ARTICLES AND COMMENTS FROM 2010

WRITTEN AND COMPILED BY NATHALIE PELLETIER

Vitiligo Corner 2010
Table of Contents
What is Vitiligo? ............................................................................................................................................................................................................. 4 What Causes Vitiligo? .................................................................................................................................................................................................... 5 Vitiligo Symptoms .......................................................................................................................................................................................................... 6 Life with Vitiligo ............................................................................................................................................................................................................. 7 Vitiligo Corner Posts 2010 ............................................................................................................................................................................................. 8 Does vitiligo make you feel lonely? ............................................................................................................................................................................... 8 First vitiligo world congress 2010 ................................................................................................................................................................................ 10 10 Comments ........................................................................................................................................................................................................... 13 Can forgiveness cure vitiligo? ...................................................................................................................................................................................... 15 2 Comments ............................................................................................................................................................................................................. 16 Vitiligo treatments: nbUVB and pimecrolimus ............................................................................................................................................................ 17 Iran ‘revolutionizes vitiligo treatment’ ........................................................................................................................................................................ 18 9 Comments ............................................................................................................................................................................................................. 19 Teen model’s vitiligo campaign.................................................................................................................................................................................... 21 2 Comments ............................................................................................................................................................................................................. 22 st. louis vitiligo support group meet-up....................................................................................................................................................................... 23 One Comment .......................................................................................................................................................................................................... 24 Skin transplant offers hope for vitiligo ........................................................................................................................................................................ 25 6 Comments ............................................................................................................................................................................................................. 28 Dr.Oz show, promising vitiligo concealing method ..................................................................................................................................................... 30 Hypochlorhydria, vitiligo connection? ......................................................................................................................................................................... 31 Comments ................................................................................................................................................................................................................ 34 Visit Vitiligo Corner Visit Vitiligo Cover Lotion Page 2

Vitiligo Corner 2010
Pigment disease ‘reduces cancer risk’ ......................................................................................................................................................................... 36 Vitiligo repigmentation success ................................................................................................................................................................................... 40 18 Comments » ........................................................................................................................................................................................................ 41 Vitiligo solution near with Avita’s “Recell”? ................................................................................................................................................................ 45 36 Comments » ........................................................................................................................................................................................................ 47 UV-protective drug to be tested for vitiligo ................................................................................................................................................................. 55 23 Comments » ........................................................................................................................................................................................................ 57 The drug development process – Part 1 of 3 ............................................................................................................................................................... 65 The drug development process – Part 2 of 3 ............................................................................................................................................................... 67 The drug development process – Part 3 of 3 ............................................................................................................................................................... 69 Interview with Clinuvel ................................................................................................................................................................................................ 71 10 Comments » ........................................................................................................................................................................................................ 76 What is segmental & non-segmental vitiligo? ............................................................................................................................................................. 79 What goes on during clinical trials? ............................................................................................................................................................................. 81 Is there a connection between gluten intolerance and vitiligo? ................................................................................................................................. 83 Can gluten be absorbed through the skin?.......................................................................................................................................................... 83 Vitiligo World Congress 2010 – thoughts and reflections ........................................................................................................................................... 85 38 Comments » ........................................................................................................................................................................................................ 87 Vitiligo can help us, help others ................................................................................................................................................................................. 104 6 Comments » ........................................................................................................................................................................................................ 106 About the Author ....................................................................................................................................................................................................... 107

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the cells which give the skin its color.Vitiligo Corner 2010 What is Vitiligo? Vitiligo is quite a common skin disease which affects at least 2 people in every 100 in countries throughout the world. rapidly or slowly.vitiligosociety. male or female. In some cases the white patches can spontaneously repigment. though about fifty percent of people develop it before the age of twenty. Some people may not notice a change in their condition for many years. particularly in children. The most common form of vitiligo appears in symmetrical form (generalized vitiligo) affecting both sides of the body. though it is rare for the disease to resolve completely without treatment. hands and genitals are affected. It is not infectious. irrespective of skin color or ethnic origin can develop the condition. Anyone. people with dark skin from certain ethnic groups who develop vitiligo may feel particularly stigmatized and fear a loss of identity should the disease become widespread.org. Vitiligo causes the skin. have either been damaged or destroyed. to turn white in patches. Although the disease is more noticeable on dark or tanned skin the degree of distress is not necessarily linked to skin color or to the extent of the disease. and sometimes the hair. In some cases only one half of the body is affected (segmental vitiligo) and this type has limited progression and is more difficult to treat. However. You cannot catch vitiligo. The disease can spread. Although there are no physical symptoms apart from sunburn in the white patches if they are not protected from the sun. This is because melanocytes.uk Visit Vitiligo Corner Visit Vitiligo Cover Lotion Page 4 . it can cause severe psychological distress. http://www. Vitiligo can begin at any age. to cover the entire body surface (universal vitiligo) but this is not inevitable. neck. The course of vitiligo is unpredictable. while for others it can spread quite rapidly. especially when the face.

or who have family members who suffer from vitiligo or these diseases. We know that pigment cells are not functioning in the white patches although some of them do survive both in the skin and also in the hair follicles in the white patches. hormonal changes including puberty and childbirth. and even exposure to certain chemicals may trigger the disease and could play an important role in its development and progression. in particular thyroid disease. It is also recognized that environmental factors such as psychological stress. Other theories which have been proposed include the neuronal theory which suggests that the nerves in the skin are implicated in the damage to pigment cells and the oxidative stress theory based on the breakdown of anti-oxidant defenses in the skin or in the pigment cell itself. http://www.uk Visit Vitiligo Corner Visit Vitiligo Cover Lotion Page 5 . especially those who have other autoimmune diseases. trauma to the skin.vitiligosociety.org. In addition. It has also been recently established that genes play an important role in predisposing some people to vitiligo. Many theories exist to explain the loss of pigment. high levels of hydrogen peroxide which is toxic to pigment cells have been found in the skin of people with vitiligo. the most popular is the autoimmune theory which means that the body’s own immune system is attacking the pigment cells. This discovery strengthens the autoimmune theory.Vitiligo Corner 2010 What Causes Vitiligo? We have some idea of what is happening in vitiligo but are less clear about why it is happening.

such as your hands. * Segmental. The natural course of vitiligo is difficult to predict. * Generalized. Vitiligo generally appears in one of three patterns: * Focal. depigmentation usually develops first on sun-exposed areas of your skin. feet. In other cases. Loss of skin color occurs on only one side of your body. Other less common signs may include: * Premature whitening or graying of the hair on your scalp. Although it can start at any age. Pigment loss is widespread across many parts your body. face and lips. Sometimes the patches stop forming without treatment. pigment loss can involve most of the surface of your skin. Depigmentation is limited to one or a few areas of your body. vitiligo often first appears between the ages of 20 and 30. eyelashes. arms. eyebrows or beard * Loss of color in the tissues that line the inside of your mouth (mucous membranes) * Loss or change in color of the inner layer of your eye (retina) Although any part of your body may be affected by vitiligo. Visit Vitiligo Corner Visit Vitiligo Cover Lotion Page 6 .Vitiligo Corner 2010 Vitiligo Symptoms The main sign of vitiligo is pigment loss that produces milky-white patches (depigmentation) on your skin.

once achieved. But there is always the fear that the white patches may return and spread more widely than before. education. fear. personality. Be prepared with a few simple explanatory phrases. vitiligo need not prevent you from doing what you want in life. the country you live in. They are not functioning properly or are missing from my skin and that causes these white patches which can burn easily in the sun if I do not protect my skin. However. Most people after they have been diagnosed experience a range of feelings and emotions including shock. It is not surprising that people stare at the sight of vitiligo because it looks strange and they do not know what it is. “It is vitiligo. You are entitled to choose how much or how little you discuss it. Although support from friends and family is essential you may find a course of counseling helpful. Humor is another way of dealing with rude or insensitive remarks. Family background and upbringing. Try to have a few funny remarks up your sleeve to use when the occasion arises. Visit Vitiligo Corner Visit Vitiligo Cover Lotion Page 7 . A lot of people never get to the last stage and many can become overwhelmed by low self-esteem and lack of confidence. There are. Explaining what it is can help to dispel their fears but you are not obliged to talk about it. especially with strangers. should make it easier for you to deal with intrusive staring and rude remarks and go out in public without feeling ashamed or ugly. Focusing on your good points and building up your self-esteem will help to put vitiligo in perspective. Some people with vitiligo never really fulfill their potential and many children are teased and bullied with some reported cases of underachievement at school. anger. It is not life-threatening and it is not catching”. treatments that can improve the condition. denial. of course. and sometimes this improvement can last for many years. The color of your skin is not the only thing that makes you who you are. cultural and religious beliefs. anxiety. They may recoil because they are afraid of catching it. guilt. depression and finally acceptance. Not many people can boost their confidence without help. a condition that affects the pigment cells in my skin. isolation.Vitiligo Corner 2010 Life with Vitiligo A diagnosis of vitiligo can seem like a life sentence as the unpredictable course of the disease means no-one can be sure how it will progress and until a cure is found people with vitiligo must learn to live with it. Self-confidence. are more important in defining you as a person. once you realize it does not have to take over your life and is only part of who you are. Having vitiligo is not a tragedy although the loss of your skin color can also appear to threaten your racial identity if you have dark brown or black skin.

Maybe it’s not even lonely that you feel. it’s page after page of messages written as if the Universe was telling you little reminders of the absolute power you have over your life. issues that I have to deal with creep into my thoughts and I feel scared because. then my life change when I got a job teaching at a local college. It is from “the universe”. I felt this way often when I worked from home. ” Visit Vitiligo Corner Visit Vitiligo Cover Lotion Page 8 . Here are some examples: “Just how much time do you spend thinking big? Good. Because that’s exactly how much of “It” you’re going to get. while at the bookstore.Vitiligo Corner 2010 Vitiligo Corner Posts 2010 Does vitiligo make you feel lonely? 7 January 2010 No Comment It’s very easy to feel alone in the world even if you’re surrounded by family and friends. or just your life in general. It was as if a whole new world opened up to me and happiness flooded into my life. very good. I came across a book by Mike Dooley called. What a coincidence. and began going out with them at the weekend. Now. made friends. The only time I would be around other people was when I’d get out to run errands. “Notes from the Universe”. each morning I awake to the alarm on my mobile alerting me to read an incoming email. But. My choice of work and my lifestyle isolated me from the outside world going on all around me. separateness from people. I feel as if I have to handle them on my own. this doesn’t mean that I never feel isolated. just before I fall asleep. Basically. A few months ago. I do. I went to the author’s website and signed up for a daily note from the universe to be delivered to me each morning. but rather. Then. It could be the vitiligo that makes you feel this way. Late at night.

Vitiligo Corner 2010 “When suddenly the unexpected happens. mean it The Universe” “What people rarely give themselves credit for is that their giving continues giving. I feel a sense of peacefulness and serenity. Which is not to suggest that you should look back now. it’s always me… just getting everything ready for the time of your life. The Universe” Even after re-reading them to place in this post. Note to self: read these notes at night before bed. forever and ever and ever. Love you. too! Visit Vitiligo Corner Visit Vitiligo Cover Lotion Page 9 . rarely do you know how good you have it. even after they’ve forgotten giving. and even when they didn’t know they were giving. The Universe” “When driving down the road of life. but to remind you that where you are today is more awesome and amazing than you probably realize. until you see it in the rear-view mirror. nathalie. 10-4. At least I’m keeping score.

this highly intense conference – the Faculty of which is made up by the most eminent experts in the field – sets itself the goal of becoming an ideal occasion for an innovative and in-depth analysis of vitiligo. In view of the fact that these last ten years have witnessed a growing interest for research and an improved understanding of the mechanisms regulating the disease. often found within the depths of Internet. Visit Vitiligo Corner Visit Vitiligo Cover Lotion Page 10 . using the words of its Founder and President. “the San Raffaele complex focuses exclusively on every aspect of man: a blend of soma. of its genetic susceptibility and of the role played by autoimmunity. 2010 at the San Raffaele Scientific Institute in Milano. Don Luigi Maria Verzé.Vitiligo Corner 2010 First vitiligo world congress 2010 9 January 2010 10 Comments Today I came across a very exciting announcement. and that there are many. it’s an indication that our voices are being heard. with a major impact on both patients and their families. of being classified as a disease by the WHO (World Health Organisation) and of being one of the most psychologically devastating chronic skin diseases. Why a congress dedicated solely to vitiligo? Because in spite of not being a rare disease. leaving them vulnerable to therapies not proven effective. vitiligo is still today underrated and underestimated. intellect and spirit as far as duration and quality are concerned”. who trivialize the condition or deceive patients’ expectations. Why at the San Raffaele Scientific Institute? Because. many people out there who truly want to help find a cure for vitiligo and find a way to better our lives while they work to find that cure. Dear Friends. To most people in the world it may seem like just another convention. but for us with vitiligo. Still today there are dermatologists who minimize the impact of the disease. as well as because clinical and basic research are core activities of the Institute. It is a great honour and pleasure for me to chair the FIRST VITILIGO WORLD CONGRESS to be held on September 23-24.

photobiology and psychology. Old and new therapeutic approaches for vitiligo are going to be a major issue for debate. where are we now? Interaction among patients. will be dedicated to patients: “Vitiligo. Santo Raffaele Mercuri Visit Vitiligo Corner Visit Vitiligo Cover Lotion Page 11 . Prof. touching on such different research areas as genetics. endocrinology. Saturday. clinicians and scientists”.Vitiligo Corner 2010 The Congress is going to focus on recent developments in our understanding of the disease. With the hope that each one of You would make his own contribution to this Congress I send you my best regards. immunology. September 25. Goal of this event is to allow patients to play an active role in the field of research and to provide them with more information on existing therapies.

helping them to cope with the disease and its disfiguring unpredictable skin changes. The First Vitiligo World Congress is a good opportunity to open new communication channels: patients will have the chance to work in partnership with investigators. clinicians and healthcare professionals. representing the interest of those affected by vitiligo. a patient-driven. 2010 General Information This meeting is realised in co-operation with ARIV (Associazione Italiana Ricerca e Informazione per la Vitiligine). Moreover. Congress Venue San Raffaele Congress Centre Via Olgettina 58 – 20132 Milano Italy Organising Secretariat San Raffaele Congress Centre Via Olgettina 58 – 20132 Milano – Italy Phone +39 02 2643 3725 Visit Vitiligo Corner Visit Vitiligo Cover Lotion Page 12 . interacting with members of the international vitiligo scientific community. non-profit organisation based in Italy. patients will have the opportunity to assume an active role in participating and encouraging present and future research. CLINICIANS AND SCIENTISTS Milano.Vitiligo Corner 2010 VITILIGO 2010: WHERE ARE WE NOW? INTERACTION AMONG PATIENTS. Its aim is to improve the quality of life of patients and family. September 25th.

# 12 April 2010 at 4:40 am Visit Vitiligo Corner Visit Vitiligo Cover Lotion Page 13 . It is the only vitiligo directory. did it work? I have a few spots on the back of my hand and considering to cover it with tattoo? Any advice based on your experience? # 17 March 2010 at 5:13 pm Unknown said: I would like to thank you for your care to finding a cure for vitiligo. Vitiligo Websites. we need to get the word out so the public will be educated and aware of this skin disorder. The public looks at me like I’m a monster. My partner has been struggling with the disorder for 4yrs and it has not been easy.. I tried every thing form make up to tanning beds and it just looks worst. Vitiligo Treatments. Help us we need a cure. Please help our loved by finding a cure# 17 March 2010 at 5:19 pm Sam said: Submit vitiligo resources (Vitiligo Products. A few years ago i got tatoos over my feet just so i could wear sandals and feel comfortable.# 17 February 2010 at 8:39 am susana said: i have vitiligo for 25 yrs. Its been really difficult for me specially because i live by the beach. Vitiligo Support Groups) at Vitiligo.When you tattooed you feet vitiligo. im just to embarrased.Vitiligo Corner 2010 10 Comments william crump said: I have vitilligo for 3yrs. since i was 8 yrs old. I have never worn shorts or even a dress. we need help!# 16 March 2010 at 6:51 pm Susana said: A quick question. Vitiligo Clinics. and I hate it.

maybe get lucky this time!# 24 April 2010 at 9:11 am Kaushik said: i have vertilogo for past 15 years and its spreading…. As I was a kid. Hopefully the pigment will last.. Hope this helps!# 26 May 2010 at 6:00 pm Visit Vitiligo Corner Visit Vitiligo Cover Lotion Page 14 . Thats interesting. can be helped and treated!# 14 April 2010 at 8:59 am joel said: ei nice news! the 1st Congress of vitiligo thats good. Basially its due to the mutation on cromozome 17# 26 May 2010 at 3:40 am RA said: Hi Kaushik.. and the big spots on my knees have disappeared since a couple of years. but I’m now having more and more little spots all over my arms and legs… I hope there will be more and more interest.i am in love with one girl but could not express my feelings because i am worried she will reject me for this desease plz suggest some thing so that one morning i woke up and see myself free from vertilogo. so people.Vitiligo Corner 2010 kaelen said: Hi! I’m glad that there’s more and more attention drawn to this disease. is a combination of vitamins and nb uvb and sometimes natural sunlight. because of my brother who enjoyed calling me big ugly panda or cow… My knees and eyelids were the worst.. I’m now 26yrs old. I didn’t know vitiligo had something to do with a chromosome mutilation. and most importantly children with vitiligo. My face has repigmented 100% and the other areas are starting to freckle in. this was a big issue for me. I myself have vitiligo since I’m a little kid. The treatment that has worked for most people. we just got to be strongs… I will start one new treatment. including me. There are several treatments that work for people but there is no magical cure. I have vitiligo.

I found a great set of tools to help in this quest while listening to a podcast in which self forgiveness was the topic. Did your vitiligo manifest after a stressful event. Forgiveness. So why do I keep a grudge against myself? Why can’t 40 year-old Nathalie forgive 16 yearold Nathalie for not sticking up for herself? After all. It’s time to forgive myself. Nothing illegal. you’ll at least lead a happier life Visit Vitiligo Corner Visit Vitiligo Cover Lotion Page 15 . It’s much simpler to forgive someone else than it is to forgive ourselves. depending on the individual. what I knew about life at 16. and i still hold a bit of shame and anger. or is there an emotional connection? Perhaps it is any of the 3. The guest was Carl Tipping and he talked about his workshop and discussed methods to forgive. You know. the old “why didn’t I say this” or “why didn’t I just do that”. self punishment. mind you. Let’s look at the emotional connection. Hey.Vitiligo Corner 2010 Can forgiveness cure vitiligo? 17 January 2010 No one knows the exact cause of vitiligo. but is the catalyst simply the predisposition. What I liked most about his methods is that you don’t have to conjure up and relive every stressful event that is still bothering you. This one is pretty easy to determine whether or not it applies to you. there are many situations that have occurred throughout my life that I need to forgive myself for how i responded to the situation. it’s just that in many situations I did not stand up for myself. I don’t hold grudges towards the people involved in situations that still anger me. maybe the cure for your vitiligo lies in simply forgiving either yourself or others for events that caused you stress. and there are many theories as to why it manifests. or a combination. and even if it doesn’t cure your vitiligo. either physical or emotional? Or perhaps you led an emotionally stressful life and then one day you began noticing the white patches? If you answered yes to either of those. We can all agree that who ever gets vitiligo has a particular gene which predisposes them to it. a chemical reaction. Here is a link to his site where you can find all of the tools. Personally. is nothing compared to what I know now.

I believe an accumulation of anxiety and regret can lead to an unhealthy state mentally and physically in anyone.Vitiligo Corner 2010 2 Comments anon said: Hi Nathalie. Stay positive Nathalie!# 19 January 2010 at 12:48 am Visit Vitiligo Corner Visit Vitiligo Cover Lotion Page 16 . we need to constantly remind ourselves to focus on the silver lining amidst these often gloomy clouds of our past and that await in our future. Since Vitiligo may be sensitive to stressful situations. I agree with your stance.

” wrote I. Esfandiarpour and colleagues. “Sixty-eight patients with vitiligo enrolled in this randomized. Atlanta: Mar 27. placebo-controlled study. 2009.05%). Esfandiarpour and colleagues in the area of vitiligo. double-blind. No significant side effects except self-limited erythema and pruritus were observed. The patients were randomized into two groups and treated with NB-UVB plus either pimecrolimus or placebo for 3 months. Tri-weekly radiation was started at 280 mj/cm2. After 12weeks of treatment. Drug Week. There was no statistically significant difference in the repigmentation rate between the two groups on other body areas. At baseline and 6 and 12weeks after commencement of therapy. Protopic). hands) is limited. 1223 Visit Vitiligo Corner Visit Vitiligo Cover Lotion Page 17 . pg.Vitiligo Corner 2010 Vitiligo treatments: nbUVB and pimecrolimus 24 January 2010 No Comment A study performed by researchers in Iran concluded that nbUVB vitiligo treatments are more successful when associated with topical immunomodulators (Elidel.3 vs 25. repigmentation of the facial lesions was higher in patients treated with combined pimecrolimus and NB-UVB compared with the placebo plus NB-UVB group (64. SOURCE Study results from I. vitiliginous patches were measured. elbows. Their findings tell us that a vitiligo treatment should be dependant on the body area where the white patches are located.1%) (p 0. with 15% increments for each subsequent treatment until erythema was reported or a maximum of 800 mj/cm was achieved. While tacrolimus may be used effectively on the face (with or without UVB) it’s efficiency in other areas (feet. Fifty patients completed the 3month study.

He explained that in this technique melanocyte cells were taken from an intact area and injected after the epidermis layer was separated. a dermatologist with the research team. has told IRIB that the new technique removes vitiligo lesions in less than 6 months. The researcher said two third of vitiligo patients are cured using available treatments while the new method is believed to be promising in the remnant one third. much shorter than other available methods. Visit Vitiligo Corner Visit Vitiligo Cover Lotion Page 18 . In this technique. there is no need to abrade the skin or expose the patient to ultra violet radiation.Vitiligo Corner 2010 Iran ‘revolutionizes vitiligo treatment’ 15 February 2010 9 Comments Iranian Scientists with the Royan Research Center have successfully treated a skin disease using patients’ own pigment producing cells. Saeed Shafiyan.

Now there is something extraordinary in Iran…can we believe it? I wrote IN AUGUST 2009 to the french Ministry of Health but she never ansmered to my proposal to recognise this “disease” such as an handicap and to benefit of the special advantages for companies who hire enabled people as it is realized in Portugal I believe. I have tried to est chickpeas and some very feew spots overcome.Vitiligo Corner 2010 9 Comments RA said: This is exciting! I wonder if it will be available in Canada any time soon…# 15 February 2010 at 1:39 pm alex said: Great news Nathalie!!!!!!!!!!!!!!# 16 February 2010 at 7:16 am Atul said: Really Great! When same will be available in other countries like India…# 17 February 2010 at 3:21 am healvit said: It’s been 2 years since they claimed they’ve found a ‘cure’. I don’t know how much longer we gonna wait…I hope it’s not another useless speculation like the ‘chickpea’ and ‘black pepper’ and so no ‘cure’.# 5 March 2010 at 8:08 am Visit Vitiligo Corner Visit Vitiligo Cover Lotion Page 19 . I don’t know how much longer we gonna wait…I hope it’s not another useless speculation like the ‘chickpea’ and ‘black pepper’ and so on ‘cure’.# 17 February 2010 at 8:11 am christophe france said: Last time there was a cure wiht black chickpeas in india.# 17 February 2010 at 8:11 am healvit said: It’s been 2 years since they claimed they’ve found a ‘cure’.

Rajeev# 13 May 2010 at 10:07 pm Bruce said: It’s been 2 years since they claimed they’ve found a ‘cure’. I don’t know how much longer we gonna wait…I hope it’s not another useless speculation like the ‘chickpea’ and ‘black pepper’ and so no ‘cure’.Vitiligo Corner 2010 kelm said: This is not new. Is this available in India? and who are the contacts in Iran and what is the cost of the procedure. this has been done in Sweden years ago.# 8 March 2010 at 12:52 am Rajeev said: Hi. Regards. # 19 May 2010 at 9:20 am Visit Vitiligo Corner Visit Vitiligo Cover Lotion Page 20 . Please revert back if there is any moderator of the article also.

Abigail Rose. who lives in Hillside Road. you can text Abigail Rose to 84205 or telephone 0901 656 153009 then enter 09. aged 14.Vitiligo Corner 2010 Teen model’s vitiligo campaign 23 February 2010 2 Comments A BEAUTY pageant finalist from Harpenden is using her newfound fame to raise awareness about the chronic skin disorder she suffers from. who recently addressed the Vitiligo Society’s Medicine and Me symposium at the Royal Society of Medicine.hertsad. is greatly involved with the Vitiligo Society and manager of the charity Jennifer Viles said that she was pleased to have Abigail on board.” Abigail currently has just under 150 public votes and to help her get through to the live finals in August. entered the pageant to raise awareness about vitiligo.” She added: “It’s very nerve-wracking being in the Teen Princess Pageant but all my friends and family are being very supportive and I enjoyed the professional photo shoot. who is a keen supporter of the Vitiligo Society. she is now in the final heats of the competition. “We are very proud to support Abigail to reach the final of the Teen Princess Beauty Pageant. said that the pageant was the perfect opportunity to spread the word: “What better way to give vitiligo publicity than to be in a competition like this? One of the biggest parts of dealing with the condition is the feeling of being the only one and I can help people with that.co.” Abigail.aspx?brand=HADOnline&category=News&tBrand=HertsCambsOnline&tCategory=newslatestHAD&itemid=WEED25%20Jan %202010%2012%3A15%3A14%3A897 Visit Vitiligo Corner Visit Vitiligo Cover Lotion Page 21 .uk/content/herts/news/story. By supporting Abi we will all be showing the world that having vitiligo stops noone from being successful and beautiful. published 25 January 2010 http://www. “Hopefully I will get lots of votes from the public and I will make it through to the final. Abigail. of Hillside Road. was talent scouted for the Teen Princess UK pageant at the Clothes Show in Birmingham last December and after having successfully got through the first round. a condition she has suffered from for nearly 10 years which causes the skin and sometimes the hair to turn white in patches. St George’s Secondary School pupil Abigail.

I have three children. But my illness will not let me be happy.# 23 February 2010 at 6:58 pm Barno said: Please help me. I suffer from Vitiligo and would like updates. # 15 April 2010 at 5:09 am Visit Vitiligo Corner Visit Vitiligo Cover Lotion Page 22 . as I recover from the disease. I have long been sick vitiligo. Please advise.Vitiligo Corner 2010 2 Comments Olga Medina said: God bless you having this event. I am very happy. Thank you.

please join us on facebook.louis. louis vitiligo support group meet-up 27 February 2010 One Comment If you live in or near st. 2010. missouri. and we would love for you to join us.Vitiligo Corner 2010 st. we are planning a meet-up in april. For the lastest information about our get-together. Visit Vitiligo Corner Visit Vitiligo Cover Lotion Page 23 .

lighter dinner jackets seem to emphasize the vitiligo condition…Best Regards!# 1 May 2010 at 8:34 am Visit Vitiligo Corner Visit Vitiligo Cover Lotion Page 24 . Play several rounds of golf during the week and use tanning lotions to blend the white blotches on my face. I have a naturally dark color to my skin and noticed this condition initially when I was in the military in Heidelberg. During the summer. Germany in the early fifties. My wife kept me stocked with Revlon Colorstay and I continue to repurchase as needed.Vitiligo Corner 2010 One Comment Lloyd Jacobs said: I am very interested in joining the STL Vitiligo Group. I am an active 79 year old widowed man who lives in Chesterfield.

“This surgery offers hope to vitiligo patients. “The results achieved in our study were of obvious significance to our patients. Henry Ford researchers followed 23 patients for up to six months after surgery and found that the treated area regained on average 52 percent of its natural skin color. a senior staff physician in Henry Ford’s Department of Dermatology and the study’s senior author and principal investigator.Vitiligo Corner 2010 Skin transplant offers hope for vitiligo 12 March 2010 6 Comments Henry Ford News Skin Transplant Offers New Hope to Vitiligo Patients March 9.874.org 313. M. the treated area regained on average 74 percent of its natural skin color. Visit Vitiligo Corner Visit Vitiligo Cover Lotion Page 25 .flickr.” The study will be presented Tuesday.com/photos/hfwbh/ DETROIT – In the first study of its kind in the United States. March 9 at the 68th annual American Academy of Dermatology meeting in Miami. 2010 CONTACT: David Olejarz dolejar1@hfhs. It is performed under local anesthesia.” says Iltefat Hamzavi. The surgery involves using skin cells taken from normally-pigmented areas of the body and transferring them to the damaged area of skin. Henry Ford Hospital showed that skin transplant surgery is safe and effective for treating vitiligo. In eight patients with a specific type of vitiligo.4094 Skin Transplant Offers New Hope to Vitiligo Patients Before and After Photos available at www.D.

Asia and Middle East. M. 23 were followed for up to six months after surgery. Hamzavi says. This mixture then is applied to the treatment area and covered with a specially developed adhesive biologic dressing. Of the 32 surgery patients..” Dr. and is more noticeable in people with darker skin. In Henry Ford’s study. and is performed in Europe. It affects about 1 in every 200 people in the United States. The ethnicity of patients was Caucasian. Visit Vitiligo Corner Visit Vitiligo Cover Lotion Page 26 . A procedure lasted 30 minutes to two hours and patients returned home the same day. are harvested from an area of healthy skin and separated to make a skin cell mixture. melanocyte cells. which produce pigment in the skin. vitiligo can be treated and managed with light therapy. Vitiligo develops when cells called melanocytes are killed by the body’s immune system. African American and Hispanic. Dr. “Patients of color and those with vitiligo on one side of the body and in one area of the body may benefit most from this procedure. During MKTP. Eighteen patients received one treatment. South Asian. While there is no cure. 14 female) underwent surgery and ranged in age from 18 to 60. He says for some patients the surgery is more effective than standard treatments like light therapy and topical medications.D. of the National Vitiligo Center in Saudi Arabia. causing the area of skin to turn white because the cells no longer make pigment. four patients received two and one patient received three.Vitiligo Corner 2010 While the initial results are preliminary and the procedure is still investigational. Henry Ford is the first to perform MKTP in North America. creams and topical medications. hair and eyes. A total of 40 MKTP procedures were performed and researchers analyzed the outcomes of 29 of them. Vitiligo is a skin disease that causes the skin to lose color and develop white patches that vary in size and location. The surgery is known as melanocyte-keratinocyte transplantation or MKTP. Hamzavi says Henry Ford hopes to offer the surgery as part of its treatment portfolio this fall. It was performed at Henry Ford using the same technique developed by MKTP pioneer Sanjeev Mulekar. 32 patients (18 male.

legs. Riyadh. Visit Vitiligo Corner Visit Vitiligo Cover Lotion Page 27 . The average size of the treated area during each procedure covered an area of 46 cm2. Saudi Arabia. face and stomach. or roughly the size of a credit card. feet. arms.Vitiligo Corner 2010 Treated areas included the hands. and funded by the Shahani Foundation based in Michigan. The study was collaboration with the National Center for Vitiligo.

S. to do so but never every get any little progress by doing Visit Vitiligo Corner Visit Vitiligo Cover Lotion Page 28 . Not anymore. I have only had Vitiligo for one year. I have never get any advice by derm. I’m not scared anymore.this made me feel the same way u did. 3 days in a week. everyday it seems that I read about a new advancement in treating this disease. finally my mind is at peace a little and it doesnt feel like im having a heart attack anymore haha. Mary# 12 March 2010 at 6:33 pm jake said: Its coming Mary … I can smell it i never got excited about treatments till now. I’m so thankful to people like Natalie and others who take the time everyday to find this information for all of us. I..Vitiligo Corner 2010 6 Comments Mary said: wow wow wow…this is very exciting for all of us!! We are finally seeing light at the end of the tunnel. The best I found is psorolen pills and sun bath but need to be done for at least 2-4 months and carefully without exceeding time more than 1 minute each day. So I don’t know what to think with the rate of success but seemed to me again like primary school. narrow band did nothing to me just emptied my pocket and wasted time. I wake up with hope now. I recently consider IV Glutathione what will shade the difference by whitening the rest of my skin complexion. to excited for words# 13 March 2010 at 3:19 am Sermin said: One time completely and 2 times at least %90-95 in my areas I could manage the regain my color back they all came back once I gave up sun bath and psorolen pills. This is so great for those of us that live in the U. It seems more and more countries are advanceing themselves in performing this procedure. I used to get up in the morning an feel scared about my future and wonder what I will look like in 10 years. It relieves some of the stress that we all carry and that may make our Vitiligo spread.m so grateful for this site. and Canada... I don’t mean that is nothing but we could get around %75 with PUVA. God Bless.

It is indeed a good progress. it is in India too. # 16 April 2010 at 5:38 am Tina said: I have had vitiligo for 4 years. it was very expensive but the results are worth it….# 13 March 2010 at 10:04 am Bamsegutt said: This treatment is not new it has been in Sweden for many years and some other countries has catch up .. the pigment comes gradually after some months. It hasn’t really bothered me and I’ve done nothing about it. I have a couple of questions: Is this ok to use on face? Do you have any recommendations of where to buy the wand? Thanks! Tina# 22 April 2010 at 10:54 am Charlotte Wright said: my dad recently got a Hair Transplant. But now I’m concerned because it is starting to show up on my face.Vitiligo Corner 2010 what they wanted me to do maybe only because they can not empathize every individuals situation and can not make sure how serious we may apply sun bath with extreme care so. First off all your vitiligo must be stabile other wise it is easy that it will be attacked again. I’m looking into buying a untraviolet UVB handheld wand.# 19 May 2010 at 4:37 am Visit Vitiligo Corner Visit Vitiligo Cover Lotion Page 29 . even if the transplantation takes some hours .

promising vitiligo concealing method 21 April 2010 On April 13. It is a light liquidized application which is applied on to the epidermis (top layer of skin). Her vitiligo began when she was 34 after she gave birth to her son Timothy. but it only lasts a few days. and it won’t rub off on clothing or linen. Microskin is not a cream. Dr Roy Geronemus treated Tracy’s vitiligo with a new procedure called Microskin which is like a second skin to match her own. The special guest with vitiligo was Tracy Edwards. it won’t come off in the shower or while swimming. It doesn’t require makeup. 2010. Microskin is suitable for all genders and skin types. the Dr.Vitiligo Corner 2010 Dr. What is Microskin? Microskin is a simulated second skin which is formulated individually to color correct skin conditions.Oz show. flexible. Once applied. She explained that every time she looks in the mirror she feels like a monster and that she is ashamed to show her face because people stare at her whenever she goes out. It’s waterproof and allows your skin to breathe. Visit Vitiligo Corner Visit Vitiligo Cover Lotion Page 30 . and doesn’t have the makeup appearance like other camouflage products. a 47 years old woman. Microskin is durable. Micro Skin of New York donated one year of the Micro Skin product to Tracy for one year. Oz did a segment about a new method to conceal vitiligo called Microskin.

acid blocking medications (often used for symptoms that are actually due to a lack of HCL). A partial list includes: regular use of non steroidal anti-inflammatory drugs (NSAIDs). autoimmune disorders. a B12 deficiency sets in and can result in pernicious anemia. just to name a few. By taking antacids. And while I hear many ideas on the potential causes of vitiligo. hypothyroidism. it’s just low stomach acid. but it also kills many organisms and helps to keep the stomach sterile. pylori. It is also important to remember that if you don’t make enough HCL to disinfect and kill off bacterial and parasites in your food. vitiligo connection? 3 May 2010 6 Comments A few people have brought up a theory that Hypochlorhydria may be what triggers the vitiligo gene to turn on. Stress can also impair HCL production as well as alcohol consumption and food allergens. Nigel. the parietal cells also manufacture “intrinsic factor” which makes the absorption of B12 possible. doesn’t it? But it’s not. What is hi-po-klor-hi-dree-uh? Basically. HCL is not only necessary for proper digestion (it begins the breakdown of protein) and thus nutrient absorption. Without adequate intrinsic factor. Visit Vitiligo Corner Visit Vitiligo Cover Lotion Page 31 . are the parietal cells. you will have less stomach acid being secreted setting you up for infection and malabsorption. that sounds harmless enough. For the next few days I am going to do a series of posts about the online research i’ll be conducting on hypochlorhydria. The cells that produce stomach acid. all of which are needed for HCL production. (Plummer. zinc. This chronic bacterial pathogen in humans is so prevalent that 50% of 50 year olds are infected with H. It is commonly assumed that the decline in stomach acid production observed through later adult life is normal and a very common consequence of the aging process. a common cause of ulcers. Several things can affect the ability of the parietal cells to produce hydrochloric acid. you may also be more prone to gut infections and small intestinal bacterial overgrowth and malabsorption. In addition to HCL. Most people don’t have too much stomach acid as you would think from watching the pharmaceutical commercials on TV. you may be more susceptible to infection by Helicobacter pylori. nutritional deficiencies such an histidine (an amino acid). shows that this is incorrect. Dr. however. this one fits many issues that we’ve already linked to it: b12 deficiency. low folic acid. Townsend Letter. Well. July 2004. Recent evidence.Vitiligo Corner 2010 Hypochlorhydria. Once the stomach acid is low. also known as hydrochloric acid or HCL. and vitamin B1 (thiamine).

In all cases. and Biotics Research Labs has Hydrozyme. If a capsule contains 500 mg. you will want to take HCL as Betaine Hydrochloride. Visit Vitiligo Corner Visit Vitiligo Cover Lotion Page 32 . then an individual should start with one capsule per meal and then build up to 3 capsules per meal. I have two that I use in my clinic—Premier Research Labs has 2 products to be used together. of Betaine Hydrochloride. Sometimes you may need to take even more than 3 if you are extremely low in HCL. It is best to take these products in the middle of each meal. Quantum HCL Activator with Quantum Betaine HCL. it is prudent to begin supplementation in steadily increasing levels.Vitiligo Corner 2010 A partial list of symptoms associated with low stomach acid includes the following: Gas shortly after eating Allergies Autoimmune disorders Thyroid disorders Diabetes Mellitus Gallbladder problems Asthma Vitiligo Acne rosacea Chronic Hepatitis Indigestion ½ to 1 hour after eating that may last 3-4 hours Constipation Belching Diarrhea Bloating Weak Adrenals Rheumatic Arthritis Hypoglycemia Dry Skin Chronic Fatigue Bad Breath Weak Nails Poor night vision Lupus erythematosis Loss of taste for protein foods If you have symptoms of low stomach acid. You can increase until you get a burning sensation and then you know you need to back down but it is a good idea to have some Alka Seltzer on hand. Make sure you consult your nutritionally oriented physician prior to supplementing with HCL. There are several good brands of Betaine HCL on the market.

For all problems dealing with the gut. pylori bores in. wormwood and ginger.com/p/articles/mi_m0ISW/is_252/ai_n6160495/ Visit Vitiligo Corner Visit Vitiligo Cover Lotion Page 33 . In addition. pylori are: Metagenics’ Zenlori. particularly oregano. Without proper digestion. Pharmax developed a product Pyloricin. HCL is one of the most difficult chemicals for the body to make and. sets us up for multiple problems such as an inability to break down our food properly for absorption. most digestive dysfunctions start in the stomach with decreased HCL. in this product.Vitiligo Corner 2010 If your doctor does lab work and finds you have an infection of H. pylori. pylori at very low concentrations and that it was effective against at least 3 different strains of H. In conclusion. the loss of which. http://findarticles. Other companies that produce therapies for H. containing the same mixture of oils. clove. Studies published in the New England Journal of Medicine have shown that mastic gum inhibits H. I recommend taking probiotics such as Bifido bacteria and Acidophilis bacteria. pylori. Allergy Research with Mastica. it produces a milky emulsion enabling the antimicrobials to effectively disperse and penetrate the mucous layer and attack the surface and deep layers where H. (N Engl J Med. 339 (26): 1946 Dec 1998. and Biotics Research Labs with Bio-HPF. the University of Wolverhampton in Great Britain has found that 3 different strains of H. You can check with your local health food store for a suitable brand. Following the release of this data. the oil mixture is emulsified so that once it is in the stomach. pylori were highly sensitive to some mixtures of essential oils. we cannot obtain the nutrients from our food which can then make us more prone to multiple health problems and disease.

where the doctor firmly believed that low stomach acid was the cause of Vitiligo. I have Acid-Reflux as well and I am not sure if Hypochlorhydria has some connection to that. t is easy and relatively inexpensive with the greatest expense being some burn. He himself. Another thing is that I have really bad breath at certain times. I believe it’s from my gut. My cousin who has vitiligo also suffers from the same ailment. Certainly this therapy is worth a try. I’m very strict with dental care. Let us know if we can check with some research team or any Doctor. Regards# 4 May 2010 at 12:27 pm Mary said: It’s so strange. That’s always at least half the battle. had vitiligo and was able to supposedly “cure” himself of it. Thank you for going to the time and trouble. which will increase your stomach acid levels. There was a study done in the early 1940’s I believe. He recommended that anyone with Vitiligo take 1 tsp of cider vinegar per day. not all the time. I was just reading about this online the other day. it’s not from my mouth.# 4 May 2010 at 7:37 am VEN said: Natalie. Does anyone else out there with Vitiligo have the same issue?# 5 May 2010 at 8:25 pm ishara said: hi there Visit Vitiligo Corner Visit Vitiligo Cover Lotion Page 34 .Vitiligo Corner 2010 Comments cheryl planert said: Great article and I appreciate you having done the work of finding good products. a sign to cut back.

as I have been a long suffering with many of the above symptoms – regardless of what i eat – i have gas.# 7 May 2010 at 9:18 am Mary said: Does anyone have any concerns about “Elidel”and the FDA box warning? Does anyone have any data relating to the cancer risk?# 14 May 2010 at 8:35 am Visit Vitiligo Corner Visit Vitiligo Cover Lotion Page 35 . I am on meds (topical application with daily exposure. bloating – i have allergies and asthma – my mom is completely depigmented and in addition to eh above has diabetes and hypothyroidism. This article is so helpful..Vitiligo Corner 2010 My vitiligo has worsened recently and i have been trying to find ways of curbing the spread. night cream and daily tablets). The new spot on my face has repignmented – and I am also now taking kalawalla – started a few days ago.

The study was supported by grants from the US National Institutes of Health and a grant from the Anna and John Sie Foundation. The study was published in the peerreviewed New England Journal of Medicine.813 without the condition. along with international researchers. Visit Vitiligo Corner Visit Vitiligo Cover Lotion Page 36 . such as malignant melanoma. according to BBC News. The study looked at 1. was previously assumed to increase the risk of serious skin cancers. which reported both the strengths and limitations of the study and correctly placed little emphasis on suggestions that the finding could quickly lead to new treatments. and even a reduced risk of melanoma does not mean that there is no risk. but at this stage it is too soon to say if these findings have major implications for melanoma risk in people with vitiligo.Vitiligo Corner 2010 Pigment disease ‘reduces cancer risk’ No Comment Published Date: 23 April 2010 People with vitiligo “may have natural protection against skin cancer”. The researchers identified several genetic variations associated with an increased risk of vitiligo. Where did the story come from? This study was carried out by Dr Ying Jin and colleagues from the Human Medical Genetics Program at the University of Colorado School of Medicine. which causes pale skin patches due to a loss of pigment. Two of these variations were also associated with a reduced risk of melanoma. The most important finding of this study was the identification of genetic variations associated with vitiligo. While vitiligo is thought to be partly triggered by environmental factors. The condition involves patchy loss of colour in the skin and hair. the condition is also known to be partially caused by genetics. such type 1 diabetes and rheumatoid arthritis. The suggestion of a link with melanoma will no doubt prompt further research. What kind of research was this?This was a genome-wide association study in which the researchers wanted to identify the areas of the genetic code (called susceptibility loci) associated with generalised vitiligo. some of whom were based at universities in Sheffield and London. The condition. caused by the body attacking its own pigment-producing cells (melanocytes). and several others were located in regions containing genes known (or thought) to play a role in other similar immune conditions.514 people with vitiligo and 2. This research was covered by BBC News. The researchers themselves warn that people with vitiligo should still be careful in the sun as they can sunburn quickly.

These are different sets of samples and are typically used in this type of study to test the reliability of specific SNP associations found in the first analysis. focusing on these SNPs in two independent “replication sets”. What did the research involve? The researchers took samples of DNA from 1. The results were then confirmed by comparing them to a second set of samples. These procedures were described extensively in supplementary material.106 controls. The research was well described and conducted. Visit Vitiligo Corner Visit Vitiligo Cover Lotion Page 37 . such as DNA purification. The genotype data from these patients were compared with the genetic sequences of 2. The first replication set included 677 unrelated patients with generalised vitiligo and 1.146 genetic sites assessed. The use of replication sets increases the reliability of the findings.813 healthy people.146 variants or single-nucleotide polymorphisms [SNPs]) across large areas of the genetic code in 1. All those tested were of European white ancestry. they repeated the analysis.514 patients from North America and the United Kingdom who met the clinical criteria for the diagnosis of generalised vitiligo. Also important in these types of study are the quality-control procedures used to ensure that processes.813 control participants drawn from datasets stored in a US database. After the researchers had assessed which SNPs were associated with vitiligo. The second replication set featured a familybased cohort of 183 samples from families where parents and offspring were affected by vitiligo and 332 samples from families with two or more affected family members and their unaffected relatives as controls.514 patients with generalised vitiligo. This suggests that these diseases have shared genetic components.Vitiligo Corner 2010 The researchers already had an idea of which sections of DNA to examine as previous studies have suggested several potential loci. The research involved genotyping. the researchers looked at single-letter variations (579. The researchers assessed how common the different variants (alleles) were at each of the 579. patients with generalised vitiligo often have other autoimmune diseases. such as autoimmune thyroid disease. rheumatoid arthritis. looking to see whether any variants were more common in people with vitiligo than in those without it. They also assessed the degree of association (how much more common the variant was) and the probability that any associations could have arisen by chance. psoriasis and adult-onset type 1 diabetes. This is a process of scanning the genetic code found in sections of DNA. In addition. are carried out correctly. These sample sets were tested for the presence of 50 SNPs in nine chromosomal regions that had the strongest associations with generalised vitiligo. In their genotyping. known as the National Institutes of Health Genotype and Phenotype database. The results of this genotyping were compared with publicly available control genotypes from 2.

suggesting that multiple genes are involved in susceptibility to this condition. It will take further research to understand this genetic association and how it relates to the risk of skin cancer for those with vitiligo. the variants associated with increased risk of vitiligo were also associated with reduced risk of malignant melanoma. including people with vitiligo. Regardless. The researchers comment that their study shows little agreement with the associations reported in previous studies. although this is small. The other regions previously associated with other autoimmune diseases contained the genes PTPN22. The suggestion that increased risk of vitiligo is accompanied by a reduced risk of malignant melanoma is a puzzling result of the study. and one associated region contained the gene TYR. should avoid getting burnt by the sun. The acceptable levels for statistical significance in genome-wide association studies are higher than in other types of study. which reflects the fact that they can involve numerous statistical tests that can increase the likelihood that an association will be found by chance. However. their study is an important insight into the condition. which means it is highly unlikely they occurred by chance. called RERE and GZMB. All associations in this study were reported at the significance level of p less than 5 × 10-8. Two other associated regions contained additional immune-related genes. They say that the loci identified in this study together account for about 7. IL2RA. They say that the genes in some of these regions have been associated with other autoimmune diseases. All nine regions where these SNPs were found featured the same associations observed in the first set of samples. Visit Vitiligo Corner Visit Vitiligo Cover Lotion Page 38 . LPP. Most of the 50 SNPs tested in the two replication sets showed significant association with vitiligo in at least one of the sets.Vitiligo Corner 2010 Informed consent was obtained from all the study participants. UBASH3A and C1QTNF6. and variants in another region may be associated with both an increased risk of vitiligo and a reduced risk of melanoma. everyone. The associated SNPs mainly lay in regions that have previously been associated with other autoimmune diseases. which contains genes important for the immune system. The most strongly associated SNPs lay in the region called the major histocompatibility complex.4% of the total genetic risk for vitiligo and that. but at this stage it is too soon to say if this means anything. How did the researchers interpret the results?The researchers concluded that they had identified genetic variants associated with generalised vitiligo in multiple chromosomal regions. ConclusionThis study is one of the first to comprehensively establish areas of genetic code that may be involved in development of generalised vitiligo. What were the basic results? The researchers found that nine chromosomal regions contained SNPs associated with generalised vitiligo. Two of the associated SNPs in the region containing the TYR gene had previously been associated with susceptibility to malignant melanoma.

6248748.jp Last Updated: 22 April 2010 11:09 AM Source: NHS Choices Visit Vitiligo Corner Visit Vitiligo Cover Lotion Page 39 .Vitiligo Corner 2010 found on: http://www.uk/nhscancer/Pigment-disease-39reduces-cancer-risk39.sheffieldtelegraph.co.

but obviously you all need to assess what risks you are prepared to take to achieve re-pigmentation.Vitiligo Corner 2010 Vitiligo repigmentation success 18 Comments It is my great pleasure to share with you some fantastic repigmentation results sent in by Bryn. I think the 3 methods I use are the most natural I could use (apart from the UVB which you could replace with natural sunlight I suppose) If anyone else is taking photos of their progress. I think it would be a great moral boost to other sufferers to see some photos of progress that people have made. Also. Hi everyone Here are the photos of the recent repigmentation in one of my patches of vitiligo on my inner thigh. I used Ginkgo Biloba combined with ground piperine (using E45 as a Base Cream) and also using Narrow Band UVB handheld lamp. Regards Bryn Visit Vitiligo Corner Visit Vitiligo Cover Lotion Page 40 . or it may be a combination of therapies which work well together. This regimen appears to work for me. so don’t be shy and show off your re-pigmentation. its impossible for me to say with any certainty whether the Ginkgo is doing the re-pigging or indeed any of the others.

you not crazy I feel the same way # 1 September 2010 at 7:28 am * zz said: hi what picture looks worst then upper one?? Visit Vitiligo Corner Visit Vitiligo Cover Lotion Page 41 ..Vitiligo Corner 2010 18 Comments » Mary said: Has anyone heard of “ReCell”? Here is the link http://www.php?ob=1&id=1 This sounds amazing. let me now what all of you think. # 1 September 2010 at 4:20 am * lee ha said: Jon.avitamedical. # 3 August 2010 at 10:06 am * Jon said: Am I crazy? The lower picture looks slightly worse than the upper.com/index.

it is a bit difficult to discern the new pigmentation. Sorry for the late response.com (author) said: man. lol. Hey Bryn. # 1 September 2010 at 12:12 pm * Visit Vitiligo Corner Visit Vitiligo Cover Lotion Page 42 . I work at CDC as their computers support person. i have re-posted the photos so that you are now able to click on them for an enlarged image.Vitiligo Corner 2010 # 1 September 2010 at 8:32 am * lee ha said: the bottom pic looks worst to me # 1 September 2010 at 8:48 am * Nathalie Pelletier vitiligocover. it is the subtle darkening around the edges that is the tell sign. any new developments? # 1 September 2010 at 10:45 am Lee Ha said: Hi Nat. :) # 1 September 2010 at 8:48 am * Mary said: there is definitely re pigmentation happening. i can see that the after photo is correct. you guys are making me work this morning. but as someone who has experienced repigmentation.

# 2 September 2010 at 6:56 am * zz said: hi lee ha what treatment are you doing now???i need abit of help because it on my face and the hair grow out its white.gov send me the email and I will send my before and after pics to you.. I like to post my version of before and after pics of my treatment can you give me your email address or tell how to uploaded the photo on here. thanks # 2 September 2010 at 7:05 am * Lee Ha said: for ZZ.please help. and beer.flaxseed.cooper. I also using protopic twice a day and narrow band uvb twice a week. for vitamins i’m taken vitamin e.b-12 and b-complex. # 2 September 2010 at 7:54 am * Visit Vitiligo Corner Visit Vitiligo Cover Lotion Page 43 .zinc.Vitiligo Corner 2010 Lee Ha said: Hi Nat. spicy food. I see big improvement my spots almost completely gone!!! for the last five month I don’t eat any red met.. I ate lots of veggie all types of veggies 80/20 80% veggies and 20% white meat or fish with Omega only.folic acid. I drink water like crazy hope this help you little bit.L-Phenylalanine. my email is jut9a(insert the @ sign here)cdc.d. I drink carrot juice twice a day in the morning and before bedtime.

Did you buy a powder form of peperine and ginkgo biloba. where did you get it? Do you mix it evertime you use it or do you make a batch? Or do you take some pill for peperine and ginko biloba? Thanks # 22 September 2010 at 8:31 am Visit Vitiligo Corner Visit Vitiligo Cover Lotion Page 44 . I guess once you write a long note she has to check it before it become available. i have reply back to you a long list of things to do but I guess we have to wait for Nat to release them since she oversee the site. # 2 September 2010 at 8:42 am * MA said: How do you make your cream with (Ginkgo Biloba combined with ground piperine (using E45 as a Base Cream).Vitiligo Corner 2010 Lee Ha said: ZZ.

· On-site processing for immediate application. reconstructive. eliminate tissue rejection and reintroduce pigmentation into hypopigmented areas. melanocytes. (Vitiligo results here. the cell suspension is available for immediate use and can cover a treatment area up to 80 times the area of the donor biopsy. about halfway down page) Developed as an ‘off the shelf’ kit. iatrogenic hypopigmentation and Vitiligo) and in aesthetic rejuvenation procedures. autologous cell harvesting. donor sites. ReCell enables a thin split thickness biopsy. easy-to-use proprietary ’spray-on’ application process. morbidity and healing time. Advantages include: · Minimization of donor site size and depth with concomitant reduction in complications. fibroblasts and Langerhans cells harvested from the epidermal-dermal junction for application onto a wound surface in order to promote rapid and effective healing. taken at the time of the procedure. hypopigmentation (hypopigmented scars. ReCell has been clinically demonstrated to accelerate healing. · Improved wound healing time and scar quality. Visit Vitiligo Corner Visit Vitiligo Cover Lotion Page 45 . · Repopulation of melanocytes to reduce hypopigmentation. plastic. glabrous injuries. mild to moderate scars. ReCell has been designed for use in a wide variety of wound. ReCell enables the delivery of keratinocytes. rapid. to be processed into an immediate cell population for delivery onto the surface of the treatment area using a highly efficient. the process is both cost and time efficient. processing and delivery technology that enables surgeons and clinicians to treat skin defects using the patient’s own cells in a regenerative process. Tissue collection. As the ReCell technology enables cell processing at the site of treatment without the use of specialized laboratory staff. burn and cosmetic procedures including burns and scalds. Once processed. cell segregation and preparation of the cell suspension takes approximately 20-30 minutes in total during which time the treatment area is prepared.Vitiligo Corner 2010 Vitiligo solution near with Avita’s “Recell”? 36 Comments ReCell® is a stand-alone. minimize scar formation.

· Ability to be processed by clinician and not require specialised laboratory staff.Vitiligo Corner 2010 · Increased viability through immediate harvest and application. taken straight from their site: http://www.com/ I’ve compiled a list of sites with more information: ReCell on vitiligo photos US Recell Spray-on-Skin Enrolment Commences Avita First U.452M FROM US MILITARY TO SPEED DEVICE APPROVAL. Visit Vitiligo Corner Visit Vitiligo Cover Lotion Page 46 .S.avitamedical. Treatment Burn Victim With ReCell Avita ReCell product approved in China AVITA GETS $1.

# 8 August 2010 at 4:00 pm * Dawn said: Im really excited to hear about this :) Also. Isn’t it exciting! All the best # 7 August 2010 at 9:38 pm * DJ said: Thanks Natalie. Thank you!!!! # 9 August 2010 at 6:47 am Visit Vitiligo Corner Visit Vitiligo Cover Lotion Page 47 .Vitiligo Corner 2010 36 Comments » Mary said: Oh that’s great Natalie. just received your Vitiligo Cover Lotion for the first time and it works great! I am very pleased. and I was impressed with the results. Checked out their website. researched their case studies. Plan to reorder again. that you ran this story. This technology seems to be a promising step forward toward a cure for vitiligo.

com (author) said: Hi Ven. Visit Vitiligo Corner Visit Vitiligo Cover Lotion Page 48 .. Let me know if you have ever started a Clinical trial process. # 10 August 2010 at 9:00 am Nathalie Pelletier vitiligocover. I will email her in the evening and I will copy you. Regards. I requested them if I can use the product which they said is not possible for the next two years. Just called the company they are currently doing two clinical trials for SCARS and BURNS. and remember the real cure its inside of you! # 10 August 2010 at 4:23 am * VEN said: Natalie. I suggested that we can request as a group for a new clinical trial for vitiligo she said that it is a good approach and she will raise that with their team.Vitiligo Corner 2010 Sebastian said: Hi there i’ve been a vitiligo patient for 3 years and its speeding up now faster than ever! i live in a country where medication and information is scarce. i was wondering how well does the lotion work? # 9 August 2010 at 10:51 am * joel said: Does Somebody alreay test it on vitiligo? whats the results? Seems a futuristic thing eheh cheeersss Nice! we got to have more information about this specific on vitiligo.

What makes them more confident now.Vitiligo Corner 2010 well done! i’ve never been a part of a clinical trial.) # 11 August 2010 at 9:12 am * Mary said: Natalie. We’re stronger than Vitiligo. I did some research about this and I found some stuff dating back to 2006. so exciting. I’m in. is it due to good results from clinical trials? I hope so. i will do anything i can to help our with this . # 11 August 2010 at 5:55 pm * Dan said: This is good news.D I would love to be in too. # 11 August 2010 at 9:47 pm * Visit Vitiligo Corner Visit Vitiligo Cover Lotion Page 49 . even if it’s 2 years away. Your website is making a difference. once and for all. # 11 August 2010 at 10:18 am * FD said: Greattttttttt newsssssssssss . As a group we can be a powerful force and help to eliminate this disease. however.

* SV said: This treatment looks very promising…It gives one hope and the belief that research can help in finding a cure… Visit Vitiligo Corner Visit Vitiligo Cover Lotion Page 50 # 12 August 2010 at 6:14 pm . or the fact that we can’t have access to it yet. # 12 August 2010 at 7:31 am * drew said: It sounds promising but…I think calling it a cure is kind of misleading. or could it come back? I’m praying it’s permanent. Treatment is probably a more accurate way of putting it. If it turns out to be an effective treatment that is still really good news. # 12 August 2010 at 11:27 am * Mary said: Unbelievably exciting! Aren’t the photo’s encouraging? Even if it’s not perfect now.Vitiligo Corner 2010 Mary said: Dan. it is a step forward. did you happen to find out if this could be permanent. through your research. The research and advancements will only improve in the next couple of years. They will not stop now.

I am also pessimitic because I had it for 21 years and didn’t find any new medicine but we should try till we live and that is the approach I am headed towards. Natalie could you ask or send an email to national vitiligo or vitiligo secity uk to ask them do they know about this recell information. # 13 August 2010 at 8:07 am . If any of you live in Europe or Canada please check with the Avita counterparts and let us know.Vitiligo Corner 2010 # 13 August 2010 at 3:18 am * VEN said: All. I am optimistic because it is a new approach and it worked for similar ailments....if they dont know let they know…am sure if they know they could do something… # 15 August 2010 at 5:14 pm * Visit Vitiligo Corner Visit Vitiligo Cover Lotion Page 51 Regards. I will call Avita again on Monday and let her know if we can do a campaign (via email or blogging) to convince Avita and FDA for a CT.i only get information in there….. I inquired if we can get the pack from Canada but they knew for fact Canada doesn’t treat patients in India. I think we should give it a try if the Clinical Trial happens and hope for the best.i live in the uk and i hate the fat that alll the doctors dont care about us with vitiligo…only vitiligo society uk cares i think. I will post once I hear back from them. I was told that a clinical trial is very expensive. the phtoto in recell are amzing on the website… would this be decuss at the world conferess 2010…any make it avilible world wide. * zz said: hi Natalie does national vitiligo or vitiligo society uk know any of this information?????i think if they know about this they could do something about it…or make this treatment come out sooner….

Vitiligo Corner 2010
Dan said: Hey Mary I did not find out if it was permanent or not but I think if the majority of us could get back to one color with what we have learned could stay that way through healthy lifestyle but maybe im wrong…still though fingers crossed. # 15 August 2010 at 10:11 pm * Sebastian said: knowing i have vitiligo is making me more stressed than ever i need some kind of support here anything will help # 17 August 2010 at 11:13 am zz said: hi Natalie does national vitiligo or vitiligo society uk know any of this information?????i think if they know about this they could do something about it…or make this treatment come out sooner…..i live in the uk and i hate the fat that alll the doctors dont care about us with vitiligo…only vitiligo society uk cares i think..i only get information in there…. the phtoto in recell are amzing on the website… would this be decuss at the world conferess 2010…any make it avilible world wide.. Natalie could you ask or send an email to national vitiligo or vitiligo secity uk to ask them do they know about this recell information..if they dont know let they know…am sure if they know they could do something… # 17 August 2010 at 11:16 am *

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lee ha said: just to let you all konw I just called the company the said about 18 months recell will be available but it work only for stable vitiligo it is like MKTP # 18 August 2010 at 8:38 am Mary said: Hi zz Have a look at their website and you will see how it works. That will help you a great deal. Also, as lee ha just wrote, it will not be avail for 18months and then at that point they will probably start the clinical trials, I’m assuming. You should also call this company and ask them questions. It seems for now, your Vitiligo has to be stable, but that may change in the future, we don’t know. It’s all good. # 18 August 2010 at 12:23 pm * Sebastian said: THANKS FOR ALL THE HELP # 18 August 2010 at 12:29 pm *

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Nathalie Pelletier vitiligocover.com (author) said: thanks for doing and sharing, lee…we all appreciate your great effort! # 18 August 2010 at 12:31 pm

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Nonsegmental vitiligo (NSV). SCENESSE®. If approved by US and EU regulators. depigmented skin patches caused by vitiligo. Australia UV-protective drug to be tested for vitiligo SCENESSE® (afamelanotide) to be trialled as novel repigmentation therapy A drug initially developed to protect skin from light and UV will soon be tested as a repigmentation therapy in vitiligo. in skin. Visit Vitiligo Corner Visit Vitiligo Cover Lotion Page 55 . Dr Philippe Wolgen said. In vitiligo the pigment producing cells of the skin (melanocytes) are absent or inadequate. Vitiligo doesn’t cause physical impairment but does cause significant psychological and emotional distress. activating melanin in the skin to protect against damage. While testing SCENESSE® for other diseases. and biologically activates melanin for up to 60 days. The active ingredient in SCENESSE®.” Clinuvel’s CEO. “Our vitiligo program is a potential breakthrough for patients and testament to Clinuvel’s expertise in the field of dermatology and skincare: the activation of melanin. works by mimicking the body’s own response to ultraviolet light. The disorder affects up to 2% of the population. affects over 45 million people globally. a common disorder which causes skin to gradually lose its pigment or tone. will be evaluated for its ability to reactivate melanin in the whitened.Vitiligo Corner 2010 UV-protective drug to be tested for vitiligo 23 Comments More exciting news in the development vitiligo treatments was announced today. roughly the size of a grain of rice. afamelanotide. Clinuvel discovered that the drug may help vitiligo patients. including skin cancer. The drug is delivered as an injectable implant. a new drug developed in Australia. pigment. As a result. Media release Wednesday 25 August 2010 Melbourne. lighter patches of skin appear in different parts of the body due to a lack of melanin. the most common subtype. Melbourne-based Clinuvel Pharmaceuticals Ltd will commence trials in October.

“We are excited to be able to commence this trial and work with the vitiligo community to determine the drug’s effect. we understood SCENESSE’s ability to assist with repigmenting skin lesions. It is expected that SCENESSE® will enhance this therapy as well as activating melanin independently by stimulating specific melanocytes which exist in hair follicles within the skin.com/scenesse Australia T: +61 3 9660 4900 or Clinuvel AG (Switzerland) T: +41 41 767 45 45. SCENESSE® has been safely administered to approximately 550 patients and is in late stage confirmatory clinical trials in the US and Europe for the rare light intolerance porphyria (EPP).” Dr Wolgen said. .com Visit Vitiligo Corner Visit Vitiligo Cover Lotion Page 56 . “But. Dr Hank Agersborg. investorrelations@clinuvel. since the scientific reports came through on the effects of phototherapy in vitiligo.Vitiligo Corner 2010 “For a long time we were unsure of the potential of the drug in vitiligo.” To date. contact Clinuvel Pharmaceuticals Ltd.” SCENESSE® will be tested in a pilot NSV study on its own and in combination with an existing therapy called narrowband ultraviolet B (NB-UVB). http://clinuvel.End For more information. which uses UV light to activate pigment and restore melanocytes.” explained Clinuvel’s Chief Scientific Officer. “To be able to evaluate a potential therapy that could help improve quality of life for these people is a vastly rewarding prospect for Clinuvel. “Vitiligo is a disorder that has a considerable impact on the lives of patients worldwide.

I get so excited to let everyone know about it. or maybe even cured…… Whatever it is. there are clinical trials to go through—-BUT IT’S HAPPENING!!!! I really believe in my heart that soon. maybe transplanted or covered up so well that no one will ever know what we have. will be affected in some positive way by any one of these advancements.com (author) said: It does Mary. there is some sort of breakthrough! I know that it will still take some time. And each time I find new information for us. Maybe to stop it from spreading in our bodies. but if that’s the hardest part of what I do. lol. Natalie. doesn’t it make you giggle all day when you find these things! # 26 August 2010 at 2:03 pm * Nathalie Pelletier vitiligocover. it seems like once a month. I’m thankful! # 26 August 2010 at 2:11 pm Craig said: Hi Nathalie. that day will come. Visit Vitiligo Corner Visit Vitiligo Cover Lotion Page 57 .Vitiligo Corner 2010 23 Comments » Mary said: Since I have joined in on this website (bless Natalie). Sometimes it takes longer than I’d like to make the post because finding the perfect photo to accompany the article is very difficult. everyone of us here. in the fight against Vitiligo. it’s hope and hope is what let’s me wake up every morning and look at myself in the mirror and know that one day. in our lifetime.

I wonder. but in this case i do. do you know if this is a permanent solution? I couldn’t find the answer in my research. then the odds of re pigmentation are really good. Natalie. Anyway. if anyone else can find any info if this is a permanent solution or has to be done throughout the year. I do understand your pain… I am surviving for the past 27 years with vitiligo. What I did find very interesting is the information about the hair folicle. If the hair is still black and has not turned white in the effected area. I want to know if we can get this through mail orders or other means :) ZZ. Positive attitude brings positive results be optimistic. # 27 August 2010 at 9:30 am * VEN said: Guys. Did you contact the company.Vitiligo Corner 2010 This breakthrough really sounds very interesting. Visit Vitiligo Corner Visit Vitiligo Cover Lotion Page 58 . I just hope it can get clearance from FDA asap. if the implant would only activate the pigment around the area it was inserted or would it activate the full body ? Its not often i get a really good feeling about vitiligo treatments. it would greatly be appreciated.php?option=com_content&task=view&id=1111&Itemid=7 # 27 August 2010 at 9:09 am * Mary said: Natalie.com/index. # 27 August 2010 at 3:34 am * Kevin said: here is a link to a great video the company posted: http://clinuvel. this is indeed a great news… I have research on other treatments but this is a good break-through.

I want them to do the proper research and clinical testing. # 28 August 2010 at 7:33 am zz said: does anyone know when will this treamtent be aviliable. so that the FDA passes this. It’s probably not the only company making this type of product.in the uk there is not much treatment avilable... i included a link at the bottom of the post that goes to their website and their contact phone is listed. also. I think soon.com/clinuvel-q-a-a # 29 August 2010 at 11:15 am Visit Vitiligo Corner Visit Vitiligo Cover Lotion Page 59 . you will see more of this type of thing in the near future. we have to know that it’s safe for us.com (author) said: zz.Vitiligo Corner 2010 regards # 27 August 2010 at 9:07 pm * Mary said: I think we need to wait and see. This has been developed after years of research. they have a Q&A section that will answer some of your questions http://clinuvel. because of the increase of skin cancer. I personally don’t want this right away.and once this treatment is out will it be in the uk…what is the cost of this treatment anyway…i think this treatment is avilible in italy # 29 August 2010 at 10:58 am * Nathalie Pelletier vitiligocover. giving us many options. It is something we are injecting into our bodies.

# 30 August 2010 at 7:58 am VEN said: All. I will let you guys know if I hear from them. Regards.Vitiligo Corner 2010 * Nathalie Pelletier vitiligocover. they are not providing any information on ongoing trials for security reasons. He will be calling me in the near future and I will post pertinent information as it is available. I requested them for dermatologist’s in USA who are part of this trial they asked me to email them which I did and the email bounced back. it will answer your questions. I contacted their office in Melbourne. I gave them my email address so that they can email me. just browse around their site a bit and read the information.s for it’s use with vitiligo patients.I sent them an email from their website and called them today. # 30 August 2010 at 7:36 pm * Nathalie Pelletier vitiligocover.com (author) said: zz. or call them with the number provided at the bottom of my post. I just wanted to drop a quick note to let you know that I was contacted by email this morning by an executive at Clinuvel. the manufacturer of Scenesse. # 29 August 2010 at 6:18 pm * zz said: will this treatment be out in the uk???or do i have to go to usa to do the treatment???once its out.com (author) said: Hi. Visit Vitiligo Corner Visit Vitiligo Cover Lotion Page 60 . the post i made was from a press release that the company put out last friday and it explains all about the trials they are now doing in the u..

but now as an older adult I suspect people think I must be twice my age. So it must look great to strangers. i will post them here. i am sure the company must have a complete business plan concerning the distribution of scenesse. rest assured. new person I recently met thought I had survived a fire or some kind of horrible accident. As a teenager. I completely gave up a long time ago on any kind of effective treatment. If this stuff is legit seems like doctors would jump on it for their patients? Anyone else also diagnosed with multiple sclerosis? I wonder how two autoimmune disorders would respond to such a method? # 31 August 2010 at 7:06 pm Visit Vitiligo Corner Visit Vitiligo Cover Lotion Page 61 . chances are slim that they can share future plans. maybe a novel kick. as soon as there are answers. eh? Also.com (author) said: hi zz.Vitiligo Corner 2010 cheers and all the best! # 30 August 2010 at 8:05 pm * Nathalie Pelletier vitiligocover. but until they get approval. All I could do was laugh. It is also very resistant to dye so I don’t bother. at this early stage. there are no definitive answers to your (post fda approval) questions. my dark hair has gone completely white (starting when I was 17). # 30 August 2010 at 8:12 pm zz said: so we have to wait years again?? # 31 August 2010 at 8:43 am * Suzanne said: Had vitiligo for so many years and it spread so much.

Vitiligo Corner 2010 zz said: hi this looks really good but how long do we have to wait and does it cost alot…will this be in england too or just in usa. Clinuvel is working with four centres. Clinuvel intends to commence a pilot Phase II trial of SCENESSE® in individuals diagnosed with nonsegmental vitiligo. i really hope that this 2010 world congress is the beginning of new treatment and more effective treatment… while am here i want to thanx to nat for setting up this website …i really wish if the doctors are kind like you and take out vitiligo seriesly and help others… if they take vitiligo seresly long time ago maybe there would be a more effective treatment aviliable by now… fingers cross and see what this world congress going o bring for us…hope its a good one…. # 1 September 2010 at 4:39 pm * VEN said: All. two each in the USA and Europe. who will conduct the study. rather we work with physicians in the field to identify potential trial participants. No further centres will be considered for this initial pilot program. Thank you for your recent email to Clinuvel regarding our upcoming pilot study.. The company is yet to release details on trial participation. You can read the company’s full announcement here. Please note that we do not recruit directly for any of our clinical studies. Visit Vitiligo Corner Visit Vitiligo Cover Lotion Page 62 . I received email from Clinuvel Communications office…. Pending regulatory approval. The company has received a strong response from the community to its plans and I apologise for not being able to respond to your enquiry personally.

so we need to make sure this is (relatively) safe and to know what the side effects are before we jump on it. i.” (Don’t you love the sweet things the derms say to you?). # 5 September 2010 at 11:07 am * Betsy Morrigan said: I think that Clinuvel’s clinical trials with Scenesse is exciting news for us. let’s say it does that on the white patches AND our regular still pigmented skin. especially something like this they implant into your body as a time release capsule. I appreciate your patience as we progress with our vitiligo study. Kind regards. I would rather have vitiligo than cancer! This is not some kind of natural oil.’ just waiting to be depigmented. we don’t want to take it. you know. let’s hope! Until then. much browner tan against temporarily pink vitiligo patches. What I wonder about it is that if it increases melanin production. which can be done through this page on our website.Vitiligo Corner 2010 To keep abreast of our trial program for vitiligo.’ All your skin is ‘vitiliginous. Visit Vitiligo Corner Visit Vitiligo Cover Lotion Page 63 . there is no ‘regular skin. let’s face it. All medications have side effects. “Once you have vitiligo. We want this medication to be safe. you know! If this Scenesse causes cancer and other diseases like HRT ended up doing. Although my doctor said. It is a chemically produced intense medication.com/vitiligo. I think we should not bombard the company for vitiligo treatment info which they don’t have yet. Que sera sera. won’t it just increase the contrast in pigment by making the regular skin darker. and I am very glad that they are now testing this new melanin procucing medication for vitiligo.e. The company will release further details on its program when possible. we should let them do their work. all I get is much more contrast making it look worse. I don’t do this any more. You may also wish to sign up for email updates from Clinuvel. In a couple of years they might have some very good news for us.clinuvel. You see what I mean about increasing the contrast? Whenever I have used Vitiligo oil or other things -–even lots of celery–that make your skin more photosensitive. please continue to monitor our dedicated webpage at http://www.

It’s exciting for us that they’re now doing vitiligo clinical trials with this new medication now. I dearly hope that this product will bring back our lost pigment and be a permanent treatment for our problem.Vitiligo Corner 2010 So let’s be patient with this company while they safety-test their new product. # 25 October 2010 at 12:18 pm Visit Vitiligo Corner Visit Vitiligo Cover Lotion Page 64 .

are a priority. The drug development process – Part 1 of 3 As we’ve said before. We say ‘potentially’ because clinical trials require significant funding. Ultimately the lengthy processes and protocols are there for two important reasons: to ensure safety and effectively demonstrate the drugs effectiveness and efficiency (efficacy). the drug development process is long and complex. Research begins as a response to need. an idea. PK studies involve discovering what the body does to a drug. and actions since our conversation. This is where potential drugs start life. Last week I spoke at length with Head of Global Network and Communications at Clinuvel. metabolise (transform) or eliminate the drug? While PD studies concentrate on what the drug does to the body. Visit Vitiligo Corner Visit Vitiligo Cover Lotion Page 65 . I have noticed many comments asking how long it will be until we see this product on the market. There is always a measure of anticipation from the market and patients. There are also initial Pharmacokinetic (PK) and Pharmacodynamic (PD) studies. As per our earlier post. Frankly. but there is also an overwhelming amount of work involved. The first stage can be referred to as the initial development. it’s been clear that we.Vitiligo Corner 2010 The drug development process – Part 1 of 3 No Comment Since I posted the press release from Clinuvel about SCENESSE® (afamelanotide) to be trialled as novel repigmentation therapy. but on average takes a minimum of three years. but through his words. I felt like this is a company truly out to help people. a drug can potentially advance through to clinical development.000 discovered or researched will even get to this stage. Next comes the pre-clinical development stage. only 250 drugs from every 10. and by the end of our conversation. The length of time spent on initial and pre-clinical development varies greatly. This is where researchers assess toxicity and examine the effects of the drug. How does the drug react with naturally occurring chemicals and substances? What is it’s mechanism of action? Having shown promise in the first two stages. rigour and a drug with adequate scope and its own potential to become a successful and effective response to a medical need. I’m not saying that they don’t care about their bottom line. distribute. or all of the above. and only five will progress to the next. How does the body absorb. the “patients”. grants and requests from governments and foundations. so I was given this information to pass along as a guide for us all. there is no simple answer. I thought that it would be helpful if we understood the clinical trial process.

Vitiligo Corner 2010
In our next post, we’ll discuss the structure and process necessary for undertaking clinical trials that adhere to the standards set by regulatory bodies, and give drugs their best chance for progression. http://www.clinuvel.com/en/blog/pharmadev/the-drug-development-process-%E2%80

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The drug development process – Part 2 of 3
This is a continuation of the post “The drug development process – Part 1” Clinical trial development must follow a strict and comprehensive process and there are different objectives and focuses for each phase. Generally, phase I trials assess the toxicity of a drug, while phase II focuses on in-depth study of the drugs activity with the chosen condition or indication. Phase III aims to prove the drugs efficacy (efficiency) as a treatment or cure for a condition. However, the safety of the drug is a common consideration throughout the entire process. Apart from phase I, where the objective is to examine toxicity, the first requirement for a clinical trial is to develop a concept or question. This is where the ‘clinical endpoint’ is identified as a key element of the study. A clinical endpoint is a health problem, disease, disorder or condition that has the potential to be prevented, treated or cured by the drug being trialed. Following this, the trial must detail how the study will progress in relation to the trial question or concept. The trial process must adhere to local and regional regulatory requirements, governed by the regulatory authorities. These regulatory authorities oversee pharmaceutical development and ensure that trials are thorough, relevant and above all, safe. They carry out a range of assessment and monitoring activities to ensure pharmaceutical goods are of a high standard. They aim to ensure that access to new and effective treatments is available within a reasonable amount of time. The Australian regulatory agency, the TGA, sums it up well. “Although the methods for implementing and enforcing these principles vary across regulatory agencies, the end result, it is hoped, are trials that collect high quality, credible data that contribute to the answering of specific scientific questions, while most importantly protecting the rights, safety and well-being of clinical trial participants.” Separate from regulatory approval, a study must also gain ethical approval from the relevant ethics committee. These committees can be local to the study site, or governed by region, depending on where the study is taking place. An ethics committee will examine elements such as a trials risk to participants or the accuracy and clarity of information provided to patients in order to obtain their consent. A trial can only commence once it has received the necessary regulatory and ethical approvals. Usually the next step would be to recruit trial participants. Alongside this, staff and physicians must be trained in the trial protocol, including drug education and how to administer, manage and monitor the trial. Having completed all these steps, the first patient can be dosed.

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Vitiligo Corner 2010
Traditionally, phase I trials can be completed within months, while phase II trials average two years. A phase III trial is usually longer and more intensive, and these have been known to last up to five years or more. Interestingly, the approved trial length does not reflect how long the trial will take in real terms. Trial length actually indicates the amount of time a participant is involved in the trial for the study to be considered complete. Not all participants start at the same time, so a 12 month study could take more than two years depending on when the first and last patients begin their dosing. Following the completion of the each trial there are detailed and rigorous data collection and analysis stages to confirm the trial has answered the research question. Then there is the collating, writing and publication of discoveries, research papers and trial results and conclusions. Finally, the trial dossier is compiled and submitted to the regulatory body with the goal of receiving approval and proving the case that trials should progress to the next phase of the development process. This is post 2 of 3 on the drug development process. Click here for part 1 http://www.clinuvel.com/en/blog/pharmadev/the-drug-development-process-part-2/

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This phase aims to provide a definitive study of the treatment. or the treatment is discovered to be not practical or efficient. to prove that the new treatment is its equal. All trials must undergo the same rigorous process as outlined in our previous post. If the drug is proved safe and well tolerated in phase I. This phase is often the point at which drugs fail. it will progress to phase III. These trials normally consist of a small number (20-100) of healthy volunteers and usually include studies on ways of administering the substance.Vitiligo Corner 2010 The drug development process – Part 3 of 3 3 Comments This is a continuation of the post “The drug development process – Part 1” and “The drug development process – Part 2? The 3 Phases of clinical trials are strictly monitored and controlled by different regulatory bodies such as the FDA (US). be effective in preventing. Upon completion of the 3 Phases. During this phase adverse events are monitored and optimal dosages are assessed. the TGA (Australia). Visit Vitiligo Corner Visit Vitiligo Cover Lotion Page 69 . the results and findings of the entire development process are compiled into a dossier for submission to the relevant regulatory body. the EMEA (EU) and SwissMedic. It is estimated that the entire process costs an average of $500 million and for every five drugs that reach Ph III trials. as they prove to be ineffective on the chosen indication. just one will be approved for market. This phase traditionally consists of 100-1000 patients and has a maximum trial length of two years. where the different amounts of the drug are administered to help ascertain the optimum balance of effectiveness versus adverse events (side effects). Alongside that are extensive PK and PD studies (more detail in part 1). The primary focus is on the drugs efficacy and the gathering of statistical proof of efficacy. If a drug shows that it is effective in treating an indication. dose ranging. hopefully to receive a Marketing Authorisation Approval (MAA). Phase II trials involve assessing the activity of the drug on patients suffering from a specific disease or disorder (indication) where the clinical trial may lead to scientific evidence. treating or curing the condition. or better. and if there is an existing treatment for the indication. or dose escalation. where the focus is on the substances ‘activity’. the drug will progress to phase II trials. Phase I trials are carried out on healthy volunteers and are primarily focused on exploring the drugs potential toxicity and tolerability in humans. but are quite distinctly different and influenced by a number of other factors. These trials can involve between 1000 and 5000 patients and run for several years.

clinuvel. it is then necessary to run phase IV trials.com/en/blog/pharmadev/the-drug-development-process-part-3/ Visit Vitiligo Corner Visit Vitiligo Cover Lotion Page 70 . Following the granting of MAA and the drug becoming available. Click here for part 1 And here for part 2 http://www. which monitor long term and widespread use of the drug for several years.Vitiligo Corner 2010 And it doesn’t end there. This is post 3 of 3 on the drug development process.

As a result. SCENESSE®. afamelanotide is able to mimic the effects of the natural occurring ?-MSH. the Australian company Clinuvel announced that it would commence a clinical trial of a new drug for vitiligo. Afamelanotide’s chemical structure differs slightly from natural ?-MSH: it has been altered to increase the peptide’s half-life (increasing the length of time it can exist in the blood stream from seconds to minutes) and to increase its ability to bind to MC1R on the melanocyte. the clinical trial process. and when it will be offered world-wide. ?MSH is our body’s response to skin damage from ultraviolet (UV) light. Media Communications & IT Team @ Clinuvel. The active ingredient in SCENESSE® is a peptide called afamelanotide. The company has received a large number of questions related to its proposed trial and has released this Q&A to help people understand the potential. Here is the interview: Recently. In nature.Vitiligo Corner 2010 Interview with Clinuvel 10 Comments Recently I’ve had the great pleasure of speaking with Lachlan Hay. ?-MSH binds to receptors (specifically melanocortin 1 receptor or MC1R) in the skin on particular skin cells. which in turn activate our skin’s pigment. Clinuvel has refined afamelanotide’s formulation and chemical structure to reach the current drug formulation: a 16mg afamelanotide controlled release implant. of its program. melanocytes. how it works. Hay was kind enough to answer every question in detail. I had many questions about Scenesse®. Head of Global Network and Communications. melanin. Melanin provides skin cells with color as well as a biological barrier to protect them from UV and light. SCENESSE® has been formulated to achieve the Visit Vitiligo Corner Visit Vitiligo Cover Lotion Page 71 . Clinuvel has focused primarily on a drug called SCENESSE® (afamelanotide) which is an injectable implant drug roughly the size of a grain of rice. and potential limitations. This is an analogue of a naturally occurring hormone called alpha-Melanocyte Stimulating Hormone (?-MSH). with a longer lasting effect and increased potency. Who is Clinuvel and what is your drug SCENESSE®? Clinuvel is an Australian biopharmaceutical company developing drugs for individuals with a range of dermatological conditions. The skin is visibly darkened when melanin production is activated by ?-MSH. Mr.

demonstrating the important role of ?-MSH in the disorder. which will evaluate SCENESSE’s ability to repigment skin both as a standalone therapy and as an adjunctive therapy with narrow-band ultraviolet B (NB-UVB) light therapy. trialing the drug for the first time as a repigmentation therapy in individuals diagnosed with nonsegmental vitiligo. The drug is only present in the body for approximately ten days however the effect of the drug is seen for 60 days. Visit Vitiligo Corner Visit Vitiligo Cover Lotion Page 72 . in current clinical trials. Pending the outcome of this confirmatory program – due to complete in the first quarter of 2011 – Clinuvel expects to file SCENESSE® for Marketing Authorisation Approval (MAA) with European regulators. which mimics the effects of the naturally occurring hormone ?-MSH. is expected to restore this deficient system. To date. SCENESSE® has been shown to reduce the number and severity of phototoxic reactions in late stage trials of the drug in individuals with EPP and a confirmatory program is underway in the US and Europe. two each in the US and Europe. SCENESSE’s visible effect can be seen: the skin becomes darker. In August 2010.Vitiligo Corner 2010 optimal dose for activating melanin production systemically. Recent research studies have highlighted numerous ?-MSH and MC1R abnormalities in the blood and skin of patients with vitiligo. SCENESSE®. and thus provide efficient therapeutic repigmentation for the patients. log onto http://www. The company is currently making submissions for regulatory and ethics approvals to commence a pilot Phase II study in four centers. SCENESSE® is administered by physicians in the fatty tissue just above the hip. Hence. SCENESSE® is administered once every 60 days. a rare metabolic disorder which causes absolute light intolerance. Approximately two days after administration. For the past five years.com How do you expect SCENESSE® will work to repigment skin in vitiligo? The mechanics the vitiligo are still poorly understood. nausea and headaches are the primary side effects reported in clinical trials however the drug has been safely tested in approximately 550 individuals with no reports of serious adverse effects. SCENESSE® has been trialed for a number of UV and light related skin disorders (conditions called photodermatoses). To read more about our work. The most advanced of these programs is for an indication called erythropoietic protoporphyria (EPP). while minimizing exposure to the drug and thus reducing possible side effects.clinuvel. Clinuvel announced it would commence a new program for SCENESSE®.

com/vitiligo on whether individuals can register their interest to participate in trials. It is anticipated that. These criteria are determined by the company and/or physicians running the trial and approved by regulatory and ethical authorities.clinuvel. How can I participate in the trial? Can I register with Clinuvel? Every clinical trial has inclusion and exclusion criteria which dictate which individuals can participate in a clinical trial. Once regulatory and ethics approval has been granted. Visit Vitiligo Corner Visit Vitiligo Cover Lotion Page 73 . Clinuvel is yet to announce inclusion and exclusion criteria for the pilot trial of SCENESSE® in vitiligo. Clinuvel advises individuals with vitiligo to talk to their treating physician which is the best appropriate person to talk to for the different treatment options for their vitiligo. more specific information will be made available on these centers. once approved by regulatory and ethical authorities. The company cannot respond to individual requests to be involved in the pilot study of SCENESSE® in nonsegmental vitiligo. including clinical trials. Where will the trial be run. in which countries? Clinuvel intends to commence the pilot trial at four leading vitiligo centers: two in the US and two in Europe. The company has received significant input and encouragement from leading vitiligo experts worldwide for the use of SCENESSE® as a repigmentation therapy and eagerly awaits the chance to assess the drug in nonsegmental vitiligo. Once regulatory approval has been granted. Clinuvel does not recruit trial participants directly.Vitiligo Corner 2010 SCENESSE® as an adjunctive therapy with NB-UVB phototherapy may also speed up and assist the repigmentation process initiated by phototherapy and possibly reduce the doses of NB-UVB radiation. the proposed trial will not look to recruit many participants. further information will be made available on http://www. As a pilot study. as to do so may jeopardize the integrity of data generated in clinical trials. Clinuvel has created a video to help explain this process in greater depth. the four centers involved in the trial will look to recruit trial participants from their existing patient groups. No other sites are being considered for this trial.

to reach a satisfactory conclusion. This complete process often requires some negotiation between the sponsor. Until the company has analysed these results. Will Clinuvel run further trials in vitiligo? When will SCENESSE® be approved for use in vitiligo? Clinuvel expects results from its pilot study in vitiligo during the second quarter of 2011. such as the FDA in the US or the TGA in Australia. Clinuvel will first announce its results to the ASX through a formal announcement. but generally requires the sponsor to present a clinical study protocol. see part 1. Clinuvel has published a three part series on its blog entitled The Drug Development Process to read these posts. before posting them on the company’s website at http://www.clinuvel. and the regulator. it must seek approval from the governmental departments or agencies which regulate or control new drugs in a given country or jurisdiction.Vitiligo Corner 2010 When and how do you expect to release results from the pilot vitiligo study? Clinuvel expects to complete the pilot study of SCENESSE® in vitiligo and publish results from this study during the second quarter of 2011 (1 April-30 June). To help with understanding the clinical trial process. and provide scientific rational for their planned trial. What is ‘regulatory and ethics committee approval’? How long does this take? Whenever a company or physician (a ‘sponsor’) wishes to assess a drug in a clinical trial. the physicians involved in the trial. These documents must show that the necessary regulatory guidelines related to clinical trials are being followed in the trial protocol. As a public company listed on the Australian Securities Exchanges (ASX). Clinuvel also maintains relevant information on Pharmaceutical Development on its website. it is not feasible to make any projections on future trials or approval dates. which outlines the specifics of the study. The relevant regulatory agency will review the study protocol and scientific rationale and determine whether the study should proceed.com. This process varies from country to country. the Ethics Committees at individual study sites will reviews the protocol to ensure it meets the ethical standards of the particular institute or hospital conducting the study. During or shortly after the regulatory approval process for the study protocol. On this site you can view previous examples of results being released by the company. part 2 and part 3. The protocol is also reviewed to ensure it meets Good Clinical Practice or GCP standard. Visit Vitiligo Corner Visit Vitiligo Cover Lotion Page 74 . Generally this process takes 1-3 months.

see this webpage. The 648/96 listing allows Italian physicians to prescribe SCENESSE® to Italian citizens diagnosed with erythropoietic protoporphyria (EPP). SCENESSE® cannot be obtained outside of Clinuvel’s clinical trials anywhere else in the world.clinuvel.com/vitiligo Visit Vitiligo Corner Visit Vitiligo Cover Lotion Page 75 . How can I find out more about Clinuvel’s program for vitiligo with SCENESSE®? Log onto http://www. For more information on this scheme.Vitiligo Corner 2010 Is SCENESSE® available for purchase anywhere in the world? Currently SCENESSE® is only available by a physician’s prescription in Italy under a law called 648/96.

Can we know . I will write a post on it for tomorrow. which medical centers are involved in the clinical trials so that we can directly approach them. Thanks. this is a great question.com (author) said: Hi Ven.Vitiligo Corner 2010 10 Comments » VEN said: Natalie. regards # 17 September 2010 at 9:06 am * Nathalie Pelletier vitiligocover. I requested Clinuvel and they wouldn’t give that information… they only say to visit their website. :) # 17 September 2010 at 10:17 am * Vig said: Hi Nathalie. Visit Vitiligo Corner Visit Vitiligo Cover Lotion Page 76 . Vig # 19 September 2010 at 2:15 pm VEN said: Vig. Do you know what they mean by nonsegmental vitiligo?I want to know if I have nonsegmental or just regular vitiligo. but you can see photos immediately if you do a google search.

it sounds as though Scenesse will be an adjunct to NB UVB treatment. she has been a nervous wreck since this appeared all over body just over a year ago. From the Clinuvel website. I was curious.thanks for the information :) # 3 November 2010 at 3:59 am * Sue said: Hi Anita. I am excited about this possibility too. why exactly do you think your daughter started depigmenting? Since we both have kids close in age with the same skin condition. I hope it does work! Maybe we’ll have a great treatment then. # 3 November 2010 at 8:37 am Visit Vitiligo Corner Visit Vitiligo Cover Lotion Page 77 . Regards. # 7 October 2010 at 2:11 am * Anita said: My 8year old daughter would be sooo happy at the thought of a cure. thank you so much for this informative interview.Vitiligo Corner 2010 I found that Derm’s in Italy can prescribe can anyone in Europe/Italy get in touch with them and let us know ? V # 19 September 2010 at 6:14 pm * Betsy Morrigan said: Nathalie. I thought. may be we could keep in touch with posts as to what we are doing to treat them. but I say to all of us…Be careful…don’t rush into it! let them do their clinical trials and see if it works for vitiligo and if it’s safe. My 7 year old daughter too has vit. spreading rapidly.

no spices.com said: We need to be careful here. no red meat. mild exposure to sunlight…see if that helps. many kids them like them. # 3 November 2010 at 1:08 pm Visit Vitiligo Corner Visit Vitiligo Cover Lotion Page 78 . If I had a child with vitiligo.Vitiligo Corner 2010 Betsy Morrigan hawaiipackandpaddle. Don’t try to treat yourself with Scenesse until we see what the side effects are. Let Clinuvel finish their clinical trials and publish the side effects. I would also send them to a vitiligo children’s summer camp so they would not feel so isolated and so they could see that it affects many. vegetarian diet. but let’s remember that any drug that has the power to switch on our melanocytes and turn our skin darker will also carry big side effects! I ask myself all the time and I ask you: Which would you rather have: cancer or vitiligo? For children right now. We’re all excited about this new drug Scenesse. I would go with the tried and true: nb uvb. They could be very serious including skin cancer.

These definitions are my summarizations of the definitions I have read in medical journals and books.Vitiligo Corner 2010 What is segmental & non-segmental vitiligo? 2 Comments I’ve had vitiligo for over 14 years and a few weeks ago. so I thought I’d share what I learned about them with you here… and I’m going to put it in layman’s terms.a.) and increase in size over time. etc. so you could have both. And finally. NSV and SV can coexist. remember that I am not a doctor and I have had no formal medical training.k. I don’t even know the difference between segmental and non-segmental vitiligo. This is classified as Mixed vitiligo. vitiligo vulgaris and NSV) is the most common of the 2 types of vitiligo. After reading this. both elbows. both hands. I figured that I can’t be the only one who never looked into this. 2 Comments » VEN said: Visit Vitiligo Corner Visit Vitiligo Cover Lotion Page 79 . symmetrical (if it’s on one side of your body. eg. Non-segmental vitiligo (a. after reading that Scenesse® works on non-segmental vitiligo.k. to confuse matters when self-diagnosing. Segmental vitiligo (a. SV and asymetric vitiligo) looks like NSV but the term Focal is used because it is a limited area. It is often characterized by white patches that are generalized (seen anywhere on your body). I realized that not only do I not know what type of vitiligo I have.a. it’s in the same place on the other side. both feet.

Vitiligo Corner 2010 Nat. V # 18 September 2010 at 11:20 am * lee ha said: is it true they say segmental vitiligo has nothing to do with autoimmune? Visit Vitiligo Corner Visit Vitiligo Cover Lotion Page 80 . thanks a lot Natalie… I am surprised/confused/irritated because its been 27 years and I dont know about my vitiligo at the same time it is funny because I might have visited lot of doctors and they didn’t know this either :) cheers.

The success. Patient numbers will vary. a drug developer will then seek approval to sell the drug from regulatory agencies. During Phase I the focus is on safety. the drug will progress to phase II trials where the focus is on the substance’s ‘activity’. which organs are targeted and aim to discover the drug’s ultimate safety profile. or otherwise. There are three phases of human clinical trials prior to the drug applying for Marketing Authorisation Approval (Phases I-III) and one phase which commences when the drug is approved and available (Phase IV). These trials normally consist of a small number of healthy volunteers (20-100) and usually include studies on ways of administering the substance. dose ranging. Alongside this are extensive PK and PD studies. while Phase III trials confirm this data. pre-clinical trials are undertaken. generally at the request of a regulatory agency. Performed under strict regulatory and ethical guidelines. normally in a small patient population. If the drug is proved safe and well tolerated in phase I. Visit Vitiligo Corner Visit Vitiligo Cover Lotion Page 81 . These trials focus on examining the drug’s toxicity. or dose escalation. however. clinical trials form the majority of a drug development program’s time and cost and can involve thousands of patients over many years. based on a set of scientific parameters determined prior to the trial. of a drug hinges on the results gathered from these clinical trials and subsequent analysis and research. Phase I Trials Phase I trials are carried out on healthy volunteers and are primarily focused on further exploring a drug’s potential toxicity and tolerability in humans. This phase traditionally consists of 100-1000 patients and has a maximum trial length of two years. and optimal dosing and delivery method are explored and refined. according to the rarity of the indication being studied in the trial. where the different amounts of the drug are administered to help ascertain the optimum balance of effectiveness versus adverse events (side effects). with specific goals established for each ‘phase’ of the clinical trial process. further understanding and seek to confirm evidence of efficacy in a larger patient populations.Vitiligo Corner 2010 What goes on during clinical trials? No Comment Clinical trials are formal medical tests of a drug in a clinical setting. Once a drug is identified as having therapeutic potential through research or discovery. Should a drug prove both safe and effective in clinical trials. The goal of any clinical trial is to determine a drug’s effects on the human body. such as a hospital. A key area of exploration during Phase II trials is discovering and quantifying a drug’s ‘efficacy’ (effectiveness) in treating a condition. to monitor a drug’s safety profile and effects in humans. Phase IV studies monitor a drug’s ongoing safety and efficacy over extended periods of time. such as the FDA or EMA.

to prove that the new treatment is its equal. treating or curing a condition. and if there is an existing treatment for the indication. without posing an unacceptable risk to the patient population. During this phase adverse events are monitored and optimal dosages are assessed. Phase II is often the point at which many drugs fail to meet clinical trial endpoints. while continuing to monitor safety. Visit Vitiligo Corner Visit Vitiligo Cover Lotion Page 82 . or better. than can be included in clinical trials prior to approval of the drug. If a drug shows that it is effective in treating an indication.Vitiligo Corner 2010 Phase II Trials Phase II trials involve assessing the activity of a drug on patients suffering from a specific disease or disorder (indication) where the clinical trial may lead to scientific evidence that a drug is effective in preventing. as they prove to be ineffective for the chosen indication or the treatment is discovered to be impractical or inefficient. Their role is to monitor a drug’s safety and efficacy over a longer amount of time. These trials can involve between 1000 and 5000 patients and run for several years. The primary focus is on a drug’s efficacy and the gathering of statistical proof of efficacy. Phase IV Trials Phase IV trials are carried out after authorisation has been granted by a regulator and a drug is on the market. often Phase IV trials are a requirement of a drug’s approval. it will progress to phase III. Phase III Trials Phase III trials aim to provide a definitive study of a drug. and with a broader group of patients.

we also need vitamin B12 in order to be able to absorb folic acid.Vitiligo Corner 2010 Is there a connection between gluten intolerance and vitiligo? The possibility of gluten intolerance being connected to vitiligo has been brought up many times. Here’s what I’m thinking…If I have a gluten intolerance for a long time. Vitamin B12 is injected straight into the patient’s blood. on this site and in medical journals. rye. All that said. and I’ve read some cases where patients have received B12 injections repigmented. this is simply a hypothesis based upon my research. I went on to find that gluten intolerance (a. the melanocytes might just die away and not be replenished. Melanin (substance that gives the skin its color) is created by cells called melanocytes. do I need to be concerned about sunscreens. the melanocytes cannot properly perform the function of creating melanin. I dug a little deeper into what causes B12 deficiency and found that those with the disorder are unable to produce enough of a protein substance . that could have caused a B12/folic acid deficiency due to malabsorption of these vitamins from my regular diet. Next. We already know that that many people with vitiligo have a Folic Acid and/or B12 deficiency. Are you still with me? lol. Additionally. and possibly oats. Celiac disease ) is an inherited. and the theory makes a lot of sense to me because of the similarities I see with other issues known to be connected to vitiligo. autoimmune disease in which the lining of the small intestine is damaged from eating gluten and other proteins found in wheat. This causes a depigmented spots on the skin…vitiligo.a. therefore bypassing the stomach which is unable to absorb it properly.IF (intrinsic factor) – in their stomach that allows their body to absorb vitamin B12. When there is a vitamin B12 deficiency in the body. Apart from creating red blood cells and keeping our nervous system healthy. This in turn May have contributed to the onset of vitiligo because B12 is a crucial catalyst for the cell division process. shampoos and cosmetics that contain gluten? Visit Vitiligo Corner Visit Vitiligo Cover Lotion Page 83 . Can gluten be absorbed through the skin? Question If I have celiac disease. but I thought that I would share it with you in case it might help in our quest to regain even coloring of our natural skin tone. barley.k.

It is possible to have an allergy to wheat or another grain that could cause a skin reaction. If you use a cosmetic or skin care product that contains gluten and you develop a skin reaction. check the ingredient list on the product label or call the manufacturer. blistering rash.Vitiligo Corner 2010 Answer from Michael Picco. which causes an itchy. DH is caused by ingesting gluten. see your doctor or dermatologist to identify the cause. avoid using such products on your lips or around your mouth. For this reason. Also. But although it involves the skin. If you’re uncertain about whether a product contains gluten. eliminating gluten from your diet will help clear up DH as well. not by skin contact with gluten. No. avoid using gluten-containing dental products. Gluten-containing skin care products and cosmetics aren’t a problem unless you accidentally swallow them. Visit Vitiligo Corner Visit Vitiligo Cover Lotion Page 84 . This skin disorder is also linked to gluten intolerance. Some people develop a form of celiac disease called dermatitis herpetiformis (DH). such as certain mouthwashes and toothpastes. So. M.D.

Mental health and quality of life were two main themes central to the conference. Finally. a global effort to identify possible genetic variations which contribute to vitiligo. Several major issues struck our attendees and may have ramifications for our ongoing work in the field of vitiligo. This was perhaps best surmised by Don Verze (founder of the San Raffaele Hospital hosting the conference). Given the many unknowns in vitiligo – causality. For many readers.Vitiligo Corner 2010 Vitiligo World Congress 2010 – thoughts and reflections 38 Comments Late last week. this will not come as a surprise. In terms of treatment efficacies. designed to address both physicians’ and patients’ requests for new therapies and to enhance understanding of the disease. but long term follow up has shown that treatment effects are frequently short lived and depigmentation eventually reoccurs. Of particular interest was the vitiligo GWAS study. with one of the three days being entirely devoted to patients. particularly how best to design a trial for a therapy or treatment which will produce a clear outcome. The medical conference is the first of its kind. however it was the conviction with which these themes were presented and discussed that showed greatest progress. onset. the genetic variations identified in the GWAS study only account for approximately 11 percent of vitiligo cases. there is now consensus among most leading experts that vitiligo is an auto-immune disease which lies dormant until an environmental trigger causes onset. Italy. Did you attend the congress or would you like to know more about the issues above? Feel free to add a comment below. Firstly. saying that vitiligo was a ‘psychological catastrophe’. Both physicians and those with vitiligo spoke with conviction about the devastating impact vitiligo can have. Further reading: The 2010 Vitiligo World Congress program Visit Vitiligo Corner Visit Vitiligo Cover Lotion Page 85 . spread of disease – it was emphasised that trials must be able to maintain high standards if they are to have a genuine contribution to the effort of tackling the complex disease that is vitiligo. there is a vast area of disease knowledge which still remains uncertain. the rate of repigmentation with selected therapies is often encouraging. but also on their families and friends. while it is clear that there is genetic predisposition to the disease. not only on those directly affected. For example. a number of speakers presented on the challenges faced in the study of vitiligo. The VWC is an ambitious project. Clinuvel attended the first ever Vitiligo World Congress (VWC) in Milan. Unfortunately. to learn more about current issues in treating vitiligo.

com by ‘alexdecarvalho’ on 7 March 2007.Vitiligo Corner 2010 More on Clinuvel’s program for vitiligo can be found at http://www.clinuvel.flickr. More can be found on recent progress with the GWAS study in China in this recently published paper.com/vitiligo. shortly. looking at research priorities. Image reference: ‘MIT Forum hosted at UM’ uploaded to flickr.com/en/blog/discourse/vitiligo-world-congress-2010-%E2%80%93-some-thoughts-and-reflections/ Visit Vitiligo Corner Visit Vitiligo Cover Lotion Page 86 . An introduction to GWAS can be found here.com/photos/adc/414753294/>. http://www.clinuvel. Results from another vitiligo study. <http://www. were presented at the conference and will be published online here.

Sprits took his time to thank Vitiligo Support International. I have understood mainly . When ever I see “before and after photos” on the internet it remands me only Photoshop trick.Vitiligo Corner 2010 38 Comments » Hana said: This is the report I got from a member on other forum in Us. Visit Vitiligo Corner Visit Vitiligo Cover Lotion Page 87 .R. according to others who explain to me this research is important to understand what made the antibody cells attack melanocytes. Finnaly He says “ we have got the street we are looking for the addresses” Another researcher who comes clause to find the underlying cause is Dr. but thanks to this forum we have learned a lot. The only different is it feels so good when you hear the updating from the right people with some evidence and data but most remains still just as theory . generally it was about possible link between Keratinocyte expression of p SAT3 .. If the other autoimmune diseases find the gene then we are automatically inn . most of the topics and issues are discussed here before. I was afraid not to understand what they going to talk about on the scientists days. Truly hope on 1st Vitiligo World Congress Thursday September 30. it will make it easier to find the main cause. and it show that there is big hope that they have seen a light on the tunnel.he explained it in a very easy way .his presentation was heavy to understand for me it was on the scientists day explanation was only medical and biological symbols combinations . Atsushi T. it really gave me a confidence that there is some thing we can do. he mentioned that there is a huge amount of fund and research on the other autoimmune disease which have some common similar genes with vitiligo. Vitiligo support internatinonal.Spritz had a wonderful presentation on recent advances in genetics of vitiligo . Dr. Dr. but now when I saw doctors and researchers show on the presentation before and after photos watching us the progress and the surgical evidences in front of other leading scientists. from Japan.it is about infiltration of TH17 cells in to vitiligo skin. 2010 8:30 AM Last weekend I followed the three days conference where the leading top scientists and Clinicians of vitiligo were participated in Milano. Since I m not a medical person . for cooperating and playing a key role in the study by helping to recruit participants.

The information was not clear for me I didn`t get a chance to ask him. This latest techniques is already in use. I could have tried this treatment but I have decided first to stop and arrest the further depigmentation with protopic and NB UVB. Inflammation . it was really impressive. its commercial equipment was advert for other dermatologists out side.I wanted to listen her theory and treatment in front of other leading researchers.Vitiligo Corner 2010 I was disappointed that Prof. Please can VSI clear it out . Boissy from US show us photo how some industry chemicals can depigment the skin in the laboratory test .it shows how melanocytes which present in the scalp hair follicles can be used to treat depigmented skin.the common issues on the presentasions were tings which we heard about before . They have experienced that when they implant the cell for example on the right cheek the pigmentation has achieved on the left cheek too. some of the vitiligo trigger chemicals which we can find in a daily supermarket product like deodorants. R.he explaind industrial or commercial phenolic compounds can first develop occupational vitiligo then it can activate the general vitiligo in the body. oxidative stress. Other interesting presentation was about environmental factors which can be trigger to general vitiligo. . household removers. He didn`t mentioned it . according to the dermatologist adverting the technology he said that this treatment helps even for active non segmental vitligo too.sops. k. If it is in use which are the most usual phnols in cosmetic products which we uses dayly. he metioned that some of this bad phenols are not in use.. Visit Vitiligo Corner Visit Vitiligo Cover Lotion Page 88 . Schallreuter didn`t come . I had a plan to take her treatment but after the conference I drop it coz I lost confidence on her treatment.is it safe ? may be scientists has found out that it is not bad any more . About Phenoxyethanol which there were discussion about it on this forum.she was supposed to present on scientists day . dr. Most topics ware based on research . E. What makes this treatment unique is while all the other cell therapies and skin grafting treatments require stable vitiligo . By the way there were many tables outside adverting variety of products and cover cosmetics. sulphydris: Hydroquinone I have noted only few. hairdye. it is about free radicals. On the treatment base were Ultraviolets and photothrapy immunomodulator ointments and steroids I will just make some notes on facts and thories though most of notes are which we know already. Boissy and ask him if these chemicals are out of cosmetic products.. One of the best treatment I have observed is Cell transplantation which is presented by Thomas Hunzikeris from university of Burn in Switzerland It was very interesting :. vitiligo trigger chemicals phenols : Catechol dervatives.roll of antioxidants. treatment :. I thought the presentation will be on website or we get it on cd but it didn`t happen the handbook we got has no all information . Please admin (VSI) can you contact dr..

Smida Rached mentioned that it is good to consume foods that contain omega 3 and 9 and avoid oils that contain omega 6 and he was explaining about good and bad cholesterols If I am not mistaken I think he had a medical trial on this theory . one of elderly Indian doctor who has expriance with over 18000 patents claim taking lime juce affect the medication progress of his patents.Steroids halp to stop arrest the further depigmentation .moderate sun exposure is important to stimulate pigment cells.NB UVB and Tacrolimus (Protopic) are mostly helpful for nonsegmental vitiligo.Vitiligo is an autoimmune disease. He has developed orally taken oil which can help vitiligo he is working to get approved in Tunisia. .Children from vitiligo parents they have 6-7 % of chances of possiblity to inherited vitiligo genes combination. .Hashimoto’s thyroiditis. .One of the Italian researchers has shown also early age smokers are more exposed to vitiligo . . It doesn`t necessarily mean that they will develop vitiligo in there life .There is no any scientific evidence about which diet is good or bad for vitiligo.lupus . . in which the body attacks itself. but one of the scientist Dr. . spritz . it is good if VSI give us comment about vitamin C.Some doctors has discovered that a lack of vitamin D 3 is common deficiency in vitiligo patents. There is a scientific evidence on use of Tacrolimus ointment (Protopic) and NB UVB treatment. .too much is not good as sun has all the rays that can damage our skin. I took only those I remember. cellular grafting.The vitamin C usage is still unclear for me. . By Dr.Some genes that showed up in a people with vitiligo were associated with other autoimmune disorders such as Type I diabetes .One of the clinicians has shown use of ginkgo biloba has helped some of his patients. Other say vitamin C is an excellent antioxdant .Vitiligo Corner 2010 . I followed this because I have lack of vitamin D3 . It is SAFE SAFE SAFE even for children’s as long as it is monitored by dermatologist. balanced diet and life style is good. micropigmentation works for stable segmental vitiligo.Most techniques like adult stem cell therapy. Generally variety and healthy. Visit Vitiligo Corner Visit Vitiligo Cover Lotion Page 89 . .

there must be a connection between psychological stress and antibodies. I really recommend to all vitis friends to attend when ever there is conference about vitiligo near you . The Search function is located on the Community menu. I am so happy and proud that I attend the conference specially meeting and ask to the known scientists really give me a confidence to continue with my treatments. Most of all . listening to all this experts theory and fact from almost all the continents most from Europe. and you can go back several years. 2010 3:01 PM Thanks for the report! Hopefully. I would think it would be very difficult to completely avoid. It was a very useful and interesting congress. Vitamin C is one of those things that bothers some people. though I don’t believe phenoxyethanol is mentioned. We have had several discussions here on it. watching how eager the researchers are gave me a real hope that soon they will have understanding what causes vitiligo. There are tables about what products contain phenols. It is found in so many products. I think when we stress our adrenalin gets high and it affect the antibodies they get intoxicated and start to attack our melanocytes .Less stress is important specially when we take treatments it is very important to control stress. All the topics you mention have been discussed either in past newsletters or here in the forums. I believe there’s one post called Vitamin C: Friend or Foe that Lorraine posted a few years ago that had a lot of discussion. while for others it’s fine. however. I am not english speaker . Thanks for reading! Bamsegutt Message #199224 VitiligoMom RE: Truly hope on 1st Vitiligo World Congress Friday October 1. as it is almost entirely devoted to the oxidative stress/phenols issue. you have received our most recent newsletter. Visit Vitiligo Corner Visit Vitiligo Cover Lotion Page 90 .Vitiligo Corner 2010 .I hope you all understand my English .

# 3 October 2010 at 7:56 pm * Mary said: Continuation of previous post (sorry)……as it seems to me. I’m so thankful for all the information.to be cured. as it seems to me. Vitiligo does not have to be segmental or have a border. thank you. That is the first time I have heard about cell transplantation for non segmental vitligo. I know in my heart that there will be a cure in my lifetime. Even more exciting is when treated with this cell transplantion. The Cell transplantation info is so fascinating. That is really exciting because. it can effect the other side of the body as well. Vitiligo does not have to be segmental or have a border. Thank you. Non segmental Vitiligo develops symmetrically on the body and now it seems it may be cured that way also. It gives me such hope that these researchers are so focused on Vitiligo. Fascinating. that now.Vitiligo Corner 2010 Glad you enjoyed it! Cindy # 3 October 2010 at 8:46 am Mary said: Hana. that now. # 3 October 2010 at 8:04 pm Visit Vitiligo Corner Visit Vitiligo Cover Lotion Page 91 . thank you! for your post.

# 5 October 2010 at 4:15 pm Visit Vitiligo Corner Visit Vitiligo Cover Lotion Page 92 . they rather spend money on findind cure for cancer or aid is sad but is true.i been to alot of vitiligo forms and there are alot of young peeople has vitiligo and say how bad the vit has on them…for me too this has a big downside to the mental health… # 5 October 2010 at 11:17 am * Lee Ha said: if the have the fund they can find the cure in one year but you all know that government does not really care about vit patients becuase it is not going to kill us. # 5 October 2010 at 12:19 pm * d said: hi why are they spend money on mental heath…counceling ect… then…why dont they put some money on vit research caz people has all those problem…it can damge our mental health relly bad….Vitiligo Corner 2010 d said: the scientise has or better to find a cure or treatment soon because there are more and more people is geting this desea and the age is geting younger and younger……even alot of babys gets vitiligo…..

J’ai aussi un numéro de téléphone pour le joindre grace à internet 41 31 632 2288 Bonne chance.Vitiligo Corner 2010 catherine said: Bonjour ZZ. il s’agit du docteur HUNZIKER à l’université de BERNE en SUISSE. Catherine # 7 October 2010 at 8:56 am * Lee Ha said: Thank you Catherine can someone please translated # 7 October 2010 at 9:13 am * zz said: what is the point of this world congress?????they not even doing anything new????? # 13 October 2010 at 8:39 am * Visit Vitiligo Corner Visit Vitiligo Cover Lotion Page 93 . En réalité. Il ya une erreur concernant le nom du médecin.

. more importantly at this very moment. and if you’d like to rest on a more cynical view. Dr Mulekar says. zz.000 people in the UK who suffer from this condition and treating those with stable vitiligo in a safe and professional environment. and every scientist is racing to be ‘the one’ who found it and claim the notoriety. is called Melanocyte Keratinocyte Transfer (MKT) and involves the transfer of melanocytes from an area of healthy skin to an area of skin which is suffering from white vitiligo patches and contains no melanocytes. was for all of the sectors involved with vitiligo to get together to discuss what they know. thanks to the pioneering research and development of specialist dermatologist Dr Sanjeev Mulekar. be able to coordinate their efforts to find a cure and. My clinic at the Wimpole Centre is aimed at helping some of the 600. just know that nothing would be more profitable for the companies involved than to have the illustrious ‘cure for vitiligo’. here’s the one thing you should hold on to: people around the world care and everyone of them is doing their best because this is what they spend their lives working on. # 13 October 2010 at 9:01 am * zz said: now the congress is over…. The treatment.to share information with each other in an attempt to unify and. which is suited exclusively to stable vitiligo.Vitiligo Corner 2010 Nathalie Pelletier vitiligocover. hopefully.” # 2 November 2010 at 4:51 pm Visit Vitiligo Corner Visit Vitiligo Cover Lotion Page 94 . “Vitiligo affects people the world over. improve the quality of life for everyone living with vitiligo.what treatment are they working on now…. # 28 October 2010 at 10:34 am * Lala said: A remarkable vitiligo treatment is now available at the Wimpole Aesthetic Centre in London.com (author) said: The point of the world conference.

13 years ago the internet wasn’t as powerful as it is now! There is more awareness and the message is getting out there. The only way there will be more awareness is if we make it more aware.Vitiligo Corner 2010 Mary said: Hi Lala. Also. If they see a need and they think they will make money on it. Visit Vitiligo Corner Visit Vitiligo Cover Lotion Page 95 . Does anyone know though if it can come back in those areas treated on the body? Anywho. The more clinics doing it. if they offer this. At least it will help people with stable Vitiligo. This was not the case a couple of years ago. start a support group or canvass your area representative. start to ask clinics around you. why don’t you become more active in your community. the cheaper it will become for all of us. Rather than complaining all the time. Do some research. The pictures are amazing! Is this the same procedure that they did in Iran recently? I’m definately staring to see more and more clinics around the world doing this. Thanks for the update on this clinic. they will do it. this is still amazing…Yipeee! # 2 November 2010 at 5:11 pm Mary said: zz.

Vitiligo Corner 2010 Negativity will not help your condition. which made them more aware that there was a need and it may come to fruition faster now because of the response. Tissue ingathering.does anyone know where we can take this treatment…. and as far as I know Wimpole is the only clinic in Europe which offers this procedure. as well as easy-to-use patented ’spray-on’ practical application process. God knows it can be hard but at least we’re not alone. a positive mind will yield positive results! # 3 November 2010 at 6:46 am * Mary said: Look at the Scenesse product. acquired on at the very time of the process. cell sequestration as well as the preparedness of the cell suspension system takes in more or less twenty to thirty minutes in total within which time the discourse surface area is Visit Vitiligo Corner Visit Vitiligo Cover Lotion Page 96 . we saw it on the internet. The ReCell® is actually a complete.its cheaper the mkt…. fast as well as autologous cell gleaning. It’s all good! # 3 November 2010 at 6:49 am Lala said: I have been for the consultation which cost me £150. we posted it on this blog.ands its almost the same effect. to be worked on into a prompt cell population for the delivery onto the very surface area of the discourse sphere applying an extremely effective. we have to stay positive. but will probably differ in patients depending on how extensive your vitiligo is. the ReCell in reality enables up a slim split thickness biopsy. Highly-developed as actually an ‘off-the-rack’ kit.. lots of us started to call and email the company. processing & deliverance new technology that in reality enables operating surgeons as well as the clinicians to care for skin defects employing the patient’s very own cells within a re-generative procedure. I agree with Mary guys. # 3 November 2010 at 6:27 pm * zz said: got this infro from a website…. The price I have been quoted on this is £3000.

donor sites. # 4 November 2010 at 11:14 am Visit Vitiligo Corner Visit Vitiligo Cover Lotion Page 97 . modest to restrained scars.Vitiligo Corner 2010 actually set up. my doctor said if you have segmental vitiligo it will spread fast then it will stop for good. if you have vitiligo say on both of your elbow or both side of the body that type is really hard to treated. reconstructive. When prepared. glabrous wounds. fibroblasts. The ReCell has actually been clinically demoed to speed up the healing part. melanocytes. For the Vitiligo patients it is pretty overmuch important because of the very fact that the ReCell technology eventually enables up the cell processing on and at the very surface area of discourse without the usance of speciated research lab faculty. derogate the scar formation. The ReCell in reality enables up the very deliverance of the keratinocytes. # 4 November 2010 at 9:09 am * lee ha said: ZZ how is your vitiligo treament going sir? you do have any new spots? if not you in a good shape. and is as well important for the Vitiligo bearers because of being both price as well as time effective. do away with the tissue rejection as well as re-introduce the very pigmentation within the hypo pigmented surface areas. It has as well been contrived up for the employ within an all-inclusive forms of bruises. the cell suspension is then on ready for prompt use as well as could cover up a discourse surface area of equal to eighty times the surface area of the donor biopsy. burn marks as well as aesthetical procedures letting in burn marks as has been stated previously & blisters. the hypopigmentation which includes Vitiligo as its main constituent as well as within aesthetic rejuvenation processes. as well as the Langerhans cells gleaned in from the dermal-epidermal juncture for practical application onto a wreathed surface area in order to actually elevate speedy as well as efficacious healing. this type of vitiligo does not associate with auto immune diease. plastic.

ect…. # 4 November 2010 at 1:42 pm * lee ha said: ZZ i have couple spots on my facial area. my doctor said mine vit does not look that bad she also said if nothing work for me she will performance skin graft for me. Melanocyte Keratinocyte Transfer (MKT) (too expensive). for now i just wait and hope now now spots pop up.I am truley fed up with this condition. there will be more treatments…like the recell treatment…. the named of the hospital is ford hospital. I have read most of the commments and suggestions.have you had any sucess with you treatment…. I am very depressed with this condition.My technican who does the treatments noticed some improvement.where is your vit….Vitiligo Corner 2010 mary said: Hi natalie and all others . I also drink lots if carrot juice. in order to to skin graft your vitiligo or my has to be stable for at least one year.or what about the red chili with vodka combo. one on the eye lid and one on the side of the nose. help pls. are there any pictures of comparisons.. # 4 November 2010 at 11:45 am * zz said: hi lea ha how is you vit goin along too…my vit is next to my eye and under my chin…. The treatment are expensive 100 and up per session.IS there a support group in my province..I feel those who do not have vit truely do not get it . leg and back. Visit Vitiligo Corner Visit Vitiligo Cover Lotion Page 98 . so far it does not spread on me thank god for that. I PRAY MY CHILD DOES NOT GET IT.. I am under the supervision of the dermatologist but do not get to questions him much. i have been using protopic and uvb along with all type of veggie not red meat..I was questioning the peperine approach. i can do mkt too the hospital is in detroit michigtan usa. It feels good to know every one is trying to find some type of cure! I am prensently using the excrimer 308 laser along side steroid and protopic creams.But there has been an off again on again treaments.I TAKE VITAMINES. just relax man when we die the skin going to have to be burn anyway.I noticed spots on my hand.be paient and wait a few more years. does any one know where to get it in Quebec.

Vitiligo Corner 2010 # 4 November 2010 at 2:12 pm * SV said: truly ppl without vitiligo don’t get it … I’m jst praying that i pass versity this year. It has been extremely hard sometimes feel like giving up # 4 November 2010 at 4:48 pm * zz said: lee ha its good that you get to do mkt and skin graft in usa but in england there is no mkt or skin graft in normaly hospital in england….i will ask my derm to see if i can do skin graft next time i see her….but i saw on the website that there is no skin graft on the nhs… # 4 November 2010 at 6:22 pm lee ha said: zz if i want to do mkt i have to fly to Detroit Michigan about 2 hours to see the doctor first you cannot just schedule and have mkt done. doctor said we need to see you first in order for us to work on you that mean i have to go back two to three time if to choose to do it. # 5 November 2010 at 6:22 am * VEN said: Hello Visit Vitiligo Corner Visit Vitiligo Cover Lotion Page 99 ..

please do your research before getting it done.????? # 5 November 2010 at 10:53 am zz said: Visit Vitiligo Corner Visit Vitiligo Cover Lotion Page 100 . I dont think living in northern hemisphere where sunlight is minimal helps us. V # 5 November 2010 at 8:33 am * zz said: lee ha did your derm tell you how much it would cost you to do mkt????its in a normally hospital so it should cost cheaper….there is one derm/clinic in englnad that is in london that does mkt but its privet and it cost really really expensive…?i really wish that they do this type of treatment on normally hospital or cheaper…not many people can afford £3000 or £4000 thousand pound for this treatment…bigger area of vit may cas 10s thousand of pounds…does anyone know how we cound make the doctors to treat our condition……why is it that when they know that this treatment works and not use it to treat us with this type of treatment.Vitiligo Corner 2010 Mary. I think Canadian’s will have access to it before people in the states I would suggest you to follow up with Clinuvel or Canadian Clinical Trial. I suggest want to suggest that anything with Skin Graft or plastic surgery is recommended for people whose vitiligo is not spreading and their is not guarantee that the spots willnot come back also this procedure is expensive. I tried one from a pharmacy in NYC ( 90% peprine) and I saw two small spots after few days of applying and as I am Lazy ( work etc. I think you should start your own support group and try to get people with the condition. you should be able to get peprine from any vitamin shoppe or Herbal center. when I spoke with Clinuvel with the new implant they are testing according to them they have started/ or close to start a Clinical trial in Canada. One more intresting thing for you to follow on.) I didn’t continue it... V # 5 November 2010 at 7:51 am VEN said: Lee Ha/ZZ.

This is the only clinic of its kind in the UK. Visit Vitiligo Corner Visit Vitiligo Cover Lotion Page 101 . Vitiligo is a common non catching skin condition affecting around 1% of the population. Counselling is available with this treatment. Until recently. With world renowned dermatologist and nurse specialist. people suffering from vitiligo have had virtually no access to successful treatment for their vitiligo except for cosmetic camouflage. It can affect people of any age and of any age. Vitiligo can cause extreme distress to sufferers because of its unusual appearance. Dr Chopra has a special interest in vitiligo and has had many years experience of treating patients with vitiligo both in NHS and private practice.i have found that there is a clinic that does recell treatment for vitiligo…recell treatment is a great treatment for vitiligo…here is the information i found… look out for the recell treatment… Vitiligo Clinic Due to massive demand Dr Sunil Chopra is delighted to announce a clinic specialised in the treatment of vitiligo. Treatments available: • Assessment – Dr Chopra will thoroughly assess your vitiligo and medical history and discuss the best treatment options available to you.Vitiligo Corner 2010 hi people that live in london. • Depigmentation – for patients with very extensive vitiligo. The London Dermatology Centre is able to offer the most successful proven treatments available to give the skin the best chance of repigmentation. i have found some greatment news….. • ReCell – a procedure where the colour forming cells of ‘normal’ skin are grafted on to areas of vitiligo. • Phototherapy – (UVB-TLO1) and PUVA an ultraviolet light treatment which has good results in repigmenting vitiligo. • Counselling – we have a counsellor on site who is available to discuss issues relating to vitiligo and how to cope with it.

That’s fantastic! Doesn’t if feel good to be doing something. # 5 November 2010 at 1:53 pm Mary said: Hey zz. thanks so much! # 6 November 2010 at 6:36 am * zz said: Visit Vitiligo Corner Visit Vitiligo Cover Lotion Page 102 .Vitiligo Corner 2010 # 5 November 2010 at 11:31 am * zz said: am in manchester i will go to this clinic soon to get the recell treatment that is for my face.. # 5 November 2010 at 11:32 am * lee ha said: Congrats ZZ let know how it goes okay. and you will help all of us by letting us know your results.

Vitiligo Corner 2010 people from london could you also go to this clinic and and ask about the recell treatment tooo and ask how much would it cost.(work)…but its good to know that the recell treatment is already in use and also for vitiligo….thanks # 6 November 2010 at 10:16 am Visit Vitiligo Corner Visit Vitiligo Cover Lotion Page 103 ...i have to wait a few months till i got time to go down to london….

increase awareness about vitiligo. 4. but many are able to step out of their own world to focus on bettering the lives of those around them. it is a very important cause that affects millions of people world-wide. I got an idea. In the end. and I will put a ‘donate now’ button on here to collect the monies to give. leave a comment with some potential charities we could support. Immediately I thought of us and our many quests: to find a cure for vitiligo. So off I went to their website to begin. help others 6 Comments This morning I heard a commercial for the Pepsi Refresh Project. and what I found was a jolt of reality. there were a few nonessential ones mixed in. and thankful that there are so many people in our world who care and want to help others. After all. 1. If you’re with me. Visit Vitiligo Corner Visit Vitiligo Cover Lotion Page 104 . businesses. Create a sensory room for students with autism and other disabilities. too) I felt thankful. What if we. That’s really quite amazing when you think about it. Thankful that vitiligo is not life-threatening. Surely. They are looking for people. Once I read through a page or 2 of these requests (and mind you. Each and every one of us on earth has not-so-nice issues that we deal with every day. our actions may inspire others to give…and perhaps this would lead to worldwide attention to vitiligo. I thought. Dance & Art Therapy for Children with Autism and their Families. Make gowns for cancer patients when hospice is called into the home. became benefactors (supporters) of a selected charitable foundation? Not only would we be helping others. our collective group of people with vitiligo. and our desire to learn how to deal with the emotional effects of living with vitiligo. Buy an Arm Bike so that disabled patients can exercise in our gym. Here’s how it works: you post your cause. 2. and non-profits with ideas that will have a positive impact and Pepsi is giving away millions of dollars to fund them. and the ones with the most votes each month get funding.Vitiligo Corner 2010 Vitiligo can help us. 3. With this in mind. people vote for their favorites. 5. if I can write a great essay about our plight we would get money. we’ll vote on one. Create a garden to help support the local food bank.

Vitiligo Corner 2010 P. I decided to donate 5% of the net profits from Vitiligo Cover Lotion sales to the John Dau Foundation. Visit Vitiligo Corner Visit Vitiligo Cover Lotion Page 105 . and their life from the refugee camp to America. Here is the official description of the documentary. And please go here if you would like to read a bio about John Dau. “God Grew Tired of Us”. a documentary which tells the story of 4 young Sudanese men who were a part of the ‘lost boys’.my own just would not do it justice.S. After watching.

What do you think Natalie? # 17 October 2010 at 10:08 am # Nathalie Pelletier vitiligocover.com (author) said: Hi Mary! I love the idea about supporting skin cancer research or anything connected to it such as rehabilitation. yet scientists are developing a cure for melanoma using the skin cells taken from the white patches of people with vitiligo. or Lupus. # 17 October 2010 at 2:19 pm Visit Vitiligo Corner Visit Vitiligo Cover Lotion Page 106 . It’s pretty interesting that people with vitiligo are told to stay out of the sun because we are at higher risk of getting skin cancer. but possibly we could target skin cancer specifically. It’s one of the fasted growing cancers. In our region here in Ontario it is the highest of all of Canada.Vitiligo Corner 2010 6 Comments » Mary said: I’m with you 100% I think something to do with skin cancer would be good. Another idea would be another autoimmune disease. like Diabete. It would go to the Cancer Society of course. There is also the connection with Vitiligo.

Places to visit Vitiligo Corner Vitiligo Corner on Facebook Vitiligo Corner Facebook Fan Page Vitiligo Corner on Twitter Vitiligo Corner on YouTube Vitiligo Group on LinkedIn Vitiligo Corner on FriendFeed Free Vitiligo ebooks Copyright info The copyright of this work belongs to the author who is solely responsible for the content. USA. your website. started a few Internet companies. California 94305. You can print out pages and put them in your favorite coffee shop’s windows or your doctor’s waiting room. To view a copy of this license. Visit Vitiligo Corner Visit Vitiligo Cover Lotion Page 107 . Cover image from iStockphoto® WHAT YOU CAN DO You are given the unlimited right to print this manifesto and to distribute it electronically (via email. She’s written 10 other ebooks. This work is licensed under the CreativeCommons AttributionNonCommercial-NoDerivs License. though. You may not alter this manifesto in any way. visit Creative Commons or send a letter to Creative Commons. Subscribe Sign up for our free e-newsletter to learn about our latest opuscules as soon as they are available.Vitiligo Corner 2010 Our Sponsor About the Author NATHALIE PELLETIER is the creator of Vitiligo Corner. or any other means). and you may not charge for it. or you can hand out copies to everyone you meet. 2009 and is based on the best information available at that time. You can transcribe the author’s words onto the sidewalk. and writes a blog. Born on date This document was created on February 26. Stanford. 559 Nathan Abbott Way.

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