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Motion sickness.

car sickness. fatigue. Depending on the cause.Motion sickness or kinetosis.] If the motion causing nausea is not resolved. Unlike ordinary sickness. Sopite syndrome in which a person feels fatigue or tiredness is also associated with motion sickness. it can also be referred to as seasickness.Nausea in Greek means seasickness (naus means ship). vomiting in motion sickness tends not to relieve the nause a. is a condition in which a disagreement exists between visually perceived movement and the vestibular system's sense of movement. the sufferer will usually vomit. and nausea are the most common symptoms of motion sickness. also known as travel sickness. . simulation sickness or airsickness. Dizziness.

• M.GIT. Causes. . is thought to be caused by conflect of massage to the brain .where the vomiting center receives information from eye .S.and vestibular system in the ear .

. • Can be prophylacticaly treated be the OTC. • Commonly accure to children. • Nausea • Some times vomiting • Pallor and cold sweat. SYMPTOMS. and can be selected to match the patient needs.

• Commenly accure in young children(over 2 years old ) • Incidance decreased with age . • Different dosage forms can be used for management according to the age variance . AGE.

• Asking about family member whom have pervious experience of M. . and then management used . Previous History.S.

• For long journey repeating the dose during travel is indicated . Mode of Ttravel –Length of Journey. • Length of journy is important for drug election(length of action of drug is varies ). • Drug should recomanded by pharmacist in good time brfore journey (once vomiting stated there is little that can be done ). .that been effective in practice .

children are less likely to experience symptoms if kept accupied by playing games (brain concentration). Mode of Ttravel –Length of Journey.that been effective in practice (sit of seat). • Reading exacerbates the feeling of nausea . . • Pharmaceutical advice . • For any method of travel .


Management. • Prophylacticaly treatment by OTC. medication • The basis of treatment depend the anticholenergic activity of drug used and antihistamin which have anticholenergic property .

• All have potential to cause drowsness and promethazine have sedation .S. • Cinnarizine. Antihistamines.are the are the effective for the mamagement of M. • Should avoided during pregnancy(eccept meclozin). • Meclazine and promethzine theoclats have long duration of action (long journey).Meclozine. .and Promethazine. • Cinnarizine and promethzine not recomanded for children younger than5 year • Meclozine can be given to those over 2 years.

*Anticholinergic drugs and antihistamines with anticholinergic effects are best avoided in patients with . *Anticholinergic drugs can cause drowsiness.blurred vision. *Hyoscine has a short duration of action(1-3)hr. Anticholinergic agents *The only anticholinergic used widely in the prevention of motion sickness in hyoscine hydrobromide (prototype).so its useful for shorter journeys and should be given 20 min.constipation and urinary retention. before the start of a journey.dry mouth. *children could be given sweets to suck to counteract any drying of the mouth.

Prostatic hyperatrophy because of the possibility of urinary retention and in glaucoma because the intraocular pressure might be increased.g amitriptyline).g haloperidol) and phenothiazines (e. *Pharmacists should remember that side-effects from anticholinergic agents are additive and may be increase in patients already taking drugs with anticholinergic effects .g chlorpromazine).butyrophenones(e.TCA(e.such as amantidine . .

it was found that ginger powder (Zingiber officinale) could be effectively reduce motion sickness .for whom other antiemetics such as anticholinergic and antihistamines are not recommended . Alternative approaches to motion sickness *Ginger . .since it does not cause drowsiness. *No mechanism of action has been suggested that ginger acts on the GI tract itself rather than on the vomiting centre in the brain or on the vestibular system .and might be worth considering for use in pregnant women . *Ginger would be woth trying for a driver who suffered from motion sickness.

Acupressure wristbands *Elasticated wristbands that apply pressure to a defined point on the inside of the wrists are now readily available *Such wristbands might be worh trying for drivers or pregnant women .