PATHOPHYSIOLOGY OF RUPTURED APPENDICITIS

Non-modifiable -20 yrs old Gender: male (male- female =2:1) Modifiable y Diet: People whose diet is low in fiber and rich in refined carbohydrates. y Infections: Gastrointestinal infections such as Amebiasis, Bacterial Gastroenteritis, Mumps

Episodes of constipation

Obstruction of the appendix by (fecalith (hardened stool), lymph node, tumor, foreign objects)

Increase in pressure inside the appendix lumen that result to distention of appendix

Impaired venous return causing hyperemia (improper O2, and nutrient supply) Normal bacteria found in appendix begin to invade (infect) the lining of the wall

causing Guarding. fecal materials exits to peritoneal cavity causing formation of abscesses (periappendiceal abscess). and weight loss Release of prostaglandin/ bradykinin Sepsis (the condition or syndrome caused by the presence of microorganisms or their toxins in the tissue or the bloodstream ) -Septicemia .It can be treated through antibiotic and fluid replacement Pain in surgical site Activity intolerance Recovery .Infection can spread throughout the abdomen (peritoneal cavity Starts of inflammatory process Bacterial invasion of Peritoneal Cavity causing inflammation of the membrane that lines the abdomen peritoneum (Peritonitis) S/S: swelling of the abdomen. and increase swelling of appendix.causes swelling of tissue resulting to inflammation of appendix Inflammatory Response ± body response to the bacterial invasion in the wall of appendix. The appendix ruptures due Pain. severe pain. Vomiting & loss of appetite Tissue Trauma Disruption of cell membrane Perforation (formation of a hole in an organ). Increased Immune complex S/S: abdominal pain.located @ RLQ. Vomiting and loss of appetite Appendectomy inflammation and infection spread through the wall of the appendix causing death of tissue. fever.

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