Volume 2, Issue 1

Table of Contents
Coming Soon: Online MTA Form 2

Tip of the Quarter: Guidelines for Faculty Consulting
The UC encourages outside faculty as export control, intellectual property and submission of research grants, and activities, such as consulting, that contribprovides sample language that can be ute to the individual’s profession, to the included with a faculty’s consulting community and to UCLA’s teaching and public service mission. To this end, a agreement. revised and updated Guide to Remember, consulting agreeFaculty Consulting Activities This guide will help ments are personal agreeand Consulting Agreements faculty navigate ments between an outside was distributed in September. conflict of comments organization and the consultThe updated guide is posted ant, to which the University and conflict of to http://www.oip.ucla.edu/ is not a party. Under the academic-community/ interest concerns circumstances, UCLA staff policies-and-related-forms. cannot provide faculty with We anticipate faculty may use furlough time and this guide will help faculty navigate conflict of commitment and conflict of interest concerns. These issues have become subject to increased scrutiny by the University, the State of California, Congress, federal agencies, and the general public. Therefore, it is important that consulting be done in a way that does not interfere with a faculty member’s primary commitment to the University and that it is accomplished within the framework of University policies. The guide also covers topics such personal legal advice, nor can they act on behalf of individual faculty to negotiate the terms of a consulting agreement. As a courtesy however, staff of both the Office of Intellectual Property & Industry Sponsored Research (OIP-ISR) and Legal Affairs – UCLA Health System will be happy to answer questions about individual consulting agreements and whether it is consistent with University policy. For questions related to faculty consulting, please contact OIP-ISR at (310) 794-0558 or Legal Affairs – UCLA Health System at (310) 794-3138.

Student Inventor Spotlight: Alejandro Covalin “Mind over Matter”


Meet the Staff—Technology Transfer Associates


Newly Issued UCLA Patents for 3 3rd Quarter, FY2009

Things to Come … ISR Checklist


Be Fair: Defining Fair Use


Kathryn’s Korner
Welcome to another year and another issue of The Inventor newsletter. As the academic year kicks off, our new issue contains stories on innovative developments at UCLA, a look at one of our new student inventors, and new information on faculty consulting. We have launched a redesigned website, www.oip.ucla.edu, to further facilitate our collaborations with the faculty, staff, and students at UCLA as well our partners in the business community. Check out our yearly magazine, UCLAInvents which highlights some of the great inventions and ideas coming out of the UCLA campus. A full copy is available on our new website at http:// www.oip.ucla.edu/publications/UCLAInvents2009.pdf. I hope that this new academic year continues to bring forth the innovations for which UCLA is known. We are here to help. Sincerely, Kathryn Atchison, D.D.S., M.P.H.
Vice Provost, Intellectual Property and Industry Relations Associate Vice Chancellor for Research

Volume 2, Issue 1

Coming Soon: Online MTA Form
A new feature for material transfer requests, “onlineMTA” will be a central site for submitting all requests for Material Transfer Agreements through a new, convenient web-based form. The onlineMTA site will also allow investigators to track the status of their pending and completed MTA requests submitted after July 1, 2009. To facilitate the transition to this new MTA request process, training for the new onlineMTA portal is being made available. Faculty, research staff, lab managers, and administrative staff are welcome to join the MTA team for a training session on the new system. The class will be held on December 3rd, 2:003:00 p.m. in the Ronald Regan Medical Center, Room 3-3102. For further questions, or to RSVP for this training event, please contact the MTA team at UCLAMTA@research.ucla.edu.

Student Inventor Spotlight: Alejandro Covalin Mind over Matter
Having earned an undergraduate degree in physics engineering at Universidad Iberoamericana in Mexico City, Alejandro Covalin began his professional life working as a new projects engineer in the forestry industry in his native Mexico. At first, he found the Alejandro Covalin work both challenging and satisfying. But after overseeing the design and construction of a new sawmill facility, Covalin recalls that he felt the need to move on. “I wanted to go back to school,” he says. “I applied to various schools and between Berkley, CWRU and UCLA, I was most excited by what UCLA had to offer; basically, I liked their approach and the freedom I would have to choose my thesis subject; I accepted and started working on my PhD in neuroengineering.” Covalin came to UCLA in 2000 and, under the guidance of Associate Professor Jack Judy, he quickly focused on the study of feedback mechanisms in the autonomic nervous system. It was something of a leap from pure engineering and machinery design to the anatomy of the nervous system, Covalin admits, but his background in physics and engineering ultimately served him well. “There is a lot of physics involved in how the nervous system works. Having been trained as an engineer, I had to retrain myself to learn and think differently in order to force my mind to blur the boundaries between engineering and neurosciences, which in itself is neuroengineering.” Advised by UCLA Neurosurgeon Professor Antonio De Salles on viable applications of his knowledge to clinically relevant issues, Covalin ultimately turned his attention to the problem of obesity and the role the autonomous nervous system plays in determining metabolic rates. He found that there is in fact a region in the brain that controls metabolic activity, and that by introducing an electric current, it is possible to regulate metabolic rate. Having successfully demonstrated the technology on rats, Covalin and Judy, together with Los Angeles-based entrepreneur Leon Ekchian, a UCLA graduate with an MBA from the Anderson School, and UCLA neurosurgeon Antonio De Salles founded NeuroSigma, Inc. in 2008. NeuroSigma exclusively licensed the patent application from UCLA, is currently

“Covalin” Continued on Page 4

Meet the Staff—Technology Transfer Associates
ULCA Alums both, Lindsay Keever and Brian Shedd both found their way to OIP and are the office’s Technology Transfer Associates, positions for scientists to break into the Technology Transfer career. As Tech Transfer Associates, their role is to evaluate the patentability and potential commercial applications of inventions, plan marketing and patenting strategies, and assist PIs in finding commercial partners to help bring their technologies to market to benefit society and the economy. “advanced technology and business” where he could “walk the line between the two arenas”. For both, this interest in the duality of their positions allows them to successfully work with potential corporate partners for UCLA technologies as well as form successful relationships with UCLA faculty and students.

Though working with different areas of scientific expertise, both agree that UCLA’s faculty bring exciting developments to the forefront and the enjoyment of their jobs comes from helping to find ways to progress Lindsay Keever Brian Shedd the development of these technologies into Having received an MS in Biochemistry and potential commercial products. In helping to build bridges with Molecular Biology, Lindsay was drawn to “the business side of science” and found herself at OIP working daily with PIs and their the external corporate community, Brian says we “would like to know what other ways faculty and students would like to be able groundbreaking technology. Brian recently earned a Ph.D. in to interact with that community”. For these Bruins, it is the Mechanical Engineering from UCLA and, after a marketing relationships developed at UCLA that allow them to be so internship with OIP, found a fulltime position working with successful at their jobs.

Volume 2, Issue 1

Newly Issued UCLA Patents for 3rd Quarter, FY209
Case No.

Invention Title
Transcription amplification system for molecular imaging Nano-scale computational architectures with spin wave bus

Inventors by Last Name
Michael Carey, Sanjiv Gambhir, Meera Kodukulla, Lily Wu, Liqun Zhang Alexander Khitun, Roman Ostroumov, Kang-Long Wang

Department Patent No.
SOM 7527942

2005-021 1999-574 2000-462 2002-466


7528456 7532669 7531514 7531649 7531355 7534440 7534764 7535070 7537905 7541600 7544398 7544966 7544486 7547932 7548910 7550571 7553484 7553143 7554111 7557194 7557372 7567715 7569542 7579319

Video codec method in error resilient mode and appaJohn Villasenor, Jiangtao Wen ratus therefor Orally administered peptides synergize statin activity Alan Fogelman, Mohamad Navab

Aptamers to human epidermal growth factor Chi-Hong (Betty) Chen, Ralf Landgraf receptor-3 Methods and compositions for smooth muscle recon2004-084 Larissa Rodriguez, Benjamin Wu struction Fusion molecules and methods for treatment of imAndrew Saxon, Ke Zhang, 2000-262 Daocheng Zhu mune diseases Competitive regulation of hepcidin mRNA by soluble 2005-604 Tomas Ganz, Lan Lin and cell-associated hemojuvelin 2006-385 2002-341 2005-521 2003-317 2004-248 2004-331 2002-421 2003-357 2000-122 2000-118 2004-433 2004-561 Spin-wave architectures Amplified and overexpressed gene in colorectal cancers Mary Eshaghian-Wilner, Alexander Khitun, Kang-Long Wang Lee Anderson, Charles Ginther, Dennis Slamon

Lithographic and measurement techniques using the Daniel Neuhauser, Gabriel Sirat optical properties of biaxial crystals Controlled nano-doping of ultra thin films Three-terminal electrical bistable devices Nell peptide expression systems and bone formation activity of nell peptide Vertical gate-depleted single electron transistor System and method for retrieving scenario-specific documents Lafora's disease gene Modulating neuronal outgrowth via the major histocompatibility complex class I (MHC I) molecule Lobe pump system and method of manufacture Nanoparticle-polymer bistable devices Jane Chang, Trinh Tu Van Jun He, Liping Ma, Yang Yang Shunichi Kuroda, Kang Ting, Benjamin Wu Filipp Baron, Kang-Long Wang, Yaohui Zhang Wesley Chu, Victor Liu, Qinghua Zou Antonio Delgado-Escueta Lorraine Hanssen, Daniel Kaufman, Daniel Zekzer Shih Hsi Tong, Daniel Yang Richard Kaner, Yang Yang Jonathan Braun, Christopher Sutton Jianyong Ouyang, Yang Yang Charles (Cheng-en) Guo, YingNian Wu, Song-Chun Zhu Randal Eckert, Fengxia Qi, Wenyuan Shi Alan Fogelman

1999-558 Antibody materials for an IBD-associated polypeptide 2003-194 2004-563 1999-543 2005-227 Memory devices based on electric field programmable films System and method for representing and encoding images Anti-microbial targeting chimeric pharmaceutical Methods for improving the structure and function of arterioles

Volume 2, Issue 1

Now Available: ISR Checklist
Researchers on the UCLA campus who are contemplating a research project and would like to submit a proposal to OIP-ISR now have a faster and easier way to do so. The ISR team has created a Proposal Checklist Form that researchers are able to complete and submit along with their proposal documentation. This checklist streamlines the way that researchers inform OIP-ISR of their potential research projects by (a) incorporating needed information onto one form, (b) reminding PIs of the additional proposal documents required, and (c) allowing PIs to submit all required documentation to a dedicated email inbox that is monitored by the ISR team. This checklist not only helps researchers carefully think through their proposal, but condensing a multi-step process into a single form will expedite the contracting process for PIs. The form is available online at: www.oip.ucla.edu/isr. All documents must be submitted before ISR will open formal negotiations with a sponsor. If you have questions, send an email to the ISR team at ISR@research.ucla.edu.

Be Fair: Defining Fair Use
Faculty and students often like to use the works of others within their own works, whether it is for teaching purposes or supporting documentation in research papers. As the slew of plagiarism stories in the news has recently indicated, the misuse of someone else’s work of authorship has serious consequences. permission from the copyright owner. What is the effect of the market? If your use of the work takes away potential royalties or sales from the original work, it is likely that you would need to get permission to use the work. However, if the original work is unavailable, there is no market for the work, or, if you are unable to identify or locate the original As an educational institution, UCLA copyright owner, it is more relies on the doctrine of Fair Use, likely that your use will be conAs an educational which states that “the fair use of a sidered a fair use of that work. copyrighted work...for purposes institution, UCLA relies Examples of fair use include such as criticism, comment, news on the doctrine of photocopying an article or picreporting, teaching (including Fair Use. ture for class and providing a multiple copies for classroom use), link to an online article for your scholarship, or research, is not an students. Since these items are being used for infringement of copyright.” an educational purpose, they typically fall under To determine whether use of a work fair use. However, photocopying an entire 300 fits under this description, the law outlines four page book for class probably will not quality as factors to help determine fair use: fair use because it might prevent the sale of a What is the character of the use? If book and that has a negative impact on the your use of the work falls under Non-profit or market for the work. educational uses, it has met the first criterion for If you have any concerns, OIP has a link to a fair use. If the use is commercial, it is best to template form that you can complete and send seek permission from the copyright owner first. to the publisher to ask permission to use the work. See www.oip.ucla.edu/copyright. Faculty How much of the work will you use? can also talk to the UCLA Library at 310-825The more of the work that you use, the more 1201 since they may have preexisting likely you are to need permission to use it. agreements with the publisher. If your What is the nature of the work to be department receives requests to use work that used? Works that are fact based, or previously belongs to the UC Regents, send an email to published typically fall under fair use, but highly copyrights@ucla.edu and OIP will handle the imaginative or creative work, or work that has permission request. not been published before tends to require

Covalin, Continued
taking steps to obtain FDA approval for human clinical trials and is moving forward with plans to commercialize the technology. Covalin believes that eventually, the company will go to market with a pacemaker-like device that can be used to treat obesity and other disorders. “The electrodes will go inside the brain,” he explains, “and the device that makes the pulses will be imbedded in the skull, functioning as an unperceived pacemaker for brain activity. UCLA offered to Dr. Covalin the environment for integration from the most basic scientific knowledge to the highest level of medical research. The consequent spin off, Neursigma, Inc., is a unique example of the superb entrepreneurial and scientific integration of engineering, biology and clinical practice at UCLA.

Subscribe / Contact Us
11000 Kinross Blvd., Suite 200 Los Angeles, CA 90095 www.oip.ucla.edu If you would like to be on the mailing list for future newsletters, please email Robin Faria at rfaria@conet.ucla.edu.

Publisher: Kathryn A. Atchison Executive Editor: Robin Faria Graphic Design: Ann Hu With special thanks to: Dayton Fandray

© 2009 UC Regents

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