Brain's Puberty Switch -- Neuroendocrinologists Unlock Chemical Trigger to Puberty

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Brain's Puberty Switch Neuroendocrinologists Unlock Chemical Trigger to Puberty
May 1, 2005 — Researchers have discovered the precise chemical chain reaction that could be the much-sought-after puberty trigger: The KiSS-1 gene, which produces a protein in the hypothalamus, a part of the brain, which regulates metabolic activity. When the protein connects with a receptor on another gene called GPR54, puberty is believed to begin. This knowledge may guide the development of better drugs for treating hormone disorders related to puberty.
See also: Health & Medicine Hair Loss Children's Health Hormone Disorders Mind & Brain Gender Difference Spirituality Neuroscience Reference Delayed puberty Puberty Testosterone Lavender oil PITTSBURGH--They're politely called "the awkward years," but anybody who can remember going through puberty knows "awkward" is an understatement. Now medical researchers believe they're close to solving the puzzle of puberty. The awkwardness of growing up is not just a physical phenomenon. It's emotional ... And especially chemical.

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"Puberty, many people would expect, arises in the gonads and genitals organs. But in fact, puberty arises from the brain," says neuroendocrinologist Tony Plant.

Meditation Can Heal Did You Know That Meditating Just 15 min a Day Dr. Plant and a research team from Harvard University and Could Change Your Life www.SilvaLifeSystem.com the University of Pittsburgh discovered the precise chemical chain reaction that could be the much soughtAny Kind of AFM Tips after puberty trigger. AFM Tips For Any Application. Fast Delivery. Free "The brain sends an endocrine signal to the pituitary gland. Samples! NanoAndMore.com/Tips This makes protein hormones which reaches the ovaries and testes," Plant says. Aculas: Hair Loss Laser Rolls-Royce of Hair Loss Lasers Only 1 Reason It all begins with a kiss -- the KiSS 1 gene, which produces a protein in the hypothalamus. When the protein Effectiveness www.konftec.com connects with its receptor, the GPR54 gene, puberty begins. Dr. Plant says this is the first real handle we've had on the issue of the trigger. With wide variation, that trigger is pulled sometime between ages 10 and 16. But early or late puberty can pose developmental problems, like behavior problems and low self-esteem. Pediatricians have to treat these children with either precocious or delayed puberty. By knowing the exact chemical causes of puberty, medical researchers can now begin developing treatments that can harmonize the process. Right now, the only therapy for puberty disorders is frequent hormonal injections. With this genetic discovery, scientists hope oral medicines can be developed to either enhance or slow puberty where needed.

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A Gene's Fist 'Kiss' Sets Off That Affair Known As Puberty (February 2, 2005) — Puberty, that awkward phase when boys and girls are primed for their sexual reproductive years as men and women, appears to be triggered by the brain's own version of "It takes two to ... > read more The Hormone IGF-1: A Trigger of Puberty (July 26, 2010) — Puberty is triggered by pulsatile release of GnRH from specific nerve cells in the the brain. What signals tell these nerve cells to release GnRH in this manner has not been determined, although it ... > read more EPA1 In The Brain Regulates The Female

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http://www.sciencedaily.com/videos/2005/0512-brains_puberty_switch.htm[01.12.2010 13:15:12]

Brain's Puberty Switch -- Neuroendocrinologists Unlock Chemical Trigger to Puberty

Puberty is the developmental stage where a child starts to become sexually mature. It can occur between ages 8 and 11 for girls, and 9 to 12 for boys. As a child nears maturity, the brain -- specifically the parts known as the hypothalamus and the pituitary gland -releases chemicals called hormones. The hormones regulate the reproductive organs of both males and females. Girls produce estrogen and progesterone, while boys produce testosterone. Growth hormones also begin to work, causing the body to become larger, sometimes very quickly. The body also makes follicle stimulating hormones, leading to hair growth. All these extra hormones give rise to dramatic changes in the body.

Reproductive Cycle (July 15, 2007) — The onset of puberty and maintenance of the female reproductive cycle are events controlled by neurons in the hypothalamus that secrete gonadotropin-releasing hormone (GnRH). How signaling to these ... > read more Could a Pill Increase Learning Ability PostPuberty? (March 19, 2010) — New research shows that a novel brain receptor, alpha4-beta-delta, emerges at puberty in the hippocampus, part of the brain that controls learning and ... > read more Scientists Find Hormone Activity Explains Adolescent Mood Swings (March 12, 2007) — The "raging hormones" of puberty are known to produce mood swings and stress for most teenagers, making it difficult to cope with this period of life. Until now, the specific causes of pubertal ... > read more

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The first sign of puberty in girls is breast development. Then hair starts growing in the pubic area and armpits, followed by acne around age 13. Menstruation is typically the last stage to occur. In boys, the larynx lengthens and the voice "breaks" and then deepens. Also, there is growth in the testicles and penis, followed by hair growth in the pubic region and armpits. Acne and facial hair are the last developments. Both girls and boys may also experience strong emotions or mood changes. Editor's Note: This article is not intended to provide medical advice, diagnosis or treatment.

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Note: This story and accompanying video were originally produced for the American Institute of Physics series Discoveries and Breakthroughs in Science by Ivanhoe Broadcast News and are protected by copyright law. All rights reserved.

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