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Received: 10 April 2018 Revised: 30 June 2018 Accepted: 6 August 2018

DOI: 10.1002/cpp.2322

RESEARCHARTICLE

Exploration of the dialogue components in Avatar Therapy


for schizophrenia patients with refractory auditory
hallucinations: A content analysis
1,2,3 1,2,3 4
Laura Dellazizzo | Olivier Percie du Sert | Kingsada Phraxayavong |
1,2 1,2 1,2,3,4
Stéphane Potvin | Kieron O'Connor | Alexandre Dumais

1Research Center of the Institut Universitaire


en Santé Mentale de Montréal, Montreal, Abstract
Canada
Auditory verbal hallucinations are hallmark symptoms of schizophrenia and are amongst
2Department of Psychiatry and addictology,
Faculty of Medicine, Université de Montréal, the most disturbing symptoms of the disorder. Although not entirely under-stood, the
Montreal, Canada
relationship between the voice hearer and their voices has been shown to be an
3Institut Philippe‐Pinel de Montréal,
Montreal, Canada important treatment target. Understanding voice hearers' standpoints through qualitative
4Services et Recherches Psychiatriques analysis is central to apprehend a deeper comprehension of their experi-ence and
AD, Montreal, Canada
Correspondence further explore the relevance of interpersonal interventions. Compared with other
Alexandre Dumais, Institut Philippe‐Pinel de dialogical intervention, virtual reality‐assisted therapy (Avatar Therapy) enables patients
Montréal, Montreal, QC H1C 1H1, Canada.
Email: alexandre.dumais@umontreal.ca
to be in a tangible relation with a representation of their persecutory voice. This novel
Funding information therapy has shown favourable results, though the therapeutic processes remain
Applications de la Réalité Virtuelle en equivocal. We consequently sought to begin by characterizing the main themes
Psychiatrie Légale; Services et Recherches
Psychiatriques AD; Eli Lilly Canada Chair on
emerging during the therapy by exploring the hearer's discussion with their avatar. The
schizophrenia research; Fondation Jean‐Louis therapy sessions of 12 of our referrals were transcribed, and the patients' responses
Lévesque; Institut Philippe‐Pinel Foundation
were analysed using content analysis methods. Five themes emerged from data
saturation: emotional responses to the voices, beliefs about voices and schizophrenia,
self‐perceptions, coping mechanisms, and aspirations. All patients had at least one
element within each of these themes. Our analyses also enabled us to identify changes
that were either verbalized by the patients or noted by the raters throughout therapy
sessions. These findings are relevant as they allowed to identify key themes that are
hypothesized to be related to therapeutic targets in a novel relational therapy using
virtual reality. Future studies to further explore the processes implicated within Avatar
Therapy are necessary.

KEY W ORDS

auditory verbal hallucinations, Avatar Therapy, dialogical approach, qualitative content


analysis, schizophrenia

| characteristics of speech and may frequently be personified (David,


1 I N T RO D U CT I O N
2004). AVH have also been shown to be associated with psychological
Auditory verbal hallucinations (AVH) remain hallmark symptoms of distress (Birchwood & Chadwick, 1997). Despite the efficacy of
schizophrenia and are amongst the most disturbing symptoms in pharmacological treatments, approximately 30% of patients diagnosed
schizophrenia (David, 1999; Sartorius et al., 1986; Sommer et al., with schizophrenia are treatment‐resistant (TRS) and experience per-
2012). AVH are quite heterogeneous; they have differing sistent AVH (Elkis, 2007). Moreover, psychotherapeutic alternatives,

Clin Psychol Psychother. 2018;1–8. wileyonlinelibrary.com/journal/cpp © 2018 John Wiley & Sons, Ltd.
1
2 DELLAZIZZO L. ET AL.

such as cognitive behavioural therapy, are only moderately effective


(Jauhar et al., 2014). The hearing voices movement advocates that
Key Practitioner Message
understanding the perspective of voice hearers and developing a
framework for them to attribute meaning to their voices are essential • Understanding voice hearers' experience is central to
(Lakeman, 2001; Romme & Escher, 1989). Within this perspective, ensure that clinical practice and research is in
current advances in literature have shown the importance of the alignment with their views.

relationship between the hearer and the voice (Hayward, Berry, & • Although Avatar Therapy has shown promising results
Ashton, 2011). Hence, understanding voice hearers' standpoints is for patients with treatment resistance, the therapeutic
central to ensure that clinical practice and research is in alignment with processes of this dialogical intervention remain
their views (Balaji et al., 2012; Schizophrenia Commission, 2012). equivocal.
Qualitative research provides service users a chance to contribute
• The main themes that emerged from the transcripts of
experientially in health care by documenting their experiences, priorities,
our patients while in discussion with a representation
meanings, and preferences (Evans, 2002). Yet, it may be underused. In
of their most disturbing voice were emotional response
the context of mental health, qualitative analysis (such as content
to voices, beliefs about voices and schizophrenia, self‐
analysis) is potentially useful as it can offer new insights on poorly
perceptions, coping mechanisms, and aspirations.
understood areas, such as understanding the subjective experiences of
patients with schizophrenia (Crowe, Inder, & Porter, 2015; Fossey,
• This analysis provided further knowledge into the
Harvey, McDermott, & Davidson, 2002). Unlike quantitative analyses that
hallucinatory experience and enabled to identify
reduce data into easily comprehensible components and risk in putting
themes that may relate to important therapeutic targets
individuals into a predetermined framework (Whitley & Crawford, 2005;
for voice hearers.
Yardley, 2000), qualitative analyses allow to capture the richness of
individual accounts (Whitley

& Crawford, 2005). As used within research, this procedure may be


extended across different experiential descriptions obtained from relationship with their voices (Birchwood, Meaden, Trower, & Gilbert,
patients to develop a wider comprehension of the experience itself 2002; Chadwick, 2006; Hayward, 2003; Hayward & Fuller, 2010;
(Crowe et al., 2015). For an example of its utility in schizophrenia, it Leudar et al., 1997).
has been used to explore treatment outcomes that caregivers Yet, these dialogical interventions have not enabled patients to be in
considered important for those diagnosed with schizophrenia such a more tangible relation with their persecutory voices. To overcome this
as symptom‐related outcomes, functional outcomes, personal issue, Leff, Williams, Huckvale, Arbuthnot, and Leff (2013) devel-oped a
recovery, quality of life, and satisfaction with treatment (Lloyd, Lloyd, therapy (Avatar Therapy (AT)) using a computerized system that permits
Fitzpatrick, & Peters, 2017). voice hearers to create a visual representation, that is, an avatar, of their
Notably, preliminary qualitative analyses have shown to be valuable persecutor. Patients were prompted to engage in a dialogue with their
to apprehend a deeper understanding of voice hearers' experiences and avatar animated by the therapist. The therapeutic objective was to help
further explore the relevance of interpersonal theories on AVH (Mawson, voice hearers gain control over their symptoms. AT has shown
Berry, Murray, & Hayward, 2011). Such qualitative research has found favourable results on AVH (Craig et al., 2018; Leff et al., 2013). Rather
that people who hear voices personi-fied them and searched for than using conventional computerized technology, our research team
explanations about these experiences (Mawson et al., 2011). independently adapted AT using immersive virtual real-ity and compared,
Furthermore, increased distress has been seen in those that feared their in a pilot randomised controlled trial, AT to treat-ment as usual in patients
voices and perceived a lack of control within this relationship (Birchwood with TRS (du Sert et al., 2018). We found significant improvements in
& Chadwick, 1997; Johns, Hemsley, & Kuipers, 2002; Nayani & David, AVH severity as well as in beliefs of malevolence, depressive symptoms,
1996). This knowledge brought insight into how individuals employed and quality of life, which lasted at the 3‐month follow‐up.
coping strategies to manage their voices (Mawson et al., 2011). Notwithstanding, the therapeutic processes of this novel dialogical
Interventions focusing on psychological processes that may be intervention remain equivocal.
associated with distress related to voices, such as interpersonal relating In this vein, as a first step towards future studies aimed
(i.e., Relating Therapy [Hayward, Overton, Dorey, & Denney, 2009],
at inves-tigating more profoundly the therapeutic processes
Cognitive Behavioural Relating Therapy [Paulik, Hayward, & Birchwood,
2013], or Dialogical Therapy [Leudar, Thomas, McNally, & Glinski, of AT, we sought to characterize the main themes that
1997]), are likely to be very promising (Thomas et al., 2014). These emerged from the therapy ses-sion transcripts of 12 of our
approaches, associated with improved coping and reduced distress, aim
patients with TRS while discussing with a virtual
to ameliorate the hearer–voice relationship by encouraging an assertive
engagement with voices (i.e., determine their intent and meaning) and by representation of their most disturbing voice. We used one
negotiating new ways of relating (Jackson, Hayward, & Cooke, 2011). All of the most extensively used analytical method for
in all, this dialogical process has been found to improve over time voice
qualitative research (qualitative content analysis), which
hearers' views of themselves and allow them to achieve a more
constructive may be used in all types of written texts (Elo & Kyngäs,
2008). Content analysis is a research method for making
replicable and valid inferences from data to their context,
with the purpose of providing knowledge, new insights, a
rep-resentation of experience, and a practical guide to
significant themes (Krippendorff, 2012).
DELLAZIZZO L. ET AL. 3

| TABLE 1 Sociodemographic and clinical characteristics of the


2 METHOD
sample

| n = 12
2.1 Participants
Sociodemographics
Participants in the current study comprised the first 12 consecutive Gender
referrals having received and completed their seven weekly sessions of Male 7 (58.3)
AT in a proof‐of‐concept clinical trial recently conducted by our research Female 5 (41.7)
team (see [du Sert et al., 2018]). Patients (≥18 years old) with refractory Age 45.4 (12.2)
AVH and schizophrenia or schizoaffective disorder were recruited from Ethnicity
the Institut Universitaire en Santé Mentale de Montréal (where the Caucasian 10 (83.3)
therapy was likewise provided) as well as from the commu-nity. Patients Other minority 2 (16.7)
were recruited if they had been hearing persecutory voices and did not Language
respond to at least two antipsychotic trials. Exclusion criteria included (a) French 11 (91.7)
any change in medication in the past two months; (b) the presence of a English 1 (8.3)
concomitant substance use disorder in the last 12 months, a neurological Civil status
disorder or an unstable and serious physical illness; (c) a highly unstable Single 9 (75.0)
state (e.g., currently in psychiatric intensive care unit); and (d) having Divorced/Separated 2 (16.7)
followed CBT for psychosis in the last 12 months. Ethical approval was Married/Common in law 1 (8.3)
obtained from the local ethics committee, and all participants gave their Level of schooling (years) 13.9 (4.8)
informed consent. Sociodemographic and clinical information on the Employment status
sample of this study are presented in Table 1. Unemployed 8 (66.7)
Employed 1 (8.3)
Retired 3 (25.0)
| Clinical
2.2 Avatar Therapy
Diagnosis
AT is a seven‐week intervention where the therapist engaged in a dia-
Schizophrenia 10 (83.3)
logue with patients through a virtual representation (i.e., avatar) of their
Schizoaffective disorder 2 (16.7)
most distressing voice. See du Sert et al. (2018) for more details. The
Duration of illness (years) 17.5 (5.0)
created avatar was designed to closely resemble both the face and the
Total PANSS score 77.1 (13.8)
voice of their persecutor. In the early sessions, emotional reg-ulation was
Antipsychotic medication
challenged with the help of sentences used by their perse-cutor.
Typical 3 (25.0)
Thereafter, self‐esteem was addressed by enabling the patients to
Atypical 11 (91.7)
consider their personal qualities. In the final consolidation sessions,
patients practised self‐assertive statements and strategies to reply to Clozapine 6 (50.0)
their voices by applying what they had previously learned.
Note. PANSS: positive and negative syndrome scale. n (%) or mean (SD).
The therapy was delivered in French for all patients except for
one, which was delivered in English, by a trained therapist (A. D.)
who has five years of experience in the treatment of schizophrenia.
removed. Therefore, only the patients' thoughts were maintained. As
The length of each AT sessions ranged from 3.22 to 24.31 min with
many transcripts as necessary were analysed until the achievement
a mean duration of 10.84 min (SD = 4.64). All AT sessions were
of a saturation point where no new themes or categories emerged
audio recorded and transcribed by a professional transcriber. French
from the data.
excerpts were then translated into English.
First, O. P., S. P., and K. O. each read through the transcripts of the
seven sessions of the first three patients (21 transcripts). As many
|
2.3 Analytical procedure headings as necessary were systematically written down to describe all
Qualitative content analysis was conducted following the procedures aspects of the dialogue. Individually, the headings were collected,
described by Zhang and Wildemuth (2016). Content analysis enables the categorized into related concepts, and then grouped under higher order
interpretation of verbal communications through the systematic themes to develop integrated explanatory representations of the data.
classification process of coding and identifying themes or patterns (Hsieh Analyses were compared between authors and discrepancies were
& Shannon, 2005). The unit of analysis was defined as a word or a group discussed until a first consensus was attained.
of words that could fall under a specific theme. The process of identifying Second, a preliminary coding scheme with a description
themes and categories was inductive and iterative.
of themes was developed to standardize the categorization
Of interest in this study, only the patients' words were considered for
analysis, whereas the therapist's/the avatar's utterances were left out of of excerpts between the three evaluators. This coding
the analysis. Furthermore, any sentences that were ambiguous or direct
procedure was then tested on the transcripts of the
repetitions of the therapist's/the avatar's dialogue were
sessions of six patients (42 transcripts) to help reveal
inconsistencies and inadequacies in the initial categorical
construction. During this process, some
themes/subcategories were redefined, and
4 DELLAZIZZO L. ET AL.

some arose or were dropped out based on the frequency within and haven't heard you.” P7 “I won't get angry, not this
across the transcripts of all seven sessions. time, I'm feeling peaceful.” P7 “Those days, your
Third, the coding scheme with our defined themes was modified voice does not intimidate me so much.”
and further elaborated with instructions for describing each theme as
well as examples and quotes to resolves ambiguities. An indepen- Theme II. Beliefs about voices and schizophrenia
dent audit was carried out by LD following this coding scheme to
examine the coherence of the analysis and the grounding of A recurrent theme appeared to be the patients' on‐going
interpre-tations from the data (Lincoln & Guba, 1985). struggles with their mental health and their insight into their illness.
Fourth, an agreement between all authors was systematically These included the patients' thoughts, beliefs, and reasoning about
sought resulting in a consensus. Following this consensus, the their voices, regarding the origin, controllability, power, and meaning
definitive themes and coding rules were applied to the transcripts of of the voices.

new patients until a saturation point was achieved where analysing Initially, many patients expressed beliefs of omnipotence and
more transcripts did not provide any new data. This step included uncontrollability.
the analysis of another six patients (42 transcripts). In total, 84
transcripts (12 patients × 7 therapy sessions) were required to reach P6 “Him, it's the illness. The illness is stronger than me. I

a saturation point. can confront him, but the illness will always be stronger
than a human being. We are ill until our death, and then
we die from the illness. The illness is the strongest.” P1
|
3 RESULTS “You are way stronger than me. You're a God, I can't
really escape from this.” P5 “You always have control
Throughout AT, the patients interacted with a visual representation of
over me, I think.” P7 “It's been years I hear you, so I
their most distressing voice. As for our 12 patients, five patients
don't think anything will change anymore.”
interacted with a demon or an evil spirit, whereas seven patients
dialogued with someone they personally knew (i.e., father, uncle,
However, more nuanced beliefs were observed throughout the
lover, neighbour, and social worker). Amongst them, three were
therapy. For instance, some patients acknowledged that their voices
females and nine were males. All voices were depicted as being
might reflect their own thoughts, whereas other adopted a perspec-
persecuting, commanding, and distressing.
tive in which voices became less powerful.
Five themes emerged from patients' responses in a dialogue
with the virtual representation of their voice in this content analysis. P1 “Maybe it's coming from me and you are saying
An important dimension observed in the verbatim during the therapy what I think of myself.” P8 “Finally, you're like my
was change. The findings will be discussed here with descriptions alter ego.” P8 “You're part of me.” P7 “I don't think
supported by patients' excerpts. you can kill me, because you're not an actual
person.” P7 “I don't believe you're an actual person,
Theme I. Emotional response to voices you're just a schizophrenic voice that I hear.” P6
“You don't have any power on me, not anymore.”
This first theme arose from the emotions that patients
experienced in response to their avatar and, by extension, to their Theme III. Self‐perceptions
voice. These emotional responses included a wide range of
emotions, positive or negative, with varying levels of intensity.
This theme comprised the patients' observations and views of
Emotions could either be explicitly expressed or an expression with
themselves, what they thought to be their strengths and
emotional content.
weaknesses. It also included reflections about their own functioning,
In the transcripts from the early sessions, most participants related
their behav-iours, their emotions, and their thoughts.
to their avatar with fear, anger, or sadness. Some patients were so
It was commonly seen at first that most patients adopted a self‐
intimidated by the avatar that they would remain silent or speak with a
condemning position, including many negative beliefs about them-
soft voice. In contrast, other patients would become angry.
selves. Those beliefs mostly concerned their personal qualities and
their life achievements.
P1 “I don't know what to answer, you really scare me.”
P2 “You're making me mad with all of your foolishness.”
P8 “I don't like myself, I'm always negative towards
P3 “My heart is shaking.” P4 “I'm so fed up with you.” P5
myself, I blame myself for nothing then I pull out my
“I'm crying every night because I'm sick of hearing you.”
hair.” P8 “I have failed in life, I don't work, I receive
P6 “I don't feel good, I suffer a lot.”
social aid, so when I hear such qualities, it feels weird,
because I don't have any.” P3 “I'm incompetent.”
As the therapy progressed, patients reported having a better
grasp over those feelings
Though, while interacting with the avatar, some participants
P3 “I'm not afraid of you anymore, I'm not scared to were able to show their self‐confidence by reasoning with
confront you.” P7 “Now I feel good, it's been a while I concrete examples.
DELLAZIZZO L. ET AL. 5

P3 “I started at the very bottom and I moved up to P5 “I'm going to try and stay busy to avoid hearing you.”
become manager. It's not the first time I do this. For P7 “I'm trying to go out a little bit more.” P7 “When I hear
sure I'm a hard worker.” P9 “I give to homeless voices and it's really not going well, I take my meds.”
people, I volunteer, I know I'm a good person.” P11 “I could do art.” P3 “Work is health. I'm trying to go
out more often and take some walks.”
During the therapy, many patients talked about changes in their
views of themselves, which could be empowering and allowed them Theme V. Aspirations
to build a better self‐image.
Patients often expressed to their avatar their will for the future
P4 “I'm discovering what my qualities are.” P10 “In with a request, a task or an order. These desires revolved notably
my life, I always struggled to accept a compliment, around sending the avatar away or setting limits as well as
but today I take them for what they are. I can see demanding control and answers. Patients could be assertive in
that I have qualities.” P8 “Now I believe in myself, I different fashions when expressing those demands.
have a high esteem and I love myself the way I am,
with my strengths and weaknesses.” P6 “If I wouldn't
P1 “I don't want you to talk to me, I don't want to hear
have worked on my self‐esteem, I wouldn't have
you, I don't want to listen to you, I don't want to feel you,
confronted you today.” P10 “Now, I have developed
I don't want to have anything to do with you.” P9 “I want
strengths to push you away.”
you to leave, I want you to stop bothering me.” P6 “I
want to make peace with you.” P8 “I would like you to be
Theme IV. Coping mechanisms
less negative towards me.” P3 “Why are you after me?”
This theme included all the techniques used by the patients to P7 “Why, what have I done to you?” P1 “I don't want you
deal with their avatar and extensively with their voices. These to tell me to hurt anybody.”
approaches included strategies that were used beforehand and
those learnt with the help of the therapy. This theme was further
subdivided into three subcategories.
|
4 DISCUSSION
a. Affective strategies required patients to actively try to manage
their emotions when interacting with their avatar. Mostly, patients This study is to our knowledge the first to qualitatively examine the
tried to remain calm by appealing to peaceful and positive experiences of patients with TRS while conversing with a
feelings. representa-tion (avatar) of their most disturbing voice during the
sessions of a new dialogical intervention, that is, AT. Following the
discussion between voice hearer and their avatar animated by the
P7 “I'm calmer, I'm trying to be less aggressive.” P7
therapist, we collected the verbatim of the therapeutic sessions of 12
“I'm trying to talk to you without getting upset, without
patients with TRS having completed the seven sessions of AT. Five
getting mad, like we are doing right now. It's going to
general themes emerged from data saturation using content
be okay” P7 “I ease myself while talking to you, I
analysis methods: emotional responses to the voices, beliefs about
don't need to get angry.” P3 “I reassure myself.” P6 “I
voices and schizophrenia, self‐perceptions, coping mechanisms,
don't let myself be intimidated”
and aspira-tions. Although the excerpts were distinct from patient to
patient, they had at least one element within each of these themes.
b. Cognitive strategies involved rational thinking, attempts to ignore
the avatar or shifting attention to concentre on another subject Our analysis enabled in the development of a coding scheme
and control their thoughts. These thoughts were actively put in with themes that may relate to important therapeutic targets for
place to cope with their avatar or their voices when they would voice hearers. As such, findings from this study provide further
occur. knowledge into the hallucinatory experience of those with distressing
voices within a relational and therapeutic framework following AT.
P5 “I'm going to try to block my head and block my Although this was not a phenomenological analysis, we observed
thoughts to not hear you anymore.” P3 “I'm trying to certain components that help to understand the hallucinatory
stop believing you.” P10 “You're not my father. A experience of patients that are consistent with past research
father wouldn't do that to his daughter. You won't outlining the key therapeutic targets in psychological inter-ventions
control me anymore.” P6 “I'm trying to ignore you, for voice hearers (Chadwick, 2006; Hayward, 2003; Jackson et al.,
but it doesn't work.” P1 “Meditation works fine, I think 2011; Mawson et al., 2011; Thomas et al., 2014). Our analysis
about positive things.” P3 “I need to let it go, you're highlights that emotion regulation and self‐perceptions
are key
not important, you're just a voice.” com-ponents of the hallucinatory experience. For hearers
with distressing voices, the hallucinatory experience is
c. Behavioural strategies consisted in getting involved in any activi- associated with strong negative emotions such as fear,
ties that could help the patients deal with their voices. anger, and sadness. The distress associated with AVH is
such a concern for voice hearers that it is
6 DELLAZIZZO L. ET AL.

the most widely studied therapeutic outcome for this population in excluded excerpts that the patients repeated following the thera-
psychological interventions (Johns et al., 2014). It was thus pist's dialogue, patients' speech may have been likewise influenced
expected that patients would verbalize their emotions during AT. by the content of the therapy as sessions progressed. For instance,
Perhaps more interestingly, a pertinent finding was the theme more negative emotions may have emerged throughout the initial
related to self‐perceptions. Disturbances in self‐experience has sessions, whereas a reflection of their qualities may have emerged
been shown to represent practical targets in voice hearers towards the end of the intervention.
(McCarthy‐Jones, Marriott, Knowles, Rowse, & Thompson, 2013).
Self‐concept compo-nents have been linked to voice content,
appraisals of power as well as emotional (e.g., distress) and
|
5 CO NC LUSIO N
behavioural responses to voices (Fielding‐Smith et al., 2015).
Moreover, besides the patients' self‐ perceptions, the way they Content analysis of the verbatim of our patients who completed

perceive their voices plays a role on their emotions and felt distress seven sessions of AT allowed in the identification of relevant themes

(Chadwick & Birchwood, 1994; Mawson, Cohen, & Berry, 2010). The that are hypothesized to be related to therapeutic targets in this

patients' perceptions about themselves and their voices are key relational therapy. Our data may provide a platform for the further

components that impact how patients will interpret, feel, and behave exploration of the nuances within each theme in order to determine

in the relationship with their voices (Birchwood, Meaden, Trower, finer subcategories, which may translate into therapeutic targets.

Gilbert, & Plaistow, 2000; Gilbert et al., 2001). This will likely This descriptive analysis of patients' content was a first step into

influence the way the voice hearer will employ coping strategies to investigating the therapeutic processes believed to be involved

adapt to their voices. When dysfunc-tional strategies are employed, within AT's sessions. Future studies to understand the processes

this may confirm the patients' beliefs about themselves and their implicated within AT are necessary. Ultimately, this analysis may

voices. This new dialogical intervention enables hearers to converse inform future studies to help carry out open interviews with voice

with their voice, and by doing so, patients may learn how to regulate hearers.

the strong negative emotions elicited by the persecutory voice, to be


more assertive and to strengthen their sense of self, which may FUNDING SOURCE
bring about change. AT allows patients to test/challenge their usual
This trial was funded by the Institut Philippe‐Pinel Foundation, the Fondation
coping mechanisms, while being encouraged to try new strategies
Jean‐Louis Lévesque, the Eli Lilly Canada Chair on schizophre-nia research,
throughout the ther-apy. Whereas our qualitative observations are
Services et Recherches Psychiatriques AD, and the Applica-tions de la
compatible with prior literature, this descriptive analysis consisted in
Réalité Virtuelle en Psychiatrie Légale laboratory.
the exploration of the patients' dialogical components involved in AT
and did not aim for a formal identification of the therapeutic
processes underlying the effi-cacy of this novel therapy. ACKNOWLEDGEMENTS

Although this study has certain implications that are worthwhile, S. P. is holder of the Eli Lilly Chair on schizophrenia research. A. D.
a few limitations must be acknowledged. Firstly, although we may is holder of a Junior 1 Young investigator from the Fonds de
hypothesize that for many patients, the emotions generated towards Recherche du Québec en Santé.
their avatar is similar to their responses towards their voices (Theme
I), we cannot stipulate for certain that this is true. Further studies are CONFLIC T OF INT E RE ST
necessary to analyse the distinctiveness between the patients'
A. D. is holder of a grant from Otsuka Pharmaceuticals. S. P. is holder or
reactions towards their avatar and their voices. Secondly, as content
coholder of grants from Otsuka and INSYS Pharmaceuticals.
analysis is not a uniform approach, it may be difficult to replicate
since the data arises from a specific context, in this case from a
sample of patients with TRS following a specific relational approach ORCID
(Elo & Kyngäs, 2008; Richards & Morse, 2012). This none-theless Laura Dellazizzo http://orcid.org/0000-0001-8262-130X
makes this type of analysis interesting and open to interpre-tation.
Content analysis may be applied to a variety of text forms; however, RE FE RE NC ES
not all forms provide the same amount of insight and depth into a Balaji, M., Chatterjee, S., Brennan, B., Rangaswamy, T., Thornicroft, G.,
problem (Elo & Kyngäs, 2008). Future studies should aim to use a & Patel, V. (2012). Outcomes that matter: A qualitative study with
less structured discussion to understand the therapeutic processes persons with schizophrenia and their primary caregivers in India.
Asian journal of psychiatry, 5(3), 258–265.
of the therapy, which will provide the opportunity to deepen the
discussion and allow for the patient to explain their per-spective. Birchwood, M., & Chadwick, P. (1997). The omnipotence of voices:
Testing the validity of a cognitive model. Psychological Medicine,
Thirdly, our data was obtained through an open discussion enacted 27(6), 1345–1353.
by the therapist animating the avatar. To gain insight into the
Birchwood, M., Meaden, A., Trower, P., & Gilbert, P. (2002). Shame,
patients' experience, we only included the excerpts of the patients humil-iation and entrapment in psychosis. A Casebook of Cognitive
that were not prompted by the therapist (via the avatar). Therapy for Psychosis, 108–131.
Nevertheless, the patients' thoughts may have been influenced both
Birchwood, M., Meaden, A., Trower, P., Gilbert, P., &
by the therapist and the content of the sessions. Even though we
Plaistow, J. (2000). The power and omnipotence of
voices: Subordination and entrapment
DELLAZIZZO L. ET AL. 7

by voices and significant others. Psychological Medicine, 30(2), 337– Jauhar, S., McKenna, P. J., Radua, J., Fung, E., Salvador, R., & Laws, K.
344. R. (2014). Cognitive‐behavioural therapy for the symptoms of
Chadwick, P. (2006). Person‐based cognitive therapy for distressing psychosis.
schizophre-nia: Systematic review and meta‐analysis with
examination of potential bias. The British Journal of Psychiatry,
John Wiley & Sons.
204(1), 20–29. https://doi.org/ 10.1192/bjp.bp.112.116285
Chadwick, P., & Birchwood, M. (1994). The omnipotence of voices. A
cognitive approach to auditory hallucinations. The British Journal of Johns, L. C., Hemsley, D., & Kuipers, E. (2002). A comparison of auditory
Psychiatry, 164(2), 190–201. https://doi.org/10.1192/bjp.164.2.190 hallucinations in a psychiatric and non‐psychiatric group. British
Journal of Clinical Psychology, 41(1), 81–86.
Craig, T. K., Rus‐Calafell, M., Ward, T., Leff, J. P., Huckvale, M., Howarth, E.,
Johns, L. C., Kompus, K., Connell, M., Humpston, C., Lincoln, T. M.,
… Garety, P. A. (2018). AVATAR therapy for auditory verbal hallucina-
Longden, E., … Larøi, F. (2014). Auditory verbal hallucinations in per-
tions in people with psychosis: A single‐blind, randomised controlled
trial. Lancet Psychiatry, 5(1), 31–40. https://doi.org/10.1016/S2215‐ sons with and without a need for care. Schizophrenia Bulletin,
0366(17)30427‐3 40(Suppl_4), S255–S264. https://doi.org/10.1093/schbul/sbu005
Krippendorff, K. (2012). Content analysis: An introduction to its methodology.
Crowe, M., Inder, M., & Porter, R. (2015). Conducting qualitative
Sage.
research in mental health: Thematic and content analyses. The
Australian and New Zealand Journal of Psychiatry, 49(7), 616–623. Lakeman, R. (2001). Making sense of the voices. International Journal of
https://doi.org/ 10.1177/0004867415582053 Nursing Studies, 38(5), 523–531.
David, A. (2004). The cognitive neuropsychiatry of auditory verbal Leff, J., Williams, G., Huckvale, M. A., Arbuthnot, M., & Leff, A. P. (2013).
hallucinations: An overview. Cognitive Neuropsychiatry, 9(1–2), 107– Computer‐assisted therapy for medication‐resistant auditory
123. hallucina-tions: Proof‐of‐concept study. The British Journal of
Psychiatry, 202, 428–433. https://doi.org/10.1192/bjp.bp.112.124883
David, A. S. (1999). Auditory hallucinations: Phenomenology, neuropsy-
chology and neuroimaging update. Acta Psychiatrica Scandinavica, Leudar, I., Thomas, P., McNally, D., & Glinski, A. (1997). What voices can
99(Suppl. 395), 95–104. do with words: Pragmatics of verbal hallucinations. Psychological
du Sert, O. P., Potvin, S., Lipp, O., Dellazizzo, L., Laurelli, M., Breton, R., Medicine, 27(4), 885–898.
… Dumais, A. (2018). Virtual reality therapy for refractory auditory Lincoln, Y. S., & Guba, E. G. (1985). Naturalistic inquiry ( ed., Vol. 75). Sage.
verbal hallucinations in schizophrenia: A pilot clinical trial. Schizo-
Lloyd, J., Lloyd, H., Fitzpatrick, R., & Peters, M. (2017). Treatment
phrenia Research, 197, 176–181. https://doi.org/10.1016/j.
outcomes in schizophrenia: Qualitative study of the views of family
schres.2018.02.031
carers. BMC Psychiatry, 17(1), 266.
Elkis, H. (2007). Treatment‐resistant schizophrenia. Psychiatric Clinics, Mawson, A., Berry, K., Murray, C., & Hayward, M. (2011). Voice hearing
30(3), 511–533.
within the context of hearers' social worlds: An interpretative phenom-
Elo, S., & Kyngäs, H. (2008). The qualitative content analysis process. enological analysis. Psychology and Psychotherapy: Theory,
Journal of Advanced Nursing, 62(1), 107–115. Research and Practice, 84(3), 256–272.
Evans, D. (2002). Database searches for qualitative research. Journal of Mawson, A., Cohen, K., & Berry, K. (2010). Reviewing evidence for the
the Medical Library Association, 90(3), 290–293. cognitive model of auditory hallucinations: The relationship between
cognitive voice appraisals and distress during psychosis. Clinical
Fielding‐Smith, S. F., Hayward, M., Strauss, C., Fowler, D., Paulik, G., &
Psychology Review, 30(2), 248–258.
Thomas, N. (2015). Bringing the “self” into focus: Conceptualising the
role of self‐experience for understanding and working with distressing McCarthy‐Jones, S., Marriott, M., Knowles, R., Rowse, G., & Thompson, A. R.
voices. Frontiers in Psychology, 6, 1129. (2013). What is psychosis? A meta‐synthesis of inductive qualitative
studies exploring the experience of psychosis. Psychosis, 5(1), 1–16.
Fossey, E., Harvey, C., McDermott, F., & Davidson, L. (2002).
Understand-ing and evaluating qualitative research. Australian and Nayani, T. H., & David, A. S. (1996). The auditory hallucination: A
New Zealand Journal of Psychiatry, 36(6), 717–732. phenom-enological survey. Psychological Medicine, 26(1), 177–189.
Gilbert, P., Birchwood, M., Gilbert, J., Trower, P., Hay, J., Murray, B., … Paulik, G., Hayward, M., & Birchwood, M. (2013). Cognitive behavioural
Miles, J. (2001). An exploration of evolved mental mechanisms for relating therapy (CBRT) for voice hearers: A case study. Behavioural
dominant and subordinate behaviour in relation to auditory hallucina- and Cognitive Psychotherapy, 41(5), 626–631.
tions in schizophrenia and critical thoughts in depression. Richards, L., & Morse, J. M. (2012). Readme first for a user's guide to
Psychological Medicine, 31(6), 1117–1127. qualitative methods. Sage.
Hayward, M. (2003). Interpersonal relating and voice hearing: To what Romme, M. A., & Escher, A. D. (1989). Hearing voices. Schizophrenia
extent does relating to the voice reflect social relating? Psychology Bulletin, 15(2), 209–216.
and Psychotherapy: Theory, Research and Practice, 76(4), 369–383.
Sartorius, N., Jablensky, A., Korten, A., Ernberg, G., Anker, M., Cooper, J. E.,
Hayward, M., Berry, K., & Ashton, A. (2011). Applying interpersonal theo-
& Day, R. (1986). Early manifestations and first‐contact incidence of
ries to the understanding of and therapy for auditory hallucinations: A
schizophrenia in different cultures. A preliminary report on the initial
review of the literature and directions for further research. Clinical
evaluation phase of the WHO Collaborative Study on determinants of
Psychology Review, 31(8), 1313–1323. https://doi.org/10.1016/j.
outcome of severe mental disorders. Psychological Medicine, 16(4),
cpr.2011.09.001
909–928.
Hayward, M., & Fuller, E. (2010). Relating therapy for people who hear
Schizophrenia Commission. (2012). The abandoned illness: A report
voices: Perspectives from clients, family members, referrers and from the schizophrenia commission. Retrieved from London:
therapists. Clinical Psychology & Psychotherapy, 17(5), 363–373.
Sommer, I. E., Slotema, C. W., Daskalakis, Z. J., Derks, E. M., Blom, J.
Hayward, M., Overton, J., Dorey, T., & Denney, J. (2009). Relating D., & van der Gaag, M. (2012). The treatment of hallucinations in
therapy for people who hear voices: A case series. Clinical schizophrenia spectrum disorders. Schizophrenia Bulletin, 38(4),
Psychology & Psychotherapy, 16(3), 216–227. 704–714.
Hsieh, H.‐F., & Shannon, S. E. (2005). Three approaches to qualitative
Thomas, N., Hayward, M., Peters, E., van der Gaag, M., Bentall, R. P.,
content analysis. Qualitative Health Research, 15(9), 1277–1288.
Jenner, J., … McCarthy‐Jones, S. (2014). Psychological therapies for
Jackson, L. J., Hayward, M., & Cooke, A. (2011). Developing positive auditory hallucinations (voices): Current status and key directions for
relationships with voices: A preliminary grounded theory. International future research. Schizophrenia Bulletin, 40(Suppl 4), S202–S212.
Journal of Social Psychiatry, 57(5), 487–495.
8 DELLAZIZZO L. ET AL.

Whitley, R., & Crawford, M. (2005). Qualitative research in psychiatry.


The Canadian Journal of Psychiatry, 50(2), 108–114. How to cite this article: Dellazizzo L, Percie du Sert O,
Yardley, L. (2000). Dilemmas in qualitative health research. Psychology Phraxayavong K, Potvin S, O'Connor K, Dumais A.
and Health, 15(2), 215–228. Exploration of the dialogue components in Avatar Therapy for
schizophre-nia patients with refractory auditory
Zhang, Y., & Wildemuth, B. M. (2016). Qualitative analysis of content.
Applications of Social Research Methods to Questions in Information hallucinations: A content analysis. Clin Psychol Psychother.
and Library Science, 318. 2018;1–8. https://doi.org/ 10.1002/cpp.2322

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