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The Membrane Selector Guide

Fit-for-purpose filtration starts here. Hydrophilic


Hydrophobic

Prefiltration/
Ultrafiltration Microfiltration
Clarification
Particle size: 10 µm+
Particle size: 1 kDa to 500 kDa Particle size: 0.025 µm to 10 µm Examples: Large particles in environmental
Examples: Proteins, virus, nucleic acids Examples: Bacteria including B. diminuta, microorganisms, samples and industrial fluids, total suspended
and nanoparticles undissolved excipients, dust, asbestos, mycoplasma solids in wastewater, cell aggregates and
Filter type: Ultrafilters Filter type: Screen filters multicellular organisms, pollen
Filter type: Depth and net filters

Ultracel®-PL Membrane MF-Millipore™ Membrane Durapore® Membrane Glass Fiber Filters


OH NO2
H H
CH2 OH C O O
O

+
H CH3 CH2 CH2
C Si

+
C
O O H H H H F F
n n
OH C NO1 C CH2
H H H H H H Brand Name Durapore® Membrane Membrane Material Borosilicate Glass or Quartz Microfibers
OH
n n
H n H n Membrane Material Polyvinylidene Difluoride (PVDF) Pore Sizes (µm) 0.2 – 8.0
Brand Name Ultracel®-PL Membrane NO2 C Pore Sizes (µm) 0.1 - 5 Thickness (µm) 230 - 1200
Membrane Material Regenerated Cellulose CH2 Thickness (µm) 80-140 Water Flow Rate (mL/min/cm2) 1.2 - 6.0
Pore Sizes (NMWL) 1 to 100 kDa Brand Name MF-Millipore™ Membrane Water Flow (mL/min/cm2) (hydrophilic) 4 - 208 Air Flow (L/min/cm2) @ 10 psi 10.6 - 139
Wettability Hydrophilic @27.5 in. Hg Wettability Hydrophilic
Membrane Material Mixed Cellulose Esters (MCE)
Chemical Compatibility Broad chemical compatibility, compatible with Air Flow (L/min/cm2) @ 10 psi (hydrophobic) 0.9 - 4.9 (typical values) Temperature Limitations 500 to 950 °C max
Pore Sizes (µm) 0.025 - 8
both aqueous and organic solvents Wettability Hydrophilic and hydrophobic options Chemical Compatibility Recommended for aqueous solvents
Thickness (µm) 105 -150
Sterilizability Autoclave, EtO and solvent incubation Refractive Index 1.42 Sterilizability Autoclave, EtO and gamma
Water Flow (mL/min/cm2) 20.1 - 625
Surface Option White @27.5 in. Hg Temperature Limitations 85 °C max Surface Option White
Key Properties Low protein binding, Polyolefin backing material Air Flow (L/min/cm2) @ 10 psi 0.12 - 68.9 (typical values) Protein Binding Capacity (IgG) < 10 µg/cm2 Key Properties Prefiltration down to 0.6 µm particles, high
provides support without impeding flow Porosity (%) 70 - 84 Chemical Compatibility Recommended for aqueous solvents temperature-compatible and non-shedding
Key Applications Concentration of protein solutions, separation Sterilizability Autoclave, EtO and gamma options, pure and binderless materials
Wettability Hydrophilic
of low from high molecular weight molecules, Surface Option White Key Applications Toxic Characteristic Leaching Procedure (TCLP),
Refractive Index 1.50 -1.52
protein binding studies, buffer exchange Key Properties Low protein-binding (hydrophilic), Total Suspended Solids (TSS), heavy metals
Temperature Limitations 55 °C max
Devices Amicon Ultra® devices, Stirred cell membrane solvent-resistant (hydrophobic) analysis, prefiltration, air monitoring
Protein Binding Capacity (IgG) 299 - 319 µg/cm2
discs, Microcon® devices, Centrifree® devices Key Applications Sterilizing filtration, clarifying filtration of Devices Millex® syringe filters, filter discs
Chemical Compatibility Recommended for aqueous solvents
protein-containing solutions, mycoplasma
Sterilizability Autoclave, EtO
reduction, gas filtration and venting
Surface Option Black, white, gridded
(hydrophobic), solvent filtration (hydrophobic)
Key Properties Versatile fast-flowing membrane, supports cell
Biomax® Membrane growth, high protein-binding
Devices Millex® syringe filters, Millipak® filters, Polypropylene Net Prefilters
MultiScreen® plates, Stericup® filters, Steritest™
Key Applications Sterilizing filtration, air monitoring, general devices, Sterivex™ filters, Ultrafree® filter units,
clarification, bacteriological analysis, drop filter discs
H CH3
dialysis, particle analysis, colony hybridization, C
S
nucleic acid and protein blotting, Elispot C
n
Devices Millex® syringe filters, Millicell® plates/inserts, H H
n
Cathivex® filters, MultiScreen® plates, Stericup®
Brand Name Biomax® Membrane filters, Steritest™ devices, Sterivex™ filters, Millipore Express® PLUS Membrane Membrane Material Polypropylene
Membrane Material Polyethersulfone (PES) Microfil® devices, filter discs Pore Sizes (µm) 25 up to 80
Pore Sizes (NMWL) 5 to 500 Thickness (µm) 320 to 450
Thickness (µm) 300 S Wettability Hydrophobic
Wettability Hydrophilic n Chemical Compatibility Compatible with aqueous solvents
Temperature Limitations 50 °C max Fluoropore™ Membrane Sterilizability Autoclave, EtO and gamma
Chemical Compatibility Compatible with aqueous solvents and alcohols Surface Option White
Compatible with pH 1-14 Brand Name Millipore Express® PLUS Membrane

+
F F H H Key Properties Large pore size options, good solvent resistance
Sterilizability Autoclave, EtO and solvent incubation C C
Membrane Material Polyethersulfone (PES) Key Applications General prefiltration and clarification , suitable
Surface Option White Pore Sizes (µm) 0.22, 0.45 for organic solvents
C C
Key Properties Low to moderate protein binding, high flow rate, Thickness (µm) 130 - 185 Devices Filter discs
F F H H
Polyolefin backing material n n Water Flow Rate (mL/min/cm2) 27 to greater than 44
Key Applications Concentration of protein solutions, separation @27.5 in. Hg
Brand Name Fluoropore™ Membrane
of low from high molecular weight molecules, Wettability Hydrophilic
Membrane Material Hydrophobic Polytetrafluoroethylene (PTFE)
buffer exchange Protein Binding Capacity (IgG) 22 µg/cm2
Devices Stirred cell filter discs
Pore Sizes (µm) 0.2 - 3
Chemical Compatibility Recommended for aqueous solvents
Polypropylene Prefilters
Thickness (µm) 50 -150 Membrane Material Polypropylene
Sterilizability Autoclave, EtO and gamma
Porosity (%) 85 Pore Sizes (µm) 0.6 - 30
Surface Option White, plain or gridded
Liquid Flow (mL/min/cm2) 24 - 286 (methanol) Thickness (µm) 95 - 145
Key Properties Fast flow, high throughput, low protein binding
@27.5 in. Hg Wettability Hydrophobic
Key Applications Sterilizing filtration of biological solutions
Air Flow specs (L/min/cm2) 5 - 20 Temperature Limitations 90 °C max
Devices Stericup® filters, Millex® syringe filters,
@ 10 psi
MultiScreen® plates, filter discs Chemical Compatibility Recommended for aqueous
Wettability Hydrophobic
Sterilizability Autoclave, EtO and gamma
Temperature Limitations 130 °C max
Surface Option White
Chemical Compatibility Compatible with both aqueous and organic
Isopore™ Membrane solvents
Key Properties High particle retention and dirt-holding
Sterilizability Autoclave, EtO Mitex™ Membrane Key Applications
capacity, low pressure drop
General prefiltration and clarification, suitable
CH3 Surface Option White for organic solvents
Key Properties Solvent-resistant, fast-flowing, low pressure F F
Devices Filter discs
C C C
drop, low extractables, low binding
CH3 n Key Applications Clarifying acids, bases and solvents, air C
monitoring, filtering and venting gases, UV F F
n
Brand Name Isopore™ Membrane spectroscopy, radiation monitoring
Membrane Material Polycarbonate Devices Millex® syringe filters, filter discs Brand Name Mitex™ Membrane Nylon Net
Pore Sizes (µm) 0.1 - 10 Membrane Material Hydrophobic Polytetrafluoroethylene (PTFE) Membrane Material Nylon
Thickness (µm) 21 - 27 Pore Sizes (µm) 5 - 10 Pore Sizes (µm) 10 -180
Porosity (%) 5 - 10 Thickness (µm) 125 - 200 Thickness (µm) 45 -135
Water Flow Rate (mL/min/cm2)
@ 10 psi
0.5 - 250 LCR Membrane Water Flow (mL/min/cm2) 47 to greater than 125 Porosity (%) 4 to 53
@27.5 in. Hg Wettability Hydrophilic
Air Flow (L/min/cm2) @10 psi 1.3 - 72 ( typical values) F F Air Flow (L/min/cm2) @ 10 psi 117 - 167 Chemical Compatibility Compatible with both aqueous and organic
Wettability Hydrophilic C Wettability Hydrophobic solvents
Refractive Index 1.6 Temperature Limitations 260 °C max Sterilizability Autoclave, EtO and gamma
C
Temperature Limitations 140 °C max F F Chemical Compatibility Compatible with both aqueous and organic Surface Option White
Chemical Compatibility Compatible with both aqueous and organic n solvents Key Properties Large pore size options, uniform pore structure
solvent Sterilizability Autoclave, EtO Key Applications Cell collection, large particulate filtration,
Brand Name LCR Membrane
Sterilizability Autoclave, EtO and gamma Surface Option White, plain or gridded particle analysis, flow cytometry sample prep,
Membrane Material Hydrophilic Polytetrafluoroethylene (PTFE)
Surface Option White, brown Key Properties Pure PTFE (unbacked), easy handling, solvent- toxicology and drug screening on C. elegans
Pore Sizes (µm) 0.45 only
Key Properties Narrow pore size distribution, collects particles resistant, fast-flowing, low extractables and zebrafish
Thickness (µm) 140
on surface for analysis Key Applications Clarifying acids, bases, solvents and cryogenic Devices Steriflip® filters, filter discs
Porosity (%) 80
Key Applications Particle analysis, air monitoring, microscopy, fluids, hydraulic fluid analysis
Water Flow Rate (mL/min/cm2) 28.4
cell migration and chemotaxis assays, Devices Millex® syringe filters, filter discs
@27.5 in. Hg
epifluorescence, size fractionation of cells and
Air Flow (L/min/cm2) @ 10 psi 1.1 (typical values)
particulates
Devices Millicell® plates/inserts, MultiScreen® plates,
Wettability Hydrophilic Reinforced Prefilter Membrane
Temperature Limitations 130 °C max Membrane Material Mixed Cellulose Esters around a polyester web
filter discs
Chemical Compatibility Compatible with both aqueous and organic Immobilon® Membrane Pore Sizes (µm) 0.2 - 1.2
solvents Thickness (µm) 150 to 270
Sterilizability Autoclave, EtO H H
Water Flow Rate (mL/min/cm2) 12 - 260
C
Surface Option White
Omnipore™ Membrane Key Properties Minimal extractable levels, broad chemical C
Wettability
Temperature Limitations
Hydrophilic
70 °C max
compatibility F F
n Chemical Compatibility Recommended for aqueous solvents
F F
Key Applications HPLC mobile phase filtration, clarifying acids, Sterilizability Autoclave, EtO
C
bases and dilute protein solutions Brand Name Immobilon® Membrane Surface Option White
C Devices Millex® syringe filters, Millex Samplicity® filters, Membrane Material Polyvinylidene Difluoride (PVDF)
F F Key Properties Non-shedding, high dirt-loading capacity, low
n filter discs Pore Sizes (µm) 0.22 - 0.45 pressure drop
Wettability Hydrophobic Key Applications Prefiltration ahead of sterilizing grade filters
Brand Name Omnipore™ Membrane Protein Binding Capacity (IgG) Avg 333.4
Membrane Material Hydrophilic Polytetrafluoroethylene (PTFE) Devices Filter discs
Chemical Compatibility Compatible with both aqueous and organic
Pore Sizes (µm) 0.1 - 10
Thickness (µm) 30 - 85
Nylon Membrane solvents
Sterilizability Autoclave, EtO and gamma
Water Flow Rate (mL/min/cm2) 2 - 1250 Membrane Material Nylon
Surface Option White
@8.97 in. Hg Pore Sizes (µm) 0.2 - 1.2
Key Properties High protein-binding, durable
Wettability Hydrophilic Thickness (µm) 150 - 190
Key Applications Protein blotting (Western), Elispot
Chemical Compatibility Compatible with both aqueous and organic Water Flow Rate 8.0 - 21.2 (typical value)
Devices Membrane roll stock and sheet,
solvents (mL/min/cm2)@ 27.5 in. Hg
MultiScreen® plates
Sterilizability Autoclave, EtO Wettability Hydrophilic
Surface Option White Chemical Compatibility Compatible with both aqueous and organic
Key Properties Compatible with both aqueous and organic solvents
solvents, broad chemical compatibility Sterilizability Autoclave, EtO and gamma
Key Applications Clarifying acids, bases and aqueous solutions Surface Option White
Devices Membrane Key Properties General purpose, good solvent resistance
Key Applications Particle removal and clarification of solvents,
particle analysis
Devices Millex® syringe filters, filter discs

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