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300 Signs and Symptoms • Hyperprolactinemia (elevated prolactin

of Celiac Disease (adults hormone)

• Hypoprothrombinemia
and children) • Idiopathic Thrombocytopenic Purpura
MARCH 19, 2015 ~ ONEDISH2010 • Liver Enzymes, Elevated
• Macroamylasemia
300 Signs, Symptoms, Associated
• Macrocytosis
Disorders/Complications directly or
• Macrolipasemia
indirectly, resulting from celiac disease
• Magnesium, Low
and gluten sensitivity.
• Neutropenia
• Phosphorus, Low
Source: Cleo J. Libonati, RN,
• Plasma Proteins, Low
BSN, Recognizing Celiac Disease. “This
• Potassium, Low
list is now being used by celiac disease
• Prolonged Prothrombin Time
centers, national celiac organizations
• Transient Erythroblastopenia
and health organizations worldwide”.
• Zinc, Low
Blood System Symptoms
Body Composition Symptoms
Abnormal levels of blood components
Disorders of the body as a whole.
and quality of blood cells and plasma,
• Anorexia (Poor appetite)
detected by blood studies ordered by a
• Appetite, Increased
• Cachexia (Wasting of the body)
• Anemia, Folic acid
• Loss of Vitality
• Anemia, Iron
• Obesity
• Anemia, Vitamin B12
• Weight Gain, Unexplained
• Anti-Endomysium Antibodies (EMA)
• Weight Loss, Unexplained
• Anti-Gliadin Antibodies (AGA)
Cardiovascular System Symptoms
• Anti-Tissue Transglutaminase
Disorders of the heart and blood vessels.
Antibodies (tTG)
• Angina Pectoris
• Associated Autoimmune Antibodies
• Aortic Vasculitis
• Bone Alkaline Phosphatase Enzyme,
• Atherosclerosis
• Cardiomegaly
• Calcium, Low
• Coronary Artery Disease
• Cholesterol, Low (below 156)
• Easy Bruising (Ecchymosis)
• Coagulation Factors, Low
• Hypertension
• Copper, Low
• Idiopathic Dilated Cardiomyopathy
• Hemochromatosis
• Nosebleeds, Unexplained
• Glucose, Low or elevated
Digestive System Symptoms
• Homocysteine, Elevated
The following symptoms in this section
may be present alone or in any • Diarrhea, acute (Also called celiac
combination in celiac disease. They crisis)
result from inflammation, damage,and • Diarrhea, chronic
interference with normal function • Duodenal Erosions in the Second Part
caused by gluten exposure in the of Duodenum (Small ulcers)
digestive tract itself and/or nutritional • Dysphagia (Difficulty swallowing)
deficiencies. As you see, problems can • Edema of Small Intestinal Lining
develop not only in the small intestine • Esophageal Small Cell Cancer
where inflammation can be intense, but • Esophageal Motor Abnormalities (Poor
also in other areas such as mucosal muscle activity/coordination)
tissues of the mouth, esophagus, • Gas
stomach and colon. • Gastric Ulcer (Stomach ulcers)
• Abdominal Distention (Bloating) • Gastric Ulcerations
• Abdominal Pain • Gastritis, Collagenous
• Adenocarcinoma of the Small Intestine • Gastritis, Lymphocytic
• Aphthous Ulcers (Canker sores in • Gastro-Esophageal Reflux Disease
mouth) (GERD)
• Autoimmune Cholangitis • Gastro-Intestinal Occult Bleeding
• Beta Casein Enteropathy (Cow’s dairy (Blood in stool that is not visible to
intolerance similar to celiac disease) naked eye)
• Bleeding, Unexplained • Gluten Sensitive Enteritis
• Cancer of the Esophagus • Gums bleeding/ swollen (Purplish in
• Cancer of the Pharynx adults/ red in children)
• Candida Infections • Heartburn
• Carbohydrate Malabsorption • H. Pylori Bacter (Infection of the
• Cheilosis (Red lips, cracking/ oozing at stomach)
corners of mouth) • Impaired Gall Bladder Motility
• Colitis, Collagenous • Irritable Bowel Syndrome
• Colitis, Lymphocytic • Jejunitis, chronic
• Colitis, Ulcerative • Lactose Intolerance (Gas, bloating,
• Colonic Volvulus (Loop of intestine loose stools from milk)
twists causing strangulation of intestine) • Laryngospasm
• Constipation • Leaky Gut Syndrome
• Constipation Alternating with Diarrhea • Lymphoma
• Crohn’s Disease • Malabsorption of Nutrients
• Defective Tooth Enamel (Yellow, white • Maltose Intolerance (Gas, bloating,
spots, missing enamel) loose stools from maltose, a simple
• Delayed Gastric Emptying (Early carbohydrate)
fullness after eating) 2
• Nausea • Primary Hyperparathyroidism
• Oral Mucosal Lesions (Mouth lesions) • Secondary Hypoparathyroidism
• Plummer-Vinson Syndrome Immune System Symptoms
• Post-cricoid Cancer Disorders of antibody production.
• Primary Biliary Cirrhosis (Bile backs up • Allergic Rhinitis
in liver) • Antiphospholipid Syndrome
• Primary Sclerosing Cholangitis • Asthma
(Scarring of bile ducts in liver) • Autoimmune Disorders in Celiac
• Small Bowel Intussusception (One loop Disease
of intestine slips into another) • Autoimmune Disorders in Dermatitis
• Small Intestinal Bacterial Overgrowth Herpetiformis
• Steatorrhea (Pale, smelly, floating • Autoimmune Polyglandular Syndromes
stool hard to flush or sticks to toilet) • Common Variable Immunodeficiency
• Sucrose Intolerance (Gas, bloating, • Food Allergies, IgE and non-IgE
mucous in stool from sugar) Immune Responses
• Tongue (Beefy, red, smooth, burning) • IgA Deficiency
• Tongue (Fiery red, smooth, swollen, • Sarcoidosis
sore) • Sjögrens Syndrome
• Tongue (Magenta, swollen) • Systemic Lupus Erythematosus
• Tongue (Pale, smooth, burning) • Urticaria, chronic (Hives)
• Vomiting Integumentary System Symptoms
Glandular System Symptoms Disorders of skin, hair, and nails.
Disorders of the glands. • Alopecia Areata (Patches of hair loss)
• Addison’s Disease (Adrenal gland • Alopecia, Diffuse (Balding)
failure) • Cutaneous Vasculitis
• Autoimmune Hepatitis • Cutis Laxa
• Autoimmune Thyroiditis • Dermatitis Herpetiformis
(Hypothyroidism) • Dermatomyositis
• Diabetes Mellitus Type I • Eczema
• Diabetic Instability • Edema (Swelling)
• Gastro-Intestinal Complications of Type • Eythema Elevatum Diutinum
1 Diabetes • Erythema Nodosum
• Grave’s Disease (Hyperthyroidism) • Follicular Hyperkeratosis (Dry rough
• Hepatic Granulomatous Disease skin/ plugged hair follicles on body)
• Idiopathic Hypoparathyroidism • Ichthyosis, Acquired
• Non-Alcoholic Fatty Liver Disease • Itchy Skin Rash
• Pancreatic Insufficiency • Hangnail
• Parathyroid Carcinoma • Koilonychia (Thin nails that flatten,
ends progressively turning up instead of • Muscle Spasm and Cramps
down) • Muscle Wasting
• Melanoma • Muscle Weakness
• Nails, Dry and brittle that chip, peel, • Osteomalacic Myopathy
crack or break easily • Polymyositis
• Nails with Horizontal and Vertical • Tetany
Ridges/Fragile Nervous System Symptoms
• Nail with Rounded and Curved Down Disorders of nerves, brain and spinal
Ends, Dark, Dry cord structure and function.
• Nails with White Spots • Anxiety
• Nails with Splinter Hemorrhages • Apathy
• Pityriasis Rubra Pilaris • Ataxia, Gait Disturbance
• Prurigo Nodularis (Hyde’s Prurigo) • Ataxia, Gluten
• Psoriasis • Ataxia, Progressive Myoclonic
• Scleroderma • Brain Atrophy
• Seborrhea • Cerebral Perfusion Abnormalities (Poor
• Thin hair blood flow)
• Vitiligo • Chonic Fatigue Syndrome
Lymphatic System Symptoms • Chorea
Disorders of the lymphocytes (white • Cortical Calcifying Angiomatosis
blood cells), lymph nodes and spleen. • Dementia
• B-cell non-Hodgkin’s Lymphoma • Depression
• Cryptic Intestinal T-cell Lymphoma • Epilepsy
(Refractory Sprue) • Fatigue/ Lassitude
• Enteropathy Associated T-cell • Headache
Lymphoma (EATL) • Inability to Concentrate
• Extraintestinal Lymphomas • Insomnia
• Intraepithelial Lymphocytosis in Small • Irritability
Bowel Samples • Migraine
• Lymphadenopathy • Multiple Sclerosis
• Mesenteric Lymph Node Cavitation • Nervous System Disorders
• Hyposplenism (Atrophy of spleen) • Peripheral Neuropathy
Muscular System Symptoms • Progressive Multifocal
Disorders of muscle structure and Leukoencephalopathy
function. • Schizophrenic Spectrum Disorders
• Hypokalemic Rhabdomyolysis (Acute, • Tremors
severe potassium deficiency) • Vasculitis of the Central Nervous
• Muscle Pain and Tenderness System
Pulmonary System Symptoms • Psoriatic Arthritis
Disorders of lung tissue and broncheal • Recurrent Monoarthritis
tree structure and function. Urinary System Symptoms
• Bronchiectasis Disorders of kidneys and urinary tract
• Bronchial Pneumonia structure and function.
• Idiopathic Pulmonary Hemosiderosis • Hypocalciuria
• Increased Pulmonary Permeability • IgA Nephropathy
• Increased Susceptibility to Tuberculosis • Kidney Stones
• Lung Cavities or Abcess • Urinary Tract Infection
• Non-Response to Tuberculosis Reproductive System Symptoms in
Treatment Females
• Pneumococcal Septicemia Disorders of organ structure and
Sensory System Symptoms function.
Disorders of sense organ structure and • Amenorrhea (Absence of menstrual
function. period)
• Bitot’s Spots (Foamy patches on • Early Menopause
whites of eye) • Infertility
• Blepharitis • Late Menarche (Late start of menstrual
• Bloodshot Eyes periods)
• Blurred Vision • Premenstrual Syndrome
• Cataracts • Dysmenorrhea (Painful menstrual
• Keratoconjunctivitis Sicca periods)
• Keratomalacia • Dyspareunia (Painful intercourse)
• Nightblindness • Vaginitis
• Ocular Myopathy Reproductive System Symptoms in
• Smell, Loss of Males
• Taste, Loss of Disorders of organ structure and
• Uveitis, Bilateral function.
• Xerophthalmia • Hypogonadism
Skeletal System Symptoms • Impotence
Disorders of bone, joints and teeth. • Infertility
• Bone Fracture • Sperm Abnormalities
• Bone Pain Reproduction: Pregnancy, Labor &
• Enteropathic Arthritis Delivery and Puerperium Symptoms
• Osteitis Fibrosa Disorders of childbearing.
• Osteomalacia • Severe Iron Deficiency Anemia in
• Osteonecrosis Pregnancy
• Osteoporosis • Short Duration of Breast Feeding
• Miscarriage Small Intestine (Lack of enzymes
• Complications During Pregnancy, produced by villi)
Labor and Delivery • Penicilllin V Impaired Absorption
• Complications After Childbirth • Refractory Anemia (Unresponsive to
Zygote Development Symptoms iron therapy)
Disorders of chromosomes. • Osteopenia
• Down Syndrome • Rickets
• Turner’s Syndrome • Short Staure
Fetus Development Symptoms • Stroke in Childhood
Disorders of that occur before birth of Here are some other ways to look at
the child. various symptoms:
• Congenital Anomalies Behavioral Symptoms
• Intrauterine Growth Retardation • Aloofness
• Cystic Fibrosis • Hyperactivity
• Spina Bifida • Irritability (Common in children with
Child Development Symptoms celiac disease)
Disorders of children that occur after • Impatience
birth. • Lack of Desire to Get Things Done
• Autism and Learning Disorders • Lack of Feeling
• Attention Deficit Hyperactive Disorder • Restlessness
(ADHD) • Timid Behavior
• Cancer Predisposition in Children • Violent Behavior
• Chronic Bullous Dermatosis Neurological Issues
• Delayed Puberty in Boys • Anxiety
• Delayed Puberty in Girls • Apathy
• Dermatitis Herpetiformis • Bipolar disorder
• Developmental Delay • Depression
• Failure to Thrive and Growth • Difficulty Making Friendships
Retardation • Easy Frustration and Anger
• Fecal Occult Blood (Blood found in • Nervousness
stool that is not visible to the naked eye) • Panic Attacks
• Glycogenic Acanthosis • Sense of Worthlessness
• Hypotonia • Overly Self-critical
• Juvenile Autoimmune Thyroid Disease • Hysteria
• Juvenile Diabetes Type 1 • Hypochondria
• Juvenile Idiopathic Arthritis Cognitive (Thinking) Symptoms
• Abnormal Blood Studies • Confused/ Faulty Thinking
• Latent Anemia in Enzymopathies of • Confabulation
• Delusions
• Dementia
• Disorientation
• Faulty Learning
• Hallucination
• Inattentiveness
• Loss of Memory
• Loss of Immediate Memory
• Poor Memory
• Reduced Learning
• Slow Thinking
• Scattered Thinkin