Name of the drug Drug Action Indication Contraindication Side effects Interactions Nursing consideration

Generic Name: is not definitely indicated for the Patients who are * allergic reactions Drugs which may *Take Dilantin exactly as
Phenytoin known, but control of tonic- allergic to like skin rash, itchingincrease prescribed by your doctor.
extensive research clonic (grand mal) phenytoin or other or hives, swelling of phenytoin serum
Brand name: strongly suggests and psychomotor hydantoins the face, lips, or levels include: * If you are taking
Dilantin that its main (temporal lobe) tongue acute alcohol Dilantin to treat seizures,
mechanism is to seizures. *breathing problems intake, keep taking the
block frequency-, amiodarone, medication even if you
*changes in vision
use- and voltage- chloramphenicol, feel fine. You may have an
*chest pain
dependent neuronal chlordiazepoxide, increase in seizures if you
*confusion
sodium channels, cimetidine, stop taking Dilantin.
*dark yellow urine
and therefore limit diazepam, Follow your doctor's
*fast or irregular
repetitive firing of dicumarol, instructions.
heartbeat
action potentials. disulfiram, *Do not change your dose
*loss of seizure
estrogens, of Dilantin without your
At usual levels, control
*poor control of body ethosuximide doctor's advice.
there is little or no
*Drugs which
change in normal movements or
may decrease
patterns of firing. At *difficulty walking
phenytoin levels
high or toxic levels, redness, blistering,
however, phenytoin peeling or loosening include:
can impair the of the skin, including carbamazepine,
chronic alcohol
function of healthy inside the mouth
neurons. unusual bleeding or abuse, reserpine,
bruising, pinpoint red and sucralfate
spots on skin
vomiting
worsening of mood,
thoughts or actions of
suicide or dying
yellowing of the eyes
or skin
Generic Name: . The activity of used to treat adults Lantus is Hypoglycemia, Effects enhanced *Do not take Lantus® if
insulin glargine LANTUS® results with type 2 diabetes contraindicated in temporary visual by oral you are allergic to insulin
in a relatively and adults and patients with impairment, antidiabetics, or any of the inactive
Brand name: constant children (6 years hypersensitivity to lipodystrophy, inj site ACE inhibitors, ingredients in Lantus
Lantus concentration/time and older) with type Lantus or one of its & allergic reactions disopyramide, *You must test your blood
profile over 24 1 diabetes for the excipients including redness, fibrates, sugar levels while using
hours with no control of high pain, itch, hives, fluoxetine, insulin
pronounced peak. blood sugar. swelling or MAOIs, *Do not make any
This profile is what inflammation. Rarely, pentoxifylline, changes to your dose or
allows LANTUS® sodium retention & propoxyphene, type of insulin without
to be dosed once a edema. salicylates, talking to your healthcare
day at the same sulfonamide provider. Any change of
time each day as a antibiotics. insulin should be made
patient's basal Effects reduced cautiously and only under
insulin. The time by corticosteroids, medical supervision.
course of action of danazol, *Do NOT dilute or mix
insulins, including diazoxide, Lantus with any other
LANTUS®, may diuretics, insulin or solution
vary between glucagon, INH,
individuals and estrogens &
within the same progestogens,
individual. phenothiazine
derivatives,
Long-acting
somatropin,
LANTUS®
sympathomimetic
provides a
s or thyroid
continuous level of
hormones. β-
insulin, mimicking
blockers,
the slow, steady
clonidine, lithium
(basal) secretion of
or alcohol may
insulin provided by
either potentiate
a normal pancreas.
or weaken the
LANTUS® may
effects of insulin.
need to be
Pentamidine may
prescribed in
 combination with cause
mealtime insulins or hypoglycemia,
oral hypoglycemic sometimes
agents. followed by
hyperglycemia.

Generic Name: nonsteroidal anti- *used to treat pain contraindicated in *chest pain, *a blood thinner *Do not drink alcohol
Celecoxib inflammatory drug or inflammation patients with known weakness, shortness such as warfarin while taking celecoxib.
Brand name: that exhibits caused by many hypersensitivity to of breath, slurred (Coumadin); Alcohol can increase the
Celebrex antiinflammatory,an conditions such as celecoxib. speech, problems risk of stomach bleeding
*diuretics (water
algesic, and arthritis, ankylosing *should not be with vision or caused by celecoxib.
pills) such as
antipyretic activities spondylitis, and given to patients balance; *Do not use any other
furosemide
in animal models. menstrual pain. who have over-the-counter cold,
*black, bloody, or (Lasix);
The mechanism of *It is also used in experienced asthma, allergy, or pain medication
tarry stools;
action of the treatment of urticaria, or *fluconazole without first asking your
CELEBREX is hereditary polyps in allergic-type *coughing up blood (Diflucan); doctor or pharmacist.
believed to be due the colon reactions after or vomit that looks *Call your doctor at once
*lithium
to inhibition of taking aspirin or like coffee grounds; if you have symptoms of
(Eskalith,
prostaglandin other NSAIDs. *swelling or rapid Lithobid); bleeding in your stomach
synthesis, primarily weight gain; or intestines.
via inhibition of *a heart or blood
cyclooxygenase-2 *urinating less than pressure
(COX-2), and at usual or not at all; medication such
therapeutic as candesartan
*nausea, stomach
concentrations in pain, low fever, loss (Atacand),
humans, eprosartan
of appetite, dark
CELEBREX does (Teveten),
urine, clay-colored
not inhibit the irbesartan
stools, jaundice
cyclooxygenase-1 (yellowing of the skin (Avapro, Avalide),
(COX-1) losartan (Cozaar,
or eyes);
isoenzyme. In Hyzaar), valsartan
animal colon tumor *fever, sore throat, (Diovan),
models, celecoxib and headache with a telmisartan
reduced the severe blistering, (Micardis), or
peeling, and red skin
 incidence and *rash; or olmesartan
multiplicity of (Benicar); or
bruising, severe
tumors. tingling, numbness, *an ACE inhibitor
pain, muscle such as benazepril
weakness.

Generic Name: an osmotic diuretic *is used to force *Pulmonary *dry mouth, increased Increased *The medicine must be
Mannitol that is metabolically urine production in congestion or thirst, blurred vision, nephrotoxicity given slowly through an
inert in humans and people with acute oedema; or seizure with ciclosporin. IV infusion, and you may
Brand names: occurs naturally, as (sudden) kidney * intracranial (convulsions); receive the medication
Osmitrol, Resectisol a sugar or sugar failure. Increased bleeding; around the clock.
*swelling, pain, or
alcohol, in fruits urine production *CHF; metabolic * Follow your doctor's
skin changes where
and vegetables. helps prevent the oedema with instructions about any
the medicine was
Mannitol elevates kidneys from abnormal capillary restrictions on food,
injected;
blood plasma shutting down, and fragility; beverages, or activity
osmolality, resulting also speeds up *anuria due to *chest pain, fast heart while you are being
in enhanced flow of elimination of severe renal rate; treated with mannitol.
water from tissues, certain toxic disease; *feeling like you
including the brain substances in the *severe might pass out;
and cerebrospinal body. dehydration.
fluid, into *feeling short of
*is also used to breath, even with
interstitial fluid and reduce swelling and mild exertion;
plasma. and other pressure inside the
solutes. *swelling, rapid
eye or around the
brain. weight gain; or if you
stop urinating.
Less serious side
effects may include:
nausea, vomiting;
runny nose;
chest pain, pounding
Generic Name: *blocks the action *is used to treat *contraindicated in *heartbeats or *digoxin(digitalis *You should not use this
metoprolol of the sympathetic angina (chest pain) sinus bradycardia, fluttering in your , La noxin); medication if you are
nervous system, a and hypertension heart block greater chest; allergic to metoprolol, or
*clonidine
portion of the (high blood than first degree, if you have a serious heart
*feeling light-headed, (Catapres);
Brand names: involuntary nervous pressure). cardiogenic shock, problem such as heart
fainting;
Lopressor, system, by blocking *It is also used to and overt cardiac *ritonavir block, sick sinus
Metoprolol beta receptors on treat or prevent failure *feeling short of (Norvir); syndrome, or slow heart
Succinate ER, sympathetic nerves. heart attack. breath, even with rate.
*terbinafine
Toprol-XL, Since the mild exertion; *
(Lamisil);
Metoprolol Tartrate sympathetic *swelling of your
nervous system is *a diuretic (water
hands or feet;
responsible for pill);
increasing the rate *nausea, upper *cold medicines,
with which the heart stomach pain, itching, stimulant
beats, by blocking loss of appetite, dark medicines, or diet
the action of these urine, clay-colored pills;
nerves metoprolol stools, jaundice
reduces the heart (yellowing of the skin*anti-malaria
rate and is useful in or eyes); medications such
treating abnormally as chloroquine
* easy bruising,
rapid heart rhythms. (Aralen) or
unusual bleeding hydroxychloroqui
(nose, mouth, vagina, ne (Plaquenil,
or rectum), purple or Quineprox);
red pinpoint spots
under your skin; *bupropion
* wheezing, trouble
breathing;
*depression,
confusion, memory
problems,
hallucinations; or
*cold feeling in your
hands and feet.
Generic Name: a long acting *used to treat high contraindicated in *feeling like you *In Vitro Data *Drinking alcohol can
Amlodipine calcium ion blood pressure patients with known might pass out; *Cimetidine further lower your blood
antagonist, is the (hypertension) or sensitivity to *Grapefruit Juice pressure and may increase
active ingredient in amlodipine. *swelling in your *Magnesium and
Brand Names: chest pain (angina) certain side effects of
Norvasc Norvasc (Pfizer) and other conditions hands, ankles, or *Aluminum amlodipine.
and Lotrel caused by coronary feet; *Hydroxide *Take amlodipine exactly
(Novartis). artery disease Antacid as prescribed by your
*pounding
Amlodipine inhibits *Sildenafil doctor.
the transmembrane heartbeats or *Atorvastatin *Take this medication by
influx of calcium fluttering in your *DigoxinEthanol mouth, usually once daily
ions into vascular chest; or (Alcohol) with or without food or as
smooth muscle and *Warfarin directed by your doctor.
cardiac muscle. The chest pain or
* The dosage is based on
drug binds to heavy feeling, pain
your medical condition
dihydropyridine and spreading to the and response to treatment.
nondihydropyridine
arm or shoulder,
binding sites.
*nausea, sweating,
general ill feeling

Generic name: CDP-choline *Age-related *it must not *Itching or hives, *it potentiates the
Citicoline supplements memory problems. administered to swelling in your face effects of L-dopa
increase dopamine Citicoline seems to patients with or hands,
Brand name: receptor densities, help memory loss in hypertonic of the *swelling or tingling
and suggest that people aged 50 to parasympathetic in your mouth or
CDP-choline 85 years. throat,
supplementation *Stroke recovery. *chest tightness,
can ameliorate *Long-term blood trouble breathing, or
memory impairment circulation rash.
caused by problems in the
environmental brain
 conditions

Generic Name: Inhibits bacterial *Treating mild to *Hypersensitivity to Least effect: *Aminoglycoside *Take Cefpodoxime by
Cefpodoxime cell wall synthesis moderate infections cefpodoxime, any *Diarrhea; headache; s (eg, mouth with food.
by binding to one or caused by certain component of the loose stools; nausea; gentamicin), *Cefpodoxime works best
Brand Name: more of the bacteria. formulation, or upset stomach; cyclosporine, or if it is taken at the same
Vantin penicillin-binding other vomiting. diuretics (eg, time each day.
proteins (PBPs) cephalosporins Severe effect: furosemide, *To clear up your
which in turn * Severe allergic hydrochlorothiazi infection completely, take
inhibits the final reactions (rash; hives; de) because the Cefpodoxime for the full
transpeptidation itching; difficulty risk of side effects course of treatment.
step of breathing; tightness in on the kidney may * Keep taking it even if
peptidoglycan the chest; swelling of be increased you feel better in a few
synthesis in the mouth, face, lips, days.
bacterial cell walls, or tongue); bloody *Cefpodoxime should not
thus inhibiting cell stools; seizures; be given within 2 hours of
wall biosynthesis. severe diarrhea; skin antacids or H2 antagonists
Bacteria eventually rash; stomach (eg, famotidine).
lyse due to ongoing pain/cramps; vaginal
activity of cell wall irritation or discharge.
autolytic enzymes
(autolysins and
murein hydrolases)
while cell wall
assembly is
arrested.
Generic Name: *Elevates the serum *an essential body *Hypersensitivity *constipation; *acetohydroxamic *Take ferrous sulfate on
Ferrous sulfate iron concentration mineral. • Severe acid (Lithostat); an empty stomach, at least
*upset stomach;
which then helps to * used to treat iron hypotension. *chloramphenicol 1 hour before or 2 hours
Brand Names: form High or deficiency anemia *black or dark- ;cimetidine after a meal.
Feosol, Fer Iron, trapped in the (a lack of red blood colored stools; or (Tagamet); *Avoid taking antacids or
Fer-Gen-Sol, Fer- reticuloendothelial cells caused by *temporary staining *etidronate antibiotics within 2 hours
in-Sol, Fer-Iron, cells for storage and having too little iron (Didronel); before or after taking
Feratab, FeroSul, eventual conversion in the body). of the teeth. *dimercaprol (an ferrous sulfate.
Ferra-TD, Ferro- to a usable form of injection used to *Take ferrous sulfate with
Bob, Lydia E. iron. treat poisoning by a full glass of water.
Pinkham, MyKidz arsenic, lead, or * Do not crush, chew,
Iron 10, Slow Fe mercury); break, or open an
*levodopa extended-release tablet or
(Larodopa, capsule.
*Dopar, Sinemet); *Swallow the pill whole.
*methyldopa *Breaking or opening the
(Aldomet); or pill may cause too much
penicillamine of the drug to be released
(Cuprimine). at one time.
*Advise patient to consult
physician if irregular
heartbeat, dyspnea,
swelling of hands and feet
and hypotension occurs.
Generic Name: inhibit a protein *used to treat and *contraindicated in *headache; *ampicillin *Take lansoprazole
Lansoprazole called the prevent stomach patients with known (Omnipen, exactly as prescribed by
*nausea, stomach
hydrogen-potassium and intestinal severe Principen); your doctor.
pain;
Brand names: ATPase, which is a ulcers, erosive hypersensitivity to *atazanavir *Lansoprazole is usually
Prevacid, Prevacid molecular pump esophagitis (damage any component of *diarrhea; or (Reyataz); taken before eating.
OTC, Prevacid that moves to the esophagus the formulation of constipation. *clopidogrel *Follow your doctor's
SoluTab, Prevacid hydrogen ions into from stomach acid), PREVACID. (Plavix); instructions.
I.V. the stomach and and other conditions *digoxin *Do not crush or break a
transports involving excessive (Lanoxin, lansoprazole delayed-
potassium ions out stomach acid such Lanoxicaps); release capsule.
of the stomach. The as Zollinger-Ellison *ketoconazole *Swallow it whole.
hydrogen ions that syndrome. (Extina, Ketozole, *Breaking the pill may
this protein pumps Nizoral, Xolegal); cause too much of the
into the stomach are a blood thinner drug to be released at one
needed for the such as warfarin time.
stomach's natural (Coumadin); *If you are unable to
acidity, which is *iron (Feosol, swallow a lansoprazole
important for Mol-Iron, Fergon, delayed-release capsule
digestion and for Femiron, others); whole: Open the capsule
the activation of or and sprinkle the medicine
other proteins. *theophylline into a spoonful of
(such as pudding, applesauce,
Elixophyllin, yogurt, cottage cheese,
Respbid, Slo-Bid, strained pears, or a
Theobid, nutritional drink such as
Theoclear, Theo- Ensure.
Dur, Uniphyl).