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Surfactant

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Contents

1 Overview

2 Classification Of Surfactant

3 Applications

4 Contact us
Overview
Surface tension

Two liquids
A gas and a liquid,
A liquid and a solid
2 Overview

Hydrophobic groups Hydrophilic groups

Amphiphilic

A surfactant contains both a component and a


water-soluble component

Activity

Surfactants will diffuse in water and adsorb at


interfaces between air and water or at the
interface between oil and water, in the case
where water is mixed with oil. The water-
insoluble hydrophobic group may extend out of
the bulk water phase, into the air or into the oil
phase, while the water-soluble head group
remains in the water phase.。
2 Overview

Hydrophobic tails

The hydrophobic tails of the surfactant ions


remain inside the oil because they interact more
strongly with oil than with water.

Hydrophilic Head

The hydrophilic heads of the surfactant


molecules coating the micelle interact more
strongly with water, so they form a hydrophilic
outer layer that forms a barrier between
micelles.
1 Nonionic Surfactant

Classification 2 Anionic Surfactant


Of
3 Cationic Surfactant
Surfactant
4 Amphoteric Surfactant
1 Nonionic Surfactant

Water-solubility
The water-solubility of the oxygen
groups is the result of hydrogen
bonding.

Hydrogen bonding
Hydrogen bonding decreases with
increasing temperature, and the
water solubility of nonionic
surfactants therefore decreases
with increasing temperature.
2 Anionic Surfactant

Sulfate Sulfonate Phosphate Carboxylate

Ammonium Sodium Sodium Sodium


lauryl lauryl laureth myreth
sulfate sulfate sulfate sulfate
3 Cationic Surfactant

01 Amine salt type 02 Quaternary ammonium 03 Heterocyclic type


salt type
4 Amphoteric Surfactant

Cationic part Anionic part


Primary, secondary, or tertiary Be more variable
amines or quaternary ammonium
cations

Ø Phospholipids phosphatidylserine

Ø Phosphatidylethanolamine
Ø Sphingomyelins
1 Solubilization

2 Wetting agents

Applications 3 Foaming and defoaming

4 Sterilization
1 Solubilization

Structural Electrolyte
characteristics

Temperature Inorganic
additives
Organic
additives
2 Wetting agents

The purpose of adding surfactants is to increase the


adhesion and deposition of the drug, and to increase the
activity of active ingredient in the presence of moisture.
3 Foaming and defoaming

Oil-soluble Indispensable
celluloses emulsifiers

Steroid Suspending
hormones agents

Insoluble Foaming
drugs agents
4 Sterilization

Preoperative skin Mucosal disinfection Device disinfection Environmental


disinfection disinfection
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