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Arbovirus

Genus Species Morphology Phathogenesis Clinical Diagnosis &


syndrome Treatment
Filoviridae Marburg Virus  Rna, + sense, Massive replication at Same as flu. PCR
Known as (panjang :665) single strands. endotel, monosit, (nausea, ELISA
African Dengue Epidem : rare case,  Diameter 80nm makrofag, dendrit dhiarrhea,
Zimbabwe and kenya. (murray) 70nm vomiting, Viral destroyed
(long filament) Reservoir : African (jawetz). Monosit elicit cytokines dyspnea, when dipanaskan
green mongkey,  Panjang 800- storms (superantigen headache) dalam 60 derajat
Cercopithecus 1400 nm like)extensive tissue celsius selama 30
aethiops Necrosis in parenchyma Viral menit dnegna UV
 Nucleocapsid liver, spleen, lymph node, haemmorhagic dan iradiasi
Ebola Virus helical lung fever Gamma dan
(panjang : 805)  enveloped pelarrut lipid dan
Epidem: zaire, sudan,  contain 1 Endothelial protein Death 90% pembilas dan
Liberia,sieraaleone, glycoprotein. adhesion will interfered, disinfektan
guinea Glycoprotein cause cytolysis  BSL 4 phenolic
Reservoir : kera menyusun duri widespread endothelial
sinomolgus ( Macaca trimer. vascular leakage 
Fascicularis) hypovolemic shock and Traeatment :
edema
(was classified as 1. antibody
rhabdoviridae) Gp can inhibit neutrophil containing
and antibody action serum
They maybe endemic 2. Artificially
in BAT and WILD Viral protein can inhibit produced
MONGKEY interferon production and antibody
action. ZAMPP
3. Interferon
Ebola virus will bind to 4. Ribafirin
niemann-pick c1 (NPC1), Hewan di slughter
cholesteros transfer
protein and TIM1 (t-cell Human
immunoglobulin and quarantined
mucin domain one) a
same receptor as hepatitis
A

Spread with contact


infected blood( human
syringe) or oral secretion
(biten by hewan) penjaga
monyet dan dokter hewan.