Generic/ Trade Name

Mechanism of Action Bactericidal

metronidazoleInhibits DNA synthesis of specific Medgyl (obligate) anaerobes Cell death

Dosage/ Frequen cy 500 mg 1 tab TID

Classificat ion Antibiotics , Antiprotoz oal, Amebicide , antibacter ial

Indication

Contraindication

Side effects

Nursing Responsibilities y Administer with food y Teach the patient to take the full course of drug therapy; alcohols are contraindicated (beverages or preparations containing alcohol, cough syrup) for 24-72 hr of drug use y Urine may be darker y Discontinue drug if hypersensitivity reaction occurs. y Report severe GI upset, dizziness, unusual fatigue or weakness, fever chills, and allergic reactions y Administer with food and milk y Reduce dosage if given with other antihypertensives , readjust dosage as BP responds y Give early in the day so that increased urination will not

y Acute infection with susceptible anaerobic bacteria

y

Contraindicat ed with hypersensitivi ty to metronidazol e

y

y

y

y

Dry mouth with strange metallic taste Dizziness, headache, diarrhea, Rash, itching, sore throat, fever, severe stomach pain, vomiting Urine may be darker

furosemide Furosemid e

Inhibits reabsorption of sodium and chloride proximal and distal tubules and ascending Loop of Henle Na, Cl,

20 mg 1 tab OD in am

Loop diuretic

y Edema associated with heart failure, cirrhosis, renal disease

y

y

contraindicat ed with allergy to furosemide, sulfonamides Severe renal failure

y

y y y y y

increased volume and frequency of urination dizziness feeling faint on arising drowsiness sensitivity to sunlight increased

Kexcretion in urine

y

thirst loss of potassium

disturb sleep y Do not expose to sunlight, which may discolor solution /tablet y Measure and record weight to monitor fluid changes y Arrange to monitor serum electrolytes, hydration, liver and renal function y Arrange for potassium-rich diet or supplemental potassium as needed y Avoid rapid position changes (when dizziness is experienced) y Instruct patient to Wear protective clothing and sunglasses when sensitivity to sunlight occurs y Report loss or gain of more than 3 lbs in 1 day, swelling in ankles or fingers, unusual bleeding or bruising, dizziness, numbness,

hypersensitivi ty. GIT and GUT infe ctions y Trimethoprim (TMP) Patients w/ marked liver parenchyma damage. hyperkalemia . megaloblastic bone marrow. diarrhea. product nutrition & water.fatigue. y Patients suffering from severe shock. severe disturbances of liver or kidney function & disturbance of amino acid metabolism y Septicemia. bacteremia y Patients w/ a tendency to elevated serum K or urea levels. thrombophle bitis. Too rapid infusion leading to renal loss & nausea cotrimoxazol e other name: trimethopri msulfametho xazole Cotrimoxaz ole Sulfathomexa zole (SMZ) Inhibits formation of dihydrofolic acid from PABA 500 mg tab BID Antibacter ial combinati ons y Resp tract. muscle weakness and cramps Aminogen Synthetic enzyme Breaks down protein (digestion) Easier absorption of protein Nitrogen retention Muscle and strength 500 cc IV q12 Parenteral y Supplement nutritional for protein. Nausea. headache y y y Assess patient¶s infection before therapy Obtain C/S before beginning drug therapy to identify if correct treatment has been initiated Assess for possible . blood dyscrasia. vomiting. abdominal pain. severe renal insufficiency.

nausea. swelling. rales. dizziness. itching. tachypnea. tachycardia. facial swelling fainting and seizures. dr y mouth or sinus congestion y y occurrence of drug induced adverse reaction Assess for signs and symptoms of anaphylaxis like wheezing. severe dizziness. if these are seen. coughing.Inhibits dihydrofolate reductase y Blocking synthesis of tetrahydrofoli c acid Blocks bacterial synthesis of folic acid y y AlbuterolIpratropiu m Combivent neb Ipratropium Inhibits vagally mediated reflex Antagonize acetylcholine Anticholinergi cs prevent increase in intracellular concentration of cyclic guanosine monophosph ate Q8 c/o RT Antiasthm atic y Management of reversible br onchospasm associated w/ obstructive airway diseases in patients who require more than a single bronchodilato r y Hypertrophic obstructive cardiomyopat hy or tachyarrhyth mia. History of hypersensitivi ty to soya lecithin or related food products (for MDI only) y Headache. trouble breathing) Provide / assist in Chest-Physio Therpy (CPT) after nebulization to loosen . discontinue drug Monitor renal function Administer drug with food Instruct patient to report and seek medical attention immediately when any allergic reactions occur (like rash.

y y Use cautiously with renal impairment. change in taste perception. heart failure. salt or volume depletion. Administer 1 hr before meals. mouth sores. history of angioedema y Cough. . GI upset. rash.Interaction with muscaranic receptor (bronchial smooth muscle) Bronchodilati on secretions Salbutamol Relaxes smooth muscle from trachea to terminal bronchioles Protects against bronchoconst rictor challenges Captopril Bronchodilati on Blocks ACE (converting Angiotensin I ± Angiotensin !!) Vasoconstrict s 25 mg / tab PRN for HPN ACE inhibitor Antihyper tensive y Treatment of hypertension alone or in combination with thiazidetype diuretics y Contraindicat ed with allergy to captopril. loss of appetite.

Na and fluid loss.Decreased BP. swelling of the face. irregular heartbeat. dizziness. and difficulty breathing . fever. chest pain. Mouth care for mouth sores Report mouth sores. chills. sore throat. Monitor patient for drop BP secondary to reduction in fluid volume (due to excessive perspiration. lightheadedness y y y Instruct patient to take drug without food. decreased aldosterone secretion. lips. dehy dration) excessive hypotension may occur. tongue. increased prostaglandin synthesis antihypertens ive action fast heart rate. increase in serum K. swelling of hands.. eyes.

fever. urticaria HEMAT: prolonged bleeding time LOCAL: injection site pain NEURO: paresthesia y y y Assess the patient on renal impairment.Ketorolac decreases the activity of the enzyme. weight gain. impaired hearing. headache RESP: asthma. dyspnea CV: edema. purpura. nausea GU: oliguria. rash. Assess skin color and lesions Instruct patient to report sore throat. recent GI bleeding. dyspepsia. abnormal taste. hypersensitivi ty to ketorolac CNS: drowsiness. dizziness. changes in vision. allergies. pallor. cyclooxygenase 30 mg IV q8 ANST () analgesic NSAID) results in decreased formation of prostaglandin precursors inhibits prostaglandin synthesis y For short term management of pain not exceeding five (5) days in all routes combined y Contraindicat ed with significant renal impairment. diarrhea. renal toxicity. GI pain. sweating. and bruising . swelling in ankles and fingers. euphoria. itching. concurrent use of NSAIDs. black tarry stools. aspirin allergy. active peptic ulcer disease. urinary frequency DERM: pruritis. vasodilation GI: GI Bleeding. dry mouth.

lightcolored stools. diabetes complicated with fever. major surgery. heart failure. severe trauma. coma. diarrhea. fever. type 1 diabetes y indigestion. do not crush or chew Instruct patient to report sore throat. unusual bleeding or bruising. sever infections. ketosis. abdominal discomfort y y y y y Assess patient on history to metformin. coma. ketosis. acidosis. sever infections. severe trauma. diabetes complicated by fever. major surgery. headache.metformin hydrochlori de Increases peripheral utilization of glucose Decreases hepatic glucose production Alters intestinal absorption of glucose 1 tab TID Home med Antidiabet ic y Adjunct to diet to lower blood glucose with type 2 DM y Metformin Contraindicat es with allergy to metformin. acidosis. dark urine. hypoglycemic or hyperglycemic . type 1 diabetes Assess skin color and lesions Instruct patient the following: do not discontinue this medication without consulting health care provider Instruct patient to Swallow ER tablets whole. nausea and vomiting.

vomiting. sweating/cla mmy skin. severe headache. hypothalamu s Altering perception of and emotional response to pain Relieves pain 10mg IV q6 x 2 doses Narcotic analgesic Opiate analgesic y Relief of moderate to severe pain y Can be used to as a supplement to balance anesthesia for preoperative and post operative anesthesia y Hypersensitiv ity to nalbuphine or any component of the formulation y Constipation . chest pain. vision changes Nalbuphine hydrochloride injection should be administered as a supplement to ge neral anesthesia . headache. lips. difficulty urinating. dizziness. swelling of the mouth. difficulty breathing. dizziness. nausea. feeling of a whirling motion. slow heartbeat. drowsiness.reactions Nalbuphine Binds with opiate receptors in CNS Ascending pain pathways in limbic system. tightness in the chest. hives. dry mouth. numbness of an arm or leg. thalamus. face. fainting. or tongue). y y y Report if severe reactions occur on patients such as severe allergic reactions (rash. seizures. or vomiting. midbrain.

difficulty breathing. y Anxiety. itching. during and after anesthesia y Hypersensitiv ity to fentanyl or adhesives. nausea.only by persons specifically trained in the use of intravenous anesthetics and management of respiratory effects of potent opioids Fentanyl Inhibits ascending pathways in CNS Increases pain threshold Alters pain receptors by binding to opiate receptors 50 mg IVP Analgesic y Short-term analgesia before. check liver. tightness in the chest. swelling of the mouth. dry mouth. confusion. note muscle rigidity. y Monitor VS after parenteral route. vomiting. difficulty walking. lips. indigestion. kidney function tests y Seek medical attention right away if any of these SEVERE side effects occur when using Fentanyl: Severe allergic reactions (rash. constipation. face. headache. take dug history after administering drug. hives. or tongue). . dizziness. drowsiness.

hypnotics and Sedative anticonvul sant y Insomnia y Sedation in critical care. muscle rigidity. y Monitor blod pressure. slowed breathing. and unexplained swelling y Assess patient¶s condition before therapy and regularly thereafter to monitor drug effectivess.5 mg Anxiolytic s. acute alcohol intoxication. Midazolam . airway integrity.0 mg + 1. arterial oxygen saturation (during procedures in patients premedicated with opioids). y Monitor for possible drug induced adverse reactions: headache. intrathecal and epidural admin. trouble breathing.hallucinations. hives. Emergency equipment should be nearby. itching. coma or patients in shock. severe respiratory depression y y y y y DOB Cardiac arrest Arrhythmia Hypotension Signs of allergic reaction including an unexplained rash. HR and rhythm. weakness. Acute pulmonary insufficiency or marked neuromuscul ar respiratory weakness including unstable myasthenia gravis. seizures. RR. Increasing the inhibitory neurotransmi tter activity of GABA Depresses the limbic system and reticular formation 2. slow or irregular heartbeat. minor surgical procedures y Induction of anesthesia y Pre-med in surgical procedure y acute narrow-angle glaucoma.

nausea. wheezing. flushing (redness). hypotension. anaesthetic and cardiorespiratory effects when used with other CNS depressants Propofol . palpitations y lightheadedne ss or fainting spells y numbness or tingling in the hands or feet seizure (convulsion) y skin rash. bradypnea positive modulation of the inhibitory function of the neurotransmi tter gamaaminobutyric acid (GABA) through GABAA receptor decreased pain sensation 2 ml IVP intermit tent Anestheti c ± Local and General y Induction and maintenance of general anesthesia Electroconvulsive therapy y difficulty breathing. PR cardiac arrest. or itching y swelling or extreme pain at the injection site y uncontrollabl e muscle spasm y Reduce dose if given with nitrous oxide or halogenated anaesthetics. involuntary movements.oversadation. swelling of the throat y fast heartbeat. amnesia. Increased sedative. vomiting. hiccups.

mental or mood changes. Eye injury. Contraindicated in patient hypersensitivity to drug CNS: dizziness CV: flushing. don¶t delay other measures. Dependence and tolerance may develop. Vit. nightmares. K 1 amp IV q 8 Haemosta tic Drug y Hypoprothrom binemia caused by effects of oral y Hypoprothrom binemia caused by Vit. vomiting y Minimise verbal and tactile stimulation during recovery period. y May impair ability to drive or operate machinery. Preanaesthetic elevated CSF pressure. glutamic acid at the NMDA receptors 50 mg Anestheti c ± Local and General y Induction of anesthesia y hypertension. transient hypotension after IV administration. such as administration . confusion. rapid and weak pulse y Check brand name levels for administration route restriction. raised ocular and intracranial pressure. Chronic alcoholic and alcoholintoxicated patients.ketamine Depresses CNS Blocking the effects of excitatory neurotransmi tter. increased or decreased blood pressure or heart rate. K malabsorption. y Monitor cardiac function in patients with hypertension or cardiac decompensation. nausea. Psychotic disorders y Blurred vision. y If severe bleeding occurs. history of cerebrovascula r accident. drowsiness.

condition may progress to shock. Skin: diaphoresis. y tell patient not to change drug dosage without prescribers consent and to report abnormal Eugeclav 1 Tablet BID 3xday Antidiabet ic Adjunct to diet to lower glucose level in patients with type 2(non-insulindependent) diabetes Contraindicated in patients hypersensitivity to drug and in those with diabetic ketoacidosis with or without coma EENT: changes in accommodation or blurred vision GI: nausea. tachycardia. losing weight. or excessive Vit. weakness. and avoiding infection. and hypotension. epigastric fullness. K doesn¶t reverse the anticoagulant effects of heparin.drug therapy. and hematoma in injection site of fresh frozen plasma or whole blood. erythema IV: pain. y instruct patient about nature of disease and importance of following therapeutic regimen. following personal hygiene programs. adhering to specific diet. getting exercise. y Vit. A dosage. heartburn HEMATOLOGIC: hemolytic anemia HEPATIC: cholestatic jaundice METABOLIC: hypoglycemia . y Watch for flushing. swelling.

hypotension. anorexia GU: dysuria. diphenhydr amine 1 amp. vomiting. y Warn patient not to take this drug with any other products that contain diphenhydramine because of increase reaction. headache. pruritus.Skin: rash. allergy symptoms. other allergic reactions blood or urine glucose test result. drowsiness. . tachycardia SKIN: urticaria. motion sickness Contraindicated in patients hypersensitivity to this drug CNS: fatigue. sleepiness. tremor. restlessness. seizures. IV now Antihista mine Rhinitis. y Tell patient to notify prescriber if tolerance develops because a different antihistamine may need to be prescribed. GI: nausea. constipation. confusion. urine retention. urinary frequency HEMATOLOGIC: hemolytic anemia CV: palpitations. nervousness. dizziness.

‡Obtain specimens for culture and sensitivity prior to initiating therapy. urticaria to anaphylactoid reactions ‡Local: Pain following injection. ‡Monitor renal and liver function tests. history of asthma or other allergies. cardiac arrest (with rapid IV infusion) ‡Hypersensitivit y: Rashes. ‡Do not use for minor bacterial or viral infections. and blood counts with prolonged therapy. rash Clindamyci n Stops or slows the growth or proliferation of cells 300 mg IV q 4hr Lincosami de antibiotic disrupting the processes that lead directly to the generation of new proteins Adjunct to surgical treatment of chronic bone and joint infections due to susceptible organisms Allergy to clindamycin. WBC) at beginning and throughout therapy ‡Assess for allergy to clindamycin. appearance of wound. hepatic or renal dysfunction ‡CV: Hypotension. causing cell death .photosensitivity. indurations and sterile abscess after thrombophlebiti s after IV use ‡Assess for infection (vital signs.

nasal trauma. pharyngitis. dry mouth ‡Local: Nasal irritation ‡Respiratory: Epistaxis. rebound congestion. bruising. recent nasal surgery. ‡CNS: Headache. ‡Advice patient to report sore mouth. Maximizes beneficial effects on tissues While decreasing the likelihood of adverse effects from systemic absorption. do not stop without consulting your health care provider.Budesonid e Antiinflammatory effect Nebuliza tion q 8hr. Cushing's syndrome with overdosage and systemic absorption ‡GI: Nausea. exposure to chickenpox or measles. . septal ulcers. lactation ‡Do not use more often than prescribed. dyspepsia. alopecia ‡Endocrine: HPA suppression. fatigue ‡Dermatologic: Rash. cough ‡Other: Chest pain. dizziness. Corticoste roid Local administratio n into nasal passages Used for management of bronchial asthma and symptomatic management of seasonal or perennial allergic rhinitis ‡Hypersensitivity to drug or for relief of acute asthma or bronchospasm. eye infections occur. worsening of symptoms. severe sneezing. ‡It may take several days to achieve good effects. edema. acne. pruritus. back pain ‡Assess for untreated local nasal infections. sore throat.

fever or infection. diarrhea. ‡GI: diarrhea.Diamicron Gliclazide is a sulfonylurea 1 tab. patients with poor diet. flatulence ‡Hypersensitivit y: urticaria. sulbactam or cephalosporins. lactation. stomach upsets. hepatitis ‡Follow as closely possible the diet prescribed by the doctor ‡Regularly carry out the laboratory tests as prescribed or recommended by the doctor ‡Inform the doctor in the ff. ‡Advice patient to report if severe diarrhea with blood. trauma. abdominal pain. itching. ketoacidosis. ‡The once-daily administration of Diamicron MR must always be followed by a meal. pus or mucus. ‡Do not take a double dose to compensate for the single dose that was not taken. Normalizes fasting and postprandial blood sugar. vomiting. in association with dietary measures and with exercise. difficulty in eating. ‡Assess for hypersensitivity to any cephalosporin. Gliclazide restores glycaemic control throughout 24 hrs. diabetic precoma. pruritus. severe renal or hepatic impairment. BID Oral anti diabetic agent Stimulates insulin secretion by the pancreas Resulting in a physiological release of insulin For non-insulin dependent diabetes (type 2). pallor. nausea. skin rash ‡GI: Nausea. Coadministration with miconazole ‡Hypoglycemic: sweating. ‡Dermatologic: urticaria. pregnancy. malaise. intense hunger. ‡Contraindicated with Type 1 diabetes. constipation. unusual . when these measures alone are not sufficient. hepatic dysfunction and renal impairment. cases: Surgery. anorexia. Bactericidal Sulferazon e Inhibits bacterial cell wall synthesis Cell death 300 mg IV q 4hr Third generatio n of Cephalosp orins Skin & soft tissue infections ‡Hypersensitivity to penicillins. difficulty of breathing.

‡Monitor patient closely. irritation or itching and unusual bleeding occurs Humulin Increases glucose transport across muscle ad fat cell membranes 20/30 20 units pre BF 15 pre dinner Antidiabet ics Treatment of diabetes mellitus for the control of hyperglycemia. Local and generalized allergic reactions ‡Dosage is always prescribed in USP units. ‡Advice patient to wear or carry medical identification at all times. ‡CV: hypotension. anaphylactoid reaction / shock ‡CNS: Headache. Hypoglycemia Adverse Reaction: Lipodystrophy.pregnancy and lactation. insulin resistance. ‡Instruct patient to avoid vigorous exercise. Reduce glucose level . ‡Teach patient to avoid alcohol use. ‡Make sure that patient knows that insulin relief pain but does not cure disease.

dyspepsia. y for better analgesic effect. Serious hypersensitivity reaction can occur. vomiting. confusion. Drug can produce defence similar to that of codeine or dextropropoxyphe ne and thus has potential for abuse. CNS stimulation. diarrhea. and in those w/ intoxication from alcohol. y in case of an overdose. vertigo. sleep disorder. Thought to bind opioate receptor and inhibit reuptake of nor epinephrine and serotonin 50 mg lV q6 Opioid analgesic Moderate to moderately severe pain. constipation. GI: nausea. centrally acting analgesics. anorexia. seizure. asthenia. hypnotics. Drug may reduce seizure threshold. nervousness. opioids or psychotropic drugs. usually after the first dose. naloxone may also increase risk of seizures. in breast feeding women. somnolence. y monitor cu and respiratory status with hold dose and notify prescriber if respirations decrease or rate is below 12 breaths per minute. malaise CV: vasodilation EENT: visual disturbances. Use cautiously in patients at risk for seizures or respiratory depression. urinary frequency. Contraindicated in patients¶ hyper sensitive to drugs other opiods. in patients w/ increase intracranial pressure or head injury. euphoria. anxiety.Tramadol hydrochlori de Ultram Unknown a centrally acting synthetic analgesic compound not chemically related to opoids. flatulence GU: urine retention. proteinuria Musculoskeletal: hypertonia Respiratory: respiratory depression y reassess patient¶s level of pain at least 30 minute after administration. y monitor patient for drug dependence. dry mouth. . menopausal symptoms. give drug before on set of intense pain. coordination dis-turbace. Patients w/ history of anaphylactic reaction to codeine and other opioids maybe at increase risk. headaches. acute abdominal NS: dizziness. abdominal pain. y monitor patient at risk for seizures.

Do not confuse drug w/ cephalosporin that sound alike. vomiting. or penicillin. CNS: fever. y monitor patients for super infection. hypersensitivity reactions anaphy laxis. 1 tab OD 3th generatio n cephalosp orin Mild to moderate UTI caused by Escherichia coli. w/ renal function. diarrhea. cephalosporin. y look alike sound alike. . pruritus uticaria OTHER: pain inflammation. ural candidiasis SKIN: rash. Cefepime Hydrochlori de Maxipime Bactericidal Inhibits bacterial cell wall synthesis Cell death 500mg.condition or renal or hepatic impairment or in patients w/ physical dependence on opioids. don¶t confuse tramadol w/ trazodone or trandolapril. including concurrent bacteremia w/ these micro organism. headaches CV: phlebitis GI: colitis. klebsiella pneumonia. y use cautiously in patients¶ hypersensitivit y to penicillin because of possibility of cross sensitivity w/ other betalactamantibioti cs y use cautiously in breast feeding women and in patients w/ history of colitis or renal insufficiency. rash. Skin: pruritus. y adjust dosage in pt. proteus minabbilis. y obtain culture and sensitivity test. beta-lactam antibiotics. y withdrawal symptoms may occur if drug is stopped abruptly reduce dosage gradually look alike sound. diaphoresis. nausea. y before giving drug ask patients if he/she is allergic to penicillin or cephalosporin. y patient w/ hypersensitive to drugs.

nausea. urenia. piperacillin tazobactamsusceptible beta-lactamase producing strains of microorganism in appendicitis and peritonitis caused by escherichia coli.Piperacillin tazabactta m Zosyn Bactericidal Inhibits bacterial cell wall synthesis Cell death 2. bacteroides fragills. CV: hypertension. coli. y drug is typically used as another antibiotic. because of possible cross sensitivity CNS: fever . agitation. hypokalemia. vomiting. chest pain. . Ovactus. dyspepsia. insomnia. stool changes. b vulgates. abdominal pain. B thetaiotaomicro n. GU: interstitial nephritis. tachycardia. seizures. such as gentamicin y if large doses are given or if therapy is prolonged. anxiety. skin and skin structure infections caused by straphylococcus aureus. moderately to Contraindicated in patients hypersensitive to drug on other pencillins. headaches. especially in elderly. and allergies to other drug. pseudomen branous colitis. edema EENt: rhinitis GI: diarrhea. postpartium endometritis of pelvic inflammation disease caused by e. y Use cautiously in patients with bleeding tendencies. dizziness. constipation. thrombocy y Before giving drug ask patient about allergic reaction to penicillin y obtain specimen for culture and sensitivity test before bacteriostatic antibiotic y give tecarcillin at least II hour before bacteriostatic antibiotic y monitor potassium and sodium levels y check cbc and platelet counts frequently. anemia eosinophilia. bacterial or fungal super infection may occur.25g lV q8 (-) ANST Anti infectives Moderate to severe infections from piperacillin resistant. especially cephalosponins . B. candidiasis. HEMATOLOGIC: leukopenia.

dizziness. ‡Administer oral drug 1 hr before or 2 hr after meals with a glass of water. pruritus OTHERS: pain. 1. levofloxaci n Loxeva Bactericidal: Interferes with DNA by inhibiting DNA synase replication in susceptible gramnegative and gram-positive bacteria. at IV site.Arrange for culture and sensitivity tests before beginning therapy. hypersensitivity reaction. Respiratory: dsypnea SKIN: rash. constipation. AST. seizures. inflammation. pregnancy. acute maxillary sinusitis caused by susceptible bacteria ‡Treatment of acute exacerbation of chronic bronchitis caused by susceptiblebacte ria ‡Treatment of Contraindications and cautions ‡Contraindicated with allergy to fluoroquinolones. CNS:Headache. anaphylaxis. diarrhea . . blurred vision ‡GI:Nausea. dry mouth. flatulence ‡Hematologic: E levated BUN. separate oral drug from other cation administration. preventing cell reproduction 500mg tab od antibiotic Treatment of adults with communityacquired pneumonia. vo miting. abdominal pain (occur less with this drug than with oflaxacin). ALT. lactation. phlebitis. insom nia. including antacids. ‡Continue therapy as indicated for condition being treated. fatigue.severe community acquired pneumonia caused by haemophilus influenzae topenia. neutropena. ‡Use cautiously with renal dysfunction. somnolence. debilitated or immunusuppresse d patients.

‡Discontinue drug at any sign of hypersensitivity (rash. photosensi tivity. neutropenia. Staphylococcuss pec ies ‡Treatment of nosocomial pneumonia due to methicillinsensitiveStaphyl ococcus aureus. or rupture. if no improvement is seen or a relapse occurs. rash. and alkaline phosphatase. muscle and joint tenderness by at least 2 hr. ‡Ensure that patient is well hydrated during course of therapy. ‡Monitor clinical response. Pseudomonasstr serum creatinine. inflammation. anemia ‡Other: Fever. . repeat culture and sensitivity test. Enterococcus faecalis.complicated and uncomplicated skin and skin structure infections caused by susceptible bacteria ‡Treatment of complicated and uncomplicated UTIs and acute pyelonephritis caused by susceptible bacteria ‡Treatment of chronic bacterial prostatitis due to Escherichia coli. photophobia) or and complaint of tendon pain.

Streptococcus pneumoniae . Klebsiella species. Haemo philus influenzae. Escherichia coli.ains. Serratiasp ec ies.