barnard, M.D., Editor This popular collection of wonderfully healthy recipes comes from the world’s best and most unusual restaurants. Enjoy these vegan delicacies at home. Hardcover, 71 pgs, $11.95 The Best in the World II Healthful Recipes from Exclusive and Out-of-the-Way Restaurants Jennifer L. Keller, R.D., Editor Travel around the world to discover treasures from side-street cafes and elegant hotel dining rooms. Attractively illustrated, this delightful vegan cookbook is the sequel to PCRM’s original international recipe collection. Hardcover, 71 pgs, $11.95 The Best in the World III NEW! Healthful Recipes from Exclusive and Out-of-the-Way Restaurants Neal Barnard, M.D., Editor Discover delicious and unique recipes from restaurants across the globe. Join monks in a temple courtyard in the Far East, passengers on a French luxury yacht, or even a rock star in Akron, Ohio, for an unforgettable culinary adventure. Often exotic and always flavorful, these plant-based recipes are designed to be within the abilities of any amateur chef. Hardcover, 71 pgs, $11.95 Macro for the Mainstream DVD Sheri DeMaris TV host Sheri DeMaris believes “your kitchen is your medicine cabinet.” In this exciting DVD, she prepares easy-to-follow macrobiotic recipes using whole, organic foods and offers simple suggestions for improving one’s health and the health of our planet. $24.95 Speed Vegan Quick, Easy Recipes with a Gourmet Twist Alan Roettinger Chef Roettinger’s fun and creative cooking style results in meals that stand out from the ordinary. Includes recommendations for basic kitchen staples and ways to save money on essential kitchen equipment. All dishes can be completed in 30 minutes or less. 192 pgs, $19.95
NEW! Thrive Fitness The Vegan-Based Training Program for Maximum Strength, Health, and Fitness Brendan Brazier Professional Ironman triathlete Brendan Brazier presents his own easy-to-apply system of total health and fitness. Learn how to get maximum results in minimum time, sharpen mental clarity, increase energy, and prevent injuries. Includes 6-week workout plan and list of 15 top foods to fuel workouts, as well as 30 vegan recipes. 272 pgs, $15.95
ReSeaRCh ISSUeS What Will We Do If We Don’t Experiment on Animals? Medical Research for the 21st Century C. Ray Greek, M.D., and Jean Swingle Greek, D.V.M. The Greeks answer the title’s question with a tour of truly modern medical research. With advances in the study of human genetics and the ability to measure human responses to drugs at the molecular level, researchers will find it increasingly difficult to justify the crude data accumulated from animal experimentation. 262 pgs, $24.99 Second Nature The Inner Lives of Animals Jonathan Balcombe, Ph.D. Do baboons have a keen sense of right and wrong? Do chickens find certain human faces attractive in the same way people do? Balcombe paints a new picture of the inner lives of animals that diverges from the struggle-or-perish image often presented in the popular media. He challenges traditional views of animals and spells out why the human-animal relationship needs a complete overhaul. 256 pgs, $27.00 heaLTh aNd NUTRITIoN NEW EDITIoN FRoM PCRM Nutrition Guide for Clinicians, second edition Physicians Committee for Responsible Medicine This comprehensive medical reference manual covers nearly 100 diseases and conditions, including risk factors, diagnoses, and typical treatments. Most importantly, it provides the latest evidence-based information on nutrition’s role in prevention and treatment. Includes an in-depth examination of general nutrition, macronutrients, micronutrients, and nutritional requirements for all stages of life. 745 pgs, $19.95 Special Discount $17.95 Quantum Wellness A Practical and Spiritual Guide to Health and Happiness Kathy Freston Learn how to make the small steps that can significantly improve the health of mind, body, and spirit. In addition to promoting wholeness in work and relationships, Freston explains the advantages of a plant-based diet from health, ethical, and environmental perspectives. Includes 45 vegetarian recipes, two weeks of meal plans, and a general shopping list. 288 pgs, $14.95 20
GOOD MEDICINE Summer 2010
Skinny Bitch A No-Nonsense, Tough Love Guide for Savvy Girls Who Want to Stop Eating Crap and Start Looking Fabulous! Rory Freedman and Kim Barnouin This bestselling vegan guide pulls no punches. Entertaining and sassy, the book rests on a solid health and nutrition foundation. “Many priceless-yet-unprintable dictums certainly make you laugh in a way few diet books can.” –iVillage 224 pgs, $13.95 Skinny Bitch in the Kitch Kick-Ass Recipes for Hungry Girls Who Want to Stop Cooking Crap (and Start Looking Hot!) Here’s the companion cookbook to the outrageous bestseller Skinny Bitch. 75 easy, satisfying recipes, served up with an irreverent sense of fun. “A hilariously bawdy vegan cookbook for the modern Mrs. Cleaver.” –Domino 192 pgs, $14.95 How to Eat Like a Vegetarian Even If You Never Want to Be One Carol J. Adams and Patti Breitman Out of time and out of ideas? Cook fast, cook healthy with more than 250 shortcuts, strategies, and simple solutions. More than a cookbook—though it abounds with recipes—this guide will get you started on a healthier path with a few flips of the page. 214 pgs, $20.00
NEW! The Spectrum A Scientifically Proven Program to Feel Better, Live Longer, Lose Weight, and Gain Health Dean Ornish, M.D. Whether you want to lose weight, lower your cholesterol, reverse a major disease, or find a sustainable, joyful way of life, this book can make a powerful difference. Dr. Ornish’s latest research shows how changing your lifestyle changes your genes, turning on disease-preventing genes while turning off diseasepromoting genes—even affecting parts of chromosomes that control lifespan. Includes 100 recipes. 416 pgs, $17.00
From Neal D. Barnard, M.D., PCRM president
The Get Healthy, Go Vegan Cookbook 125 Easy and Delicious Recipes to Jump-Start Weight Loss and Help You Feel Great These recipes are based on Dr. Neal Barnard’s landmark two-year study, which shows that a vegan diet effectively controls type 2 diabetes. In fact, it’s also beneficial for weight loss, the reversal of heart disease, and the improvement of many other conditions.Dr. Barnard and nutritionist Robyn Webb offer easy, delicious meals to improve your health. 248 pgs, $18.95 A New Approach to Nutrition for Diabetes DVD Neal D. Barnard, M.D. Turn back the clock on diabetes through a low-fat vegan diet. In eight compelling lessons, Dr. Barnard explains his groundbreaking research, funded by the National Institutes of Health, and how to put it to work in your life. Includes cooking demonstrations by chef Toni Fiore and a grocery store tour by Susan Levin, R.D., and Caroline Trapp, M.S.N., C.D.E. 192 mins, $19.95 Dr. Neal Barnard’s Program for Reversing Diabetes I f you have diabetes or are concerned about developing it, this program could change the course of your life. Dr. Barnard’s groundbreaking clinical studies, the latest funded by the National Institutes of Health, show that diabetes responds dramatically to a low-fat, vegetarian diet. Rather than just compensating for malfunctioning insulin like other treatment plans, Dr.Barnard’s program helps repair how the body uses insulin. Includes 50 delicious recipes. 288 pgs, $15.95 Foods That Fight Pain Did you know that ginger can prevent migraines and that coffee sometimes cures them? Drawing on new research, Dr.Barnard shows readers how to soothe everyday ailments and cure chronic pain with common foods. 348 pgs, $14.95 The Love-Powered Diet Eating for Freedom, Health, and Joy Victoria Moran Drawing on her personal experience, Moran applies Twelve Step principles to find freedom from compulsive eating and yo-yo dieting. She proposes a peaceful, natural way of eating that keeps weight off without dieting. 241 pgs, $20.00
The Sublime Restaurant Cookbook South Florida’s Ultimate Destination for Vegan Cuisine Nanci Alexander The flavors and beauty of south Florida’s award-winning Sublime Restaurant are compiled here with some of Sublime’s most famed culinary creations. From Asian, Latin, or Mediterranean influences to more typical American fare, each recipe is delightfully conceived, beautifully presented, and yet surprisingly quick to prepare. 117 pgs, $19.95
Breaking the Food Seduction We all have foods we can’t resist, foods that sabotage our health. But banishing those cravings for chocolate, cookies, cheese, or burgers isn’t a question of willpower, it’s a matter of biochemistry. Drawing on his own research and that of other leading institutions, Dr. Barnard reveals how diet and lifestyle changes can break the craving cycle. 324 pgs, $16.99 Turn Off the Fat Genes Genes, including those that shape our bodies, actually adapt to outside influences. Dr. Barnard explains the process and provides a three-week gene-control program complete with menus and recipes by Jennifer Raymond. Here are powerful tools for achieving long-term weight loss and better health. Paperback, 350 pgs, $14.95 A Physician’s Slimming Guide for Permanent Weight Control You can succeed in becoming and staying slimmer! This book is not a diet—it’s a comprehensive program that takes the reader beyond artificial“formula approaches.” 96 pgs, $7.95 Food for Life The breakthrough book on aging, heart disease, cancer, weight control, and general health. Preface by Dean Ornish, M.D. Loads of tips on changing your diet, 21 days of menus, plus delicious recipes by Jennifer Raymond. 334 pgs, $14.95 Building Bone Vitality A Revolutionary Diet Plan to Prevent Bone Loss and Reverse Osteoporosis Amy Lanou Ph.D., Michael Castleman Bone vitality doesn’t come through dairy products, calcium pill, or drugs. Using the latest clinical studies, Dr. Lanou explores the calcium myth and explains why a low-acid diet is the only effective way to prevent bone loss. 256 pgs, $16.95
From The Cancer Project
The Nutrition Rainbow Poster The more naturally colorful your meal is, the more likely it is to have an abundance of cancer-fighting nutrients. Pigments that give fruits and vegetables their bright colors represent a variety of protective compounds. The Nutrition Rainbow poster shows the cancer-fighting and immuneboosting power of different-hued foods. 17”x22”$6.00 , Prescription for Life Poster This whimsical work of art introduces your patients to the importance of fruits, vegetables, whole grains, and beans in cancer prevention and survival. It also tells how to obtain free information about nutrition, recipes, and classes from The Cancer Project. 17”x22” , $6.00 New VersioNs The Cancer Survivor’s Guide Neal Barnard, M.D., Jennifer Reilly, R.D. Find out how foods fight cancer and the advantages of a high-fiber, low-fat, dairy- and meat-free diet. Includes updates from the latest research, special prostate and breast cancer sections, tips for making the dietary transition, and more than 130 recipes. 245 pgs, $19.95 Eating Right for Cancer Survival dvd Neal Barnard, M.D., Chef Sualua Tupolo, Stephanie Beine, R.D. This exciting 2-disc set is designed to work hand in hand with the companion book, The Cancer Survivor’s Guide. Nine nutrition presentations and nine cooking lessons provide powerful tools for making changes in health and well-being. 270 mins, $19.95
The Kind Diet Alicia Silverstone, Introduction by Neal Barnard, M.D. Deliciously empowering, The Kind Diet opens the door to effortless weight loss, high energy, clear skin, and smooth digestion, all while protecting the planet. Three separate dietary tracks—from Flirting to Superhero—help readers make the vegan transition at their own pace. Discover food that satisfies at every level. Hardcover, 320 pgs, $29.99
Summer 2010 GOOD MEDICINE Summer 2010 GOOD MEDICINE
Many PCRM fact sheets and booklets, including our popular Vegetarian Starter Kit, are available without charge at PCRM.org/Resources Packed with Plant Power Lunch Tote Bag Share your enthusiasm for a vegan diet with this insulated 8.5x6x6-inch lunch bag with zippered top, front pocket, and 32-inch shoulder strap, $9.95
National Conference on Childhood Obesity DVD Hear 13 top researchers speak out on the roles of nutrition and public policy in combating the epidemic. Recorded at the 2009 conference. 2 disks. 4 hrs, 20 mins. $19.95
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Cat Magnetic Bumper Sticker $2.00 Power Plate Poster “These healthful food groups help you live longer, stay slimmer, and cut your risk of heart disease, diabetes, and high blood pressure.“ 18"x 24", $6.00
Monkey Refrigerator Magnet 2"x3½". $1.00 Rabbit Refrigerator Magnet 2"x3½". $1.00
Go Vegan Multilingual Apron Veg-friendly phrases in ten languages. 21"x 28" gourmet apron with pocket. Cream on forest green. $13.95
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Summer 2010 GOOD MEDICINE Winter 2006
Just the Facts
More Than He Could Chew When Chad Ettmueller of Cumming, Ga., tried to eat a double-meat, double-cheese sandwich, loaded with five types of meat and three types of cheese, he ended up in the hospital with a dislocated jaw. Doctors were able to surgically treat him 14 hours later. It’s All in the Delivery looking for a good vegan meal and don’t want to go out? VeggieBrothers.com ships more than 100 vegan items—soups, appetizers, main dishes, desserts— anywhere in the united States and Canada. University Violations The u.S. Department of Agriculture reported nine animal welfare violations after an inspection of the laboratories at the university of utah. Violations included animals not receiving antibiotics or pain medications in a timely manner, a too-crowded guinea pig enclosure, and the death of a kitten who had been given too much dextrose. Punishments for animal welfare violations are notoriously light. In this case, the university received only warnings. Chimpanzee Behavior Chimpanzees grieve over death very much as humans do, according to new research papers published in the journal Current Biology. Researchers observed chimpanzees grooming and attending to a dying elderly female chimpanzee and remaining subdued for weeks after her death and mothers refusing to accept the death of their babies and holding the infants’ bodies for weeks, among other behaviors. An Apple Cider a Day The New Hampshire House of Representatives voted 230 to 74 to make apple cider—rather than milk—the official state beverage. The initiative was introduced at the urging of a fourth-grade class. Go Green, Save Green Air India employees in Delhi have offered to go vegetarian as part of the airline’s costcutting measures. The 700 to 1,100 employees served daily will skip the chicken that had been offered in the company café three times a week. A Healthy Holiday The San Francisco Board of Supervisors unanimously approved a resolution encouraging residents to observe meat-free Mondays. Citing the health and environmental benefits of vegetarian meals, the resolution urges restaurants, schools, and grocery stores to add more vegetarian options.
pCrm illUStrationS/doUG Hall
Experiments Suspended for Mistreatment of Animals The university of WisconsinMadison has suspended Michele Basso, who studied Parkinson’s disease and other brain disorders, from working with animals for what officials call a clear pattern of problems with animal welfare. Problems cited included instances in which monkeys suffered fatal brain injuries.
Lufthansa Bars Animal Shipments lufthansa Airlines will no longer transport dogs and cats destined for laboratories. Customers were outraged after seeing photos of distressed beagles being shipped to a Charles River laboratories facility in Scotland, where they were likely poisoned in drug and pesticide tests.
Summer 2006 GOOD MEDICINE Winter 2010 GOOD MEDICINE
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A Star Pediatrician
Jay Gordon, M.D.
ediatrician Jay Gordon, M.D., lets his patients and their families know about the importance of good nutrition the moment they walk into his waiting room. Fresh fruits and vegetables are delivered to the office twice a week from a co-op. Fast food is strictly prohibited. In the middle of his residency, Dr. Gordon realized that he needed greater knowledge about infant and child nutrition to be able to help patients eat right to prevent disease. He took a senior fellowship in pediatric nutrition at SloanKettering Institute in New York City. Dr. Gordon now lives in the Los Angeles area, and many of his patients are children of Hollywood actors and actresses. Most days, he is up by 5 a.m., and starts seeing patients—often through home visits—well before 8 a.m. He also talks to parents about how they can improve the state of child nutrition. Part of the answer, he says, is “a complete revision of what’s in school lunch lines.” Dr. Gordon joined PCRM experts for a briefing on the Healthy School Meals Act
in March, and visited Members of Congress to urge them to co-sponsor the bill. In April, he appeared on Good Morning America to speak about the importance of plant-based school lunch options. Dr. Gordon also talks to parents about their own diets. He believes that for children to learn good eating habits, the whole family should follow a healthful diet. “If a father is 50 pounds overweight and saying he loves bacon, it sends the wrong message,” he says. “I talk with parents and help them change the way they eat.”
When talking with his young patients about nutrition, Dr. Gordon tries to focus on issues kids are interested in. “I talk to my 5-, 10-, 15-year-olds about red meat and cheese and ask them to think about what would be better for their Saturday afternoon soccer games,” he says. “I say, ‘If you eat more fruits and vegetables, you can run faster.’” “The way I handle my practice comes from a very personal issue,” he says. “I grew up in Wisconsin. My father had his first heart attack in his 30s. He then had surgery and was on many medications, and he could barely walk.” He says his father then tried a vegan diet and was able to get off all his medications. He lost 30 pounds and could walk two miles. “My father eventually backtracked and got back on the Wisconsin fast-food diet,” says Dr. Gordon. “He died at age 59.” Dr. Gordon is 62 years old and in great shape. He exercises for two hours every day and has followed a vegetarian diet for 35 years. “I’m battling my own genetic issues, and my weapons are soccer, tofu, and spinach—lots of spinach,” he says with a laugh.
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GOOD MEDICINE Summer 2010