You are on page 1of 16

c

Ê 
      
Ê   


 !"# $

% &'( !  Ê!"%

"& )
„    odontogenic fibromyxoma
 
  
 
  

odontogenic myxoma

 

    
 

 
  

  

 
   
 

 

 
  

 

  

 
 
„  
  

   




 

 

 
   

  
 
germ-cell
  

 




  

  
 



 

 





 
 

  
 

  

 


  

    
 
  

   
 
   




  
 
  

 
 
  
 
 !


   

   
"  
 


 
 

  
# 

  
   


 

  
 


$ 

 Ô 

 
 

  
  

 

 


  

  


 

 
 
   
%
 
 
  

  
 

 
  
 


& 
 '
(
 

   
 
 


Y 
„ibromyxoma/mixofibroma/odontogenic fibromyxoma or often also called odontogenic
myxoma is a neoplasm that is characterized by the existence of star cells (stellate) and spindle-
shaped cells contained in mixoid tissue which also contains many collagen fibers. „ibromyxoma
is an odontogenic tumor are very rare, and are derived from mesenchymal tissue that is part of
the tooth germ-cell. These tumors can occur in several locations such as heart, jaw bone and
skeletal muscle. Very rare in the head and neck region. The tumor is bounded firmly
encapsulated, can infiltrate the adjacent structure, and has a potential for extensive bony
destruction.
„ibromyxoma incidence varies in different countries, the range is between 30-20% of all
odontogenic tumors. Prevalence is greatest in the third and fourth decade of life. The everaget is
30 years old, and most occur in women.
It was reported one case of fibromyxoma in left maxillary sinus cavity that extends to left
nasopharynx and oral cavity in a man aged 26 years. Management has been carried out with a
enucleation/extirpation tumor surgery.

Keywords : fibromyxoma, odontogenic tumor, sinonasal, extirpation


O

Ê 

 „    odontogenic fibromyxoma


 
  
 
  

odontogenic myxoma

 

    
 

 
  

  

 
   
 

 

 
  

 

  

 
 )*
„  
  

   




 

  


 

 
   


  
 
germ-cell
  )%
 




  

  
 




 

„  




 
 

  

„  
  

 
   

 
  
 
 

 
 
„

" + ,
 
%
 
 

   

,%
 

   
  

  

 



  

 
 


  
 


„  
  

  
   


 


   

   

 

   


  



 

  
  
   
 
   



  

  
   
   %
 


  

  
  
  


  
 

 

  

 

  -
.
  


 
 
  
 

   
 

  


    
 

)/

0

 
  
 
odontogenic fibromyxoma-associated calcifying cystic

odontogenic tumor 112



 
   
 
),
 

    
 





  
 

  
.
 

 
 

   


   
   

   
 





 
  
3 
  
  


  
 


  

$

 
  

"  
 
 
 
 

  
 
 
 

„  

 

   

  
 

   
 

  
  
 
"


 
 
 

 
 
 

%
 
 
 

  
  

 

 
  

  



  

  

  
  
 
 


  /-

  Ê

 
  
 
  

 
 
  
 
 !


   

   )
 

  

   
 

 

 

  
4  
 
   
  
 
)/
 
"  

 


 
 

  %
# 
  
   


 


  
 


$ )*5
6 
/,!
 
  


 
 


 



 

 
,
 
 

$
)
 )

  

3 
 
  
 
 

  
0 

 
 $

 

  
  

  )

"   
 
  



  
  
Ô 
 
  
 
 

 
  


 

 
  

  *))

#
   

„  

   
 ' 
  
   
 

 


   
   
 


   
  
„  

 

  
  
 
  
  
  
 
 
.
  

   

   
  
 
   


   


*soap bubble´
 
*honeycomb´
 
   
 

  
 
  
 

 

 
  


 
„  

 

   

 
   )*

Ê #   

7 
    
 
 

 

 
   

  
"  
 
 
  
  
 '
 ,
8  
)
   


     
 

 
  

 
   


9 
  

 

   
   
   :

;

< )
 
  

 
=+  )*
   

$
 
  


spindle cell

 
  
  


  
  
  


   

 
 
.+ 

" '),
   
 

  
  

  
  
 

cytoplasmic inclusion bodies

 

 
    
"   


 
   
$
 
  


   
 
 
 
Gs alpha gene (239).)

Ê  # 

.
   
 
 

  
  
 

spindle shaped

cell
 
 
   

 '

3  
 
  

 
  

 
  

  
 

 

   

 


 
 
  

 
 
  
3  
 
   
 

  
 
 
"   
    
   
$
  


 
  


   

  

 

   
„  
 '
  
  
 
  
 
   
  

  
 

 
 

 

 
  
„  
 
  

  
 
 
 
„  
 
  
 

 
 

 
  

malignant fibrous histiocytoma

  ),

 #  

 |  

 
   
  
 

 
  


  

 
 
.
MRI
  
 
  
CT scan
 

   
  
 
 
 

 
 '
 

   
 
 
   
 
,

3 '
  
 


 



  

   
    
 
 

 


| 
  
 

   

   
"
  
 


 '

 

  
  
 

 
 %/


2

 #  
 #

 3 '
  
 
   
 
 
  

chondromixoid fibroma
low-grade myxoid fibrosarcoma


  

 )*

Ê 

"  

  

 
 
 
 

   

 
 
  %

7 
  

 
 
 
   
,%

7 

   
 ' 

  
 '
 
 
  


 
 
  
   
 
  
 

   
  
 
  

  
 
 

   
,!


   
 

 
 

 
  
 
  


 
  

 

   -)%

4  
 
 
   
   
 
   
 
   
 
graft

 


  
 
   )/

"  
 

  
 
   

 

  

 
 
 
 
3  
  
   
 
 

  
74>
 
1'
   
  

 
 
 
  
 
  

   
" 
 
 
  
  
  

follow-up
 
  

Ê #  

 

 ' 

  
 
   
 
 



 
  
 

 
 
 

  
 '
  

,!
 
 

 
 
&  
  
   
 



  



 
 
 
  
&  


 
  



 
)*
3 

6  )-)5
  
$
  

  


   
   
 
 
 
  



   

 

 
 

  
 
 

Ê 

 3 
  


 
%
 

 

 
 
 
 





7
 )
 
  

 

 

 
  

 


  
 
   
  

  
 

 

 
  
 



   
 
 
 

" 
   
 
 

 

 
  

 


$
 
 
 

 

 
? 

 
 
 
   

 



  

 
 
)
 

 
" 
 
   
  

   
 
)
 

 
&  
  
 

 
   

 

" 
 


6

 
 
  
 

 

 
  

 
 

 
  

 
  
 
" 
 
   

 



  
 
 


  

"
   
 
  


 

  
 

  

 

  
  
 
 
$
  
 
 
  
 

'
@
),

'
@
)
'
Ô  


 
 
  





 



   
7

 

 
 $
 
 
 ' 


  
 
   


  
    



  


palatum molle

durum  
 

 

 

   


 

'

.
)
" 
 
   
 

  

 
  
'
 


Ô
 
   
 
 
"
 
  


)/
„  

 )

  


 

   
  
 
  
 
 

 
  
'  
 

 
 

 

6 
"
 
  


,
7
 )

inflammatory polyp nasi

"   
CT scan


)
7
 )
   




 

  
  
   

   


  

 
  

  
   
7
    

  
  
   
  
 
 


 

   
3  




 
 


 


"

)5
7
 )
 
   
 

"
   
 

  
 
  
  
  
  


)
7
 ) 

"'
  
 

  
 

 
'
 
 

.

" 
 
'
  

6 
 
 

)
7
 )


 

  

 


inflammatory polyp
 

   
3   
 
CT scan
  

3"|


-
A 
 )



 

  
   
   
  

  

  
  
  
 
 
  

  
  
  

 
  

 
  

3  


)5
  
 )
  
 
 

 

2 
  
  
 


>  
  

   
  

  

 

  

   
 

  
  
  

  
 
  


 


  

  

 


sulcus buccogingival

  
7
 $
 
   
 

  
  

 
  
  
 
  
7
  
 


    
 




  
7
  
 '
   
 
 
 
sulcus

buccogingival

  
"'
 
  


 '
    

   
  
 
)
@
%
@
,
'

c

'

.

Ô 
 







  
'

"'
 

 

   
' 
  
  
 


  
,!
  
  
Yminovel
)
 
  
   
  
   

@

,

  
   

@
),

  

 

 


@
,

  

 
 

@
)

  

„  

 6
  
'
 
  
 
 
 
 
 
 

 
 
 
 


  

  

  


  

  


 

  
  


  
  
 

"

 
 
'

6
  
'
 
  
  

  

  
  

  

  
 
 

 
  
 

sulcus buccogingival

  
3 
  

  


 

 



 






 
 


7 
 


  
  

 

  

 
 

  
'
 

 


  

 
 
 
 
 
  
'
 
  
  


  
  
  
 
  
 
*


cc

"'
 

 
  
  
 
  
 
  

  
 
 
*

"'
  

  

 

 


 
 
 
  
"   
 
  
   

 

tramadol

@
,

  

  
 
  

'

.
*
" 
 
'
  
 
  
  


 

sulcus buccogingival'

" 
   
 


  
'
 

 
 

 
 '
 

  
&6&0
43#"
Ô
7
6  
 
" 
  


   
  


 

@
,


 
' '
  
 

 

  
 


 
 

6 
   
   

*
  
 )
  
 
  

 
 
  

  
  
| 

 
   




)%
3   
 )
  
 
 
 

  
  


 
 
 

cO

.
,
?  
 
  
.
%
"   

.
/
3  
 


   
 +
  
 
  
 
 
 

 

 
  


  
   
  
  
  
 
   
 


   
 

   

  
 
    
  

  

  Ê
 


  
 
  

* @

* @
  
) @

7 
 
'
 
 
 


6


  



 



 


 

 

 


3 


  

  
" 



  
  
 

 


  
  

  
  
  
 
7 
 


  

  
 
 
  
 
   

"

 
  

' 

sulcus buccogingival
 

   

  
  

'

.
-
" 
 

 
'
 

  

 
 


 

'

  
 
'
 
 
 
 


6
 

  


 
6 
   
  
 
 


  
  
 
 


  
 
   

" 
  
  
  
   


cÿ


  

 
 
 
 
 
 
 
  
 


 ' 
 ''  
" 
 
  
 
 
 
 



  

  
  
  
   

  

„  
 
odontogenic myxoma
 
  
 
  



 

 

 

 
  

 


  



  
 
 
    

 

  
$



  
  
 
 

  
   
  
"

 


  
  

 


 
  

 


  

  

.
  


 
 

 
 
 
,
 
 


 '
   
 
 

 
  


 
   
„  

  

  
   


 

   


   

 
  
   
 
   



  

  
   
   %
„  

  

 
   




  
 
 
  
  
$

"

1 scan
  
   


  

 
  
  

   



    
  
  
   
  
 
 

 


   
6

  
 
  


  
   


 
 


   
   

 
  


"  


 

     
4  

   
 

  
  
 

  
 
 
 
  
   

   
 
   

   
  '
 
 
4  
   
 



 
 
 
 

  
&  


 

 
  

 
 
  
 

  
 


"  

  
 
 

 

 
 
 

 
   ' 
  
   
%)5

& 
  

 
 

 
 
   
%
 
6


  
 
  



  
 
 


 
,

 )5
"
 


  
 '


 '
 

 


   
  
" 

 
 
   



  

  

 
  
"  
 

  
 

  


 



 Ê

Ô 
  
 
 
 
 
%
 
 
 
 


 

  
  
   

   
  

$
  

  
7
 
  

  
  

 


   
  


  

  

 
  

 

" 

  
 

     

"'
 
 

follow-up

 
'
 
  
  
  
  


 


  
 
  
 '




 
    



 Ê

)‘ ? ' 

2 
=8
2   '
@@ 
>(
" 

.  '
6 


| '
 
8
6  
2 + 
1 ' 

  
? 
0
= 

A8
4 '
"
3
A
=
>41
" 
0
 ,(
)-5

‘ 3 $ 
"A
2   '
'     
>(
" 


6 

| '

1 

3 $ 
"A
=
3  
6   
 %(
)*,

‘ "  
„
2   '
 
>(
3  '
" 


6 

| '
? 
0

=
> 
6  ' 
| $
B
 /C
 =(
) )))

*‘ 3
A"
2   '
 
>(
1 


7@  ' 
" 
3

A"
= 
04
8'
."
=
7
 *C
=(
)*%

,‘ .
3
0  
3
„ 
.
4 
=
0
?
A„
„ @


  

' 
A|4

A
|  
)55-C
)5()/5D,

%‘ 3
6
= 
7
| 
7
„
=
2   '
@


   '
'


  
(
  
$ 
A
Ô 
4 
Ô 
1 
Ô 

" ' 
 5C
() ,

/‘  $


>„
6 
.
& 
7A
& 
3
0 $ 
77
„ @

 

3  
4 
)55)C
 (5,-

-‘ .  
3
.  
4
A

#
6
2   '
@
A&
3' ' 
 /C
5)(

5,

5‘ 7 

? 
7
3 
.&
„ @
@ 
> 
A
2 
6 


| '
3  
 *C
,%*(
5,

) ‘ & + 

Ô  +
„<
.  + 
.
7@

' (

 

)
' 
A

2
7@  '
3 
)55,C,(,)-)

c2

))‘ 1 
.

  
' 

 ' '
  
   '
' 
?
Ô 
A

)5/%C)*)(5)*

)‘ 8  
8
0 
Ô
=+  
„
7  
  ' 
@(
  
@   

   

 
 
1' 
)5/)C
/())%/D/

)‘ 
A
< 
3



@


 

 '
  C
 


'


  
  $
6 
| '
3 
)5-,C
/(*/5-

)*‘ =+  
„7
>  ' 
@(

  $

$

 

*
' 

A
1 

" 
)5%,C
*() *)

),‘ .+ 


7„
" '
A.
6 
 ' 
@

 '  
'  
<

2
)5% C
%())D/

)%‘ 3 
8.
6 
7&
0 
?7
1 

 

   '
  
>(

@ 



 
> 3 
8?3  C
)5-(
5,/

)/‘ 1 
1
1 
B4
0
A"
 
1
7@ 
@
  
$ 
$ 
  ' 


  
 '  ' (

'
  

"
3 
)55/C
5)(
-/5

)-‘ |$ 
Ô1

„1
. 
@


 
 
@
)5/-C
(
, 

)5‘ 7 
<
3 

7 
3
3 
Ô
" 
4
7 
   '
@


@ 

> 
A
2'
 ,C

)

 ‘ E  
0
1
40
| 





   
>(
6 
;
| '

3  2  


?  
?A
A
A
 
0  '
8  
;
8  

"   


* 
C
 %()*-)55