Explore Ebooks
Categories
Explore Audiobooks
Categories
Explore Magazines
Categories
Explore Documents
Categories
• Further developments
• More stable systems
• Supercritical is a thermodynamical
state, which lies above the
supercritical point.
• Environmentally neutral:
• CO2 is a waste product of
industrial processes
SFC
LC
phase phase
• Separation by solvent
• Separation by • Separation by solvent gradient
temperature gradient and density gradient
GC LC
SFC
Efficiency Efficiency
Selectivity Selectivity
Efficiency
• Modifiers and additives are used to modify elution strength of the mobile
phase.
• Modifiers: methanol, ethanol or isopropanol, etc.
• Additives: Salts, acids or water, etc.
CO2 Modifier
Binary pump
Back
Autosampler
Pressure
Regulator
Advanced
Column BPR detectors like
oven mass
spectrometry
UV-Vis detector
• Chiral:
• Structural isomers:
• The elution strength of the mobile phase can be altered by using modifiers
and additives