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Course Structure

B.TECH. 2nd Year (Biochemical Engineering Branch)
3rd Semester

Sl. Course Subject Credits Teaching Load Evaluation Scheme
No. Code (Hrs.) Sessional End Total
Lect. Tut. Prac. CT TA Total Sem.
Theory Courses
1 THU301 Engineering Economics 3 2 1 0 15 10 25 50 75
2 TBE301 Fundamentals of Biology 4 3 1 0 30 20 50 100 150
3 TBE302 Microbiology 4 3 1 0 30 20 50 100 150
4 TCH303 Fluid Flow & Solid Handling 4 3 1 0 30 20 50 100 150
5 TBE303 Bioanalytical Techniques 2 2 0 0 15 10 25 50 75
6 TME 303 Solid Mechanics 4 3 1 0 30 20 50 100 150
Practical Courses
7 PBE301 Microbiology Lab 2 0 0 3 15 10 25 50 75
8 PCH303 Fluid Mechanics Lab 2 0 0 3 15 10 25 50 75
9 PBE302 Bioanalytical Techniques Lab 1 0 0 2 15 10 25 25 50
10 GP-301 General Proficiency 1 - - - - - 50 - 50
TOTAL 27 16 5 8 1000

4th Semester

Sl. Course Subject Credits Teaching Load Evaluation Scheme
No. Code (Hrs.) Sessional End Total
Lect. Tut. Prac. CT TA Total Sem.
Theory Courses
1 TBE401 Downstream Processing 4 3 1 0 30 20 50 100 150
2 TCS407 CBNST 3 2 1 0 15 10 25 50 75
3 TBE402 Biochemistry 4 3 1 0 30 20 50 100 150
4 TBE403 Fermentation Biotechnology - I 2 2 0 0 15 10 25 50 75
5 TCH406 Industrial Fuels & Process 4 3 1 0 30 20 50 100 150
Calculations
6 TCH407 Chemical Engineering 4 3 1 0 30 20 50 100 150
Thermodynamics
Practical Courses
7 PCS407 CBNST Lab 1 0 0 2 15 10 25 25 50
8 PBE401 Biochemistry Lab 2 0 0 3 15 10 25 50 75
9 PBE402 Downstream Processing Lab 2 0 0 3 15 10 25 50 75
10 GP 401 General Proficiency 1 - - - - - 50 - 50
TOTAL 27 16 5 8 1000

B.TECH. 3rd Year (Biochemical Engineering Branch)
5th Semester

Sl. Course Subject Credits Teaching Load Evaluation Scheme
No. Code (Hrs.) Sessional End Total
Lect. Tut. Prac. CT TA Total Sem.
Theory Courses
1 TCH506 Heat Transfer Operations 4 3 1 0 30 20 50 100 150
2 TCH507 Mass Transfer Operations - I 4 3 1 0 30 20 50 100 150
3 TBE501 Bioprocess Engineering - I 4 3 1 0 30 20 50 100 150
4 TBE502 Waste Water Treatment 4 3 1 0 30 20 50 100 150
5 TBE503 Bioprocess Principles 2 2 0 0 15 10 25 50 75
6 TBE504 Fermentation Biotechnology – II 2 2 0 0 15 10 25 50 75
Practical Courses
7 PCH505 Chemical Engineering Operations 1 0 0 2 10 15 25 25 50
Lab
8 PBE501 Fermentation Lab 2 0 0 3 15 10 25 50 75
9 PBE502 Waste Water Analysis Lab 2 0 0 3 15 10 25 50 75
10 GP501 General Proficiency 1 - - - - - 50 - 50
TOTAL 26 16 4 8 1000

6th Semester

Sl. Course Subject Credits Teaching Load Evaluation Scheme
No. Code (Hrs.) Sessional End Total
Lect. Tut. Prac. CT TA Total Sem.
Theory Courses
1 THU601 Principles of Management 3 2 1 0 15 10 25 50 75
2 TBE601 Bioprocess Engineering – II 4 3 1 0 30 20 50 100 150
3 TCH606 Instrumentation & Process Control 4 3 1 0 30 20 50 100 150
4 TCH607 Chemical Reaction Engineering 4 3 1 0 30 20 50 100 150
5 TCH608 Mass Transfer Operations - II 2 2 0 0 15 10 25 50 75
6 TBE602 Genetic Engineering 4 3 1 0 30 20 50 100 150
Practical Courses
7 PBE601 Bioprocess Engineering Lab 2 0 0 3 15 10 25 50 75
8 PBE602 Genetic Engineering Lab 2 0 0 3 15 10 25 50 75
9 PBE603 Seminar 1 - - 2 - - 50 - 50
10 GP601 General Proficiency 1 - - - - - 50 - 50
TOTAL 26 16 5 8 1000

B.TECH. 4th Year (Biochemical Engineering Branch)
7th Semester

Sl. Course Code Subject Credits Teaching Load Evaluation Scheme
No. (Hrs.) Sessional End Total
Lect. Tut. Prac. CT TA Total Sem.
Theory Courses
1 TBE 701 Bioinformatics 4 3 1 0 30 20 50 100 150
2 TBE011-013 Professional Elective – I* 4 3 1 0 30 20 50 100 150
3 TBE021-023 Professional Elective - II* 4 3 1 0 30 20 50 100 150
4 TBE031-033 Professional Elective - III* 4 3 1 0 30 20 50 100 150
5 TBE061-064 Open Elective** -I 4 3 1 0 30 20 50 100 150

Practical Courses
6 PBE701 Project-I 3 0 0 6 -- 75 75 75 150
7 PBE702 Summer Training Report 1 0 0 2 -- 50 50 0 50
Evaluation & Viva*
8 GP801 General Proficiency 1 - - - - - 50 - 50
TOTAL 25 15 5 8 1000
*Note- Evaluation of 4-6 weeks Industrial training after VIth semester is to be done in VIIth semester.

Professional Electives (Proposed)

Professional Electives
TBE01: Professional Elective – I*
TBE011 : Enzyme Engineering TBE012: Creativity, Innovation and Product Development
TBE013: Modelling and Simulation of Bioprocesses TBE 014: Biopharmaceutical Technology
TBE02: Professional Elective – II*
TBE021: Bioethics, Biosafety & IPR TBE022: Biomaterial Science and Technology
TBE023: Advanced Bioseparation Processes TBE 024: Solid State Fermentation
TBE03: Professional Elective – III*
TBE031: Environmental Biotechnology TBE032: Immunology
TBE033: Preservation of Biomaterials TBE 034: Secondary Metabolites

***Open Elective (Code to be referred from combined list)

TBE061: Nanobiotechnology TBE062: Biosensors
TBE063: Environmental Biotechnology TBE064: Bioinformatics

B.TECH. 4th Year (Biochemical Engineering Branch)
8th Semester

Sl. Course Code Subject Credits Teaching Load Evaluation Scheme
No. (Hrs.) Sessional End Total
Lect. Tut. Prac. CT TA Total Sem.
Theory Courses
1 TBE801 Bioprocess Plant Design and 4 3 1 0 30 20 50 100 150
Economics
2 TBE041-TBE043 Professional Elective – IV* 4 3 1 0 30 20 50 100 150
3 TBE051-TBE053 Professional Elective - V* 4 3 1 0 30 20 50 100 150
4 TBE 071-074 Open Elective** -II 4 3 1 0 30 20 50 100 150

Practical Courses
5 PBE801 Bioprocess Plant Design Lab 1 0 0 2 15 10 25 25 50
6 PBE802 Project-II 6 0 0 12 -- 150 150 150 300
7 GP801 General Proficiency 1 - - - - - 50 - 50
TOTAL 24 12 4 14 1000

Proposed Electives:

Professional Electives
TBE04: Professional Elective – IV*
TBE041: Nanobiotechnology TBE042: Food Biotechnology
TBE043: Industrial Safety & Hazard Management TBE044: Molecular Modeling and Drug Design
TBE05: Professional Elective – V*
TBE051: Animal Biotechnology TBE052: Genomics & Proteomics
TBE053: Plant Biotechnology TBE054: Non Conventional Energy Resources
***Open Elective (Code to be referred from combined list)
TBE 071:Food Biotechnology TBE 072:Bioethics, Biosafety & IPR
TBE 073:Fundamentals of Biology TBE 074:Biomaterial Science and Technology

** Open Elective course: Offered for other departments.

Total credits for all semester: 210

B.TECH. 2nd Year (Biochemical Engineering Branch)
3rd Semester
Theory courses

THU301: Engineering Economics
L T P 2 1 0
UNIT I
Time value of money : Simple and compound interest, Time value equivalence, Compound interest
factors, Cash flow diagrams, Calculation, Calculation of time –value equivalences.
Present worth comparisons, Comparisons of assets with equal, unequal and infite lives, comparison of
deferred investments, Future worth comparison, payback period comparison.
UNIT II
Use and situations for equivalent annual worth comparison, Comparison of assets of equal and unequal
life. Rate of return, Internal rate of return, comparison of IIR with other methods, IRR misconceptions.
UNIT III
Analysis of public Projects: Benefit/ Cost analysis, quantification of project, cost and benefits, benefit/
cost applications, Cost –effectiveness analysis.
UNIT IV
Depreciation, computing depreciation charges, after tax economic comparison, Break-even analysis;
linear and non-linear models.
Product and Process Costing, Standard Costing, cost estimation, Relevant Cost for decision making, Cost
control and Cost reduction techniques.

Text Book :
1. Horn green, C.T., Cost Accounting, Prentice Hall of India
2. Riggs, J.L., Dedworth, Bedworth, D.B, Randhawa, S.U. Engineering Economics, McGraw Hill International
Edition, 1996

TBE301: Fundamentals of Biology
L T P 3 1 0
UNIT -I
Characteristics of living systems; Classification of the living organisms (five kingdom classification,
major groups and principles of classification within each kingdom). Systematic and binomial system of
nomenclature. Prokaryotic and eukaryotic cell; Plant and animal cell.
UNIT -II
Cell cycle, mitotic and meiotic cell division; Cell organelles and their function; respiration and
photosynthesis processes.
UNIT –III
Mendelian inheritance, linkage, crossing over, Sex determination, Concept of genes and gene
organization, genetic code, mutations.
UNIT - IV
Tissues in animals and plants; Morphology, anatomy and functions of different parts of flowering plants:
Root, stem, leaf, inflorescence, flower, fruit and seed.
UNIT – V
An introduction to Immunology; innate and acquired immunity, Various cells and organs involved in
immune response, Nature of antigens, epitopes and haptens, Structure and classes of antibody

Krieg. Jr. Nutrition. Gardener. maintenance and preservation of cultures. ultrastructure. E.D. distinguishing features and economic importance. Biodegradation and Bioremediation Text Books: 1. Ganguly. Immunology 6th edition by Kindt. Hagerstorn TCH303: Fluid Flow & Solid Handling L T P 3 1 0 . Chan and N. H. Morphology. Das and Datta.B.C.Text Books: 1. . W. Algae and their classification. isolation of aerobic and anaerobic microbes. nutrition. 2. Guisberg. goldsby.H. Simmons & Snustad. Gupta. Microbiology by M. Physical and chemical methods of control of microorganisms. other characteristics and applications of fungi. Kathleen Talaro & Arthur Talaro. Distinguishing features and applications of actinomycetes. UNIT V Microbial ecology. Transduction. nature and multiplication of viruses (plant. Eisen & H. aim and scope. Ajay Poul. Pelczar. W.C. Osborne. R. “Text Book of Cell and Molecular Biology” Books and Allied(P) (2007). “Genetics-Classical to Modern” Rastogi Publication(2007).(1991). Reference Books: 1. Growth and multiplication in bacteria. Brown Publishers (1994). “Foundation in Microbiology”. food and air. Occurance of microorganisms in soil.J. 5th Ed. “College Botany” New Central Book Agency(2007). Microbiology. TMH Book Company. Historical background. Wm. Methods of genetic recombination in bacteria: Transformation. Brief idea of food borne infections and poisoning organisms. UNIT IV Pure culture techniques – microbial culture media. “Genetics” John Wiley & Sons. yeasts and cyanobacteria UNIT III Morphology.freeman and Company. identification. Reference Books: 1. Dulbecco. C. Immunology: Introductory text book by Nandini Shetty. K. 3.S. 2. N. Physiology. Inc. enumeration and staining techniques. New York 5. Harper and Row Publishers. reproduction. P. characteristics of pure culture. Conjugation UNIT II Ultrastructure. S. B.R. animal and bacteriophages). Davis. New Age International Publishers TBE302: Microbiology L T P 3 1 0 UNIT I Introduction. water. cultivation of viruses. 4.

5th ed: John Wiley (1998). Introduction to fluidization. Gel chromatography. Flow of solids through fluids.S. power requirement and mechanism. Fox. Transport of fluids. size reduction of solids. UNIT III Fluid flow: Properties of fluids Fluid statics: Hydrostatic Law and Pressure Measurement. Rotameter and Pitot tube. Ion exchange chromatography.al. classification and sedimentation. rotary pumps. grinders. UNIT V Pumping and Compressing: Reciprocating pumps. UNIT IV Electrophoresis: . minor losses in pipe flow. and conveyors. “Introduction to Fluid Mechanics”. intermediate and fine size reduction. Electron microscopy: TEM and SEM. Nozzle and Venturimeter. energy relationships. Atomic force microscopy and confocal microscopy. “Principles of Unit Operations” John Wiley TBE303: Bioanalytical Techniques L T P 2 0 0 UNIT I Spectroscopy Interaction of EM radiation with matter: Overview of Electromagnetic spectrum. MALDI. Determination of particle size. Partition and adsorption chromatography. UV-Vis spectrophotometer: Principle. Planner Chromatography. Beer-Lambert's Law. R. TLC). Screening. McCabe Smith. Differential interference contrast microscopy. UNIT III Chromatography Chromatography: Basic theory and principles of Chromatography. Screen analysis. S. continuous and batch equipments. Fluorescence. Instrumentation. Power driven machines: Crushers.K. et. Basics of IR and NMR and their application in biotechnology and Basics of X- Ray diffraction analysis and their application in biotechnology UNIT II Microscopy methods Bright Field. Phase Contrast. McGraw Hill References: 1. “Unit Operations in Chemical Engineering”. working and Application Atomic spectroscopy: Principles and application of Atomic Absorption / Emission Spectrometer. S.A. Foust A. (Paper Chromatography. Text Books: 1. 2. UNIT IV Flow Measurements: Orifice meter. Series and Parallel arrangements of pumps. & McDonald. Dark Field. operating variables. pipe fittings. stages of reduction . Katria and Sons. centrifugal pumps and blowers.) 3. Delhi (1998. Mass Spectroscopy..UNIT I Solids and Their Handling: Properties of solids. industrial screening equipments. "Fluid Mechanics". Kumar D. UNIT II Filtration: Theory.

S. Donald M. Immunoelectrophoresis Techniques. Wilson. Wiley Interscience 2. J. compatibility relations. TME303: Solid Mechanics L T P 3 1 0 UNIT I Introduction.: Principles and Techniques of Practical Biochemistry. P. Fundamentals of Analytical Chemistry by Douglas A. Material properties for isotropic materials and their relations. Fluorescence Activated Cell Sorter. Cambridge 1999. Stanley R. Mohr's circle representation. Text Books: 1. Cauchy stress tensor. Alex Williams. 1986 4. torsion. C. Mechanics of Materials by Bear Jhonson . Stresses and deflections due to transverse shears. combined stresses. An Introduction to the Mechanics of Solids. UNIT III Shear Force and Bending Moment diagrams. Theories of failures for isotropic materials. 1990 2. C. Dahl. SDS PAGE. pulse field gel electrophoresis and western blotting. Castigliano's theorem. K. Lardner. N. Engineering Mechanics of Solids. Handbook of Analytical Techniques Published Online: 2008. West. bending and transverse shear. References: 1. I. Shames. UNIT IV Deflections due to bending: moment-curvature relation. CBS publ. J. Walker. 2-D electrophoresis. stress and strain invariants. Timoshenko. 5th Ed. Stress and strain: stress at point. H. electrophoresis of protein-PAGE. reciprocity theorem etc. UNIT V Immunological Techniques: Immunodiffusion. area moment method.. Prentice Hall. Helmut Günzler. ELISA. Publisher: Brooks Cole. 1989 3. McGraw Hill. S. Prentice Hall. Crouch. Stresses due to bending: pure bending theory. UNIT II Constitutive relations: true and engineering stress-strain curves. E. RIA. analysis of deformation and definition of strain components. F. Isoelectric focusing of protein. equilibrium equations. James Holler. Agarose electrophoresis of nucleic acid. Axially loaded members.Electrophoresis : Theory of electrophoresis. load-defection differential equation. P. vols. Introduction to Solid Mechanics. 2e. UNIT V Torsion of circular shaft. Torsion of circular shafts. and T.Cambridge University Press. .1978. principal stresses and strains. 2e. Energy methods: Strain energy due to axial. Strength of Materials. Crandall. Skoog. 1 & 2. Text Books: 1.. and superposition theorem. Popov. References: 1.

Viable cell count (By pour plate method) Turbidity measurement as direct expression of growth. 14. Micrometry: Measurement of microbial cells. Microscopy : Use & care of microscope. yeast and molds. Microbiological examination of water: Coliform & Salmonella counts. Isolation of microorganisms by streak plate method. Isolation of microorganisms by streak plate method. Microbiological assay of a growth factor. Endospore staining. 3. examination of prepared slides and wet mounts of bacteria. Microbial Identification & examination of food samples. Influence of antimicrobial agent on growth effect of UV radiation & heat on microbial growth. yeast. 2 Compute component of given percentage solution. Gram staining. yeast and molds. Gram staining. Micrometry: Measurement of microbial cells. 10. Microscopy : Use & care of microscope. 11. Viable cell count (By pour plate method) Turbidity measurement as direct expression of growth. 14. Staining techniques: Simple staining. Isolation by serial dilution method. Laboratory Courses PBE301: Microbiology Lab L T P 0 0 3 1-2. Culture techniques: Culture media preparation. yeast. Isolation by serial dilution method. PCH303: Fluid Mechanics Lab L T P 0 0 3 1-2. Capsule staining. 3. 4. Capsule staining. 4. PPS solution and stock solution. Enumeration techniques: Microscopic count using haemocytometer. maintenance & preservation. 11. molarity solution. Culture techniques: Culture media preparation. 13. Cultivation of microorganisms. PBE302: Bioanalytical Techniques Lab L T P 0 0 2 1 Introduction to quality control. 5-7. maintenance & preservation. molds. 10. Other biomaterials of bacteria. Enumeration techniques: Microscopic count using haemocytometer. 12. Influence of antimicrobial agent on growth effect of UV radiation & heat on microbial growth. Microbial Identification & examination of food samples. Staining techniques: Simple staining. PRN. 13. 3 pH meter : . Microbiological examination of water: Coliform & Salmonella counts. Use concepts of accuracy and precision. Other biomaterials of bacteria. 5-7. molds. 8-9. 8-9. examination of prepared slides and wet mounts of bacteria. Endospore staining. Microbiological assay of a growth factor. Cultivation of microorganisms. 12.

Solvent-solvent extraction of plant pigmnets. protein) solution. .Use of paper chromatography for separation of plant pigments .Use of thin-layer chromatography for amino acid (TLC) . .Measure components and working of centrifuges.Demonstration of Gel-exclusion chromatography 7 Electrophoresis: Electrophoresis of protein by SDS-PAGE 8 Demonstration of Sterilization of solution by filteration 9 PCR 10 Demonstration of Dialysis . measurement.Preparation of solution using pH meter. solving g and RPM of centrifuge with respect to various heads. detailed diagram of pH electrod and reference electrode (combined electrod also).To determine maximum absorption spectra of mixtures (potassium dichromate and potassium permanganate.Demonstration of Ion-exchange chromatography .Isolation of cellular organelles by differential centrifugation 6 Chromatography : . . 5 Centrifugation : . troubleshouting. rotors . .Demonstration of the effect of the solution 4 Spectroscopy : . find pH of a solution giving detailed account of pH meter operation.List uses of pH meter.

B. organic solvents. Reed. Reverse osmosis. Biotechnology. Penicillin G . Bioseparation Techniques. Dialysis. UNIT IV Membrane based Separation -micro and ultrafiltration (Theory. Use of Extraction and Adsorption for bioseparation. Affinity chromatography UNIT V Crystallization. Vol. J. HPLC .Murray Moo-Young. International Methods of Analysis.Wilson and Golding.Vol. Prentice-Hall of India. Cambridge University Press 4. II-latest ed. Hydrophobic Interaction Chromatography. Handbook of Analytical techniques-H. Glutamic acid. 2. Role of Downstream Processing in Biotechnology. Cell Disruption methods (Physical. Precipitation methods. FPLC. Pretreatment of broths.use of neutral salts. Design and Configuration of the Equipment). 2nd Year (Biochemical Engineering Branch) 4th Semester Theory courses TBE401: Downstream Processing L T P 3 1 0 UNIT I An overview of Bioseparation. Reversed Phase Chromatography. Wiley Publications..Extracellular Enzymes. Butterworth Publication TCS407: CBNST L T P 2 1 0 . Rehm and G. biomass. 6. Sivasankar. Equipment. CBS Publication. Electrodialysis. Product Recovery in Bioprocess Technology. References: 1.. Ultracentrifugation. Drying. Pergan Publishers. 5. Filtration: Theory. Problems and requirement of bioproduct purification. Removal of insoluble. High molecular weight polymers.TECH. 2004. Intracellular enzymes. Heinemann. use and design of different types of rotors. Cost cutting strategies.Willard et al. 5. A Biologist’s Guide to Principles & Techniques of Practical Biochemistry. UNIT II Primary separation and Recovery Process: Conditioning of broth. Verlag Publishers 3.. UNIT III Centrifugation: Theory and types of centrifugation and sedimentation. chemical and Enzymatic) for intracellular products. Chromatographic technique for detection and mass scale production of biomolecules: GLC. 4. 3. Antibodies and protein exclusion bodies Text books: 1. Gunzler. A Few case studies of downstream processing: Citric acid. Types of centrifuges. Comprehensive biotechnology. H.

Mathematical preliminaries. Statistical Quality Control methods. Firewall Media. “Computer Oriented Numerical Methods”. Newton Divided difference formula. Jain. “Numerical Methods for Scientific and Engineering Computations”. Newton-Raphson method. M. Error in a series approximation. analysis and algorithms . TBE402: Biochemistry L T P 3 1 0 Unit-I Overview of Structure and function of biomolecules. 4. Rajaraman V. “Introduction to Statistical Methods”. Boole’s rule. lipids and nucleic acids. General error formula. “Numerical methods in Engineering and Science”. Francis Scheld. TMH 3. Bessel’s. 7. Methods of finding complex roots. Delhi. 30. Data fitting with Cubic splines. Interpolation with unequal intervals: Langrange’s Interpolation. Protein folding mechanisms. Waddle’s rule. Khanna Publishers. AW 2. UNIT IV Statistical Computation: Frequency chart. Pearson Education. Pearson Education 2.UNIT I Introduction: Numbers and their accuracy. Runge-Kutta Methods. polynomials. Muller’s method. Pradip Niyogi. ” Numerical Analysis”. Iteration method. Errors and their Computation. Euler’s Method. “Applied Numerical Analyses”. Numerical differentiation Numerical Integration: Trapezoidal rule. Linear and Non linear Regression.Srimamta Pal (Oxford Higher ed) 5. Polynomial Equations.B. Protein metabolism. Difference tables Polynomial Interpolation: Newton’s forward and backward formula Central Difference Formulae: Gauss forward and backward formula. TMH 6. Goyal. 20. Predictor Corrector Methods. Everett’s formula. .. Sastry S. fitting of straight lines. Solution of Algebraic and Transcendental Equation: Bisection Method. Automatic Error Monitoring and Stability of solution. S. 10. Curve fitting by method of least squares. Iyengar and Jain. Solution of differential Equations: Picard’s Method. Computer Arithmetic. Multiple regression. Amino acids and their polymerization into proteins. Rate of convergence of Iterative methods. “Numerical Analysis and Algorithms”. Regression Analysis. Grewal B S. and 40 level of protein structure. Method of false position. Text Books: 1. exponential curves etc. UNIT II Interpolation: Finite Differences. Hermite’s Interpolation UNIT III Numerical Integration and Differentiation: Introduction. “Introductory Methods of Numerical Analysis”. New Delhi. Vikas Publishing. Protein sequencing methods. carbohydrates. Gerald & Whealey. Vijay Gupta. Stirling’s. 3. Numerical Method Principles. Gupta C. Simpson’s 1/3 and 3/8 rule. “Computer Based Numerical and Statistical Techniques”. proteins. Taylor’s Method. New Age Int References: 1.

Unit-III Carbohydrates. glycerol metabolism. UNIT III Glycerol fermentation. TCA cycle. Unit-V Photosynthesis: light reactions and light independent reactions. “Biochemistry”. “General Biochemistry”. Beer production: Malting and brewing. References: 1. Pentose Phosphate Pathway. Weil. cell cultivation types: surface. lactic acid and vinegar. biosynthesis of fatty acids and triacylglycerol. Protease and Lipase. UNIT II Developments in alcohol fermentation processes. Wine and distilled liquors. UNIT IV Amino acids: Lysine and glutamic acid. New York.M. Lehninger. factors affecting the bioprocesses. Phosphoketolate pathway. Lipid metabolism. Nucleic acid metabolism. Major anabolic and catabolic pathways of carbohydrate metabolism and their regulation: Glycolysis. Microbial production of citric acid.H. Freemen & Co. and Vitamins and hormones. transport and oxidation of fatty acids in animal tissues.L. Galactose metabolism. Commercial enzymes production: Amylase.Enzymes and their action. 2. key bioreactor parts and assembly of bioreactors. N. Unit-II Nucleic acids and their polymerization. “Principles of Biochemistry”. Biological membranes and transport across them: passive. . Neston. Vitamin production through fermentation: Vitamin B12. Lubert Stryer. mechanism and development of MM kinetics. Glyoxilate cycle. A. New Age International (PLD). Riboflavin. their structure and polymerization. Spirit production. Text Books: 1. Membrane formation.L. TBE403: Fermentation Biotechnology – I L T P 2 0 0 UNIT I Fundamentals of fermentation processes: design of media. Gluconeogenesis. UNIT V Biomass as a fermentation product: Baker’s yeast. Text Books: . Entner- Duodoroff pathway. mechanism and biosynthesis of DNA and RNA. Signal peptides.H. Electron Transport and Oxidative Phosphorylation. DNA & RNA structure. J. W. Packing of DNA and DNA sequencing. facultative and active transport. Types of inhibitors and its effect on Vmax and Km. Amyloglucosidase. Factors affecting photosynthesis. D. Turn over number. Unit-IV Lipids and their classification. inoculum development. Cox. microbial proteins. CBS Publishers & Distributors. submerged and solid state fermentation for growth and non-growth associated products.

Material balances: Material balances with and without chemical reaction. Dunn. Fuel characteristics. Tata McGraw Hill (1984) TCH407: Chemical Engineering Thermodynamics L T P 3 1 0 UNIT I Basic Concepts and Definitions System. “Industrial Microbiology”. Types of liquid fuels. UNIT II Coal: origin and formation.J. crystallization and evaporation. Text Books: 1. liquid and gaseous fuels. Prentice Hall (1996). H. Hougan D. control of combustion. extraction. solubility and heat capacity. 6th ed. UNIT V Thermochemistry and energy balances. Property. specification of fuel oil. Stoichiometry and composition relations. “Industrial Microbiology”.. 3. Asia Publishing House. Microscopic Viewpoint. Modified and synthetic fuels. R. Perlman. "Basic Principles and Calculations in Chemical Engineering". storage. 3rd edition. Thermodynamic Equilibrium. TCH406: Industrial Fuels & Process Calculations L T P 3 1 0 UNIT I Fuels: Origin. Prescott and C. S. fuels for cryogenic engines.. Surroundings. References: 1. drying.M. References: 1.M. Types of gaseous fuels. Academic Press. coal tar and its distillation products. New York. Humidity and solvent recovery.C. Work. Vol.M. Types of solid. Felder. Peppler and D. filtration.M. work interaction between a system and surroundings. A. Material balance in unit operations. Bhatt. R. "Stoichiomerty" IInd edition. Energy balances for typical processes. L.II.E. Casida Jr. “Microbial Technology”. pdV-work. petroleum and its distillation products. "Elementary Principles of Chemical Processes ". 2. Distillation. McGraw-Hill Book Company. “Chemical Process principles”. UNIT IV The use of ideal gas laws and vapour pressures. Proximate and ultimate analysis of coal. centrifugation. John Wiley. i. chemical composition. UNIT III Process calculations: Systems of units. 2. Watson K. and general uses of industrial fuels.G.e. A. & Rousseau. and Ragatz R. Macroscopic.W. and Vora S.(1999). classification. D. Introduction to biofuels. Wiley Eastern Ltd.1. B. UNIT II First Law of Thermodynamics . Himmelblau.I. Inc. Energy. New York.

Polytropic Process). Energy Reservoirs. Thermodynamics”. V. Specific Heat Relations. 5. Heat Engine. New York. To implement Numerical Integration using Trapezoidal. To implement Newton’s Divided Difference and Langranges Interpolation formula. Carnot Theorems. To Find out the root of the Algebraic and Transcendental equations using 3. Heat of Reaction. Temperature Dependence of the Heat of Reaction. Bessel’s. degree of Reaction. 6. Absolute Entropy and the third law of thermodynamics. 8. First Law analysis of Elementary Processes(Constant Volume Process. 2. Applications to steady . UNIT IV Properties of Pure Substances Pure Substance. Chemical Exergy. Statements of Second Law of Thermodynamics. Perpetual Motion Machine of the First Kind. frequency curve and pie-chart etc.. J. unsteady flow and other engineering problems. Adiabatic Process. Refrigerator. 2. Irreversible Process. Concept of Phase. P. Equations of State. UNIT V Reactive Systems Stoichiometric coefficients. Measurement of steam quality. Reversible Process. To draw frequency chart like histogram. Isothermal Process. Applications to engineering problems. 9. Holman McGraw-Hill Book Company. Dryness Fraction. Types of Irreversibility.Conservation of energy. Perpetual Motion Machine of the Second Kind.. Available Energy. Products. To deduce error involved in polynomial equation. Carnot Cycle. UNIT III Second Law of Thermodynamics Limitations of First Law of Thermodynamics. Heat Pump. Maxwell’s Relations. To implement Gauss Forward and Backward. Constant Pressure Process. Applications to systems of engineering interest. Simpson 1/3 and Simpson 3/8 rule. P-V and P-T Diagrams of a pure substance. To implement Newton’s Forward and Backward Interpolation formula. Reactants. dead State and Availability. Steam Tables. Van Ness. A Textbook Of Chemical Engineering Thermodynamics” Narayanan K. Gibbs Phase Rule. To implement Least Square Method for curve fitting. Prentice-hall Of India Pvt Ltd. J. M. Second law efficiency of a reactive system. Liquid-Vapour mixtures. Entropy Principle of Entropy increase. Changes in thermodynamic properties and their inter-relationships. Law of mass action. Text Books: 1. References: 1. Laboratory Courses PCS407: CBNST Lab L T P 0 0 2 Write Programs in ‘C’ Language: 1. Smith and H. Sterling’s and Evertt’s Interpolation formula.C. To implement Numerical Differentiations. McGraw- Hill Book Company. New York. Ideal Gas. “Introduction to Chemical Engineering Thermodynamics”. 7. 4. .

Cell fractionation. Cell disruption techniques. High-resolution purification 6. Extraction of Lipids. 7. 8. 3. 9. PBE401: Biochemistry Lab L T P 0 0 3 1 Estimation of carbohydrates. Preparative liquid chromatographic techniques 7. two-phase aqueous extraction) 5. 2. PBE402: Downstream Processing Lab L T P 0 0 3 1. Separation of sugars by paper chromatography. To estimate regression equation from sampled data and evaluate values of standard deviation. regression coefficient. Estimation of proteins. Thin layer Chromatography. ultra filtration. 2. Solid separation methods-filtration. 6. value of R2 for atleast two independent variables. Separation of amino acids by paper chromatography. Isoelectric precipitation. Product crystallization and drying . Centrifugation techniques 4. t- statistics. 11. Estimation of nucleic acids: 4. Identification and estimation of an intermediate of EMP pathway. 3. 10 Assay of enzyme activity and enzyme kinetics. 12. Product enrichment operations (precipitation. 5. sedimentation techniques. Gel Electrophoresis. 10.

TCH507: Mass Transfer Operations – I L T P 3 1 0 UNIT I . film wise and drop wise condensation. composite layers etc. Natural and forced convection. black body and gray body concepts. Kern. loading in condensers and basic calculation on condensers. Badger. through plane walls. Insulation materials .. L. Common failures in heat exchangers. P. critical and optimum insulation thickness.. W. 3. Dimensional analysis. “Process Heat Transfer”. “Heat Transmission”. cylindrical and spherical surfaces . UNIT III Radiation: Basic laws of heat transfer by radiation. Conduction: Basic concepts of conduction in solids. UNIT II Convection: Fundamentals of convection. Correction factors. McGraw Hill (1989). Shell and Tube heat exchangers. McAdams. T. solar radiations. viz. “Heat Transfer”. Extended surfaces. Kirchhoff’s law.. boiling heat transfer coefficients.. McGraw-Hill (1954). steady state temperature fields and one dimensional conduction without heat generation e.TECH. Fouling factors. fines and their practical applications. UNIT IV Heat transfer with phase change : Condensation of pure vapors. Q. 2. convection and radiation. J. 9th ed. determination of individuals and overall heat transfer coefficients and their temperature dependence. double pipe. 3rd Year (Biochemical Engineering Branch) 5th Semester Theory courses TCH506: Heat Transfer Operations L T P 3 1 0 UNIT I Introduction to heat transfer and general concepts of heat transfer by conduction. References: 1. “Introduction to Chemical Engineering”. LMTD. combined heat transfer coefficients by convection and radiation. principles and design criteria. view factors.g. J. McGraw Hill Book (1950). laminar and turbulent heat transfer inside and outside tubes .B. UNIT V Heat transfer equipment: Classification. basic concept of convection and definitions . & Bancharo. Text Books: 1. heat transfer in boiling liquids. D. H. Types of Exchangers. W.. Holman. Tata McGraw Hill. 3rd ed. liquids and gases . Prevention of fouling. heat exchanger effectiveness.

methods of air sterilization. rotary driers.. selection of solvent. design equations for packed column.al. UNIT III Distillation : Entrainment. L. HTU. 3rd ed. McCabe Smith. history and scope of Biochemical Engineering.Basic Principles of mass transfer: Molecular diffusion in fluids. Macabe Thiele and Ponchon method for binary component distillation of azeotropes. K. Text Books: 1. UNIT V Drying: Batch and freeze drying. R “Mass Transfer Operations”. S. enthalpy. McGraw Hill.. Sherwood T. “Unit Operations in Chemical Engineering”.. mass transfer coefficients. triangular diagrams. Foust A. Unsaturated vapour gas mixtures. “Principles of Unit Operations” John Wiley (1980). Sterilization of air: Principles. UNIT III Aeration and agitation: Oxygen transfer in microbial systems. concept of maintenance energy. pressure drops . Monod kinetics and its limitations.. disadvantages of batch reactors. (1980). power requirements in gassed and ungassed bioreactors. flooding . UNIT II Absorption and Stripping: Equipments. Extractive distillation. et. Treybal. Interphase mass transfer. Pigford R. continuous sterilization process and its advantages. UNIT II Sterilization of media: Principles. graphical and analytical methods. mass transfer theories. absolute humidity. Humidification Operations: Vapour pressure. substrate utilization. design of air filters. Different biochemical unit operations and processes. rheology of fermentation fluids UNIT IV Kinetics of microbial growth. etc. measurements of volumetric mass transfer coefficient. repetitive batch fermentation. TBE501: Bioprocess Engineering – I L T P 3 1 0 UNIT I Definition. UNIT V . concept of del factor and its use for design of batch sterilization cycles. Surface vs diffusion controlled operations. Absorption in packed columns. oxygen demands. 2. absorption in tray column. “Mass Transfer” McGraw Hill (1975). New York: McGraw-Hill. gas-liquid equilibria. dew point. Flash vaporization and Steam distillation. Adiabatic operation. 3. NTU & HETP concepts. yield and productivity concepts. Henry’s law. UNIT IV Liquid extraction: Cocurrent and countercurrent operations in single and multistage solvent extraction. Residence time concept. transfer coefficients and relative volatility. References: 1. Leaching: Co current and countercurrent operations in single and multistage leaching operation.

Hammer. B. cell recycle. Tata McGraw- Hill Publishing Company Ltd. Text Books: 1. . Operation and design features of sedimentation tanks. “Water supply and Pollution control”. UNIT V Anaerobic digestion. Types of activated sludge process. Pergamon Press. Inc. Millis. Oxidation. Primary. Metabolic pathway synthesis of small molecules.Ideal continuous stirred tank fermenter: material balance. Harper & Row Publishers. McGraw-Hill Book Co. mechanism of anaerobic digestion.E. Composting. “Principle of Fermentation Technology”. Removal of nitrogen and phosphorous. ozone. key crossroads and branch points in metabolism. UV light UNIT IV Theory of activated sludge process. Howard & Peavy. Kristiansen. Ion exchange UNIT III Bioprocess kinetics applied to waste treatment.F. lipids. etc. distilling and brewing. Chemical treatment: pH adjustment. anaerobic treatment systems. advantages of multiple fermenters in series. Warren Viessman Jr. antibiotics. operation and control. UASB. University of Tokyo Press. TBE502: Waste Water Treatment L T P 2 0 0 UNIT I Introduction. New Delhi. New York. Humphrey. “Basic Biotechnology”. Whitaker. chlorine dioxide. Text Books: 1. “Environmental Engineering”. Shuichi Aiba. 2. New developments as fixed film reactors. 2. modifications. Donald R. Septic and Imhoff tanks. secondry and advanced treatment methods UNIT II Physical treatment: Screening. Disinfection with Chlorine. “Waste Water Treatment”. Rawe and George Tehobanoglousd. References: 1. Physical. 3. digester design. “Biochemical Engineering”. Case studies for treatment of industrial wastes e. Ollis. Bu’lock. design. high rate digestion. Academic Press. Definition. sugar and treatment of hazardous waste etc. Metcalf & Eddy. Mcgraw-Hill International Editions. Nancy F.. TBE503: Bioprocess Principles L T P 2 0 0 UNIT I Coordination of microbial metabolism with reference to carbohydrates. concept of wash out. References: 1. P. proteins. “Waste Water Engineering: Treatment. sources and types of wastes. and Mark J. J. Arthur E. Bailey and D. “Biochemical Engineering Fundamentals” by J. Rao & Dutta. chemical and biological characteristics of waste water. Operation and design features of trickling filters and rotating biological contractor (RBC).F.. Disposal and Reuse”. 3. Stanbury and A.g.

elemental material balance for growth. dextran and other biopolymers as PGA. Second Edition. metabolic engineering and protein formulation development. A. New York. 2. UNIT IV End-products of metabolism: Primary and secondary metabolites. Vol. Bailey and D.H. properties. Biotransformations – drug metabolism and xenobiotics. merits and demerits classification. TBE504: Fermentation Biotechnology – II L T P 2 0 0 UNIT I Antibiotics: general properties and classification. production. “Microbial Technology”. streptomycin. Anaerobic metabolic end products. Whitaker. solvents. Production of Penicillin. heat generation. References: . Phase – I and Phase – II reactions. control of metabolic pathway by regulatory enzymes. “Biochemistry”. merits and demerits. mode of action and their production. 2. etc. organic acids. Text Books: 1. Academic Press. PLA. UNIT II Vaccines: types of vaccines. Lehninger. Overall growth stoichiometry. tetracycline and erythromycin. CBS Publishers and Distributors. Interferon: classification. L. Ollis. their mechanism and production strategies. . yield concepts. W. amino acids. H. Microbial biotransformation. Biosurfactants: classification. PHB. Allosteric enzymes. References: 1. J. UNIT IV Bioploymers: production. Perlman. Text Books: 1.J. such as enzymes. UNIT V Stoichiometry of cell growth and product formation. Lubert Stryer. Regulation of a few major metabolic pathways. Principles of Fermentation Technology. characteristics.E. “Biochemical Engineering Fundamentals”. Peppler and D. Control of protein synthesis by induction and repression. New York.F.UNIT II Regulation of the synthesis of enzymes. Freemen & Co. Hall.II. UNIT III Biofertilizers and Bioinsecticides. P F STANBURY. UNIT V Recombinant derived products and applications: rDNA technology overview. biodegradation. “Principles of Biotechnology”. mode of action and their production. hormones: classification. A. UNIT III Basic enzyme kinetics and inhibition kinetics. S. McGraw-Hill Book Co. nucleotides and antibiotics. mode of action and their production.

10. Casida Jr. Studies on sedimentation and filtration. Inc. Turbidity (NTU).G. Studies on Heat Exchangers viz. Studies on Absorption/ Humidification/ Dehumidification columns. 5. Pressure Drop studies in pipe fittings 4. Analysis of' finished products (rectified sprit. Screen Analysis 3. Concentric pipe heat exchanger. Microbiological examination: Total Coliform test. New York. Estimation of dissolved oxygen in water sample.C. McGraw-Hill Book Company. Studies on Rotameter.1. Determination of Chemical Oxygen Demand (COD) in wastewater sample. Crushing Rolls 2. Shell and tube heat exchanger. 9. fixed and total. Determination of fermentation efficiency of yeast for batch production of ethanol. Dunn. Fecal coliform test. 3. 10.Temperature. Venturi meter and V – Notch. Escherichia coli test in drinking water and waste water. 3. 3. nitrate and Nitrite in water samples. Orifice meter. Wiley Eastern Ltd. 7. Studies on Jaw Crushers. Effect of substrate concentration on biomass yield for baker's yeast production and its characterization. Studies on Single effect/ Multiple effect evaporators. 6. 2. “Industrial Microbiology”. Preparation of malt and determination of diastatic power. Microbial production of enzymes by (a) solid state and (b) submerged fermentation. Analysis of molasses. beer etc. 7. Total phosphate test in polluted and non polluted water. 6. 7. Evaluation of physical Parameters of Waste water . Hammer mill. 4. pH . Studies on extraction column. L. 2. PBE502: Waste Water Analysis Lab L T P 0 0 3 1. . Estimation of total nitrogen. 2.). Brian McNeil & Linda Harvey (Editors). Ball Mill. Determination of Solids: Volatile. Studies on Bubble cap/ tray/ fractional column. Estimation of inorganic ions in water. variables on the performance of activated sludge process. 8. 5. S. Citric acid production by (a) solid state and (b) submerged fermentation. 4. Wiley Eastern Ltd. 8. 8. 9. 5. PBE501: Fermentation Lab L T P 0 0 3 1. Determination of Biochemical Oxygen Demand (BOD) in wastewater sample. Laboratory Courses PCH505: Chemical Engineering Operations Lab L T P 0 0 2 1. Prescott and C.E. Evaluation of the effect of process. 6. “Industrial Microbiology”. ‘Practical Fermentation’. Fermentation efficiency for vinegar production.

organizing. Management by objective. and Wallace Stettinius. Behavioral approach. change management and stress management and their importance in societal development. Tata McGraw Hill. types of business environment. Modern and contingency approach. UNIT IV Modern concepts in management: Time management. profession and administration.TECH. 12. administrative thought and bureaucracy management thought).. 7th Ed. Robert D. Hardie. Dubrin. Essentials of Management (7th Edition) by Andrew J. UNIT III Functional areas of management process: Planning. Text Books: 1. 2007. Essentials Of Management. Concept of leadership and its importance. Decision making and Motivation: Concept and importance. George W. leading and controlling. 7th Edition 3. Essentials Of Management by Harold Koontz. solving case study. science. Colley.Koontz H. yale university press. internal and external environment. Industry visit for practical exposure of management. staffing. John L. 475 Pages. Presentations and role play. case studies. Principles of General Management. Published 2005. Evaluation of performance of anaerobic digester. corporate social responsibility (CSR). importance of CSR in industry. What is business plan and importance of effective business plan. Published 2006 by Tata McGraw- 4. mean. Management as an art. Heinz Weihrich. Nature. Jacqueline L. UNIT V Business Environment: Concept. UNIT II Principles of management: Early classical approach (theory of scientific management thought. Case methods. Logan.11.. Doyle. and Weihrich H. Levels of management.. characteristics and significance of management. importance. TBE601: Bioprocess Engineering – II L T P 3 1 0 . Characterization of domestic and industrial waste water B. 2007 2. Jr. Difference between management and administration. Social responsibilities of management. Role of management in industry and business. 3rd Year (Biochemical Engineering Branch) 6th Semester Theory courses THU601: Principles of Management L T P 2 1 0 UNIT I Introduction to Management: Mean.

L. UNIT III Packed and fluidized bed reactors: Analysis and application. Use of Laplace & Inverse Laplace Transformation is study of Process Dynamics. applications and its limitations. Dynamic behavior of second & higher order system for various kind of inputs. “Principle of Fermentation Technology”. flow. New Delhi. UNIT V . Pergamon Press. “Comprehensive Biotechnology”. Linearization of nonlinear system. UNIT II Principle of operation. Block & Signal Flow Diagram. Regulator & Servo control. Prentice Hall Pvt. Whitaker. P. foam control. Vol. “Biochemical Engineering Fundamentals” by J. Immobilization of enzymes and cells. liquid level. Indicating and recording type of instruments. NADH).. UNIT II Bioreactor operation measurement and control: Aseptic operations. UNIT V Scale-up: Basic concepts and related problems. Murray-Moo-Young. Dynamic behavior of First order systems and First order systems in series.E.. McGraw-Hill Book Co.UNIT I Continuous fermentation: Kinetic analysis. variables & Physical Elements of a Control system.F. comparison with batch fermentations. 2004 Reference: 1. UNIT III Introduction to Process control systems. static and dynamic characteristics of measuring instruments. Feb batch fermentation: Principle and applications Text Books: 1. Feed Forward & Feed backward control. temperature. 2. 3. measurement and control of process variables (pH. Pergamon Press. New York. pH and composition. On-line analysis and computer control of fermentation process. Fikret Kargi.F. 2. Bailey and D. Negative & Positive Feedback Control. M. Ltd. UNIT IV Non-mechanically agitated bioreactors such as airlift and bubble column. viscosity. New York. Physical.. construction and application of important industrial instruments for the measurement of temperature. agitative power. Stanbury and A. functions and general classifications of measuring instruments. Bioprocess Engineering-Basic Concepts” Shuler. Transportation & Transfer Lag. dissolved oxygen. DO. . UNIT IV Dynamic Modeling of a Process. 2nd Edition. Ollis. Elements of measuring instruments. TCH606: Instrumentation & Process Control L T P 3 1 0 UNIT I Elements of measurement . Methods of immobilization.

External and internal diffusional characteristics of immobilized systems. Fogler. O. “Chemical Reaction Engineering”. rate equations for simple and complex reactions. Heterogeneous catalytic reactions. McGraw-Hill. space velocity and residence time in flow reactors. The effect of physical properties on catalyst activity. 4th ed. semi-batch. Size comparison of single reactors like batch. 3rd ed. principles. Reactor designs for homogeneous. TCH607: Chemical Reaction Engineering L T P 3 1 0 UNIT I Chemical Reactions: Rate of chemical reactions. irreversible reaction. “Chemical Engineering Kinetics“.R. activity and the factors which influence it. Isothermal as well as non-isothermal operation. Peter Harriot. plug flow and CSIR for first and second order single reactions. kinetics of solid catalysed fluid reactions. reaction rate constant.S. TCH608: Mass Transfer Operations – II L T P 2 0 0 . H. Process Control. auto catalytic reactions and homogeneous catalytic reactions. absolute reaction rates. Text Books: 1. Coughanoowr. Prentic Hall India Ltd. Staphno polies. batch. Tata McGraw Hill. elementary and non-elementary reaction mechanism. “Elements of Chemical Reaction Engineering”. parallel reactions. Reduction of Block & Signal Flow Diagrams. D. Smith. variable affecting the reaction rate. McGraw Hill Publication. Interpretation of reactor data in constant volume and variable volume batch reactions. predictability of reaction rate. consecutive reactions. Arrhenius equation. carrier life and cycle time. Process system Analysis & Control. Controllers & Final control Elements. UNIT III Classification of chemical reactions. Levenspiel.(1990). New York John Wiley (1998) References: 1. Process control. order of reaction. rate- controlling steps. Plug flow reactions in series and for parallel equal sized CSTR’s in series. Closed loop transfer function and response of closed loop control system for various type of control actions. absorption isotherms. methods of determination of their physical properties. Reference Books : 1. UNIT V Biocatalysis: Kinetics of the immobilized enzymes. UNIT IV Catalysts: Preparation. Multiple reactor systems. plug flow and continuous stirred tank. Prentice Hall 2. 3rd edition. J. 2. Enzymes reactor performance.Modes of control action. catalyst poisoning. UNIT II Kinetics of homogeneous chemical reactions. Text books: 1. integral and differential method of kinetic data analysis. operational strategies.

and other enzymes. “Principles of Unit Operations” John Wiley (1980). PHI TBE602: Genetic Engineering L T P 3 1 0 UNIT I Introduction and historical background. diffusion coefficient. Vapour liquid equilibrium and enthalpy for a pure substance. 2. cDNA synthesis. “Mass Transfer” McGraw Hill (1975). Dehumidification and water cooling. construction of genomic library. Classification and design of crystallizers. heat and mass transfer rates in crystallization. Foust A. Mechanism of crystallization process. Treybal. adiabatic and non-adiabatic operation. L. Mass transfer theories. UNIT III Humidification and Dehumidification. Knudsen and surface diffusion. vapour pressure – temperature curve. theories of crystallization. New York: McGraw-Hill. R “Mass Transfer Operations”. wet bulb temperature. Diffusion in multicomponent gas mixtures.. Sherwood T. Equilibrium yield of crystallization. construction of vectors  Cosmids. rate of batch drying. co-current. vapour gas mixtures. K. crystal geometry. YAC. 4. Cloning vectors:  Plasmids: structural and functional organization. Scope of genetic engineering.al. evaporative cooling. UNIT IV Drying. Text Books: 1. mechanism of batch drying. Pigford R. “Principles of Mass Transfer and Separation Process”. Characteristics of adsorbent and commercial Application. continuous drying. definitions of moisture contents. McCabe Smith. construction of cDNA library UNIT III . phagemids. bonding between adsorbate and adsorbent Adsorption equilibria and isotherm. UNIT V Crystallization. Solid-gas equilibria. Supersaturation. 3. McGraw Hill. PAC UNIT II Enzymes used in molecular cloning: restriction enzymes. multistage continuous contact operations.UNIT I Diffusion: Molecular and turbulent diffusion . Diffusion in solids: Molecular. UNIT II Gas adsorption: Affinity of solid surface. invariant crystal. (1980). Binay K Dutta. fundamental concept of humidification. time of drying. Langmuir and Frendlich Isotherm. definition and derivations of relationships related with humidity. Counter-current. types of batch and continuous dryers. classification and design of cooling towers. 3rd ed. S. Fick’s law of diffusion. “Unit Operations in Chemical Engineering”. BAC. construction of pBR322  Phages: Biology of bacteriophages. ligases.. References: 1. measurement and estimation of diffusivity.. et. Mass transfer in fluidized beds.

6. Wiley-blackwell References: 1. Melnopark. Meerut. Benjamin Lewis (2000) John Wiley & Sons. 3. gene sequencing (Maxam and Gilbert. 5. “Genetics”. Transformation of the bacterial cell. 5. Growth kinetic studies of yeast in a bench top lab fermentor under controlled conditions. Determination of volumetric oxygen transfer coefficient (KL a). pyrosequencing). chromosome walking. New York. 8th Ed. Isolation of RNA by Orcinol method. plants for phytoremediation UNIT V Concept of PCR and RT PCR. Human genome project. 4. 2. effect of aeration and agitation speed etc. 7. “Recombinant DNA Technology”. Determination of specific thermal death rate constant (Kd) and activation energy for microbial strains. Sangers. Gene cloning. λ-max of nuceic acid 2. Plants with improved shelf life and improved nutrition. Determination of kinetic parameters for batch cultivation of yeast under stationary and shake flask conditions. Gene therapy.D. Identification of rDNA clones UNIT IV Identification of rDNA clones. John Wiley & Sons. “Genes”. SB Primrose. Studies on settling characteristics of various microbial cultures. PBE602: Genetic Engineering Lab L T P 0 0 3 1. Comparison of filtration efficiency of fibrous and PVA air filter. Dhillon J.K. by dinitrophenyleamine methods.. Laboratory Courses PBE601: Bioprocess Engineering Lab L T P 0 0 3 1. 7. DNA fingerprinting. Development of transgenic plants: Herbicide and pathogen resistant plants. RNAi. 6. Estimation of Tm in given sample of DNA. Enzyme concentration by ultrafiltration. P. 2. Gupta. New York. 4. Rastogi Publication. Watson. 4. Isolation of the plasmid from the bacterial sample. antisense RNA technology. gene transfer methods in plants (Direct delivery and Agrobacterium mediated ). 3.expression of genes.. 3. “Molecular Biology of the Gene”. California.R. Isolation of the DNA. Stem cell technology Text Books: 1. J. Preparation of immobilized enzymes & cells and evaluation of kinetic parameters. 8. PAGE electrophoresis of the given sample of DNA . “Principles of Gene Manipulation” Bob Old.

SNPs. Induction and repression of -galactosidase in yeast B. Drug design Approaches: Ligand based and Target based drug design. Text books: 1. Gene prediction. BLAST. Bioinformatics : Principles and applications by Ghosh and Mallick (oxford) university press) 2. Data retrieval with ENTREZ. BLOSUM) UNIT III Phylogentic Analysis. Central Dogma of Molecular Biology. TFB Sites. Sequence alignment algorithm (FASTA.8. Drug discovery Pipeline. CHIME etc. Protein Structure alignment and analysis. BLOCK (Secondary databases). Sequence based prediction methods. UNIT IV Protein structure prediction: Secondary and tertiary structures. Profiles. Annotation and Analyzing whole Genome sequences. FASTA and PSI BLAST). Major Databases in Bioinformatics. gene expression. PROSITE. Computer added drug designing.). Chou Fasman method. Smith Waterman). parish and Tweman (Bios scientific publishers) . 4th Year (Biochemical Engineering Branch) 7th Semester Theory courses TBE 701: Bioinformatics L T P 3 1 0 UNIT I Definition and application of Bioinformatics. Database similarity searches (BLAST. Functional Genomics. Instant notes in Bioinformatics by Westhead. GOR method. Genome sequencing and Sequence Assembly tools. Hidden Markov Model (HMM) and its Application. UNIT V Structure visualization methods (RASMOL. Pfam. Amino acid substitution matrices (PAM.TECH. SRS. global and local). Specialized sequence databases of EST. ORF prediction. Patterns and motifs. Needleman and Wunsch. Microarray data analysis. Primary and secondary databases. DBGET UNIT II Sequence alignment (pairwise and multiple. ab initio prediction.

John Wiley & Sons. Patent laws. Fourth Eye (Excellence through Creativity). brain storming. GMP UNIT V Laboratory Creative design . Managing technological innovation. International code for patents . 1992. 2. krane Reference books: 1. Innovation and Product Development L T P 3 1 0 UNIT I Introduction and Creativity The process of technological innovation. Harry Nystrom. marketing research .introducing new products.patent search. Prentice-Hall Inc. 1997.P.Selection criteria . N. 3. creativity ‘and problem solving. Text Books 1. 2.Testing – cost – evaluation. The need for creativity and innovation. Creativity and innovation. Introduction to bioinformatics by Attwood and Parry Smith (Pierson education Publication) 2.screening ideas for new products (evaluation techniques). TIFAC.R.quality standards.different techniques. UNIT III New Product Development and Patent Laws Research and new product development Patents . References 1. Harry B. Brain Twiss. Bulletins. 1992. Pitman Publishing Ltd. New Delhi.Intellectual property rights (IPR).. factors contributing to successful technological innovation. I. 1992. P. New Product Planning.testing . UNIT II Project Selection and Evaluation Collection of ideas and purpose of project. Khandwalla. 1979.Model Preparation . Allahabad. Wheeler Publishing. Fundamental concept of bioinformatics by Dan e.GLP. UNIT IV New Product Planning I Design of proto type . Watton. Bioinformatics by Andreas D Boxevanis (Wiley Interscience) Professional Electives (PE-I) TBE011: Enzyme Engineering L T P 3 1 0 TBE012: Creativity. TBE013: Modelling and Simulation of Bioprocesses L T P 3 1 0 UNIT I .3. Patent application.

Roels “ Application of simple structured I Bioengineering. Microbes and Minerals.Mechanism of drug action. References: 1. Sources of Drugs . Different dosage forms. Fiechts (ed) Spring –Verlag . Equation oriented simulators (SPEED UP. UNIT IV Process simulation techniques. 1982. factors that affect the absortion of drugs.Drug absortion. sources of Biopharmaceuticals. Routes of drug administration. Modelling for activated sludge process. A. Bailey and D. Models for lactic acid fermentation and antibiotic production. UNIT II Pharmacodynamics Physico-Chemical Principles. Shu’s segregated models for Lactic acid fermentation. Unstructured and structured models.F. Equation oriented approach. Simulation of biochemical system models. Production of Therapeutic Proteins. Product formation. 2. QUASILIN. DYNSIM). Haerder and J.E. Biomaterials and Their Applications . UNIT III Pharmacokinetics Pharmacokinetics. Berlin. Ollis. Modelling and Simulation. UNIT IV Drug Manufacturing Processes and Production of Biopharmaceuticals Good manufacturing practices. Interleukins I & II. UNIT II Structured kinetic models: Compartmental models (two and three). Newton – Raphsen methods.Approach to modeling.Plant. A. Hormones. Runga – Kutta methods. 1986.Interferons. Francis. Text Books: 1. UNIT V Drug Delivery Systems. UNIT V Simulation programs based on Euler’s methods. Pharmacodynamics. Cytokines . manufacturing facilities. Tumor Necrosis Factor (TNF). ASCEND. and Physiological receptors: structural and functional families. McGraw Hill Book Company TBE 014: Biopharmaceutical Technology L T P 3 1 0 UNIT I Introduction to Pharmaceuticals History & Definition of Drugs. Biotransformation of drugs. Segregated and unsegregated models. and P55 in Advances In Biochemical engineering Vol21. Production & analysis of Biopharmaceuticals. drug receptors. Model for anaerobic digestion. Nucleic acids. Genetically structured models. G. J. Bioavailability of drugs. Distribution of drugs. UNIT III Stochastic model for thermal sterilization of the medium. FLOWSIM. Animals. Unstructured and structured modeling. Deterministic and stochastic models. Biochemical Engg Fundamentals.

introduction and Bioethical issues in Biotechnology Text Books: 1. Biomaterial for the sustained drug delivery. Budapest treaty. Risk assessment of Biotechnology Product. in situ polymerization UNIT II Biologically Derived Biomaterials and Fermentative Production . UNIT IV Detailed information on patenting biological products. John Wiley & Sons Ltd. Appropriate case studies.like patent. major changes in Indian patent system as post TRIPS effects (i) obtaining patent (ii) geographical indiation. Biodiversity. Intellectual Property Protection & Sustainable Development. 2. duties and their correlation. Biosafety & IPR L T P 3 1 0 UNIT I Jurisprudential definition and concept of property. Biotechnology & Safety Assessment. UNIT II Distinction among various forms of IPR.) Leon Lachman. Ldexix Nexis Butterworths. invention step and prior art and state of art. 1980. TBE022: Biomaterial Science and Technology L T P 3 1 0 UNIT I Introduction and Selection of Biomaterials Definition of polymers and biomaterials. remedies against infringement – civil and criminal. Gary Walsh. Selection criteria. procedure UNIT III Rights/protection. Mark Publications & Company eston PA. Biosafety Guidelines in India. Theory & Practice of Industrial Pharmacy. functionality. Biopharmaceuticals: Biochemistry & Biotechnology. History and evolution of IPR. Ane/Rout Publishers. Indian patent act 1970 (amendment 2000). polymer isomerism. Liposome mediated drug delivery. Risk assessment for Planned introduction. rights. 2. UNIT V Biosafety. design and copy right. Drug delivery methods for therapeutic proteins. Role of Biopharmaceuticals in treatment of various health disorders Text Books 1. Requirement of a patentable novelty. Thomas. Lea & Febiger (1986) (PE-II) TBE021: Bioethics. (1998). Phillipe Cullet.Controlled and sustained delivery of drugs. Biosafety level. Remington’s Pharmaceutical sciences. Risk Regulation. membrane lamination. Risk Assessment. infringement or violation. (3rd ed. fiber folding. Reference: 1.

synthesis in organism and extraction. Electrophorosis. D. UNIT V Membrane Preparation and Membrane Modules: Isotropic Membranes. Plenum Pulo. Anisotropic Membranes. 1991. TBE023: Advanced Bioseparation Processes L T P 3 1 0 UNIT I Historical Development and introduction of Membranes. microbial cellulose. Zone melting. pH and heatless parametric pumping.B. Membrane Modules. Classification. UNIT IV Cryogenic separation. Economics of Membrane operations. UNIT II Reverse osmosis. Boundary Layer Film Model. Biomaterials –novel materials from biological sources. Text Book: . Concentration Polarization in Liquid and Gas Separation Processes. use of reactors. Structure Permeability Relationship in Solution diffusion. Pore flow Model. micro-filtration. UNIT III Foam and bubble separation: Principle. References: 1. kinetic analysis for production. Column operations. Membrane modules and application. 1984. polymer coated blood. Biopolyester. separation of Biomaterials by cell digestion and extraction Text Books: 1. Hollow Fiber Membranes. microbial polysaccharides. Pressure and temperature swing adsorption. Cross-flow. polymer precursor synthesis and characterization UNIT V Optimization of Production Kinetics. Multicomponent separation. nano-filtration. Determination of the Peclet Number. Separation techniques. Analysis and modeling of membrane separation processes. J. Ultra Filtration and dialysis. bioadhesive. Metal Membranes and Ceramic Membranes.Polyhydroxialkanoates. Liquid Membranes. zone refining and zone leveling. Liquid membranes and its industrial applications. Co-flow and Counter-flow. Super. Solution diffusion Model. polyglutamic acid UNIT III Materials for Tissue Engineering and Improved Functions of Biopolymers Case studies with regenerated polymers.characterization.critical extraction. Thermal. polylactides. Parametric pumping: Batch. Biomaterials science and engineering. Ion selective membranes and their application in electro-dialysis. Stockton press.Park. Byrom. Pervaporation and gas separation using membranes. Separation Statistical optimization of probable variables for production of biomaterials. 2. New York. A. Steinbuechel – Biopolymers. Genetic and molecular Biology aspects of synthesis UNIT IV Trends in Biocomposite Biodiode. Types of Membranes and Membrane Processes Membrane Transport Theory: Introduction. continuous and semi- continuous pumping.

H2. Methanogenesis: methanogenic. water. Aluminium. TBE 024: Solid State Fermentation L T P 3 1 0 (PE-III) TBE031: Environmental Biotechnology L T P 3 1 0 UNIT I Environmental pollution: Land. cellulases and food and feed stocks. Waste Water Engineering. Principles and design aspects of various waste treatments methods. D. 1972. and Henley E. C. Seader. 3.J. Economical and social aspects of waste treatment. Bioenergy. 5. “Separation Process Principles”. Lacey. "New Chemical Engineering Separation Techniques". John Wiley & Sons. . C. 2nd ed. and noise (introduction. Biopesticides.Nitrate and sulfite biosensors UNIT II Biological waste treatments. effects and measurements). trickling filter. Wiley Publications 3. New York. and fermentative bacteria – anaerobic and aerobic digestion processes and conditions. Ecology & Environment.. Reference 2.. heavy metals and nitrogenous wastes.P. John Wiley & Sons Inc. acetogenic. Inc. biogas. Inc.1. air. J. 2..Dwivedi & Mishra. Introduction to Waste Water Treatment. 2007. Winter. sequential batch reactor. Loeb and R. Minimal national standards for waste disposal. Bhattacharya & Ritu Banerjee. UNIT IV Conservation of biodiversity. Environmental Biotechnology. Biofertilizers. B. Oxford Press. fixed / packed bed reactor. Richard W. Wiley Inter Science. upflow anaerobic sludge blanket reactor. 3rd ed. sources. biomass production. S. Environmental Processes I-III. 4. Text Books: 1. Inter Science Publications. Academic Press. 1972. hybrid reactor. Ed. “Separation Processes”. Germplasm conservation. biofuels.C. Ramalho. McGraw-Hill. water. Biodegradable plastics UNIT V Bioremediation: land.D. Schoen. Biosensors to detect environmental pollution: BOD. industries. References: 1. UNIT III Bioreactor configuration: activated sludge process. J. Environmental Studies. M. King. Membrane Technology and Applications. H. Baker. 2007. "Industrial Processing with Membranes". contact process. fluidized bed reactor. 2. organic contaminants. 4. Sharma. 8th ed. E.Metcalf & Fuddy.J.R.

New Age International Publishers. function and application of cytokines. International Pvt. T &B cell maturation. D. Rana. precipitation reactions. Chakravarty (Oxford University Press) 4. Ane/Rout Publishers. S. Perspectives in Environmental Studies. UNIT II Characteristics and types of Antigens. Singh. Pubishers TBE032: Immunology L T P 3 1 0 UNIT I Introduction to immunity. UNIT III Structure and Function of MHC molecules. UNIT IV Antigen and antibody interactions. Environmental Biotech.V. Factors affecting the immunogenicity. Humoral and Cell mediated immune response. Wise. Antigenic Determinants on Immunoglobulins. RIA and western blotting Production and application of monoclonal antibodies. Cancer. Essentials of immunology by Roitt (Blackwell scientific publication) 2. Prentic-Hall India. functions and characteristics of different classes of antibodies. 2004. Exogenous and Endogenous pathways of antigen processing and presentation. UNIT V Immunity against infectious diseases (virus. Epitopes.P. ABO blood group antigens. 10. Ane/Rout Publishers. Immunology by Kuby (Free man publication) Reference books: 1. Environmental Microbiology & Biotechnology.K. Fatima TBE033: Preservation of Biomaterials L T P 3 1 0 . Haptens and adjuvants. Hyper-sensitivity. AIDS and Transplantation immunology. Industrial & Environmental Biootechnology. 9. bacteria and protozoan). 2006. Elsevier Ex. 11. Olguin. New Age International Publishers. immune tolerance. Anubha Kaushik & C P Kaushik.. Inflammation. S. I. Characteristics of innate and adaptive immunity. serological techniques – ELISA. Structure. regulation of immune response. Primary and Secondary lymphoid organs. Immunology and immunotechnology by Ashim k.S.. Environmental Biotechnology & Cleaner Bioprocesses. Complement system. dose of antigens. Autoimmunity. Pradipta Krimar. Dwivedi. Structure. 8.6. Text books: 1. Vaccines. Characteristics of T&B cell epitopes. Global Environmental Biotechnology. Ahmed. activation and differentiation. Immunology by C. 2006. Cells and Molecules of the immune system. 7. Immunology by Benacera 3. Essentials of Ecology & Environmental Science. Hematopoiesis.K. 12. 2004. Ltd. cross reactivity.

VI Publications. UNIT II Application in Biomedical and biological research. nano chemicals and application. 3. UNIT V Chemical preservatives.N. macro molecular assemblies. Atomic force microscopy.their uses in pharmaceutical. References: 1. “Principles of Food Preservation” by V. Food spoilage and poisoning. UNIT III Developing drug delivery tools through nanobiotechnology. their properties and function. UNIT III Unit operations in food processing. biological production of metal nano-particles. 2. safety and quality control. viruses as nano-particles. “Food Science” by N. UNIT II Chemical constituents of food/Biomaterials. Principles of food preservation: High and low temperatures. Part-II: Physical Methods of Food Preservation by M. nano-particles. UNIT IV Synthesis and characterization of different classes of biomedical polymers. TBE 034: Secondary Metabolites L T P 3 1 0 Open Elective TBE061: Nanobiotechnology L T P 3 1 0 UNIT I Basic biology principles and practice of micro fabrication techniques. “Principles of Food Science”. UNIT IV Drying and dehydration. Jay. tumor targeting and other diagnostic applications. immuno-nanotechnology Text Books: . quantum dots technology and its application. “Modern Food Microbiology” by James M. nano-particle based immobilization assays. Text books: 1. UNIT V Biosensors and nanobiotechnology principles used in construction of micro electronic devices sensors and macro mechanical structures and their functioning. Characteristic features of natural and processed foods. Karel. cardiovascular ophthalmologic orthopedic areas. Elsevier Press.UNIT I Preservation and maintenance of microbial cultures. Potter. Legislation. radiation and osmotic pressure. Kyzlink.

John Willey & Sons. An Overview of Performance and Applications. Principles of Chemical Sensors. fluorescence. C. Schellr. References: 1. Alice Cunningham. Text Books: 1. References: 1. UNIT III Biorecognition systems: Enzymes. Affinity-based biosensors.. Biosensor Engineering: Methods for biosensors fabrication: self-assembled monolayers. Implantable sensors for long-term monitoring. Peptide immobilization. niemeyer. Birkhauser Verlag. selectivity. Editors: F. Forensic science benefits. Drug development and detection. Plenum Press. Graham Ramsay Editor. Fedrowitz. Application: Clinical chemistry. John Wiley& Sons. MEMS. Brian Eggins. 1995. Cell culture. Cell immobilization. Biochips and biosensor arrays. sensitivity. Ligler. Oligonucleotides and Nucleic Acid immobilization. Lipids (Langmuir-Blodgett bilayers. microcontact printing. ENFET). Rowe Taitt. Problems and trade- offs. bi-enzyme electrodes: enzyme sequence electrodes and enzyme competition electrodes. 2. Thermal transducers.concepts. UNIT II Physico-chemical transducers: Electrochemical transducers (amperometric. Inhibition. Cell-based biosensors. Edited by: F. conductimetric). TBE062: Biosensors L T P 3 1 0 UNIT I General principles: A historical perspective. 2002. Mirkin. Main technical definitions: calibration. Problems and limitations. Frontiers in Biosensors. 3. Optical transducers (absorption. SPR). Present & Future. Liposomes). reproducibility. potentiometric. Engineering concepts for mass production. Optical Biosensors. Antibody immobilization. Urea determination. UNIT V Biosensors: Catalytic biosensors: mono-enzyme electrodes. John Wiley& Sons. Limitations & problems. J. Microbial metabolism. 2002. Nanobiotechnology of biomimetic membranes. Jiri Janata. screen printing. donald (edt). Food quality control. Signal transduction. Problems & limitations. Sensor types and technologies. Limitations & problems to be addressed. Chemoreceptors. Commercial Biosensors. Schubert.based biosensors. Tissue and organelles (animal and plant tissue). Immunoreceptors. UNIT IV Immobilization: Enzyme immobilization. Chemical Sensors and Biosensors. applications and perspectives. 1998. springer verlag publishers. Definitions and Concepts: Terminology and working vocabulary. 1989. Semiconductor transducers (ISFET. Test-strips for glucose monitoring.1. photolithography. F. Piezoelectric and acoustic-wave transducers. response time. martin. 5. Phospholipids. 4. Introduction to Bioanalytical Sensors. Membrane receptors and transporters. chad a. 1998. Environmental monitoring. Physico-chemical and biological transducers. Oligonucleotides and Nucleic Acids. detection limits. Christ of m. . Nanobiotechnology. bio/chemiluminescence. Elsevier. Technological process control. wiley publishers.

Singh. Ursula Spichiger-Keller. water. 1998. 11.. Olguin. 5. 8th ed. 2004. Bhattacharya & Ritu Banerjee.V. Pradipta Krimar. 4. Chemical Sensors and Biosensors for Medical and Biological Applications. sources. Oxford Press. contact process. 8. Environmental Biotech. 2007. Waste Water Engineering. 7. organic contaminants. International Pvt. UNIT III Bioreactor configuration: activated sludge process. New Age International Publishers. and noise (introduction. H2. 6. Biofertilizers. Text Books: 1. B. J. biomass production. trickling filter. water. biofuels. Wiley Publications 3.P. Germplasm conservation. hybrid reactor. Ane/Rout Publishers. Economical and social aspects of waste treatment. upflow anaerobic sludge blanket reactor. Biosensors to detect environmental pollution:BOD. Environmental Biotechnology. acetogenic. Aluminium. fluidized bed reactor. Prentic-Hall India. Wise. Pubishers TBE064: Bioinformatics L T P 3 1 0 . Principles and design aspects of various waste treatments methods. S. 9. Dwivedi.R. New Age International Publishers.6.Dwivedi & Mishra. Elsevier Ex. Global Environmental Biotechnology. 3rd ed. cellulases and food and feed stocks. 2nd ed.K.. Winter. Introduction to Waste Water Treatment. Environmental Microbiology & Biotechnology.K. Bioenergy. 12. 2007. 10. Sharma. S. Ane/Rout Publishers. Environmental Studies. air.P.. 2006. Academic Press.Nitrate and sulfite biosensors UNIT II Biological waste treatments. Environmental Processes I-III. Industrial & Environmental Biootechnology. industries. UNIT IV Conservation of biodiversity. effects and measurements). 2. Ed. 2006. Rana. Methanogenesis: methanogenic. sequential batch reactor. References: 1.Metcalf & Fuddy. heavy metals and nitrogenous wastes. S. Ahmed. biogas. Biodegradable plastics UNIT V Bioremediation: land. Essentials of Ecology & Environmental Science. Environmental Biotechnology & Cleaner Bioprocesses. Anubha Kaushik & C P Kaushik. and fermentative bacteria – anaerobic and aerobic digestion processes and conditions. Perspectives in Environmental Studies. fixed / packed bed reactor. 2004. Wiley-VCH.C. D.S. Biopesticides. Ltd. Ramalho. I. D. TBE063: Environmental Biotechnology L T P 3 1 0 UNIT I Environmental pollution: Land. Ecology & Environment. Minimal national standards for waste disposal.

CHIME etc. protein structure and function. BLOCK( Secondary databases). Sequence alignment algorithm (FASTA. Specialized sequence databases of EST. In this semester he/she will be assessed (out of 50 marks) for the work that he/she does during the seventh semester under the supervision of a faculty of the department. DBGET UNIT III Sequence alignment (pairwise and multiple. parish and Tweman (Bios scientific publishers) Laboratory Courses PBE701: Project-I L T P 0 0 6 The student would be allotted a project in the beginning of the VII semester itself. Pfam. Group discussion will be organized to develop skill of presentation. Amino acid substitution matrices (PAM. Bioinformatics : Principles and applications by Ghosh and Mallick (oxford) university press) 2. Data retrieval with ENTREZ. Smith Waterman). Gene structure and Information content. Bioinformatics by Andreas D Boxevanis (Wiley Interscience) 3. He/She would be expected to submit a detailed plant design report later in the (VIII) semester. PBE702: Summer Training Report Evaluation & Viva L T P 0 0 2 Each student is required to deliver a seminar on pre-assigned topic. BLAST. ORF prediction. Molecular Biology tools. Text books: 1. Fundamental concept of bioinformatics by Dan e. chronological history Molecular Biology’s Central dogma. Database similarity searches (BLAST. FASTA and PSI BLAST). UNIT II Primary and secondary databases. . The project may or may not be based on the industry where he/she has undergone in plant training in industry during summer vacations. Instant notes in Bioinformatics by Westhead. organization and impromptu discussion. BLOSUM) UNIT IV Protein structure prediction (Chou Fasman Method): Secondary and tertiary structures. UNIT V Structure visualization methods (RASMOL. SNPs. PROSITE. Introduction to bioinformatics by Attwood and Parry Smith (Pierson education Publication) 2. SRS. Protein Structure alignment and analysis. gene expression. global and local). TFB Sites. Gene prediction. Homology Modelling. Profiles and motifs.UNIT I Definitions of informatics. Microarray data analysis. Application of Bioinformatics in drug discovery and drug designing.). krane Reference books: 1. Needleman and Wunsch.

material of construction. Types of taxes and insurance’s. specification and design of equipment’s. Plant location. Start up. pilot plant. . cost index. Material and energy balances. UNIT II Cost Engineering: Time value of money and equivalence. process equipment cost estimation. Scale up methods. UNIT III Cost Estimation: Types of cost estimation. estimation of plant cost. depreciation rates in current Indian situation.B.Selection of equipment. working capital cost. Depreciation. Process selection. Taxes and Insurances. fixed capital cost. Annual equivalent cost and capitalized cost methods.TECH. Nature of depreciation. Plant Design: Design basis. Plant layout and installation. Shutdown and Operating guidelines. Procedure for cost comparison after taxes. 4th Year (Biochemical Engineering Branch) 8th Semester Theory courses TBE801: Bioprocess Plant Design and Economics L T P 3 1 0 UNIT I Process Development: Process selection. start-up costs. cost comparisons by present worth. Battery limit investments. Methods of determining depreciation. Safety. study of alternative processes. Uniform gradient and series. Estimation of total product cost. capital investment cost. General expenses. Interest. Flow sheet preparation. Stream designation. sketching techniques. Equipment costs due to inflation. Equipment numbering. Manufacturing cost.

Text Books: 1. biological production of metal nano-particles. UNIT II Application in Biomedical and biological research. Aries & Newton.Profitability: Criteria of profitability. cyclic and semicyclic operation. transportation systems. Atomic force microscopy. nano-particles. Cash flow analysis. Determination of height and diameter of different process equipments at conditions of optimum cost . quantum dots technology and its application. & Ronald W. Payout period.Pinch Technology analysis. UNIT IV Synthesis and characterization of different classes of biomedical polymers. UNIT V Biosensors and nanobiotechnology principles used in construction of micro electronic devices sensors and macro mechanical structures and their functioning... immuno-nanotechnology Text Books: . Present value. heat exchangers. mass transfer equipments and reactors. Sensitive analysis in project profitability.. macro molecular assemblies. UNIT III Developing drug delivery tools through nanobiotechnology. Peters M. Process Engg.their uses in pharmaceutical. James R Couper. Return on investment. nano-particle based immobilization assays. Timmerhaus K. Cost Estimation. Linear programming and dynamic programming establishing optimum conditions. Economics (Chemical Industries) CRC Press 2. Chemical Engg. viruses as nano-particles. nano chemicals and application. Alternative investment analysis. evaporators. graphical and incremental methods of solution. Optimum production rates in plant operation. Uni-variable and multivariable systems. LaGrange multiplier method. UNIT IV Economic Optimization and Optimum Design: Nature of optimization. Sensitivity and response analysis. Plant Design & Economics for Chemical Engineers. McGraw Hill Professional Electives (PE-IV) TBE041: Nanobiotechnology L T P 3 1 0 UNIT I Basic biology principles and practice of micro fabrication techniques. Analytical. McGraw Hill References: 1. UNIT V Optimisation of Different Process Equipment: Viz. tumor targeting and other diagnostic applications. Preparation of techno- economic feasibility report. Break even chart for production schedule. cardiovascular ophthalmologic orthopedic areas. Optimum conditions in batch.

Challenges for the flavour and Food Industry. Rheology of Food Production. vitamins. Whitehurst & Maarten van Oort. A. Food Microbiology. New Delhi. Robert J. Lindsay.1. martin. Wiley . 4. yogurt. 1988. 2. Food Preservation with Low Temperature. Intrinsic and Extrinsic parameters of Foods that affect microbial growth.. Christ of m. Text Books: 1. Drying. Use of fermentation for Food preservation. and John. Gordon. Basic principles. 2009. canning. Enumeration and Detection of Food-borne Organisms. B. Bibek Ray. applications and perspectives. Role and significance of microorganisms in foods. 3. dehydration. Enzymes in fat/oil industries. Protease in cheese making and beverage production. 4th Edn. High Temperatures. and health benefits of fermented milk foods products. 2. D. Indicator and Food-borne Pathogens.. Fundamental food microbiology. Mirkin. Food Biotechnology. wiley publishers. Probiotics and prebiotics.C. donald (edt). Glucose oxidase in food Processing. T. UNIT II Food Production technology: Starter cultures. Willis Elsevier.concepts. 2007. Other Proven and Suspected Food-borne Pathogens. TBE042: Food Biotechnology L T P 3 1 0 UNIT I History of Microorganisms in food. evaporation.oxford university press. niemeyer. pasteurization and sterilization etc. Bioassay and related Methods. Microbial food additives: colour. major ingredients present in different product. Mechanism and advantages of food preservation by Lactic acid Bacteria. Single cell protein (yeast. 1987. springer verlag publishers. unit operations. Roger. chad a. CRC PRESS References: 1. mushroom and algal protein). UNIT IV Food quality and control Analysis of food. Medical foods.. Jay. Nanobiotechnology. UNIT V Food Preservation Technology Storage stability. Historical Developments. 3. References: 1. 2005. and Weshoff. Modern Food Microbiology.. Nanobiotechnology of biomimetic membranes. McGraw Hill Book Co. Essentials of human nutrition. J. Applied Science Biotechnology.. Pickling and bread making. flavour. CBS Publications. using food additives and Irradiation.M. 1988.. New York. 3rd edition . and equipment involved in the commercially important food processing methods: blanching. Enzymes in Food Technology. UNIT III Technology for improved process Enzyme in bakery and cereal products. 1989. Fermentative production of food: Cheese.. Utilization of food waste for production of valuables.S. Mann & Trusswell . W. Frazier.

identification of hazards and its estimation. classification of microbes with respect to pathogenicity. Co-ordinate systems two – matrix. use of respirators. Regulation and legislation. disaster planning and management. Sanjoy Banerjee. Bond stretch. What are models used for? Areas of application – Single molecule calculation. Miscellaneous interaction. Industrial hygiene and safety aspects related to toxicity. Introduction. hazard reduction in biochemical industries. radiation etc. Prentice Hall (1990) 2. controlling toxic chemicals and flammable materials. A. UNIT IV Prevention of losses.TBE043: Industrial Safety & Hazard Management L T P 3 1 0 UNIT I Industrial safety. John Wiley &Sons. their entry routes into human system. Applications to protein folding UNIT III .S. H. safety aspects related to site. UNIT II Molecular Mechanisms.Vander waals interactions. potential energy surface. their doses and responses. disposal rules. scope of risk assessment. 1982. Text Books: 1. plant layout. methods of containment. UNIT II Elements of safety. fault free method. process development and design stages. temperature. UNIT V Biohazards. fire and its prevention.“Industrial Hazards & Plant Safety”. transportation and storage of flammable and toxic materials. event free method.F. risk analysis and assessment methods. angle bending. Crowl and J. Constant temperature and constant dynamics. “Chemical Process Safety (Fundamentals with Applications)”. molecular size versus accuracy. risk. ventilation systems. Handling. Conformation searching. control techniques for toxic substances exposure. Wood. Fawcett and W. Explosions including dust. energy calculations. Electrostatic interaction. Approximate molecular orbital theories. Louvar. Postulates of quantum mechanics. relief systems: their types and location. ”Safety and Accident prevention in Chemical Operations. Taylor & Francis Group References: 1. electronic structure calculations. semi-empirical and density functional theory calculations. its estimation. noise. New York. Reaction of the molecules. Dynamics with continuous potentials. vibrations. government role. TBE044: Molecular Modeling and Drug Design L T P 3 1 0 UNIT I Introduction to Molecular Modelling. D. release of hazardous materials. Systematic search. pressure. Molecular Dynamics using simple models. assemblies of molecules. H. ab initio. UNIT III Toxic substances and degree of toxicity. Drawbacks of mechanical models as compared to graphical models. torsional term. vapor. cloud and mist explosion. 2nd Edition”.

Characterization and maintenance of cell lines. UNIT V 3D Pharmacophores. Selection of medium and serum. Scale and complexity. Preparation and sterilization of cell culture media. serum and other reagents. Application of cell culture technology in production of human and animal viral vaccines and pharmaceutical proteins. References: 1. Fluidized bed reactors for suspension culture. 3D data base searching and virtual screening. combinatorial libraries – generation and utility. Free energies and solvation. molecular similarity and similarity searching. construction of frame work . Antibiotics growth supplements. VCH. Cell separation. Continuous cell lines. Physiochemical properties. Perfused suspension cultures. UNIT IV Cell culture reactors. Commercial scale production of animal cells. Grant & W. Heltje & Gerd Folkens. CO2 and bicarbonates. Principles and applications of modelling by Leach 2. Mixing and aeration. side chain placement and refinement. Behavior of cells in culture conditions: division. Other cell culture reagents. UNIT III Cell cloning and selection. Transfection and transformation of cells. Cryopreservation. Temperature.selecting variable regions. Secondary culture. biological activities. validation of protein models –Ramchandran plot. Conditioned media. Types of cell culture media. Ingredients of media.Modelling by Homology-the alignment. Trypsinization. Chicken liver and kidney culture. Graham Richards. UNIT V Introduction to QSAR. Oxford University Press (PE-V) TBE051: Animal Biotechnology L T P 3 1 0 UNIT I Basic cell culture techniques. Chemical Applications of Molecular Modelling by Jonathan Goodman. Multisurface propagators. Scale-up in suspension. molecular modelling in drug discovery. Oxygen. metabolism of estimation of cell number. Rotating chambers.. Serum free media. lead module. 3. Computational Chemistry by Guy H. Sources of data. Molecular Modelling by Hans Pieter. Scale-up in monolayers. Buffering. Testing of toxicity of environmental pollutants in cell culture. Surface tension and foaming. Trypsin solution. electrostatic and non-electrostatic contribution to free energies. physicochemical parameter and molecular descriptors. Osmolarity. threading and ab initio modeling. Text Books: 1. . Foetal bovine serum. De novo Ligand design. Types of primary culture. growth pattern. stem cells. molecular docking. Roller culture. Suspension culture. Development of cell lines. Multiarray disks. linear and nonlinear modeled equations. spirals and tubes. Organ culture etc. Common cell culture contaminants. Balance salt solutions. Application of animal cell culture for in vitro testing of drugs. Chicken embryo fibroblast culture. Microcarriers. UNIT II Different tissue culture techniques. stem cells and their application.

Transgenesis and Xenotransplants. Text books: 1. Training manual for embryo transfer in cattle (FAO Animal Production and Health Paper-77). Detection technology. I. genotyping/SNP detection. Linkage and pedigree analysis. FISH to identify chromosome landmarks. Integration of foreign genes and their validation. UNIT II Genome sequencing Human genome project-landmarks on chromosomes generated by various mapping methods. Gordon. Physical maps. Gene targeting. 2. Phylogenetics. W. Pairwise and multiple alignments. DNA sequence. RFLP. Hafez and E. 1st Edition. BAC libraries and shotgun libraries preparation. 1991 References: 1. Comparative transcriptomics. Genetic variation-polymorphism.E Hafez. Improving transgene integration efficiency.context.D. Hoard and sons FAO. Growth monitoring UNIT V Transgenic animal production.deleterious mutation. CRC Press. Laboratory production of cattle embryos. Seidel. Applications: Global gene expression analysis.M. Hepatitis C virus or a bacterial pathogen. DNA fingerprinting. Physical map-cytogenetic map. RAPD. Matrix perfusion. mitochondrial and chloroplast genomes. Cell lineages and developmental control genes in drosophila and mice.g. Reproduction in farm animals.16S rRNA typing/sequencing. 1997.finding genes and regulatory regions. Comparative genomics of relevant organisms such as pathogens and nonpathogens. and S. Stem cell markers. Wiley Blackwell. Model organisms and other genome projects. Louis-Marie Houdebine. G. Construction of genetic maps. B. Methods and strategies. Jr. Taxonomic classification of organisms using molecular markers. Hollow fiber perfusion. Tools for genome analysis–PCR. restriction map. Evolution of a pathogen e. Stem cell differentiation. 2003. Differential gene expression. Similarity searches. Differentiation of cancerous cells and role of protooncogenes. Differentiation of germ layers.Perfused monolayer cultures.S.E. DNA sequencing and sequence assembly. Using stem cells for SCNT. Alignment statistics. Computational analysis of sequences. CAB International. Transgenic Animals: Generation and Use 5th Edition. 2000 2. Blood cell formation. networks. TBE052: Genomics & Proteomics L T P 3 1 0 UNIT I Introduction to Genomics Structure and organization of prokaryotic and eukaryotic genomes nuclear. Seidel. UNIT III DNA Microarray technology Basic principles and design: cDNA and oligonucleotide arrays. Fibroblasts and their differentiation. Computational analysis of microarray data. Prediction of gene function using homology. contig map. Automated DNA sequencing. 7th Edition. 2nd edition. UNIT IV Proteomics . structures. Microencapsulation. Gene annotation. Methods of stem cell production in farm animals. Cellular polarity. Membrane perfusion. Methods of transgene delivery.

Establishment and maintenance of callus and suspension cultures. Principles of Gene Manipulation and Genomics. Spot visualization and picking. Arthur Lesk. Genomes. pull-down assays (using GST-tagged protein). 2007. nif genes. spray sources). Tryptic digestion of protein and peptide fingerprinting. allele-specific PCR). TBE053: Plant Biotechnology L T P 3 1 0 Unit-I Historical background. Polymorphism detection without sequence information: SSCP.diagnostics. applications. Prions. analyzer (ToF. in vitro clonal multiplication – Meristem culture and virus elimination Unit-III Arabidopsis as a model plant for genetic engineering. ASM Press. 2nd Edition. tertiary and quarternary structure. Somatic embryogenesis Unit-II Haploid production -Androgenesis. Polymerization based assays (allele specific nucleotide incorporation. Glick BR & Pasternak JJ.. Introduction to Genomics. totipotency. far western analysis.Plant micropropagation. Nutritional requirement of plant cells. Brown TA. Text Books: 1. Metagenomics. Phage display. Laboratory organization. secondary. 4 Primrose S & Twyman R. Phenylketonuria (monogenic) and diabetes (multigenic) genetic disorders. Blackwell. Identification of drug targets. Protein interaction maps. Mass spectrometry : ion source (MALDI. quadrupole. Proteomics and drug discovery. Brief idea about molecular farming Unit-IV . Outline of a typical proteomics experiment. 3rd Edition. Proteomics and Bioinformatics. Gynogenesis. Protein-protein interactions: Solid phase ELISA. 5. clinical proteomics and disease biomarkers. Oxford University Press. High throughput screening for drug discovery.Overview of protein structure-primary. Protein arrays-definition. Hemoglobin and the anemias. Toxicogenomics. Concept of tissue and organ culturing. DNA polymorphism including those involved in disease. 2006. 2008 2. Discovering Genomics. Protoplast isolation and culture. Yeast two hybrid system. Identification and analysis of proteins by 2D analysis. Relationship between protein structure and function. Cellular differentiation and regulation of morphogenesis. ‘susceptibility’ gene. Molecular Biotechnology. Campbell AM & Heyer LJ. 2006. References: 1. expression profiling. Somatic hybrid- cybrids. 7th Edition. Benjamin Cummings. Ligation based assays (allele specific oligonucleotide ligation). UNIT V Human disease genes. Terminator seed technology. quadrupole ion trap) and detector. Embryo culture and rescue in agricultural and horticultural corps. Biological nitrogen fixation. Edible vaccines. 1998. 3rd Edition. by surface plasmon resonance technique. ‘disease’ gene vs. Media composition –solid and liquid. proteins in disease. SNP detection: hybridization based assays (allele specific probes). Garland Science. Anther and microspore culture. Pharmacogenomics and pharamacogenetics and drug development.

Flat plate. Biomass. hairy root induction and design of reactors for mass cultivation of hairy roots Unit-V Developing insect-resistance. Solar Photovoltaic System : Photovoltaic effect. Plant Cell Culture: A practical approach. Water power. Solar collectors. Energy plantation. disease-resistance. L. UNIT II Solar Energy : Solar thermal power and it’s conversion. Community biogas plants.P. Energy recovery from urban waste. SRC Series of Current Topics in Plant molecular Biology. 2. Applications of PV system. P. Thermal analysis of solar collectors. Bio gas applications. Thermodynamic limits to concentration. Aerobic and anaerobic bio-conversion process. Energy planning.Chawla References: 1. Raw materials. 1994. Walton. S. Solar thermal. Biomass gasification. Problems involved in bio gas production. bio gas plant technology & status. Power generation from liquid waste. Decentralized and dispersed generation. Tracking CPC and solar swing. solar cooking. Plant Cell Culture. Introduction to various sources of energy. Different systems. Producer gas. Efficiency of solar cells. Anderson. 4. TBE054: Non Conventional Energy Resources L T P 3 1 0 UNIT I Energy Resources and Their Utilization : Indian and global energy sources. Properties of bio gas. 5. Solar thermal energy storage. Bhowjwani. Solar photovoltaic system. Performance analysis of flat plate collector. Fuel properties. Hydrogen energy systems.Plant cell/tissue cultivation in bioreactors: Shear sensitivity of plant cells and mass cultivation in bioreactors. Semiconductor materials for solar cells. Water heating. yield increase in plants: case study of golden rice. Greenhouses. . Tidal and wave energy. Introduction to Plant Biotechnology Second Edition H. Dixon. Gresshoff.S. herbicide resistance in plants and stress tolerance in plants. Solar distillation. modification of colour. Types of concentrating collectors. Principles and Practices in Plant Science. UNIT III Biogas :Bio gas production. 3. Biomass resource development in India. Biomass conversion techniques. PV hybrid system. Solar concentrating collectors.A. Applications. Photovoltaic. Plant Tissue Culture: Application and Limitations. energy-GDP elasticity). Space heating & cooling. Energy exploited. Transportation of bio gas. Biomass cogeneration. Solar pond. fruit softening. Energy parameters (energy intensity. 1990. Advances in Biochemical Engineering and Biotechnology. Public concerns about transgenic crops Text Books: 1. Standards of solar photovoltaic system.D. Cylindrical collectors. Prentice Hall 1988. Geothermal energy. Solar power plants. solar pumping.M. Ocean thermal. Fuel cells. Wind energy.S. Plant Biotechnology and Development.

power generation.P. Reusable cells. Ashok V. Reference: 1. and health benefits of fermented milk foods products. Properties of thermoelectric materials. Historical Developments. “Renewable energy resources and emerging technologies”. Future potential of fuel cells. mushroom and algal protein). Role and significance of microorganisms in foods. Single cell protein (yeast. Geothermal Energy: Structure of earth’s interior. Site selection for geothermal power plants. Wind machine fundamentals. evaporation. Cost of electricity production from different energy sources. Ocean Energy: Principle of ocean thermal energy conversion. dehydration. UNIT V Thermoelectric Systems: Kelvin relations. Steam ejection. Intrinsic and Extrinsic parameters of Foods that affect microbial growth. Efficiency and EMF of fuel cells. Problems associated with ocean thermal energy conversion systems. Economic issues. Geothermal resources. Energy options for Indian economy. unit operations. Hot springs. Sources of hydrogen. Kothari D. MelissTata Mc Graw Hill. Bansal Keemann. Horizontal and Vertical axis wind mills. Selection of a wind mill. " Renewable energy sources and conversion technology". Availability of wind energy in India. Basic principles. Problems associated with geothermal conversion. and equipment involved in the commercially important food processing methods: blanching. Ltd. Comparison between acidic and alkaline hydrogen-oxygen fuel cells. Open Elective TBE 071: Food Biotechnology L T P 3 1 0 UNIT I History of Microorganisms in food. pasteurization and sterilization etc. Khanna Publishers. Fermentative production of food: Cheese. Geothermal sites. Fusion Plasma generators. . Other types of fuel cells. Rai G. wind velocity. Medical foods. yogurt. Pickling and bread making. 2. canning. Ideal fuel cells. Recent development.D. Production of hydrogen. Hydrogen Energy: Properties of hydrogen in respect of it’s use as source of renewable energy. Probiotics and prebiotics. Types of wind machines and their characteristics. Principal of working. Development of hydrogen cartridge. Advantages of fuel cell power plants. "Non-Conventional energy Sources". Storage and transportation..Wind Energy: Properties of wind. Problems with hydrogen as fuel. Economics of hydrogen fuel and its use. New Age International Publishers Ltd. Prentice Hall of India Pvt. "Nonconventional Energy". Text Books: 1. UNIT II Food Production technology: Starter cultures. 2. Advanced concepts. UNIT IV Electrochemical Effects and Fuel Cells : Principle of operation of an acidic fuel cell. Desai.

Lindsay. New York. Text Books: 1. Bibek Ray. Robert J. using food additives and Irradiation. Food Preservation with Low Temperature. rights. Mechanism and advantages of food preservation by Lactic acid Bacteria. and Weshoff. Appropriate case studies. remedies against infringement – civil and criminal. Drying. Indian patent act 1970 (amendment 2000).C. High Temperatures. Essentials of human nutrition. New Delhi. 2009. 2. Willis Elsevier.UNIT III Technology for improved process Enzyme in bakery and cereal products.M. 3.. major ingredients present in different product. CRC PRESS References: 1. UNIT V . Challenges for the flavour and Food Industry.. Applied Science Biotechnology. T. 2007. UNIT IV Food quality and control Analysis of food. invention step and prior art and state of art. Glucose oxidase in food Processing. Gordon.. procedure UNIT III Rights/protection. B.. McGraw Hill Book Co. Food Biotechnology. 1989. UNIT IV Detailed information on patenting biological products.. Use of fermentation for Food preservation. Roger. 1988. Utilization of food waste for production of valuables. Protease in cheese making and beverage production. 4. flavour. 2005. Fundamental food microbiology. UNIT V Food Preservation Technology Storage stability. Frazier. Other Proven and Suspected Food-borne Pathogens. Jay. 3. A. Rheology of Food Production. Requirement of a patentable novelty. Enzymes in Food Technology. 3rd edition . design and copy right. 4th Edn. and John. duties and their correlation. Enumeration and Detection of Food-borne Organisms.oxford university press. Budapest treaty. 1987. Mann & Trusswell . vitamins. 2. Biosafety & IPR L T P 3 1 0 L T P 3 1 0 UNIT I Jurisprudential definition and concept of property. Modern Food Microbiology.like patent. Whitehurst & Maarten van Oort. Microbial food additives: colour. W. Indicator and Food-borne Pathogens. UNIT II Distinction among various forms of IPR. Biodiversity. History and evolution of IPR. infringement or violation. D. CBS Publications. Wiley TBE 072: Bioethics. Enzymes in fat/oil industries. 1988. major changes in Indian patent system as post TRIPS effects (i) obtaining patent (ii) geographical indiation. Bioassay and related Methods.. Food Microbiology. J.S.

stem. Ane/Rout Publishers. 2. K. Risk assessment of Biotechnology Product. “Genetics” John Wiley & Sons. Das and Datta. in situ polymerization UNIT II Biologically Derived Biomaterials and Fermentative Production . fruit and seed. UNIT -II Cell cycle. Inc. Phillipe Cullet.freeman and Company. polymer isomerism. Classification of the living organisms (five kingdom classification. Ajay Poul. Cell organelles and their function. Risk assessment for Planned introduction. epitopes and haptens. genetic code. Morphology. crossing over. leaf. UNIT –III Mendelian inheritance. Concept of genes and gene organization. Gardener. “Genetics-Classical to Modern” Rastogi Publication(2007). mutations.H. respiration and photosynthesis processes. New Age International Publishers TBE 074: Biomaterial Science and Technology L T P 3 1 0 UNIT I Introduction and Selection of Biomaterials Definition of polymers and biomaterials. Ganguly. Risk Regulation. fiber folding. New York 5. Various cells and organs involved in immune response. Structure and classes of antibody Text Books: 1. mitotic and meiotic cell division. Sex determination. flower. Selection criteria. Thomas. anatomy and functions of different parts of flowering plants: Root. UNIT – V An introduction to Immunology.Biosafety. goldsby. Systematic and binomial system of nomenclature. innate and acquired immunity. Risk Assessment. Osborne. “Text Book of Cell and Molecular Biology” Books and Allied(P) (2007). Simmons & Snustad.IV Tissues in animals and plants. Prokaryotic and eukaryotic cell. major groups and principles of classification within each kingdom). TBE 073: Fundamentals of Biology L T P 3 1 0 UNIT -I Characteristics of living systems. 2. Ldexix Nexis Butterworths.(1991). functionality. “College Botany” New Central Book Agency(2007). Nature of antigens. Biosafety level. linkage. Biotechnology & Safety Assessment. Reference Books: 1. Plant and animal cell. 3. introduction and Bioethical issues in Biotechnology Text Books: 1. P. Biosafety Guidelines in India. 4. W. Immunology: Introductory text book by Nandini Shetty. Intellectual Property Protection & Sustainable Development. Gupta. inflorescence. Immunology 6th edition by Kindt. UNIT . membrane lamination.

B. 2. vertical. double effect evaporators. 6. Study of coupling of manipulated and controlled variables using relative gain analysis (RTA). separation of Biomaterials by cell digestion and extraction Text Books: 1. Biopolyester. Recommended to be done using a Simulation Language/Programming Environment 1. J. synthesis in organism and extraction. Dynamic simulation & controllability analysis of Binary distillation column. 4. Steinbuechel – Biopolymers. 2.characterization. Design of a Flow network containing Pumps. D. New York. 1991. polylactides. Stockton press. Simulation Language /Programming Environment (MATLAB). Plenum Pulo. polymer coated blood. Recommended Software 1. Dynamic simulation of Simple process systems with controllers 2. Byrom. Genetic and molecular Biology aspects of synthesis UNIT IV Trends in Biocomposite Biodiode . microbial cellulose. polyglutamic acid UNIT III Materials for Tissue Engineering and Improved Functions of Biopolymers Case studies with regenerated polymers. Plant or Aspen Plus/Aspen Dynamic) 2. 5. Steady state/Dynamic simulator (such as Hysys. References: 2.etc.Polyhydroxialkanoates. Separation Statistical optimization of probable variables for production of biomaterials. polymer precursor synthesis and characterization UNIT V Optimization of Production Kinetics. Tubular) with or without heat transfer. Process design & Rating of TEMA Type Shell &Tube Heat exchangers. use of reactors. bioadhesive. Biomaterials science and engineering. Process design of simple reactors (CSTR. A. Biomaterials –novel materials from biological sources. Process design & Rating of stand alone Multi-component Distillation columns. kinetic analysis for production. Finally he/she .Here the students are supposed to do the detail work as scheduled in the last semester. Steady state flow sheeting of acyclic processes. Steady state flow sheeting of Processes with recycles /Purge/Bypass etc. fittings and Piping (horizontal.Park. Laboratory Courses PBE801: Bioprocess Plant Design Lab L T P 0 0 2 Recommended to be done using a commercial simulator 1. 3. 1984. inclined) 2. PBE802: Project-II L T P 0 0 12 This project course is in continuation of project-I course allotted in the beginning of the VII the semester . Recommended to be done using a commercial simulator 1. Study of dynamic behavior of simple systems such as tank in series. microbial polysaccharides.

.will be required to submit a detailed project report on which viva-voce examination will be conducted by a committee having one External Examiner.