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This experiment is to determine the neutralisation capacity of commercial antacid tablet.

Firstly, dissolve the tablet in an excess amount of acid of known concentration. Some of the HCl

will be neutralized by the carbonate, but there will be some remaining. Continue with a titration

with NaOH solution from experiment 2 to figure out the amount of excess acid. Then, from this,

calculate how much acid reacted with the antacid. This method of analysis is called a back-titration.

The reactions above are reversible, which means that CO2 dissolved in water will produce some

carbonic acid. This acid will react with the NaOH solution and the titrating and give us inaccurate

results. Therefore it is important to boil the solution when the carbonate reacts with acid, to remove

CO2 as a gas.


1. To prepare Hydrochloric Acid Solution.

2. To standardise the Acid against Sodium Hydroxide.

3. To determine Neutralisation Capacity of a Commercial Antacid Tablet.


This experiment is about neutralisation capacity of commercial antacid tablet. Firstly,

preparing an approximate concentration of hydrochloric acid solution and standardise against

standard sodium hydroxide solution from experiment 2. Hydrochloric acid is also not a primary
standard because its concentrated solution vaporises rapidly at room temperature. Once the

accurate molarity of the hydrochloric acid solution is known, t is referred as standard solution.

The neutralising capacity of the tablet is the amount of hydrochloric acid that it can

neutralise. The antacid tablet does not dissolve in water alone but requires the presence of HCl.

Since the HCl is excess, only some of the added HCl will react with the base present in the tablet.

The remaining amount of HCl is then analysed with the standard NaOH solution from experiment

2. The difference in the amount of HCl added initially in excess and the remaining HCl gives the

amount of HCl that reacts with the antacid and thus the neutralisation capacity of the antacid tablet.

The calculated amount of HCl that reacts gives the mass and percentage of hydroxide in the tablet.