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The Complete Toxin Binder for Cattle

feed

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What are Mycotoxins ?

Mycotoxins are toxins


produced by Fungi

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Where do Mycotoxins came
from ?

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Where do Mycotoxins came
from ?

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Co-occurence of Mycotoxins

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Multiple Mycotoxicosis
Co-occurance of Mycotoxins is common in feed ingredients and complete feed. The
toxicity respose and clinical sign observed in animals when more than one Mycotoxin is
present in feed are complex and diverse. Mycotoxin combination exert a greater
negative impact on health and productivity of animals. These toxicological interactions
can be additive, synergistic or antagonistic. Combined interactions can result in
set of diagnostic ill effects that differ from the sum of individual effect. These toxin –
toxin interaction cause greater damage to the animal and silently kill huge productivity.

Mycotoxins Type of interaction

Aflatoxin +Synergistic
Ochratoxin A
Aflatoxin + T-2Synergistic
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Toxin
Damaging effect of mycotoxins

C attle feed is an excellent medium for growth of these moulds, with the risk of
fungal growth increasing rapidly when there are high level of moisture in the
air. When the feed is ingested and subsequently digested in gastro-intestinal
tract, mycotoxins are released from feed and absorbed across the intestine,
enter the blood stream and transported to various organs causing cellular
malfunctions.

Moistur Mycoxtins
e Feed is enters the
ingested blood stream
and
C Mould Produces transported to
attleFee develop mycotoxin various
d s s organs
Mycotoxin causing
s released cellular
Tempera
& malfunctions
ture
absorbed
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in intestine
Effect of Mycotoxin depends
upon…..

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Feed contamination

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Effects of Mycotoxins

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Effect of Mycotoxin

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Mycotoxin affects the immune system

• Aflatoxin, Fumonisin B1, Ochratoxin and Tricothecenes


–  viability and phagocytic ability of macrophages
–  motility and chemo taxis of neutrophils

DON may affect


immunoglobulin production
Monocyte

Neutrophil Click to edit Master text styles


s Second level
to edit Master text styles
Receiving DON
Third level

d level  IgA Fourth level


Fifth level
 IgG and IgM

rd level
ourth level
Fifth level
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Effect of Mycotoxin

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Mycotoxicosis in Dairy

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Carry Over of Aflatoxin in Dairy

Aflatoxin M1 is quite stable towards


normal milk processing methods
such as pasteurization, and if present 1616
Mycotoxins are everywhere
Fu
Vo mon
i
Tricothecene Zea mito sin
Oc role xin
hr
Aflatoxins atonon
Zearolenon xin
Ochratoxin
Aflatoxi
Aflatoxi Fumoni
ns
ns Zearale
sins
Fumoni
non
sin

But, comprehensive solution is


only here
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Comprehensive protective Solution
Solution to these limitation required just not mineral binders rather
comprehensive broad spectrum mycotoxin inhibitor, binder and bio-
neutralizer is required for effective control of Mycotoxin menace.

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Composition

Clays (Silicates)
Activated charcoals
Organic Acids

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Activated charcoal
v Charcoal is obtained by burning wood, nutshells, coconut husks,
animal bones, and/or other carbonaceous (carbon-containing)
materials.

v It is activated by heating it with steam to approximately 1000 oC


in the absence of oxygen (O2).

v A single gram of such material can have 400 to 1,200 m2 of


surface area, 98% of it is internal.

v A C is a relatively non-specific sequestrate with great potential as


an antidote for acute exposure to several mycotoxins.

v Different grades of activated carbon have variable effects in


adsorbing mycotoxins and other toxins.

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Activated Carbon in

v Pharmaceutical grade with a


particle size of 200 mesh.

v It is used as discoloring agent in


vitamin tonics.

v M B index of the 250 mg/g


indicates the mesoporosity which
adsorbs mycotoxins effectively.

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Organic Acids

The organic acids in Avsorb Forte


posses an inhibitory influence on
Mould growth and thus reduces further
production of Mycotoxins
Apart from Mycotoxins they also binds
pesticides & fertilizers in the feed
Calcium Montmorillonite
(Special Silicates)

v Posses a characteristic of 2:1 Layer structure.

v High surface area of 600- 800 sq.mt/gram.

v Non-expansible clay with high negative charge.

v Aflatoxins and Ochratoxins are positively charged toxins.

v High affinity for Aflatoxin B1 followed by Ochratoxins. Also


binding is rapid so removes from gut before absorbed.

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Calcium Montmorillonite
(Special Silicates)

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Characteristics Of An Effective
Toxin Binder

v Able to bind most of the toxins ●


present in feed.
v Binding efficacy should be retained ●
till the excretion of toxin
v Should have maximum surface area ●
for adsorption
v Should not bind other nutrients and ●
feed additives

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C
O
N
C
Provides toxin adsorbent properties of activated carbon and HSCAS
L
Ø

U Ø Is effective against a wide range of mycotoxins including Aflatoxin, Ochratoxin, T-2 Toxin , Fumonisin etc.

S Ø Is active against chemical /pesticide residues, bacterial endotoxins etc.

I Ø has stable formulation which is safe and reliable.

O Dosage : 1Kg/MT of feed

N
Pack size: 25 Kg

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Avitech Nutrition Pvt Ltd
GP-37, UDYOG VIHAR, SECTOR-18,
GURGAON, HARYANA, INDIA.
info@avitechnutrition.com
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