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Axia College Material

Appendix C

Immune Response and Hypersensitivity

Puncture Wound Multimedia Activity

After completing the Puncture Wound Multimedia Activity, complete the table below. List the four
events of the inflammatory response covered in the activity in the order of occurrence. Rewrite
the events in your own words, using vocabulary terms from Ch. 2 of the text.

Vascular Events in an Inflammatory Response

Events Simplified description of event Professional description of event
Germs from the nail are introduced below A foreign object has punctured the skin,
the skin. bacteria gets in and multiplies. Hyperemia
1st causes neutrophils and polymorps to line
along the capillary walls and protect the
body from microorganisms
Surrounding cells leak fluid that affect the The tissue that is damaged releases
blood vessels. histamines into the body
The fluid affecting the surrounding blood Histamine is causes the blood vessels to
vessels causes the release of other cells expand and allow plasma and neutrophils
into the tissue. to move out of the blood vessels and into
the damagedtissue.
As the wounded part of the body reacts Polymorphs move to the bacteria in the
th to the germs, certain cells destroy these tissue by the chemotaxis and it ingests and
germs. destroys bacteria and toxins in the
damaged tissue.

Give a brief description and example in your own words for each of the four types of
hypersensitivity presented in Ch. 2.

Hypersensitivity Matrix
Type of Hypersensitivity Description Example
Type I: Allergic/Anaphylactic This hypersensitivity is triggered A person who is
by allergen binding to IgE on mast allergic to bee venom
cells, which produce local severe could suffer from
inflammation or systemic severe anaphylactic shock
Type II: Cytotoxic/Cytolytic IgM or IgG interacting with foreign An incompatable
cells to cause their destruction. blood transfusion.
Type III: Immune Complex Antigens combine with Farmers Lung caused
antibodies,forming immune by mold spore
complexes. inhalation.
Type IV: Cell-mediated/Delayed Expose to an antigen results in Contact with poison ivy
activation of a T-cell-mediated and organ rejections.
immune response

HCA 240