Professional Documents
Culture Documents
(For the candidates to be admitted from the academic year 2005-2006 onwards)
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Language Course – IV (LC) 6 4 3 25 75 100
English Language Course – IV (ELC) 6 4 3 25 75 100
Core Course V- Practical II: Physiology & 2 4 3 25 75 100
Biochemistry
IV Core Course – VI (CC): Plant and Animal 6 4 3 25 75 100
Biotechnology
Core Course VII (CC): Bio statistics 3 - ** - - -
Second Allied Course – II (AC) – Organic 2 3 3 25 75 100
chemistry
Second Allied Course I & II- Practical – 5 3 3 25 75 100
Inorganic and Organic chemistry
The Department of Bioinformatics will offer the following Elective Courses (ECs)
Elective Course I. Biotechniques For B.Sc. Bioinformatics
Elective Course II. Genetics and Evolution students
Elective Course III. Biophysical Sciences For other Department
Elective Course IV. Computer and its Application in Biology students
* Examination at the end of even semester
** Examination at the end of fifth semester
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SEMESTERS - I & II
Unit – I : Universal cell concepts : Cell as unit of life – Structure of prokaryotic and
eukaryotic cells – Differences and Similarities in plant and animal cells. Cell
transport across Plasma membrane – Mechanism of transport in vascular plants
and animals. Cell reproduction, Cell Cycle, Mitosis and Meiosis.
Unit – III : Plant physiology : Cell energetics and respiration - Energy capture-
Photosynthesis - Role of ATP in energy cycle - Utilization of glucose and
glycolysis- Mitochondrial respiration –Phosphorylation.
Reference Books
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CC – II Practical – I Basic Techniques in Cell Biology and Computer Applications
Suggested Readings
Unit - II Groups – Types – simple properties of groups – cyclic Groups and subgroups.
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Unit - III Measures of central tendency of a set of observations – Purpose of statistical
investigations – The arithmetic mean – The mean of grouped data – The median –
The mode – The measurement of Variability, range, mean deviation, Variance and
Standard deviation.
Unit - V Basic concepts of Probability – sample space and events – The use of
counting methods in Probability Addition law – Conditional Probability –
Simple problems involving the estimation of probabilities – Normal
distribution and Binomial distribution with their application and biology.
Text Books :
1. For Unit I :
“ Discrete Maths”, by B.S.Vatssa; Wishwa Prakashan (A Division of Wilcy
Eastern Limited) 1993.
2. For Unit II :
“Algebra, by Arugam Issac. New Gamma Publishing – House –
Palayamkkottai 1997
3. For Unit III, IV, V :
Relevant portion in Gupta S.P. Statistical Methods, Sultan Chand and sons
guarantee 1996
Reference Books :
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Unit : V Sequencing Problems – Processing ‘n’ jobs through two machines –
Travelling Salesman Problems as an application of Sequencing.
Text Books
Reference Books
Text Books
Reference Books
1. Transformation geometry
2. Modern Algebra by Sri S.Narayanan and Sri T.K.Manickavachagam
(S.Viswanathan Printers and Publishers Pvt.Ltd, 1993)
3. Theory of Computing by John – C Martin – MC Graw – Hill series -1993.
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SEMESTER – III
UNIT I
Scope of physiology – Body organization - Homeostatic mechanisms: Temperature and pH
regulations in animals – Physiology of digestion – Composition and Functions of Blood –
Respiratory pigments (Hb, Mb) – Transport of Gases.
UNIT II
Mechanism of Urine Formation – Mechanism of Muscle Contraction – Nerve Impulse
Transmission – Hormones– Mechanism of hormone action.
UNIT III
Scope of Biochemistry – physical and chemical processes of living systems – water and its uses
– dissolved gases and their properties – pH and buffers - Classification, Structure and Functions
of Bio molecules (Carbohydrate, Protein, Lipid & Nucleic acid) – Vitamins.
UNIT IV
UNIT - V
Text Books:
1. P.S. Verma, and V.K. Agarwal, Animal physiology, S.Chand & co., 1992.
2. R.S. Nagabushnam, Animal physiology, S. Chand & co., 1991.
3. Ambika Shanmugam, Fundamentals of Biochemistry for medical students, 2001.
4. J.L. Jain, Fundamentals of Biochemistry, S. Chand & Company LTD, 1999.
Reference Books
1. W.S. Hoar, General & Comparative Physiology, Prentice Hall of India, 1983.
2. C.L. Prosser, and F.A. Brown, Comparative Animal physiology, W.B. Suanders, 1985.
3. S.C. Rastogi, Biochemistry, Tata McGraw Hill publishing limited, 1996.
4. R.K.Murray, D.K.Granner, P.A.Mayes and V.W.Rodwell, Harper’s Biochemistry,
McGraw hill companies, 2000.
5. L. Stryer, Biochemistry, Freeman company, New York, 1995.
6. Lehninger,Biochemistry, Worth Publications inc., CBS Publication, New Delhi, 2000.
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CORE COURSE V- PRACTICAL II – PHYSIOLOGY, BIOCHEMISTRY AND
BIOTECHNOLOGY
PHYSIOLOGY:
BIOCHEMISTRY:
PLANT BIOTECHNOLOGY
ANIMAL BIOTECHNOLOGY
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SECOND ALLIED COURSE-I (AC) - PHYSICAL AND INORGANIC CHEMISTRY
UNIT – I
Physical Chemistry :
Introduction to physical chemistry: The nature of gaseous state: States of matter gas, liquid,
solid. Gas laws – Boyle’s law, Charles law, Gay – Lussac’s law, Avagadro’s hypothesis.
Dalton’s law of Partial pressures, Graham’s law – Combined gas law – ideal gas – kinetic theory
of gases – Deviations from the ideal gas law – Van der Wal’s equation – real gases.
UNIT – II
UNIT III
Inorganic Chemistry :
Atomic structure - Discovery of the sub-atomic particles: electrons, protons, neutrons;
Radioactivity – Bequerel and Curies, types of radiation. Determination of nucleus of atom,
isotopes, Bohr theory; quantum numbers-n,l,m and s; electronic configurations – orbital
designations – s, p, d, f orbitals. Shapes of s and p orbitals.
UNIT IV
3 2
Types of chemical bonds: lonic bonding - Covalent bonding – Orbital hyrbidisation (Sp , Sp ,
1
Sp only) - Multiple valency - electronegativitives and electron affinities - Geometry of simple
covalent compounds - oordinate covalent bonds.
UNIT V
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SECOND ALLIED COURSE-II (AC) - ORGANIC CHEMISTRY
UNIT I
UNIT II
UNIT III
UNIT IV
UNIT V
and biological importance of fat soluble and water soluble vitamins. Antibiotics: Chemotherapy
– Structures of chloromycetin, penicillin and streptomycin.
Reference books:
1. P.L.Soni & H.M.Chawla, Textbook of Organic Chemistry, Sultan Chand &Sons, 1994, Delhi.
2. K.S.Tewari, S.N.Mehrotra and N.K.Vishnoi, A Text Book of Organic Chemistry.
3. M.K.Jain, Organic Chemistry, Shoban Lal Nagin Chand and Co.,
4. Spice, J.E., Chemical bonding and structure, 1964.
5. Winter, M.J., Chemical bonding, 1996.
6. Ernest Eliel, Stereochemistry of carbon compounds, 1996.
7. Paula Yurkanis Bruice- Organic Chemistry, Prentice Hall
8. B.S. Bahl and Arun Bahl, Advanced Organic Chemistry, S. Chand and Co New Delhi.
9. Chatwall - Organic chemistry of Natural Products.
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SEMESTER IV
CORE COURSE – VI PLANT AND ANIMAL BIOTECHNOLOGY
UNIT I
Concept of gene cloning – Cloning vectors: Plasmids, Phages, Cosmids, Phasmids, YAC – DNA
manipulative enzymes: Restriction endonuclease and Ligase.
UNIT II
Principles and techniques of Nucleic acid hybridisation – Proteins and Nucleic acids –Southern,
Northern and Western blotting techniques – PCR – RFLP – RAPD.
UNIT III
Recombinant DNA Technology: Principles and methods of genetic engineering and gene
targeting – Applications in agriculture, health and industry.
UNIT IV
Plant Tissue Culture: Culture media – Primary culture – Cell line – Cell clones – Callus culture –
Somoclonal variation – Micro propagation – Somatic embryogenesis – Protoplast fusion –
Cybrids –Artificial seeds – Gene transfer methods in plants – Transgenic plants.
UNIT V
Animal Tissue Culture: Culture media – Embryonic stem cell culture – Tissue culture methods –
Production of Transgenic animals - Biochip Technology – Monoclonal antibody production.
Reference books
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CORE COURSE – VII BIOSTATISTICS
UNIT I
UNIT II
UNIT III
Basic concepts of Probability – Sample space and events – Addition and Multiplication theorem
– Theoretical distribution: Binomial, Normal and Poison.
UNIT IV
UNIT V
Tests of Significance: Small sample tests – Students‘t’ test for mean, difference of two means
and test for Correlation – Chi Square test for goodness of fit – F test for equality of variance.
Reference Books
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SECOND ALLIED COURSE - I AND II PRACTICAL
(INORGANIC AND ORGANIC CHEMISTRY)
1. VOLUMETRIC ANALYSIS
2. Permanganimetry
a) Estimation of ferrous sulphate
b) Estimation of oxalic acid
3. Iodometry
a) Estimation of copper
b) Estimation of potassium dichromate
c) Estimation of potassium permanganate
II ORGANIC ANALYSIS
The students may be trained to perform the specific reactions like tests for elements (nitrogen 39
only), aliphatic or aromatic, saturated or unsaturated and functional group present and record
their observations.
SEMESTER V
UNIT I
Diversity of Microorganisms – Salient features of Bacteria, Virus, Phages, Algae, Fungi and
Protozoan. Industrial applications of microorganisms in various fields.
UNIT II
Structure, Life history and Genomic Biology of E.coli, Helicobacter, Salmonella, Influenza,
Polio, Poxvirus, Diatoms, Chlorella, Spirulina, Aspergillus, Penicillum, Plasmodium,
Entamoeba.
UNIT III
UNIT V
Text Books
Reference Books
1. M.J. Pelczar, Jr., E.C.S. Chang and N.R. Krieg, Microbiology-concepts and applications,
McGraw Hill Company, 1993.
2. Tauro, P.K.K.Kapoor and K.S.Yadav, An Introduction to Microbiology,
Wiley Eastern ltd., 1993.
3. Basic and Practical Microbiology – Ronald M. Atlas, Mac.Milleen Company,
Newyork, 1986.
4. Shetty, N., Immunology, Wiley Eastern Ltd., 1997.
5. Janis Kubey, Immunology ,W.H.Freeman and Co.,New York, 2002.
6. I.M. Roitt, J. Brostoff and D.K. Male, Immunology, Gower medical publishing, London,
1993.
UNIT – I
UNIT – II
Proteins – Amino acids – Peptide bond –– Levels of protein structure - α-helix, β-sheet and β-
turns – Ramachandran Map - Super secondary structures – Domains - quaternary structure -
DNA and RNA structure - Watson and Crick model - A, B and Z forms of DNA - RNA
secondary structure.
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UNIT – III
UNIT - IV
Protein structure visualization tools – RasMol, Swiss PDB Viewer - Structure – Classification,
alignment and analysis – SCOP, CATH, FSSP.
UNIT - V
Reference Books
UNIT – I
UNIT – II
Data Input and Output – Control statements: if-else, switch, while, do-while, for, goto, break,
continue, exit and abort.
UNIT – III
Functions: Defining and Accessing Arguments – recursive functions – storage classes – Arrays:
Defining and processing Arrays – Multidimensional arrays – passing arrays to functions – Arrays
and strings – String functions – String Manipulations.
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UNIT – IV
UNIT – V
Data files – Opening, closing and processing files – files with structures and unions – register
variables – Bitwise Operations – Macros – Preprocessing.
Text Book:
1. Byron S.Gottfried – Schaum’s outline series, Programming with C, Tata McGraw Hill
Publications, 1998.
2. Yashavant P.Kanetkar, Let us C Solutions, BPB Publications, 2005.
3. Yashavant P.Kanetkar, Understanding Pointers in C, BPB Publications, 2001.
Reference Books :
SEMESTER VI
UNIT I
Purpose of database systems – View of data: Data abstraction –Instances and Schemas – Data
independence.
UNIT II
Data models:
ER Model: Entity and entity sets – Relations and relationship sets – ER diagrams – Reducing ER
diagrams to tables - Network data model: Basic concepts.
Hierarchical data model: Basic concepts.
UNIT III
UNIT IV
Databases in Molecular Biology - Nucleic acid sequence databases: NCBI- GenBank, EMBL,
DDBJ – Protein sequence databases: SWISSPROT, NBRF-PIR – Structure Databases – PDB,
NDB and Cambridge Crystallographic Database
Reference Books
UNIT I
UNIT II
Molecular mechanics - Newton’s laws of motion, Introduction to force fields, Components and
characteristics of force fields. Integration algorithms
UNIT III
Quantum Mechanics - Introduction and concepts - Semi empirical approaches - Bsis sets and
Quantum mechanical force fields.
UNIT IV
UNIT V
Quantitative structure activity relationships - Applications in drug discovery - Software tools for
QSAR - An overview of common descriptors- Interpretation of results.
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Reference books:
MICROBIOLOGY
IMMUNOLOGY
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CORE COURSE XIV - PRACTICAL IV
Programming in C :
DBMS :
19
ELECTIVE COURSE I - BIOTECHNIQUES
UNIT I
Principles and applications of Microscopy – light and electron microscope – sample preparation
for microscopy – Fixatives and Fixation – Microtome and Sectioning – Stains and Staining –
Mounting and Labelling.
UNIT II
UNIT III
UNIT IV
UNIT V
Principle - Working mechanism and Applications of X ray diffraction, Mass, NMR and ESR
Spectroscopy.
Reference Books:
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ELECTIVE COURSE II - GENETICS AND EVOLUTION
UNIT 1
Principle and laws of Mendelian inheritance – Genetic interactions – Multiple alleles – Sex
determination – Sex limited and sex-linked inheritance – Non disjunction.
UNIT II
Modern concepts of Pro and Eukaryotic genes – Regulation of gene expression – Lac and Trp
Operon - Chromosome mapping: Linkage and Genetic mapping – Estimation of map distance.
UNIT III
Human Genetics: Gene (point) mutation – Mutagens – Teratogens & Induced birth defects – In
born errors of metabolism – Human Karyotype, Chromosomal variations and syndromes in man.
UNIT IV
Origin of life: Molecular evolution – Concepts and theories of Organic evolution – Mechanisms
producing genetic diversity – Phylogenetics using Morphometric, biochemical and molecular
tools.
UNIT V
Text Books
1. Veer Bala Rostogi -A textbook of Genetics, Kedar Nath Ram Nath, Meerut, 1992.
2. P.S. Verma and V.K. Agarwal, Genetics, S.Chand and co.Ltd. New delhi, 2001.
3. P.S. Verma and V.K. Agarwal, Concept of evolution, S.Chand & Company Ltd., 1998.
4. Veer Bala Rostogi, Evolution.
Reference Books
1. Robert H.Tamarin, Principle of Genetics, The McGraw Hill companies, Inc., 1999.
2. P.K. Gupta, Genetics, Rostogi publications, 1997.
2. Strickberger Manroe, W., Genetics, Jones & Barlett Publishers, 1996.
3. Karvita B. Ahluwalia, Genetics, New age International (P) Ltd., 1996.
4. Strickberger, M.W, Evolution, Jones & Barlett Publishers, 1996.
5. Edwin H Colbert, Evolution of the Vertebrates.
6. R.A. Raff, T.C. Kaufman, Embryos, Genes, and Evolution, Macmillan Publishing Co., Inc.,
1983.
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B.Sc. Informatics
ELECTIVE COURSE III - BIOPHYSICAL SCIENCES
UNIT I
UNIT II
UNIT III
Energy pathways in Biology: – Free energy – Coupled reactions – Group transfer potential –
Role of pyrimidine Nucleotides – Photosynthesis – Energy conversion pathways – Membrane
transport.
UNIT IV
UNIT V
Textbook:
1. Vasantha pattabhi and N. Gautham, Biophysics, Narosa publishing house, 2002. (For all
units)
Reference book:
1. Rodney Cotterill, Biophysics An Introduction, John Wiley & Sons, Ltd., 2002.
2. Daniel M., Basic Biophysics for Biologists. Wiley International, New Delhi, 1992.
3. Ackerman E., Biophysical science, Prentice Hall, New Delhi, 1962.
4. Das D., Biophysics and Biological chemistry, Academic Publishers,
Calcutta, 1996
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ELECTIVE COURSE – IV COMPUTER AND ITS APPLICATION IN BIOLOGY
UNIT I
UNIT II
Number system – Operating system - Memory organization: Basic memory cell, RAM, ROM,
DRAM, main memory, auxiliary memory, associative memory, cache memory, virtual memory –
Input Output devices.
UNIT III
Computer software: Languages – Source and Object program – Translators – Utilities and
Packages – Applications of BASIC, FORTRAN, COBAL, PASCAL, C.PROLOG, LOGO and
PL/1.
UNIT IV
UNIT V
Information Retrieval: Information systems, Internet basics, Information access, LAN, WAN,
WWW, NICNET, ERNET, VSNL, ISDN.
Reference Books:
*****
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*******
I Language Course – III (LC) 6 4 3 100
II English Language Course – III (ELC) 6 4 3 100
III Core Course – IV (CC) – Physiology and 6 4 3 100
Biochemistry
Core Course V- Practical II: Physiology & 4 - - -
Biochemistry
III Second Allied Course – I (AC) – Physical 5 3 3 100
and Inorganic chemistry
Second Allied Course – II (AC) – Organic 3 - - -
chemistry
Total 30 15
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III YEAR (V & VI SEMESTER)
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