Many overweight people and those with type II diabetes take statins to lower their cholesterol levels.

Although statins are not a way to lose weight, they are helpful in reducing the high cholesterol levels that often accompany obesity. My primary are of interest is weight loss and providing people with a way to lose weight. However, since so many of the dieters that I encounter also take statins, I felt compelled to write this article so that people can mitigate the side effects of statins. Cholesterol-lowering drugs are one of the most over-prescribed drugs on the market today. Statin drugs such as Lipitor®, Pravachol® and Crestor® can significantly deplete your levels of the essential nutrient known as coenzyme Q10 (CoQ10). Research shows that these prescription drugs can lower your CoQ10 levels by up to 40 percent. The depletion of the essential nutrient coenzyme Q10 (CoQ10) by the extraordinarily popular cholesterol lowering drugs, HMG-CoA reductase inhibitors (statins) has grown from a level of concern to one of alarm. As a side note, HMG-CoA reductase is a liver enzyme that regulated cholesterol production, all statins work by inhibiting this enzyme. With increasing statin potencies and higher dosages prescribed by doctors, and with a decreased target LDL cholesterol, the prevalence and severity of CoQ10 deficiency is increasing rapidly. An estimated 36 million Americans are now candidates for statin drug therapy. CoQ10 serves as the coenzyme for mitochondrial enzyme complexes and is essential for mitochondrial ATP(adenosine tri-phosphate) production. As a side note ATP is the substance, synthesized in your body that is the source of energy for all cellular functions. CoQ10 is also a clinically relevant fatsoluble antioxidant. It is found normally in the diet, predominantly in organ meats and is biosynthesized in all cells with peak capabilities in late teens and early twenties with a gradual age-related decline after the age of 30 years. Statin-induced CoQ10 depletion is well documented in animal and human studies with detrimental cardiac consequences in both animal models and human trials. Furthermore, this drug-induced nutrient deficiency (caused by taking statins) is dose-related and more notable in settings of pre-existing CoQ10 deficiency such as in the elderly and in heart failure. Finally, statininduced CoQ10 deficiency is completely preventable with supplemental CoQ10 with no adverse impact on the cholesterol lowering or antiinflammatory properties of the statin drugs.

The heart is usually the first organ to to be affected by statin associated CoQ10 depletion because of its extremely high energy demands. Physicians are seeing this as cardiomyopathy and congestive heart failure. Chronic fatigue is also being reported and we must remember that every cell in the body is dependent upon an adequate energy reserve. We are currently in the midst of a congestive heart failure epidemic in the United States, the cause or causes of which are unclear. It is important to be certain that we are not inadvertently doing harm to our body’s by creating a wide-spread deficiency of a nutrient critically important for normal heart function.

CoQ10, discovered in 1957, provides 95 percent of your body’s energy. And your heart requires up to 10 times more CoQ10 than any other organ in your body. If CoQ10 levels drop, your skin cells get older faster, your lung cells choke, your liver cells fill with toxins, your brain cells start to shut down, and your heart cells may stop beating. For patients taking cholesterol-lowering drugs, damage like this has been seen in as little as 12 weeks, according to the Journal of the American Medical Association More than 1,000 published studies report that this Nobel Prize-winning nutrient can help you:
    

Strengthen and protect your heart Avoid brain problems Boost healthy blood circulation Maintain free and clear arteries Restore healthy heartbeats

The best form of CoQ10 to take is unbiquinol. You can purchase it at most health food stores or on line at a variety of popular sites.. By supplementing with CoQ10 patients have experienced remarkable clinical results. Within 30 days of taking the CoQ10 supplement, 75 percent of patients reported fewer heart rhythm disturbances, 66 percent of patients reported diminished chest pain and 50 percent fewer patients suffered from future cardiac events. Plus, after only eight weeks 87 percent of patients had improved heart function.