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Chlorpromazine ( Thorazine )

Chlorpromazine ( Thorazine ) is an antipsychotic drug of low-potency used to treat schizophrenia.


Chlorpromazine ( Thorazine ) is used in the treatment of disorganized and psychotic thinking. Also
used to help treat false perceptions (e.g. hallucinations or delusions.) Chlorpromazine
( Thorazine ) is also sometimes to treat psychotic children. It may be used to treat sever hiccups
or protracted nausea.

Chlorpromazine ( Thorazine ) is also prescribed for the short-term treatment of severe behavioral
disorders in children, including explosive hyperactivity and combativeness; and for the
hyperenergetic phase of manic-depressive illness ( severely exaggerated moods ).

Chlorpromazine ( Thorazine ) is also used to control nausea and vomiting, and to relieve
restlessness and apprehension before surgery. It is used as an aid in the treatment of tetanus, and
is prescribed for uncontrollable hiccups and acute intermittent porphyria ( attacks of severe
abdominal pain sometimes accompanied by psychiatric disturbances, cramps in the arms and legs,
and muscle weakness ).

Strengths:

Tables:
25 mg, 50 mg, 100 mg, 200mg.

Dosages: Actual dosage must be determined by a physician.

Adults:

Schizophrenia and Mania


Start : 25 mg to 75 mg daily.
Increases : 20 mg to 50 mg semiweekly.

Nausea and Vomiting


10 to 25 milligrams, taken every 4 or 6 hours, as needed.
One 100-milligram suppository can be used every 6 to 8 hours.

Uncontrollable Hiccups
Dosages may range from 75 to 200 milligrams daily, divided into 3 or 4 equal doses.

Acute Intermittent Porphyria


Dosages may range from 75 to 200 milligrams daily, divided into 3 or 4 equal doses.

Normal dosage:

If under 18 years of age, DO NOT USE.


18 to 60 years of age, 75 to 200 milligrams daily.
Over 60 years of age, lower dosage.

Problems with:

Liver Function:
Kidney Function:

Take With:

Full Benefits In: Up to 3 months..

Missed Dose(s): If within one hour take, if over an hour skip and then continue on your normal
schedule. Never Take a Double Dose.
If Stop Taking: Do not stop without consulting your physician .

Overdose symptoms include: Parkinsonism, acute dystonias, somnolence, seizures, dry mouth,
blurred vision, urinary retention, tachycardia, cardiac arrhythmias, hypotension, hypothermia or,
hyperthermia. Can be fatal.

Warnings

Antacids containing aluminum or magnesium should not be taken one hour before taking this drug
and never right after.

Only take this drug and Heterocyclic antidepressants with careful monitoring. Also check with
your physician if you are taking central nervous system depressants like antihistamines, hay fever
medicines, sedatives, narcotics, anesthetics, barbiturates or muscle relaxants. Also check with
your physician if you are taking a vasodilator (drug that dilate blood vessels.)

The habit-forming potential is none, but long term use may lead to Tardive Dyskinesia.

Do not take this drug if you are pregnant ( Only take if the mother's or baby's life is endangered. )

Do not take this drug if planning to become pregnant. Do not take if you are breast-feeding.

Do not give this drug to anyone under six months old. Only use drug in small doses at first if over
sixty and with close monitoring. Also if over sixty be careful when standing up because blood
pressure may be lowered enough to impair balance.

Do not use if: You had negative reactions to this drug or any other phenothiazine in the past.

Inform your Doctor if: You had negative reactions to this drug or any other phenothiazine in the
past. If you have epilepsy or asthma. If you have cardiovascular or liver disease. If you are taking
any other prescription or nonprescription drug. If you plan to be under anesthesia or having any
surgery in the next few months, also if you will be undergoing any medical tests. If you are on a
special diet ( low-salt / low-sugar or any other.)

Thorazine may cause tardive dyskinesia--a condition marked by involuntary muscle spasms and
twitches in the face and body. This condition may be permanent, and appears to be most common
among the elderly, especially women. Ask your doctor for information about this possible risk.

Chlorpromazine ( Symptoms or Effects )

Common: Lethargy / sleepiness, low blood pressure, dry mouth, blurred vision, constipation,
weight gain, difficulty urinating or stiffness. Abnormal secretion of milk, abnormalities in
movement and posture, agitation, anemia, asthma, blood disorders, breast development in males,
chewing movements, constipation, difficulty breathing, difficulty swallowing, dizziness, drooling,
drowsiness, dry mouth, ejaculation problems, eye problems causing fixed gaze, fainting, fever, flu-
like symptoms, fluid accumulation and swelling, headache, heart attack, high or low blood sugar,
hives, impotence, inability to urinate, inability to move or talk, increase of appetite, infections,
insomnia, intestinal blockage, involuntary movements of arms and legs, tongue, face, mouth, or
jaw, irregular blood pressure, pulse, and heartbeat, irregular or no menstrual periods, jitteriness,
light-headedness (on standing up), lockjaw, mask-like face, muscle stiffness and rigidity, narrow
or dilated pupils, nasal congestion, nausea, pain and stiffness in the neck, persistent, painful
erections, pill-rolling motion, protruding tongue, puckering of the mouth, puffing of the cheeks,
rapid heartbeat, red or purple spots on the skin, rigid arms, feet, head, and muscles (including the
back), seizures, sensitivity to light, severe allergic reactions, shuffling walk, skin inflammation and
peeling, sore throat, spasms in jaw, face, tongue, neck, mouth, and feet, sweating, swelling of
breasts in women, swelling of the throat, tremors, twitching in the body, neck, shoulders and face,
twisted neck, visual problems, weight gain, yellowed skin and whites of eyes.
Rare: Dizziness, racing heartbeat / palpitations, weakness, sexual problems, restlessness, skin
rash, seizures, low white blood cell count, tremors or involuntary facial / tongue movements.

See physician always: Low blood pressure, dizziness, racing heartbeat / palpitations, weakness,
sexual problems, restlessness, skin rash, stiffness, seizures, low white blood cell count, tremors,
reduced urinary output, difficulty urinating or involuntary facial / tongue movements.

See physician if severe: Lethargy / sleepiness, dry mouth, blurred vision, constipation or weight
gain.

See physician NOW: Involuntary facial / tongue movements or skin rash.

Stop taking and see physician NOW: Seizures.

Chlorpromazine ( Thorazine ) Interactions

• Anesthetics.
• Antacids such as Gelusil.
• Antiseizure drugs such as Dilantin.
• Antispasmodic drugs such as Cogentin.
• Atropine ( Donnata l).
• Barbiturates such as phenobarbital.
• Blood-thinning drugs such as Coumadin.
• Captopril ( Capoten ).
• Cimetidine ( Tagamet ).
• Diuretics such as Dyazide.
• Epinephrine ( EpiPen ).
• Guanethidine.
• Lithium (Lithobid, Eskalith).
• MAO inhibitors ( antidepressants such as Nardil and Parnate ).
• Narcotics such as Percocet.
• Propranolol ( Inderal ).
• Trifluoperazine ( Stelazine )
• Trifluoperazine ( Stelazine ) is an anti psychotic drug of high-potency. Used in the
treatment of disorganized and psychotic thinking. Trifluoperazine ( Stelazine ) is also used
to help treat false perceptions ( e.g. hallucinations or delusions ).
• THIS DRUG MAY CAUSE NEUROLEPTIC MALIGNANT SYNDROME.
• Warnings
• Antacids containing aluminum or magnesium should not be taken one hour before taking
this drug and never right after.
• Only take this drug and Heterocyclic antidepressants with careful monitoring. Also
check with your physician if you are taking central nervous system depressants like
antihistamines, hay fever medicines, sedatives, narcotics, anesthetics, barbiturates or
muscle relaxants. Also check with your physician if you are taking a vasodilator ( drug that
dilate blood vessels ).
• The habit-forming potential is none, but long term use may lead to Tardive Dyskinesia.
• Do not take this drug if you are pregnant ( Only take if the mother's or baby's life is
endangered ).
• Do not take this drug if planning to become pregnant. Do not take if you are breast-
feeding.
• Children may take this drug, but most be under the care of a pediatrician or children's
psychiatrist. Only use drug in small doses at first if over sixty and with close monitoring of
side effects. Also if over sixty be careful when standing up because blood pressure may be
lowered enough to impair balance.
• If you smoke blood levels of this drug need to be taken. Smoking drops this drugs level in
the blood.
• Do not use if: You had negative reactions to this drug or any other phenothiazine in the
past.
• Inform your Doctor if: You had negative reactions to this drug or any other phenothiazine
in the past. If you have epilepsy or asthma. If you are taking any other prescription or
nonprescription drug. If you plan to be under anesthesia or having any surgery in the next
few months, also if you will be undergoing any medical tests. If you are on a special diet
( low-salt / low-sugar or any other ).
• Trifluoperazine ( Symptoms or Effects )
• Common: Lethargy / sleepiness, low blood pressure, dry mouth, blurred vision,
constipation, weight gain, difficulty urinating or stiffness.
• Rare: Dizziness, racing heartbeat / palpitations, weakness, sexual problems, restlessness,
skin rash, seizures, low white blood cell count, tremors, involuntary facial / tongue
movements or reduced urinary output.
• See physician always: Low blood pressure, dizziness, racing heartbeat / palpitations,
weakness, sexual problems, restlessness, skin rash, stiffness, seizures, low white blood
cell count, tremors, reduced urinary output, difficulty urinating or involuntary facial /
tongue movements.
• See physician if severe: Lethargy / sleepiness, dry mouth, blurred vision, constipation or
weight gain.
• See physician NOW: Low white blood cell count or reduced urinary output.
• Stop taking and see physician NOW: Seizures or skin rash.

Haloperidol ( Haldol, Haldol Decanoate, Halperon )


( In Canada ( Apo-Haloperidol, Haldol LA, Novo-Peridol, Peridol, PMS-Haloperidol )

Haloperidol ( Haldol, Haldol Decanoate,Halperon ) is an antipsychotic drug of high-potency, strong


tranquilizer. Haloperidol ( Haldol,Haldol Decanoate, Halperon ) is used in the treatment of acute
psychosis,acute schizophrenia,manic phases, to control aggression,to controlagitation,disorganized
and psychotic thinking. It may also be used to help treat false perceptions. ( e.g. hallucinations or
delusions ) or in the treatment of Gilles de la Tourette syndrome. To treat psychosis associated
with dementia, depressions, or mania. This drug however is more likely to cause movement side
effects like Tardive Dyskinesia,then most other antipsychotic drugs. Generally accepted uses not
FDA approved include, adjuvant for in chronic pain, control vomiting from chemotherapy, ease
refractory sneezing, control refractory hiccups, lessen delirium from LSD flashbacks, lessen
delirium from phencyclidine intoxication, or may be helpful in autistic persons.

CLASS: Butyrophenone.
Generic name: Haloperidol, Haloperidol Lactate, and Haloperidol Decanoate.
Type: Antipsychotic.

Strengths:

Tables:
0.5 mg, 1 mg, 2 mg, 5 mg, 10 mg, 20 mg.

Concentrate:
2 mg per ml

Injection:
5 mg, 50 mg per ml, 100 mg per ml.

Decanoate is long-acting.

Dosages:Actual dosage must be determined by a physician.

Oral:

Start: 0.5 mg to 2 mg, 2 or 3 times daily.


Increases: 0.5 mg in 3 or 4 day intervals, as needed.
Maintenance: Low as possible in 24 hours.
Maximum: 100 mg in 24 hours.

Normal dosage:

If under 18 years of age, Only if under the care of a child psychiatrist!


18 to 60 years of age, 0.5 mg to 30 mg daily.
Over 60 years of age, Lower dosage increased cautiously.

Problems with:

Liver Function: Lower dosage, as needed.


Kidney Function: High dosage with caution and only as needed.

Test:

Before taking: None.


While taking: Haloperidol levels regularly.

Take With: Empty stomach and a full glass of water.

Full Benefits In: In several weeks.

Missed Dose(s): If within one hour take, if over an hour skip and then continue on your normal
schedule.
Never Take a Double Dose

If Stop Taking: Do not stop without consulting your physician and never abruptly. Withdraws
may include muscle spasms.

Overdose symptoms include: Coma, Convulsions, profound drowsiness, tremor, or weakness.

Warnings

Antacids containing aluminum or magnesium should not be taken one hour before taking this drug
and never right after.

Only take this drug and Heterocyclic antidepressants with careful monitoring. Check with your
physician if you are taking central nervous system depressants like antihistamines, hay fever
medicines,sedatives, narcotics, anesthetics,barbiturates, or muscle relaxants. Check with your
physician if you are taking a vasodilator ( drug that dilate blood vessels ).

Do not smoke and take this drug.

The habit-forming potential is none, but long term use may lead to tardive dyskinesia.

Long term use may lead to neuroleptic malignant syndrome.( NMS )

Do not take this drug if you are pregnant ( Only take if the mother's or baby's life is endangered. )

Do not take this drug if planning to become pregnant.

Do not take if you are breast-feeding.

Children may take this drug but only under the watchful eye of a physician.
Only use drug in small doses at first if over sixty and with close monitoring. If over sixty be careful
when standing up because blood pressure may be lowered enough to impair balance.

Do not use if:

• you had negative reactions to this drug in the pass.


• if you have Parkinson's disease.
• if you are taking lithium.

Inform your Doctor if:

• you had negative reactions to this drug or any other drug in the past.
• if you have epilepsy,asthma,or cardiovascular disease.
• if you have chest pains, history of breast cancer, or glaucoma.
• if you have liver disease.
• if you are taking any other prescription or nonprescription drug.
• if you will have anesthesia or any surgery in the next few months.
• if you will be undergoing any medical tests.
• if you are on a special diet ( low-salt / low-sugar or any other ).

Haloperidol ( Symptoms or Effects )

Common: Akathisia, akinesia,lethargy / sleepiness, low blood pressure, dry mouth, blurred vision,
constipation, weight gain, difficulty urinating, or stiffness ( Acute dystonia ).

Rare: Dizziness,racing heartbeat / palpitations, weakness, sexual problems, restlessness, skin


rash, seizures, low white blood cell count, tremors, or involuntary facial / tongue movements.

See physician always: Akathisia, akinesia, dizziness, low blood pressure, racing heartbeat /
palpitations, weakness, sexual problems, restlessness, skin rash, stiffness ( Acute dystonia ),
seizures, low white blood cell count, tremors, reduced urinary output, difficulty urinating, or
involuntary facial / tongue movements.

See physician if severe: Lethargy / sleepiness,dry mouth, blurred vision, constipation, or weight
gain.

See physician NOW: Reduced urinary output.

Stop taking and see physician NOW: Seizures.