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Hexamethrine

Bromide, Viral Infection


Enhancement

Description
F or Research Use Only. Not for
Diagnostic or Therapeutic Use.
Purchase does not include or carry
H examethrine bromide (or 1,5-Dimethyl-1,5-
diazaundecamethylene polymethobromide) is a cationic
polymer (an anti-heparin agent) used to increase the efficiency of
any right to resell or transfer this infection (100 to 1,000 fold in some cells) with retroviral vectors in
product either as a stand-alone
cell culture. It does so by neutralizing the charge repulsion between
product or as a component of another
product. Any use of this product other virions and sialic acid on the cell surface.
than the permitted use without the
express written authorization of Allele
Biotech is strictly prohibited Features
1. It is a diagnostic tool in the selective functional studies of the
anterior pituitary and zona glomerulosa of the adrenal cortex.
Website: www.allelebiotech.com
2. It produces a nonspecific agglutination of red blood cells by
Call: 1-800-991-RNAi/858-587-6645
neutralizing the net negative charge of the red blood cells.
(Pacific Time: 9:00AM~5:00PM)
Email: oligo@allelebiotech.com 3. It is central to a sensitive, automated technique for the detection
of antibodies.

4. It is used enhance virus detection in the MuLV and MSV


Box 1 | Basic Info systems in vitro.

5. It also enhances the degradation of peptides on automated


Hexamethrine Bromide sequential analysis.
C13H32Br2N2 6. It is used to assay of heparin activity in vitro.
Cat No. Quantity 7. It has been use in hair-conditioning, skin-moisturizing, and skin-
ABP-SC-HEXBR01 1 ml; 10 mg/ml in sterile water softening formulas.

Storage:
ABP-SC-HEXBR10 10 ml; 10 mg/ml in sterile water
Extremely hygroscopic. Store in a cool dry location at 4-8°C for up
to 2 years.

References:

1. Lalezari, P.: A new method for detection of red cell


antibodies. Transfusion 8:372, 1968.
2. Kovacs, K.; Carroll. R.; Tapp, E.: Experimental hexa-
dimethrine necrosis of anterior pituitary. Lancet 2:919,
1964.
3. Lalezari, P. and Spaet, T.H.: Antiheparin and
hemagglutinating activities of Polybrene. J. Lab. Clin. Med.
57:868, 1961.
4. Lalezari, P. and Platt, N.E.: Detection of red cell
sensitization in acquired hemolytic anemia by the
Polybrene method. Bibl. Haemat. 38:125, 1971.
5. Lalezari, P. and Oberhardt, B.J.: Temperature gradient
dissociation of red cell antigen antibody complexes in the
Polybrene technique. Brit. J. Haemat. 21:131, 1971.
6. Manning, J.S.; Hackett. A.J.; Darby, Jr.: Effect of
polycations on sensitivity of BALD-3T3 cells to murine
leukemia and sarcoma virus infectivity. N.B. Appl.
Microbiol. 22:1162, 1971.
7. Tarr, G.E.; Beecher, J.F.; Bell, M.; McKean. D.J.:
Polyquarternary amines prevent peptide loss from
sequenators Anal. Biochem. 84:622, 1978.

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